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The map label for this gene is gcp [H]

Identifier: 150398162

GI number: 150398162

Start: 3111205

End: 3112287

Strand: Reverse

Name: gcp [H]

Synonym: Smed_2965

Alternate gene names: 150398162

Gene position: 3112287-3111205 (Counterclockwise)

Preceding gene: 150398169

Following gene: 150398161

Centisome position: 82.29

GC content: 66.94

Gene sequence:

>1083_bases
TTGCGCATCCTCGGTATTGAGACTAGCTGCGACGAAACCGCGGCATCGGTCGTCATGCGCGACGAGGAGGGCCGCGGAAG
GATTCTCGGCGACGTGGTGCTGAGCCAGCTGGAAGAGCATAGCGCCTATGGCGGCGTCGTTCCCGAAATCGCCGCGCGCG
CGCATGTCGAGGCGCTCGATACGCTGATCGTAGAGGCGCTGTTGCGCGCCGGCGTCAAGCTTGAGGACATCGACGCGATC
GCCGCTACGAGCGGCCCGGGCCTGATCGGCGGGCTCATCGTCGGGCTGATGACCGGAAAAGCGATCGCACGGGCGACCGG
CAAGCCGCTCTATGCGGTCAACCATCTCGAAGGTCACGCGCTGACTGCGCGGTTGACCGACGAGCTCCAGTTTCCCTATC
TGATGCTGCTCGTCTCCGGCGGGCACACGCAGCTGATCCTCGTCAAAGGTGTCGGTGAATATGAGCGCTGGGGCACGACG
ATCGACGACGCGCTGGGCGAGGCTTTCGACAAGACCGCCAAGCTGCTCGGCCTTCCTTATCCGGGCGGCCCGGCCGTGGA
ACGGGCAGCCCGGACCGGCAATCCGGAGCGTTTCGACTTTCCGCGGCCGCTCGTTGGCGATGCCAGGCTCGATTTCTCCT
TCTCCGGCCTGAAGACGGCCGTCCGGCAGGCGGCGAAATCGCTGGAGCCGGTGACCGAGGCTGACATCGCGGACATCTGC
GCTTCCTTCCAGCGCGCCATTTCCCGCACCCTCAGGGATCGGGTCGGGCGCAGCTTGAAGCGGTTCAAGGCGGAGTCCGC
ATCCGTGGCGCAACCGGCCCTCGTCGTTGCCGGCGGGGTTGCCGCGAACCAGGCATTGCGCCAGACCCTTCAATCGCTCT
GTGACGAGCACGGCTTTCGTTTTGTGGCGCCGCCGCTCTCGCTTTGCACCGACAATGCCGCGATGATCGCCTGGGCCGGT
GCGGAGCGGCTGGCCGCCGGCCTGCCGGCCGACGGACTGGATGTGGCCCCGCGTTCGCGCTGGCCGCTCGACGCCGAAGC
AAAGGCCTTGATCGGCTCAGGCAGACGCGGCGCCAAGGCATGA

Upstream 100 bases:

>100_bases
TCCTTCATGCTCAGACAGACGCACGCCGCTGTGTGAGTTCCGTGTAGCCACCTTTCACTGCGACCGCAATCGTTGAGTAT
AGCACGTGACGTCCCCGCCA

Downstream 100 bases:

>100_bases
TGGAATGAAGATGAAAAATCCGAAGACCGGACCAAAGATCGTGGTCGTCGGGGCGGGCGCCTTCGGAACGGCGCTTGCGG
CCGTGGCCGCCGACAAAGCC

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MRILGIETSCDETAASVVMRDEEGRGRILGDVVLSQLEEHSAYGGVVPEIAARAHVEALDTLIVEALLRAGVKLEDIDAI
AATSGPGLIGGLIVGLMTGKAIARATGKPLYAVNHLEGHALTARLTDELQFPYLMLLVSGGHTQLILVKGVGEYERWGTT
IDDALGEAFDKTAKLLGLPYPGGPAVERAARTGNPERFDFPRPLVGDARLDFSFSGLKTAVRQAAKSLEPVTEADIADIC
ASFQRAISRTLRDRVGRSLKRFKAESASVAQPALVVAGGVAANQALRQTLQSLCDEHGFRFVAPPLSLCTDNAAMIAWAG
AERLAAGLPADGLDVAPRSRWPLDAEAKALIGSGRRGAKA

Sequences:

