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The map label for this gene is csd [H]

Identifier: 150398179

GI number: 150398179

Start: 3129485

End: 3130762

Strand: Direct

Name: csd [H]

Synonym: Smed_2982

Alternate gene names: 150398179

Gene position: 3129485-3130762 (Clockwise)

Preceding gene: 150398178

Following gene: 150398180

Centisome position: 82.75

GC content: 60.49

Gene sequence:

>1278_bases
ATGGCCGCCAACGCACAGCTAGATATCGATTTCGCGCGCAGTCAGTTCCCGGGCCTCGAACTCGGCTGGACCTTTTTCGA
CAATGCCGGCGGATCGCAGATCCTCAAGGGCGCGCTCGAGCGCATAAACACCTTCCTTATCGAGAAGAACGTTCAGATCG
GCGGTTCCTATGCGGTGTCGCAGCATGCGGCCAAGGCGCTCTACGAGGCCCGCACAGCCGGGATGCATCTCGTTAATGCG
AGCCGGCCGGAAGAAATCGTCTTCGGCAGTTCGACGACGGCGCTTCTCCAGAACCTGGCTCGCGCCATGGCGAGCCAGCT
TGCGCCGGGCGACGAAATCATCGTCACGGTGAGCGACCACGAATCCAATATCGGTCCTTGGGACCGGTTGCAGGCAGCGG
GCATCGTTCTCAAGATCTGGCCGCTCGACAAAAAGACCCTGACCCTTGACCTCGCCGACCTCGAACCTTTGATGGGCGCA
CGCACGAAGCTCGTCTGCGTGCCCCATGCTTCCAACATTCTCGGCTCGATCAACCCGGTCCGCGAAATTGCCGATTTCGT
CCACGCCCGAAACGCGAAACTATGCGTCGACGCGGTGGCTTACGCGCCGCACCGCGCCATCGACGTACAGGCCTTCGACG
CCGACTATTATGTCTTCAGTCTCTACAAGACCTATGGGCCGCACTATGCGCTGATGTACGGCAAATATGATCTGCTGCTC
GAGCTGGATACGCTCTACCACTACTTCTACGGCAAGGATAAGGTTCCAGGAAAGCTCGAGCCAGGCAATCCGAACTATGA
GCTCGCCTATTCGACCTGCGGGATCGTCGACTACCTTTGCGAGCTCGGCGCCCGCTCCGGAGAAGCCGGCACTGTCAGGC
GAAAGATCGAGGCCGCCTTCGATGCGGTGGCCAGCCAGGAGGACGCCCTGACCGAGCGGCTCCTCTCCTATCTGCGCTCG
CGCAACGACTGCCGGATCATCGGACAATCGGTCAATCGCGACAGCCAGCGCGTGCCCACCATTTCCTTCCGCTTCGACGG
ACGCGATGCTGCAGAACTCTGCAAGGCGATCGACGAGGAGAACATTGCCATTCGCCACGGCGATTTCCATTCCCGCCGGC
TTGCCGAGTATCTGGAGCTGACCGATTACAACGGCATGCTGCGCGTCTCCATGGTGCATTACAACACGATCGAGGAAGTG
GATCGTCTCACGGCCGCCTTCGACCGGGTTCTTTCGACCGGCACCGGAAACACAGCCGATGCAAGGCGCGCCGGATGA

Upstream 100 bases:

>100_bases
CCGTCGGATATTTTCGACAGCCCTCGCGAGGAACGGACACGCGGCTTCCTGCGCGCAGTCCTCAATCATTGAACAAACTC
TTTTCCGGAGAACGCCAAGA

Downstream 100 bases:

>100_bases
GCCAGAAAGGGCCGGCCATGCGCTTCGATAAGGTCATCCGTTATGGAACGGTCGTCACCGCCAGCGATACATTCAAGAGC
GATGTCGGCATTAAGGAAGG

Product: cysteine desulfurase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MAANAQLDIDFARSQFPGLELGWTFFDNAGGSQILKGALERINTFLIEKNVQIGGSYAVSQHAAKALYEARTAGMHLVNA
SRPEEIVFGSSTTALLQNLARAMASQLAPGDEIIVTVSDHESNIGPWDRLQAAGIVLKIWPLDKKTLTLDLADLEPLMGA
RTKLVCVPHASNILGSINPVREIADFVHARNAKLCVDAVAYAPHRAIDVQAFDADYYVFSLYKTYGPHYALMYGKYDLLL
ELDTLYHYFYGKDKVPGKLEPGNPNYELAYSTCGIVDYLCELGARSGEAGTVRRKIEAAFDAVASQEDALTERLLSYLRS
RNDCRIIGQSVNRDSQRVPTISFRFDGRDAAELCKAIDEENIAIRHGDFHSRRLAEYLELTDYNGMLRVSMVHYNTIEEV
DRLTAAFDRVLSTGTGNTADARRAG

Sequences:

>Translated_425_residues
MAANAQLDIDFARSQFPGLELGWTFFDNAGGSQILKGALERINTFLIEKNVQIGGSYAVSQHAAKALYEARTAGMHLVNA
SRPEEIVFGSSTTALLQNLARAMASQLAPGDEIIVTVSDHESNIGPWDRLQAAGIVLKIWPLDKKTLTLDLADLEPLMGA
RTKLVCVPHASNILGSINPVREIADFVHARNAKLCVDAVAYAPHRAIDVQAFDADYYVFSLYKTYGPHYALMYGKYDLLL
ELDTLYHYFYGKDKVPGKLEPGNPNYELAYSTCGIVDYLCELGARSGEAGTVRRKIEAAFDAVASQEDALTERLLSYLRS
RNDCRIIGQSVNRDSQRVPTISFRFDGRDAAELCKAIDEENIAIRHGDFHSRRLAEYLELTDYNGMLRVSMVHYNTIEEV
DRLTAAFDRVLSTGTGNTADARRAG
>Mature_424_residues
AANAQLDIDFARSQFPGLELGWTFFDNAGGSQILKGALERINTFLIEKNVQIGGSYAVSQHAAKALYEARTAGMHLVNAS
RPEEIVFGSSTTALLQNLARAMASQLAPGDEIIVTVSDHESNIGPWDRLQAAGIVLKIWPLDKKTLTLDLADLEPLMGAR
TKLVCVPHASNILGSINPVREIADFVHARNAKLCVDAVAYAPHRAIDVQAFDADYYVFSLYKTYGPHYALMYGKYDLLLE
LDTLYHYFYGKDKVPGKLEPGNPNYELAYSTCGIVDYLCELGARSGEAGTVRRKIEAAFDAVASQEDALTERLLSYLRSR
NDCRIIGQSVNRDSQRVPTISFRFDGRDAAELCKAIDEENIAIRHGDFHSRRLAEYLELTDYNGMLRVSMVHYNTIEEVD
RLTAAFDRVLSTGTGNTADARRAG

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787970, Length=428, Percent_Identity=28.5046728971963, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1789175, Length=415, Percent_Identity=28.6746987951807, Blast_Score=126, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 47014; Mature: 46882

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAANAQLDIDFARSQFPGLELGWTFFDNAGGSQILKGALERINTFLIEKNVQIGGSYAVS
CCCCCEEEEEEHHCCCCCCEECEEEECCCCHHHHHHHHHHHHHHHHEECCCEECCCHHHH
QHAAKALYEARTAGMHLVNASRPEEIVFGSSTTALLQNLARAMASQLAPGDEIIVTVSDH
HHHHHHHHHHHHCCEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEECC
ESNIGPWDRLQAAGIVLKIWPLDKKTLTLDLADLEPLMGARTKLVCVPHASNILGSINPV
CCCCCCHHHHHHCCEEEEEEECCCCEEEEEHHHCCHHHCCCEEEEEECCHHHHHCCCCHH
REIADFVHARNAKLCVDAVAYAPHRAIDVQAFDADYYVFSLYKTYGPHYALMYGKYDLLL
HHHHHHHHCCCCHHHHHHHHHCCCCEEEEEEECCCEEEEEEHHHCCCCEEEEECCEEEEE
ELDTLYHYFYGKDKVPGKLEPGNPNYELAYSTCGIVDYLCELGARSGEAGTVRRKIEAAF
EHHHHHHHHCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
DAVASQEDALTERLLSYLRSRNDCRIIGQSVNRDSQRVPTISFRFDGRDAAELCKAIDEE
HHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEECCCCHHHHHHHCCCC
NIAIRHGDFHSRRLAEYLELTDYNGMLRVSMVHYNTIEEVDRLTAAFDRVLSTGTGNTAD
CEEEEECCCHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCC
ARRAG
CCCCC
>Mature Secondary Structure 
AANAQLDIDFARSQFPGLELGWTFFDNAGGSQILKGALERINTFLIEKNVQIGGSYAVS
CCCCEEEEEEHHCCCCCCEECEEEECCCCHHHHHHHHHHHHHHHHEECCCEECCCHHHH
QHAAKALYEARTAGMHLVNASRPEEIVFGSSTTALLQNLARAMASQLAPGDEIIVTVSDH
HHHHHHHHHHHHCCEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEECC
ESNIGPWDRLQAAGIVLKIWPLDKKTLTLDLADLEPLMGARTKLVCVPHASNILGSINPV
CCCCCCHHHHHHCCEEEEEEECCCCEEEEEHHHCCHHHCCCEEEEEECCHHHHHCCCCHH
REIADFVHARNAKLCVDAVAYAPHRAIDVQAFDADYYVFSLYKTYGPHYALMYGKYDLLL
HHHHHHHHCCCCHHHHHHHHHCCCCEEEEEEECCCEEEEEEHHHCCCCEEEEECCEEEEE
ELDTLYHYFYGKDKVPGKLEPGNPNYELAYSTCGIVDYLCELGARSGEAGTVRRKIEAAF
EHHHHHHHHCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
DAVASQEDALTERLLSYLRSRNDCRIIGQSVNRDSQRVPTISFRFDGRDAAELCKAIDEE
HHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEECCCCHHHHHHHCCCC
NIAIRHGDFHSRRLAEYLELTDYNGMLRVSMVHYNTIEEVDRLTAAFDRVLSTGTGNTAD
CEEEEECCCHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCC
ARRAG
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]