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The map label for this gene is ygfU [H]

Identifier: 150398108

GI number: 150398108

Start: 3055977

End: 3057461

Strand: Direct

Name: ygfU [H]

Synonym: Smed_2911

Alternate gene names: 150398108

Gene position: 3055977-3057461 (Clockwise)

Preceding gene: 150398107

Following gene: 150398109

Centisome position: 80.81

GC content: 62.76

Gene sequence:

>1485_bases
ATGAACGACGCATCCAGCATACATCCCGTGGACGAGCGCCTGCCGGTCGGCAGGCTTGCAACGCTCGGGATACAGCATGT
TCTTGTCATGTATGGCGGCGCGGTCGCCGTTCCGCTGATCGTCGGACGGGCGCTGCAACTGAGCCCGGAAGACGTCGCCT
TCCTGATTTCGGCGGATCTCTTCGTCTGCGGCATCGTCACCATCATCCAGTCGCTCGGACTGACGAGAGGCATAGGCATT
CGCCTCCCCGTGATGATGGGCGTCACCTTTGCCGCCGTCGGCCCCATGGTCTCCATGGCGGCCATGACACCGGGGATCGA
CGGGGCCAGAACGATCTTCGGCGCGATCATCGGTGCAGGGCTCGTTGCGCTTCTGCTCGCGCCCGTCATGGGGCGCCTTT
TGAAGTTCTTCCCGCCCGTTGTCACCGGCACGATCATTCTCGTCATCGGGGTGACCCTGATGCGCGTCGGCGTCAATTGG
ATATTCGGCAATCCCTTCGGCCCGACCGCGCCGAAACTCGTGGATCCGGCCCATGCGCAATGGCTGGCGGAATTGAAACA
GCTCGCCACGGCAGGCGGATCTGCCGTGCCGGACGGGCTCGTCCTCGGTGCGACGATACCGAACCCGATCTATGCCGAAC
CGAGCCATGTGGCGCTTGCCGCCTTCGTTCTGGTCTCCATTCTCGTTGTGGCGCGCTTCGGCAAGGGTCTCATCAGCAAC
ATCGCTGTTCTGATCGGCATCGCGGTCGGATGCGTAGCGGCGGCTATGCTCGGCATGATGCACTTCGATCGTGTGGCGAG
CGCCGGCTGGTTCGCCGTCGTGACGCCCCTGCGCTTCGGCACGCCCATTTTCGATCCGGTGCTGATTGCCACGATGTCGC
TCGTCATGGTCGTGGTGATGATCGAATCGACCGGCATGTTCCTGGCGCTCGGCGAGATGACCAATCGTGAAGTGACGCAG
CAGCAACTGACCGCCGGGCTGCGCGTGGACGGCCTTGGCACCGTTATCGGCGGCCTCTTCAACACCTTTCCCTATACGAG
CTTCTCGCAGAATGTGGGGCTCGTCGGCGTCACCGGCGTCAAGAGCCGTTACGTGTGCGTCATGGGCGGCATCATCATGA
TCCTGCTCGGACTCGTTCCCAAGATGGGCGCGCTGGTCGAGGCCGTTCCGACATTCGTTCTCGGGGGAGCCGGGCTCGTA
ATGTTCGGCATGGTGGCGGCAACTGGTGTCAGGATTCTCTCCACGGTCGACTTCAAGTCCTCGCGCAACAACCTGTTCGT
CGTGGCCGTTTCCGTCGGATTCGGGTTGATCCCGATGATTGCTCCGAACTTCCTGATGTGGATGGCGCATGCGCTCCACC
CGATCATCGAGTCCGGCATCGTCCTCGCGGCCATCTCGGCCATCGTGCTCAACGCCTTCTTCAACGGCCTCAGTCTCGAG
CGTTCCGCTTGCGTCGAGGCCGCGCGGATGGCAGACGGGCATTGA

Upstream 100 bases:

>100_bases
AAAACCGGAAAGTGTTTCCGATTCTCCCTCCCTTGCGACATGCGCCCGCCGCACGAAAAGTCTCCGTTCCCGTTGGAGGA
CGGGGAATGGAGGAGGAACC

Downstream 100 bases:

