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The map label for this gene is sucD [H]

Identifier: 150398139

GI number: 150398139

Start: 3090374

End: 3091276

Strand: Reverse

Name: sucD [H]

Synonym: Smed_2942

Alternate gene names: 150398139

Gene position: 3091276-3090374 (Counterclockwise)

Preceding gene: 150398140

Following gene: 150398138

Centisome position: 81.74

GC content: 63.9

Gene sequence:

>903_bases
ATGTCCATCCTGATCAACAAAGACACCAAGGTTCTCGTTCAGGGCCTGACCGGCAAGACCGGCACCTTTCACACCGAACA
GGCGCTCGCCTATAACGGCACCAAGATGGTCGGCGGCATTCACCCGAAAAAGGGCGGCGAGACCTGGACCGGCGCCAAGG
GCGAGCAGCTGCCGATCTTCGCGACGGTCGCCGAGGGCCGCGACGCCACCGGCGCCGATGCTTCCGTGATCTATGTTCCG
CCGGCCGGTGCCGCCGCGGCGATAATCGAGGCGATTGACGCCGAAATCCCGCTCATCGTCTGCATCACCGAGGGAATTCC
GGTCGCCGATATGGTGAAGGTCAAGGCGCGGCTCGATAAATCGTCTTCGCGCCTCATCGGCCCGAACTGCCCGGGCGTTC
TCACGCCCGACGAGTGCAAGATCGGCATCATGCCGGGCAATATCTTCCGCAAGGGCTCGGTCGGGGTGCTTTCGCGCTCC
GGTACGCTTACCTACGAAGCGGTGTTCCAGACGACCAATGAGGGCCTCGGCCAGACGACGGCAGTGGGCATCGGCGGCGA
CCCGGTCAAGGGCACCGAATTCATCGACGTCCTGGAAATGTTCCTCGCGGACGACGAGACCAAATCGATCATCATGATCG
GCGAGATCGGTGGTTCGGCGGAAGAGGAAGCGGCTCAGTTCCTGAAGGATGAAGCAAAGCGCGGCCGCAAGAAGCCGATG
GTCGGCTTCATCGCAGGCCGCACGGCGCCTCCCGGCCGCACCATGGGCCATGCCGGTGCCGTCATTTCGGGCGGCAAGGG
CGGTGCGGAAGACAAGATCGCGGCGATGGAATCGGCGGGAATCCGCGTTTCGCCATCGCCGGCACGCCTCGGCAAGACGC
TGGTCGAAGTCCTGAAGGGCTGA

Upstream 100 bases:

>100_bases
GAAGATCATCAATGAATCGGGCCTCAACGTGATTTCCGCCGATGATCTGGACGATGCCGCCCAGAAGATCGTTGCAGCCG
TCAAGGGAGCCTGAGGTTTC

Downstream 100 bases:

>100_bases
CGAACTCTTCCCGCAGCGCCCGGGCGTCCCGTCGGACGCGTACAGGGCGCTGCGGGACCTTACAGCGGGGCGGCAGGGCA
TGCCGCCCCATTGGAGCCAA

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MSILINKDTKVLVQGLTGKTGTFHTEQALAYNGTKMVGGIHPKKGGETWTGAKGEQLPIFATVAEGRDATGADASVIYVP
PAGAAAAIIEAIDAEIPLIVCITEGIPVADMVKVKARLDKSSSRLIGPNCPGVLTPDECKIGIMPGNIFRKGSVGVLSRS
GTLTYEAVFQTTNEGLGQTTAVGIGGDPVKGTEFIDVLEMFLADDETKSIIMIGEIGGSAEEEAAQFLKDEAKRGRKKPM
VGFIAGRTAPPGRTMGHAGAVISGGKGGAEDKIAAMESAGIRVSPSPARLGKTLVEVLKG

Sequences:

>Translated_300_residues
MSILINKDTKVLVQGLTGKTGTFHTEQALAYNGTKMVGGIHPKKGGETWTGAKGEQLPIFATVAEGRDATGADASVIYVP
PAGAAAAIIEAIDAEIPLIVCITEGIPVADMVKVKARLDKSSSRLIGPNCPGVLTPDECKIGIMPGNIFRKGSVGVLSRS
GTLTYEAVFQTTNEGLGQTTAVGIGGDPVKGTEFIDVLEMFLADDETKSIIMIGEIGGSAEEEAAQFLKDEAKRGRKKPM
VGFIAGRTAPPGRTMGHAGAVISGGKGGAEDKIAAMESAGIRVSPSPARLGKTLVEVLKG
>Mature_299_residues
SILINKDTKVLVQGLTGKTGTFHTEQALAYNGTKMVGGIHPKKGGETWTGAKGEQLPIFATVAEGRDATGADASVIYVPP
AGAAAAIIEAIDAEIPLIVCITEGIPVADMVKVKARLDKSSSRLIGPNCPGVLTPDECKIGIMPGNIFRKGSVGVLSRSG
TLTYEAVFQTTNEGLGQTTAVGIGGDPVKGTEFIDVLEMFLADDETKSIIMIGEIGGSAEEEAAQFLKDEAKRGRKKPMV
GFIAGRTAPPGRTMGHAGAVISGGKGGAEDKIAAMESAGIRVSPSPARLGKTLVEVLKG

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=295, Percent_Identity=63.728813559322, Blast_Score=310, Evalue=1e-84,
Organism=Homo sapiens, GI38569423, Length=319, Percent_Identity=27.2727272727273, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI38569421, Length=319, Percent_Identity=27.2727272727273, Blast_Score=88, Evalue=9e-18,
Organism=Escherichia coli, GI1786949, Length=299, Percent_Identity=61.2040133779264, Blast_Score=350, Evalue=5e-98,
Organism=Caenorhabditis elegans, GI17550194, Length=300, Percent_Identity=62, Blast_Score=354, Evalue=3e-98,
Organism=Caenorhabditis elegans, GI17553126, Length=300, Percent_Identity=62, Blast_Score=349, Evalue=1e-96,
Organism=Caenorhabditis elegans, GI17557344, Length=322, Percent_Identity=27.639751552795, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17551266, Length=313, Percent_Identity=27.4760383386581, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324716, Length=300, Percent_Identity=51, Blast_Score=280, Evalue=2e-76,
Organism=Drosophila melanogaster, GI21356559, Length=296, Percent_Identity=60.1351351351351, Blast_Score=360, Evalue=1e-100,
Organism=Drosophila melanogaster, GI28574296, Length=299, Percent_Identity=63.8795986622074, Blast_Score=336, Evalue=1e-92,
Organism=Drosophila melanogaster, GI281363477, Length=280, Percent_Identity=28.2142857142857, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI281363475, Length=280, Percent_Identity=28.2142857142857, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI281363473, Length=280, Percent_Identity=28.2142857142857, Blast_Score=88, Evalue=7e-18,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30915; Mature: 30784

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILINKDTKVLVQGLTGKTGTFHTEQALAYNGTKMVGGIHPKKGGETWTGAKGEQLPIF
CEEEEECCCEEEEEECCCCCCCEECCCCEEECCCEEECCCCCCCCCCCCCCCCCCCCEEE
ATVAEGRDATGADASVIYVPPAGAAAAIIEAIDAEIPLIVCITEGIPVADMVKVKARLDK
EEEECCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCC
SSSRLIGPNCPGVLTPDECKIGIMPGNIFRKGSVGVLSRSGTLTYEAVFQTTNEGLGQTT
CCCCEECCCCCCCCCCCCCEEEEECCCEEECCCCEEEECCCCEEEEEEEEHHCCCCCCEE
AVGIGGDPVKGTEFIDVLEMFLADDETKSIIMIGEIGGSAEEEAAQFLKDEAKRGRKKPM
EEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCC
VGFIAGRTAPPGRTMGHAGAVISGGKGGAEDKIAAMESAGIRVSPSPARLGKTLVEVLKG
EEEEECCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHCCCEEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SILINKDTKVLVQGLTGKTGTFHTEQALAYNGTKMVGGIHPKKGGETWTGAKGEQLPIF
EEEEECCCEEEEEECCCCCCCEECCCCEEECCCEEECCCCCCCCCCCCCCCCCCCCEEE
ATVAEGRDATGADASVIYVPPAGAAAAIIEAIDAEIPLIVCITEGIPVADMVKVKARLDK
EEEECCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCC
SSSRLIGPNCPGVLTPDECKIGIMPGNIFRKGSVGVLSRSGTLTYEAVFQTTNEGLGQTT
CCCCEECCCCCCCCCCCCCEEEEECCCEEECCCCEEEECCCCEEEEEEEEHHCCCCCCEE
AVGIGGDPVKGTEFIDVLEMFLADDETKSIIMIGEIGGSAEEEAAQFLKDEAKRGRKKPM
EEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCC
VGFIAGRTAPPGRTMGHAGAVISGGKGGAEDKIAAMESAGIRVSPSPARLGKTLVEVLKG
EEEEECCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHCCCEEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]