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The map label for this gene is gpsA [H]

Identifier: 150398161

GI number: 150398161

Start: 3110205

End: 3111200

Strand: Reverse

Name: gpsA [H]

Synonym: Smed_2964

Alternate gene names: 150398161

Gene position: 3111200-3110205 (Counterclockwise)

Preceding gene: 150398162

Following gene: 150398160

Centisome position: 82.27

GC content: 66.47

Gene sequence:

>996_bases
ATGAAGATGAAAAATCCGAAGACCGGACCAAAGATCGTGGTCGTCGGGGCGGGCGCCTTCGGAACGGCGCTTGCGGCCGT
GGCCGCCGACAAAGCCAATGTCACGCTGCTTGCGCGGCGGGAGGAAGCGGCTGAGGAATGCCGCCGGACCGGGCGCAACG
AGGCGGCTTTGCCGGGCATCCCGCTTCCGGCAGGCCTTTCCTATTCCTCGCAGGCTGCCGCGCTCGGAGATGCCCACATC
GTGCTCTTTGCAATGCCTTCGCAGGCGCATCGCGACGCGGCGCGTCGTTACGGCGATGCAATCGGCGCCAAGGCGATCGT
CGTCACCTGCGCCAAAGGCATGGAGCAATCGACCGGCCGGCTGCTCACCGACGTGCTCGACGAGGAGTTGCCGGGCCGCC
GCATCGGGGTGCTTTCCGGCCCGGGCTTTGCGGCCGATATCGCCAAAGGACTGCCGACGGCGATGGTGATCGCCGCTCCT
GACCGGGCGATCGCGACGGAACTCGCAGAGGTGCTTTCCGGGCGGACGTTCCGGCTCTATCCCTCGGCCGATCGCACCGG
CGTTCAGCTCGGCGGAGCGCTCAAGAACGTGCTCGCAATCGCTTGTGGCATCGTCGAGGGCGCAGGCCTTGGGGATTCTG
CCCGTGCGGCGCTGATCTCGCGCGGGCTTGCCGAAATGTCGCGCTTCATCGTAGCGAGAGGGGGCGACGCCGATACGGTG
CGCGGTCTCTCGGGATTGGGCGACCTCGTGCTGACTGCGACCAGCCACCAGTCGCGCAACCTGCGATTCGGCATAACGCT
CGGCAAGAGTGGCCGCGCCGAGGGAAGCGGCGAGCTGGTCGAAGGTGCCTTTGCCGCATCCGTCGCCGCTCGCGTGGCGG
GAGAACTCGGTATCGATATGCCGATCACCGAGGCCGTAGCGGCCATCGTCGACGGGAAGCTCGATGTCCGCTCGGCTCTC
GAACAACTGATGTCCAGACCGATCACCCACGAATAA

Upstream 100 bases:

>100_bases
GCCGACGGACTGGATGTGGCCCCGCGTTCGCGCTGGCCGCTCGACGCCGAAGCAAAGGCCTTGATCGGCTCAGGCAGACG
CGGCGCCAAGGCATGATGGA

Downstream 100 bases:

>100_bases
TTCTCCAGGAGGATCCATGCTCTTCGCACTGCTCTGCACCGACAAGCCCGGCGCGTTGCAATTGAGGCTCGACACACGAC
CCGATCACCTCGCCTATCTC

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MKMKNPKTGPKIVVVGAGAFGTALAAVAADKANVTLLARREEAAEECRRTGRNEAALPGIPLPAGLSYSSQAAALGDAHI
VLFAMPSQAHRDAARRYGDAIGAKAIVVTCAKGMEQSTGRLLTDVLDEELPGRRIGVLSGPGFAADIAKGLPTAMVIAAP
DRAIATELAEVLSGRTFRLYPSADRTGVQLGGALKNVLAIACGIVEGAGLGDSARAALISRGLAEMSRFIVARGGDADTV
RGLSGLGDLVLTATSHQSRNLRFGITLGKSGRAEGSGELVEGAFAASVAARVAGELGIDMPITEAVAAIVDGKLDVRSAL
EQLMSRPITHE

Sequences:

