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The map label for this gene is arcB [H]

Identifier: 150398089

GI number: 150398089

Start: 3032444

End: 3033367

Strand: Direct

Name: arcB [H]

Synonym: Smed_2891

Alternate gene names: 150398089

Gene position: 3032444-3033367 (Clockwise)

Preceding gene: 150398086

Following gene: 150398090

Centisome position: 80.18

GC content: 64.07

Gene sequence:

>924_bases
ATGAAAACCATCACATTGATCGGCGCACCCATAGAGGAAGGCTCCGGCCGCCGCGGCGCAGGCATGGGGCCGACGGCGCT
CAGGATAGCAGGCATAGACACCGTCCTTGCGGAACTGGGCCATACGGTCACCGACGAGGGGGACCTGAAGCCGGTTCCGG
CGCGAGACCTCGCCAAACATCCGGGCGCCAACAATCTGCAGACCGTTGCGGCTTTCGCCCGGGCGCTCGACGAAGCCGTG
CATGACACCGCGCGCAAGGGAAATATCCCCATCATTCTCGGCGGCGACCACGCCCTTTCGATGGGTAGCGTTTCCGGCAT
GGCGCGGCATGCTCATGAGGTCGGACGGCCCCTCTTCGTCCTGTGGCTCGATGCGCATGCCGACTTCAATTCGCCGGTGA
CCTCGCCCTCGGGGAATATGCACGGCATGCCCGTCGCCTTCTTTTGCGGCGAAGCGGAGTTCGCTCCGATCCTTCCGAGA
GACCGGCCGCTGGTCGATCCGAAGAGGGTTTACCAGGTCGGGATCCGTTCGGTGGATGCCCGCGAGCGCGAGGAGATCGC
AGAGCACGGCGTCAATGTCTTCGATATGCGCACCATCGACGAGATGGGCATGGCTCATATTATCCGCCAGATCGTCGACG
AGGTACGGGCTGCCAACGGCCTCCTGCATGTCAGCCTCGACGTGGATTTCATGGATCCGGAGCTTGCCCCTGGCGTCGGC
ACGACGGTCCCTGGCGGTGCGACGTTTCGCGAGGCACATCTTATCATGGAGGTGCTATGCGACAGCGGCCTCGTTTCGTC
GCTCGACGTGGTCGAGCTCAATCCGTTTCTCGACGACCGGGGAAAAAGCGCGCGCATCCTGGTCGAACTGACCGCAAGCC
TCTTCGGCCGCCGCATCCTGGACCGCCCGACCCGCGCCGCCTGA

Upstream 100 bases:

>100_bases
CGGCAGTTTTCCATCTTTTTGCCGACACGCTTTTTGACGATAATCTGCCGGGTTTTACGGGGCTCCGGACTCACAAGACC
AGCAAAGGGAAGATGCGGAC

Downstream 100 bases:

>100_bases
TGCTGATGCTCGGCTCGGCTCCGCTCCAACGGGACGACCATCTTCAGCAAAAGCTTAACGAATCCGCGCTTAGAATAGGC
ATACAGAGCGCAAAGCGGAT

Product: arginase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MKTITLIGAPIEEGSGRRGAGMGPTALRIAGIDTVLAELGHTVTDEGDLKPVPARDLAKHPGANNLQTVAAFARALDEAV
HDTARKGNIPIILGGDHALSMGSVSGMARHAHEVGRPLFVLWLDAHADFNSPVTSPSGNMHGMPVAFFCGEAEFAPILPR
DRPLVDPKRVYQVGIRSVDAREREEIAEHGVNVFDMRTIDEMGMAHIIRQIVDEVRAANGLLHVSLDVDFMDPELAPGVG
TTVPGGATFREAHLIMEVLCDSGLVSSLDVVELNPFLDDRGKSARILVELTASLFGRRILDRPTRAA

Sequences:

>Translated_307_residues
MKTITLIGAPIEEGSGRRGAGMGPTALRIAGIDTVLAELGHTVTDEGDLKPVPARDLAKHPGANNLQTVAAFARALDEAV
HDTARKGNIPIILGGDHALSMGSVSGMARHAHEVGRPLFVLWLDAHADFNSPVTSPSGNMHGMPVAFFCGEAEFAPILPR
DRPLVDPKRVYQVGIRSVDAREREEIAEHGVNVFDMRTIDEMGMAHIIRQIVDEVRAANGLLHVSLDVDFMDPELAPGVG
TTVPGGATFREAHLIMEVLCDSGLVSSLDVVELNPFLDDRGKSARILVELTASLFGRRILDRPTRAA
>Mature_307_residues
MKTITLIGAPIEEGSGRRGAGMGPTALRIAGIDTVLAELGHTVTDEGDLKPVPARDLAKHPGANNLQTVAAFARALDEAV
HDTARKGNIPIILGGDHALSMGSVSGMARHAHEVGRPLFVLWLDAHADFNSPVTSPSGNMHGMPVAFFCGEAEFAPILPR
DRPLVDPKRVYQVGIRSVDAREREEIAEHGVNVFDMRTIDEMGMAHIIRQIVDEVRAANGLLHVSLDVDFMDPELAPGVG
TTVPGGATFREAHLIMEVLCDSGLVSSLDVVELNPFLDDRGKSARILVELTASLFGRRILDRPTRAA

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI4502215, Length=312, Percent_Identity=37.1794871794872, Blast_Score=191, Evalue=5e-49,
Organism=Homo sapiens, GI10947139, Length=304, Percent_Identity=34.2105263157895, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI37537722, Length=299, Percent_Identity=28.4280936454849, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI1789306, Length=284, Percent_Identity=27.112676056338, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71996843, Length=230, Percent_Identity=29.1304347826087, Blast_Score=95, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6325146, Length=304, Percent_Identity=30.2631578947368, Blast_Score=143, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24638886, Length=319, Percent_Identity=33.8557993730408, Blast_Score=152, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014033
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.1 [H]

Molecular weight: Translated: 32901; Mature: 32901

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTITLIGAPIEEGSGRRGAGMGPTALRIAGIDTVLAELGHTVTDEGDLKPVPARDLAKH
CCEEEEEECCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHC
PGANNLQTVAAFARALDEAVHDTARKGNIPIILGGDHALSMGSVSGMARHAHEVGRPLFV
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHHHCCCEEE
LWLDAHADFNSPVTSPSGNMHGMPVAFFCGEAEFAPILPRDRPLVDPKRVYQVGIRSVDA
EEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCH
REREEIAEHGVNVFDMRTIDEMGMAHIIRQIVDEVRAANGLLHVSLDVDFMDPELAPGVG
HHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCCCCCCC
TTVPGGATFREAHLIMEVLCDSGLVSSLDVVELNPFLDDRGKSARILVELTASLFGRRIL
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCEEHEEEHHHHHHHHHH
DRPTRAA
CCCCCCC
>Mature Secondary Structure
MKTITLIGAPIEEGSGRRGAGMGPTALRIAGIDTVLAELGHTVTDEGDLKPVPARDLAKH
CCEEEEEECCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHC
PGANNLQTVAAFARALDEAVHDTARKGNIPIILGGDHALSMGSVSGMARHAHEVGRPLFV
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHHHCCCEEE
LWLDAHADFNSPVTSPSGNMHGMPVAFFCGEAEFAPILPRDRPLVDPKRVYQVGIRSVDA
EEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCH
REREEIAEHGVNVFDMRTIDEMGMAHIIRQIVDEVRAANGLLHVSLDVDFMDPELAPGVG
HHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCCCCCCC
TTVPGGATFREAHLIMEVLCDSGLVSSLDVVELNPFLDDRGKSARILVELTASLFGRRIL
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCEEHEEEHHHHHHHHHH
DRPTRAA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9375792 [H]