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The map label for this gene is yafC [H]

Identifier: 150398061

GI number: 150398061

Start: 2995617

End: 2996564

Strand: Reverse

Name: yafC [H]

Synonym: Smed_2863

Alternate gene names: 150398061

Gene position: 2996564-2995617 (Counterclockwise)

Preceding gene: 150398068

Following gene: 150398060

Centisome position: 79.23

GC content: 61.39

Gene sequence:

>948_bases
ATGAATCCGAATTTTACCTGGGACGACCTGCAGTTCTTCCTCGCCGTCGCGCGGACGGGGCAGCTTTCGACCGCGGCGCG
GCGCCTGAGGACGAGTCACGCGACGGTGTCGCGCCGTATCGACCGGCTCGAATTCGCACTCAAAGTAAAGCTATTCGAGC
GCAATCCGCGCGGGTATGTGCTGACCACGATGGGGCAGCGGTTTGTCGAGACAGCTGAGCGGATCGAGCGGGAGACCGAG
CAATTGCAGCTCGACATCAGTGACGGCATGACGGCGCAACGCGGCGTTGTTCGGCTGAGCACGCTCGAAGGCTTCGGCAA
CTTCTTCCTTGCGGACCGGCTATCGGACTTTGTGGGCCGCTATCCCAACATCTCGCTCGAACTGGTGGCGATCCAGCAGA
TCATGTCGCTGTCGCGCAAGGAGGCCGATGTCGCGGTAGCGCTCGCCGCACCGAAAGCAGGGCCTTACCATTCGGAAGTG
CTGACACCCTATACGCTGCATGTCTATGGCGCACGCAGCTATCTCGCGGGTCATCCGCTGATCCGTACACGCAACGATCT
CGGTTCGCACCGCTTCGCCGGCTATATCGACGACATGATCTTCACGCCGGGGCTCGACTATCTCGGTGAATTACAGCCCG
GGCTCCGGGCCCATTTCCAAAGCTCGAGCATTCTCACCCAGTTGAAGGCGGTGCGACAGGGATTGGGGCTCTGCGTCCTC
CCGCACTTCATGGCCAAGGATGAGCCTGATCTCGAAATCGTGTTGCCGGACGAGATCGCACTCCAGCGGACCTATTGGCT
GATCTGCCACCGCGACCTGATCGGGATGCCCCGGGTGAAGGCCCTGCGCGATTTCCTTGTCGATTCCGTTGCCGCGAACC
GGGGCTGCTTCCTGCGTGAAATCCTGTCCGCTCCGGCGGGTTCACGTCGGGCCCTTGAACATCAATAG

Upstream 100 bases:

>100_bases
GCCGAGTATTTACCATCCAGAAAATTTTGCTTGGAAGCAAGGCGGGTGCCCCGTAAATTGCAAACAGCATCTGTTCATTT
TTGAACAGGAAGGGAGGGGC

Downstream 100 bases:

>100_bases
GTCGTTAACCATATAGGACCGGCAGGCACGGACTTTCCTGGGCGCGAGCGCTCAAAAAAACGATCGCCACTCTGCCCGGT
TTCGGATCAGTTCGCGGCCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MNPNFTWDDLQFFLAVARTGQLSTAARRLRTSHATVSRRIDRLEFALKVKLFERNPRGYVLTTMGQRFVETAERIERETE
QLQLDISDGMTAQRGVVRLSTLEGFGNFFLADRLSDFVGRYPNISLELVAIQQIMSLSRKEADVAVALAAPKAGPYHSEV
LTPYTLHVYGARSYLAGHPLIRTRNDLGSHRFAGYIDDMIFTPGLDYLGELQPGLRAHFQSSSILTQLKAVRQGLGLCVL
PHFMAKDEPDLEIVLPDEIALQRTYWLICHRDLIGMPRVKALRDFLVDSVAANRGCFLREILSAPAGSRRALEHQ

Sequences:

>Translated_315_residues
MNPNFTWDDLQFFLAVARTGQLSTAARRLRTSHATVSRRIDRLEFALKVKLFERNPRGYVLTTMGQRFVETAERIERETE
QLQLDISDGMTAQRGVVRLSTLEGFGNFFLADRLSDFVGRYPNISLELVAIQQIMSLSRKEADVAVALAAPKAGPYHSEV
LTPYTLHVYGARSYLAGHPLIRTRNDLGSHRFAGYIDDMIFTPGLDYLGELQPGLRAHFQSSSILTQLKAVRQGLGLCVL
PHFMAKDEPDLEIVLPDEIALQRTYWLICHRDLIGMPRVKALRDFLVDSVAANRGCFLREILSAPAGSRRALEHQ
>Mature_315_residues
MNPNFTWDDLQFFLAVARTGQLSTAARRLRTSHATVSRRIDRLEFALKVKLFERNPRGYVLTTMGQRFVETAERIERETE
QLQLDISDGMTAQRGVVRLSTLEGFGNFFLADRLSDFVGRYPNISLELVAIQQIMSLSRKEADVAVALAAPKAGPYHSEV
LTPYTLHVYGARSYLAGHPLIRTRNDLGSHRFAGYIDDMIFTPGLDYLGELQPGLRAHFQSSSILTQLKAVRQGLGLCVL
PHFMAKDEPDLEIVLPDEIALQRTYWLICHRDLIGMPRVKALRDFLVDSVAANRGCFLREILSAPAGSRRALEHQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=308, Percent_Identity=25.3246753246753, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI157672245, Length=152, Percent_Identity=34.2105263157895, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789173, Length=302, Percent_Identity=26.158940397351, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789440, Length=288, Percent_Identity=25.3472222222222, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786448, Length=246, Percent_Identity=27.2357723577236, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789639, Length=292, Percent_Identity=23.6301369863014, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1789204, Length=248, Percent_Identity=27.4193548387097, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI87081978, Length=139, Percent_Identity=30.9352517985612, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787128, Length=253, Percent_Identity=24.901185770751, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35513; Mature: 35513

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPNFTWDDLQFFLAVARTGQLSTAARRLRTSHATVSRRIDRLEFALKVKLFERNPRGYV
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCEE
LTTMGQRFVETAERIERETEQLQLDISDGMTAQRGVVRLSTLEGFGNFFLADRLSDFVGR
EHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHCCEEEEEEHHHHHHHHHHHHHHHHHCC
YPNISLELVAIQQIMSLSRKEADVAVALAAPKAGPYHSEVLTPYTLHVYGARSYLAGHPL
CCCCEEHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHCCCCEEEEEECCHHHHCCCCC
IRTRNDLGSHRFAGYIDDMIFTPGLDYLGELQPGLRAHFQSSSILTQLKAVRQGLGLCVL
EEECCCCCCHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHCHHHHHHHHHHHHHCCCEEEH
PHFMAKDEPDLEIVLPDEIALQRTYWLICHRDLIGMPRVKALRDFLVDSVAANRGCFLRE
HHHHCCCCCCEEEECCCHHHHHHHHEEEEEHHHCCCCHHHHHHHHHHHHHHCCCCHHHHH
ILSAPAGSRRALEHQ
HHCCCCCCCCCCCCC
>Mature Secondary Structure
MNPNFTWDDLQFFLAVARTGQLSTAARRLRTSHATVSRRIDRLEFALKVKLFERNPRGYV
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCEE
LTTMGQRFVETAERIERETEQLQLDISDGMTAQRGVVRLSTLEGFGNFFLADRLSDFVGR
EHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHCCEEEEEEHHHHHHHHHHHHHHHHHCC
YPNISLELVAIQQIMSLSRKEADVAVALAAPKAGPYHSEVLTPYTLHVYGARSYLAGHPL
CCCCEEHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHCCCCEEEEEECCHHHHCCCCC
IRTRNDLGSHRFAGYIDDMIFTPGLDYLGELQPGLRAHFQSSSILTQLKAVRQGLGLCVL
EEECCCCCCHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHCHHHHHHHHHHHHHCCCEEEH
PHFMAKDEPDLEIVLPDEIALQRTYWLICHRDLIGMPRVKALRDFLVDSVAANRGCFLRE
HHHHCCCCCCEEEECCCHHHHHHHHEEEEEHHHCCCCHHHHHHHHHHHHHHCCCCHHHHH
ILSAPAGSRRALEHQ
HHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]