>Translated_331_residues
MKMKNPKTGPKIVVVGAGAFGTALAAVAADKANVTLLARREEAAEECRRTGRNEAALPGIPLPAGLSYSSQAAALGDAHI
VLFAMPSQAHRDAARRYGDAIGAKAIVVTCAKGMEQSTGRLLTDVLDEELPGRRIGVLSGPGFAADIAKGLPTAMVIAAP
DRAIATELAEVLSGRTFRLYPSADRTGVQLGGALKNVLAIACGIVEGAGLGDSARAALISRGLAEMSRFIVARGGDADTV
RGLSGLGDLVLTATSHQSRNLRFGITLGKSGRAEGSGELVEGAFAASVAARVAGELGIDMPITEAVAAIVDGKLDVRSAL
EQLMSRPITHE
>Mature_331_residues
MKMKNPKTGPKIVVVGAGAFGTALAAVAADKANVTLLARREEAAEECRRTGRNEAALPGIPLPAGLSYSSQAAALGDAHI
VLFAMPSQAHRDAARRYGDAIGAKAIVVTCAKGMEQSTGRLLTDVLDEELPGRRIGVLSGPGFAADIAKGLPTAMVIAAP
DRAIATELAEVLSGRTFRLYPSADRTGVQLGGALKNVLAIACGIVEGAGLGDSARAALISRGLAEMSRFIVARGGDADTV
RGLSGLGDLVLTATSHQSRNLRFGITLGKSGRAEGSGELVEGAFAASVAARVAGELGIDMPITEAVAAIVDGKLDVRSAL
EQLMSRPITHE

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI24307999, Length=343, Percent_Identity=25.9475218658892, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI33695088, Length=280, Percent_Identity=26.7857142857143, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI1790037, Length=326, Percent_Identity=40.7975460122699, Blast_Score=211, Evalue=6e-56,
Organism=Caenorhabditis elegans, GI32564399, Length=346, Percent_Identity=24.5664739884393, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17507425, Length=276, Percent_Identity=25.7246376811594, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193210136, Length=355, Percent_Identity=23.943661971831, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI32564403, Length=355, Percent_Identity=23.943661971831, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI193210134, Length=220, Percent_Identity=27.7272727272727, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324513, Length=354, Percent_Identity=26.8361581920904, Blast_Score=100, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6320181, Length=346, Percent_Identity=26.878612716763, Blast_Score=95, Evalue=1e-20,
Organism=Drosophila melanogaster, GI17136200, Length=345, Percent_Identity=24.6376811594203, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17136202, Length=345, Percent_Identity=24.6376811594203, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17136204, Length=345, Percent_Identity=24.6376811594203, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI45551945, Length=278, Percent_Identity=25.5395683453237, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281362270, Length=278, Percent_Identity=25.5395683453237, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24648969, Length=224, Percent_Identity=25.8928571428571, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 33854; Mature: 33854

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMKNPKTGPKIVVVGAGAFGTALAAVAADKANVTLLARREEAAEECRRTGRNEAALPGI
CCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHCCCCCCCCCCC
PLPAGLSYSSQAAALGDAHIVLFAMPSQAHRDAARRYGDAIGAKAIVVTCAKGMEQSTGR
CCCCCCCCCCCHHHCCCCEEEEEECCCHHHHHHHHHHHHHHCCHHHEEEHHHCCCHHHHH
LLTDVLDEELPGRRIGVLSGPGFAADIAKGLPTAMVIAAPDRAIATELAEVLSGRTFRLY
HHHHHHHHCCCCCEEEEECCCCHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCEEEEE
PSADRTGVQLGGALKNVLAIACGIVEGAGLGDSARAALISRGLAEMSRFIVARGGDADTV
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCHHHH
RGLSGLGDLVLTATSHQSRNLRFGITLGKSGRAEGSGELVEGAFAASVAARVAGELGIDM
HHHHCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
PITEAVAAIVDGKLDVRSALEQLMSRPITHE
CHHHHHHHHHCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKMKNPKTGPKIVVVGAGAFGTALAAVAADKANVTLLARREEAAEECRRTGRNEAALPGI
CCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHCCCCCCCCCCC
PLPAGLSYSSQAAALGDAHIVLFAMPSQAHRDAARRYGDAIGAKAIVVTCAKGMEQSTGR
CCCCCCCCCCCHHHCCCCEEEEEECCCHHHHHHHHHHHHHHCCHHHEEEHHHCCCHHHHH
LLTDVLDEELPGRRIGVLSGPGFAADIAKGLPTAMVIAAPDRAIATELAEVLSGRTFRLY
HHHHHHHHCCCCCEEEEECCCCHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCEEEEE
PSADRTGVQLGGALKNVLAIACGIVEGAGLGDSARAALISRGLAEMSRFIVARGGDADTV
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCHHHH
RGLSGLGDLVLTATSHQSRNLRFGITLGKSGRAEGSGELVEGAFAASVAARVAGELGIDM
HHHHCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
PITEAVAAIVDGKLDVRSALEQLMSRPITHE
CHHHHHHHHHCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]