>Translated_360_residues
MRILGIETSCDETAASVVMRDEEGRGRILGDVVLSQLEEHSAYGGVVPEIAARAHVEALDTLIVEALLRAGVKLEDIDAI
AATSGPGLIGGLIVGLMTGKAIARATGKPLYAVNHLEGHALTARLTDELQFPYLMLLVSGGHTQLILVKGVGEYERWGTT
IDDALGEAFDKTAKLLGLPYPGGPAVERAARTGNPERFDFPRPLVGDARLDFSFSGLKTAVRQAAKSLEPVTEADIADIC
ASFQRAISRTLRDRVGRSLKRFKAESASVAQPALVVAGGVAANQALRQTLQSLCDEHGFRFVAPPLSLCTDNAAMIAWAG
AERLAAGLPADGLDVAPRSRWPLDAEAKALIGSGRRGAKA
>Mature_360_residues
MRILGIETSCDETAASVVMRDEEGRGRILGDVVLSQLEEHSAYGGVVPEIAARAHVEALDTLIVEALLRAGVKLEDIDAI
AATSGPGLIGGLIVGLMTGKAIARATGKPLYAVNHLEGHALTARLTDELQFPYLMLLVSGGHTQLILVKGVGEYERWGTT
IDDALGEAFDKTAKLLGLPYPGGPAVERAARTGNPERFDFPRPLVGDARLDFSFSGLKTAVRQAAKSLEPVTEADIADIC
ASFQRAISRTLRDRVGRSLKRFKAESASVAQPALVVAGGVAANQALRQTLQSLCDEHGFRFVAPPLSLCTDNAAMIAWAG
AERLAAGLPADGLDVAPRSRWPLDAEAKALIGSGRRGAKA

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=341, Percent_Identity=40.1759530791789, Blast_Score=216, Evalue=4e-56,
Organism=Homo sapiens, GI8923380, Length=328, Percent_Identity=31.7073170731707, Blast_Score=135, Evalue=6e-32,
Organism=Escherichia coli, GI1789445, Length=347, Percent_Identity=48.4149855907781, Blast_Score=279, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI17557464, Length=336, Percent_Identity=33.0357142857143, Blast_Score=156, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI71995670, Length=349, Percent_Identity=30.0859598853868, Blast_Score=123, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6320099, Length=370, Percent_Identity=32.4324324324324, Blast_Score=171, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6322891, Length=297, Percent_Identity=28.6195286195286, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI20129063, Length=342, Percent_Identity=35.9649122807018, Blast_Score=208, Evalue=4e-54,
Organism=Drosophila melanogaster, GI21357207, Length=353, Percent_Identity=30.5949008498584, Blast_Score=135, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 37990; Mature: 37990

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILGIETSCDETAASVVMRDEEGRGRILGDVVLSQLEEHSAYGGVVPEIAARAHVEALD
CEEEECCCCCHHHHHHHEEECCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
TLIVEALLRAGVKLEDIDAIAATSGPGLIGGLIVGLMTGKAIARATGKPLYAVNHLEGHA
HHHHHHHHHCCCCEEHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCE
LTARLTDELQFPYLMLLVSGGHTQLILVKGVGEYERWGTTIDDALGEAFDKTAKLLGLPY
EEEEHHHHHCCCEEEEEEECCCEEEEEEECCCCHHHHCCCHHHHHHHHHHHHHHHHCCCC
PGGPAVERAARTGNPERFDFPRPLVGDARLDFSFSGLKTAVRQAAKSLEPVTEADIADIC
CCCHHHHHHHHCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
ASFQRAISRTLRDRVGRSLKRFKAESASVAQPALVVAGGVAANQALRQTLQSLCDEHGFR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEECCHHHHHHHHHHHHHHHHHCCCE
FVAPPLSLCTDNAAMIAWAGAERLAAGLPADGLDVAPRSRWPLDAEAKALIGSGRRGAKA
EECCCHHHHCCCCEEEEECCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRILGIETSCDETAASVVMRDEEGRGRILGDVVLSQLEEHSAYGGVVPEIAARAHVEALD
CEEEECCCCCHHHHHHHEEECCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
TLIVEALLRAGVKLEDIDAIAATSGPGLIGGLIVGLMTGKAIARATGKPLYAVNHLEGHA
HHHHHHHHHCCCCEEHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCE
LTARLTDELQFPYLMLLVSGGHTQLILVKGVGEYERWGTTIDDALGEAFDKTAKLLGLPY
EEEEHHHHHCCCEEEEEEECCCEEEEEEECCCCHHHHCCCHHHHHHHHHHHHHHHHCCCC
PGGPAVERAARTGNPERFDFPRPLVGDARLDFSFSGLKTAVRQAAKSLEPVTEADIADIC
CCCHHHHHHHHCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
ASFQRAISRTLRDRVGRSLKRFKAESASVAQPALVVAGGVAANQALRQTLQSLCDEHGFR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEECCHHHHHHHHHHHHHHHHHCCCE
FVAPPLSLCTDNAAMIAWAGAERLAAGLPADGLDVAPRSRWPLDAEAKALIGSGRRGAKA
EECCCHHHHCCCCEEEEECCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]