>100_bases
TCAAAGGACAATCTCCCGTGGCCCAGGGCCACGGGAGATTGTCACACTTCGATCGGCACCGAAGCATTGCGGCAGCTCCG
GGCGGTAGGAATGGTCCGAT

Product: uracil-xanthine permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 494; Mature: 494

Protein sequence:

>494_residues
MNDASSIHPVDERLPVGRLATLGIQHVLVMYGGAVAVPLIVGRALQLSPEDVAFLISADLFVCGIVTIIQSLGLTRGIGI
RLPVMMGVTFAAVGPMVSMAAMTPGIDGARTIFGAIIGAGLVALLLAPVMGRLLKFFPPVVTGTIILVIGVTLMRVGVNW
IFGNPFGPTAPKLVDPAHAQWLAELKQLATAGGSAVPDGLVLGATIPNPIYAEPSHVALAAFVLVSILVVARFGKGLISN
IAVLIGIAVGCVAAAMLGMMHFDRVASAGWFAVVTPLRFGTPIFDPVLIATMSLVMVVVMIESTGMFLALGEMTNREVTQ
QQLTAGLRVDGLGTVIGGLFNTFPYTSFSQNVGLVGVTGVKSRYVCVMGGIIMILLGLVPKMGALVEAVPTFVLGGAGLV
MFGMVAATGVRILSTVDFKSSRNNLFVVAVSVGFGLIPMIAPNFLMWMAHALHPIIESGIVLAAISAIVLNAFFNGLSLE
RSACVEAARMADGH

Sequences:

>Translated_494_residues
MNDASSIHPVDERLPVGRLATLGIQHVLVMYGGAVAVPLIVGRALQLSPEDVAFLISADLFVCGIVTIIQSLGLTRGIGI
RLPVMMGVTFAAVGPMVSMAAMTPGIDGARTIFGAIIGAGLVALLLAPVMGRLLKFFPPVVTGTIILVIGVTLMRVGVNW
IFGNPFGPTAPKLVDPAHAQWLAELKQLATAGGSAVPDGLVLGATIPNPIYAEPSHVALAAFVLVSILVVARFGKGLISN
IAVLIGIAVGCVAAAMLGMMHFDRVASAGWFAVVTPLRFGTPIFDPVLIATMSLVMVVVMIESTGMFLALGEMTNREVTQ
QQLTAGLRVDGLGTVIGGLFNTFPYTSFSQNVGLVGVTGVKSRYVCVMGGIIMILLGLVPKMGALVEAVPTFVLGGAGLV
MFGMVAATGVRILSTVDFKSSRNNLFVVAVSVGFGLIPMIAPNFLMWMAHALHPIIESGIVLAAISAIVLNAFFNGLSLE
RSACVEAARMADGH
>Mature_494_residues
MNDASSIHPVDERLPVGRLATLGIQHVLVMYGGAVAVPLIVGRALQLSPEDVAFLISADLFVCGIVTIIQSLGLTRGIGI
RLPVMMGVTFAAVGPMVSMAAMTPGIDGARTIFGAIIGAGLVALLLAPVMGRLLKFFPPVVTGTIILVIGVTLMRVGVNW
IFGNPFGPTAPKLVDPAHAQWLAELKQLATAGGSAVPDGLVLGATIPNPIYAEPSHVALAAFVLVSILVVARFGKGLISN
IAVLIGIAVGCVAAAMLGMMHFDRVASAGWFAVVTPLRFGTPIFDPVLIATMSLVMVVVMIESTGMFLALGEMTNREVTQ
QQLTAGLRVDGLGTVIGGLFNTFPYTSFSQNVGLVGVTGVKSRYVCVMGGIIMILLGLVPKMGALVEAVPTFVLGGAGLV
MFGMVAATGVRILSTVDFKSSRNNLFVVAVSVGFGLIPMIAPNFLMWMAHALHPIIESGIVLAAISAIVLNAFFNGLSLE
RSACVEAARMADGH

Specific function: Unknown

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680148, Length=172, Percent_Identity=36.046511627907, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI40316845, Length=172, Percent_Identity=36.046511627907, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI44680143, Length=185, Percent_Identity=34.5945945945946, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI44680145, Length=185, Percent_Identity=34.5945945945946, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI87082181, Length=483, Percent_Identity=48.6542443064182, Blast_Score=439, Evalue=1e-124,
Organism=Escherichia coli, GI1790087, Length=484, Percent_Identity=28.7190082644628, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI87081818, Length=480, Percent_Identity=28.3333333333333, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI87082178, Length=486, Percent_Identity=27.1604938271605, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788843, Length=422, Percent_Identity=27.0142180094787, Blast_Score=109, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17558856, Length=228, Percent_Identity=29.3859649122807, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17542262, Length=440, Percent_Identity=24.0909090909091, Blast_Score=82, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17541904, Length=464, Percent_Identity=23.2758620689655, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71993493, Length=445, Percent_Identity=22.0224719101124, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17542260, Length=168, Percent_Identity=26.7857142857143, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21356175, Length=477, Percent_Identity=25.7861635220126, Blast_Score=111, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 51261; Mature: 51261

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDASSIHPVDERLPVGRLATLGIQHVLVMYGGAVAVPLIVGRALQLSPEDVAFLISADL
CCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHH
FVCGIVTIIQSLGLTRGIGIRLPVMMGVTFAAVGPMVSMAAMTPGIDGARTIFGAIIGAG
HHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LVALLLAPVMGRLLKFFPPVVTGTIILVIGVTLMRVGVNWIFGNPFGPTAPKLVDPAHAQ
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHEECCCCCCCCCCCCCHHHHH
WLAELKQLATAGGSAVPDGLVLGATIPNPIYAEPSHVALAAFVLVSILVVARFGKGLISN
HHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHH
IAVLIGIAVGCVAAAMLGMMHFDRVASAGWFAVVTPLRFGTPIFDPVLIATMSLVMVVVM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEECCHHCCCCHHHHHHHHHHHHHHHHHH
IESTGMFLALGEMTNREVTQQQLTAGLRVDGLGTVIGGLFNTFPYTSFSQNVGLVGVTGV
HHCCCCEEEECCHHCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCC
KSRYVCVMGGIIMILLGLVPKMGALVEAVPTFVLGGAGLVMFGMVAATGVRILSTVDFKS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEECCCC
SRNNLFVVAVSVGFGLIPMIAPNFLMWMAHALHPIIESGIVLAAISAIVLNAFFNGLSLE
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCC
RSACVEAARMADGH
HHHHHHHHHHCCCC
>Mature Secondary Structure
MNDASSIHPVDERLPVGRLATLGIQHVLVMYGGAVAVPLIVGRALQLSPEDVAFLISADL
CCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHH
FVCGIVTIIQSLGLTRGIGIRLPVMMGVTFAAVGPMVSMAAMTPGIDGARTIFGAIIGAG
HHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LVALLLAPVMGRLLKFFPPVVTGTIILVIGVTLMRVGVNWIFGNPFGPTAPKLVDPAHAQ
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHEECCCCCCCCCCCCCHHHHH
WLAELKQLATAGGSAVPDGLVLGATIPNPIYAEPSHVALAAFVLVSILVVARFGKGLISN
HHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHH
IAVLIGIAVGCVAAAMLGMMHFDRVASAGWFAVVTPLRFGTPIFDPVLIATMSLVMVVVM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEECCHHCCCCHHHHHHHHHHHHHHHHHH
IESTGMFLALGEMTNREVTQQQLTAGLRVDGLGTVIGGLFNTFPYTSFSQNVGLVGVTGV
HHCCCCEEEECCHHCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCC
KSRYVCVMGGIIMILLGLVPKMGALVEAVPTFVLGGAGLVMFGMVAATGVRILSTVDFKS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEECCCC
SRNNLFVVAVSVGFGLIPMIAPNFLMWMAHALHPIIESGIVLAAISAIVLNAFFNGLSLE
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCC
RSACVEAARMADGH
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]