Click here to switch to the map view.

The map label for this gene is gsiC [H]

Identifier: 150398052

GI number: 150398052

Start: 2980900

End: 2981826

Strand: Reverse

Name: gsiC [H]

Synonym: Smed_2854

Alternate gene names: 150398052

Gene position: 2981826-2980900 (Counterclockwise)

Preceding gene: 150398053

Following gene: 150398051

Centisome position: 78.84

GC content: 62.24

Gene sequence:

>927_bases
ATGATCCGCTTCGTTCTCGTTCGGCTGCTCAGAGCCGTGATCACGATCCTGGCCGTCGTGACCTTCGCTTTCGTCGTGCT
GCGCATGTCGGGCGACCCGGCACAGGTGATGCTTGGTCCCGACGTGCCGCAAGACGCCGTCGATGCGTTCCGCAGAGCCT
GGGGCCTCGACCAGCCTCTCTGGATACAATATCTCGCCTATCTCAAGTCGATCTTCACCGGCGATTTCGGTGTGTCCATG
CGCGACAAGGCGTCCGCACTCCAGCTGGTCCTGGAGCGCGTGCCGGCGACGCTGCAACTGACGCTTCCGGCGCTGATCCT
TAAGCTGATGATCGGCATCCCCGCCGGCGTCTATGCGGCGCTCCATCGCCAGAGTTTCGCCGATCGCGGCGTGATCACGC
TGGCGATCATAGGCTTTACCGTCCCGTCCTTCGTTATGGGTCTCGTGCTCGTACTGATCTTTTCGGTGATACTCGGAGTG
TTGCCCTCCGGAGGCCAGGATACGTGGGTGCATGGCGTTCTGCCGACGATCACGATGAGTATTGGCGGGATCGGCATTCT
CGCCCGTTTCTCGCGTAGCGCCATGATCGAGGTGCTGGGGCAGCCCTATATCCGCACGGCCTCGGCGAAGGGGCTGAAAT
GGCGCGACGTCATCTGGAGCCATGCACTCCCCAATGCCGCGGTTCCGATCGTGACCATTGTCGGCTTCATGGTCGGCTCG
CTGATTGCCGGCGCTGTGGTGGTGGAGTCGATTTTCTCCTGGCCCGGCATCGGGCGGCTGCTGATCGTTTCGGTCAGCAA
CCGCGACCTCGCCGTCGTGCAGTGCATCCTGCTGATCATCGCTGCGGCAATGGTGATGTCGAATCTCGTCGTCGACCTGC
TTTATGGCTGGCTGGACCCGCGGCTGCGTTCGCATGCCGCGCATTAG

Upstream 100 bases:

>100_bases
CCAGTTCGCCTGCGCTTCGCCGGATCGGCGATGGTCGTACGGCGGCCTGTCATGCCGTTGCGGGGGAAACCGCGTCGATC
GAGACGATGAGGAGAATGGC

Downstream 100 bases:

>100_bases
AGCAATTCCGCTTTTCCCCGAATCGCGGAATTTCTCCAACCCGTTTGTTTTTTTGCAATTCCGGACGGAAAGCCGCTGCG
GACTTTCCTGGAATTGCTCC

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MIRFVLVRLLRAVITILAVVTFAFVVLRMSGDPAQVMLGPDVPQDAVDAFRRAWGLDQPLWIQYLAYLKSIFTGDFGVSM
RDKASALQLVLERVPATLQLTLPALILKLMIGIPAGVYAALHRQSFADRGVITLAIIGFTVPSFVMGLVLVLIFSVILGV
LPSGGQDTWVHGVLPTITMSIGGIGILARFSRSAMIEVLGQPYIRTASAKGLKWRDVIWSHALPNAAVPIVTIVGFMVGS
LIAGAVVVESIFSWPGIGRLLIVSVSNRDLAVVQCILLIIAAAMVMSNLVVDLLYGWLDPRLRSHAAH

Sequences:

>Translated_308_residues
MIRFVLVRLLRAVITILAVVTFAFVVLRMSGDPAQVMLGPDVPQDAVDAFRRAWGLDQPLWIQYLAYLKSIFTGDFGVSM
RDKASALQLVLERVPATLQLTLPALILKLMIGIPAGVYAALHRQSFADRGVITLAIIGFTVPSFVMGLVLVLIFSVILGV
LPSGGQDTWVHGVLPTITMSIGGIGILARFSRSAMIEVLGQPYIRTASAKGLKWRDVIWSHALPNAAVPIVTIVGFMVGS
LIAGAVVVESIFSWPGIGRLLIVSVSNRDLAVVQCILLIIAAAMVMSNLVVDLLYGWLDPRLRSHAAH
>Mature_308_residues
MIRFVLVRLLRAVITILAVVTFAFVVLRMSGDPAQVMLGPDVPQDAVDAFRRAWGLDQPLWIQYLAYLKSIFTGDFGVSM
RDKASALQLVLERVPATLQLTLPALILKLMIGIPAGVYAALHRQSFADRGVITLAIIGFTVPSFVMGLVLVLIFSVILGV
LPSGGQDTWVHGVLPTITMSIGGIGILARFSRSAMIEVLGQPYIRTASAKGLKWRDVIWSHALPNAAVPIVTIVGFMVGS
LIAGAVVVESIFSWPGIGRLLIVSVSNRDLAVVQCILLIIAAAMVMSNLVVDLLYGWLDPRLRSHAAH

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=304, Percent_Identity=38.1578947368421, Blast_Score=232, Evalue=3e-62,
Organism=Escherichia coli, GI1789888, Length=314, Percent_Identity=38.5350318471338, Blast_Score=214, Evalue=5e-57,
Organism=Escherichia coli, GI1789965, Length=342, Percent_Identity=37.4269005847953, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1787497, Length=310, Percent_Identity=35.8064516129032, Blast_Score=191, Evalue=7e-50,
Organism=Escherichia coli, GI1787761, Length=325, Percent_Identity=36, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1787550, Length=272, Percent_Identity=27.9411764705882, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1788504, Length=269, Percent_Identity=26.3940520446097, Blast_Score=105, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33255; Mature: 33255

Theoretical pI: Translated: 10.43; Mature: 10.43

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRFVLVRLLRAVITILAVVTFAFVVLRMSGDPAQVMLGPDVPQDAVDAFRRAWGLDQPL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHCCCCHH
WIQYLAYLKSIFTGDFGVSMRDKASALQLVLERVPATLQLTLPALILKLMIGIPAGVYAA
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHH
LHRQSFADRGVITLAIIGFTVPSFVMGLVLVLIFSVILGVLPSGGQDTWVHGVLPTITMS
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
IGGIGILARFSRSAMIEVLGQPYIRTASAKGLKWRDVIWSHALPNAAVPIVTIVGFMVGS
HCHHHHHHHHHHHHHHHHHCCCHHEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LIAGAVVVESIFSWPGIGRLLIVSVSNRDLAVVQCILLIIAAAMVMSNLVVDLLYGWLDP
HHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
RLRSHAAH
HHHHCCCC
>Mature Secondary Structure
MIRFVLVRLLRAVITILAVVTFAFVVLRMSGDPAQVMLGPDVPQDAVDAFRRAWGLDQPL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHCCCCHH
WIQYLAYLKSIFTGDFGVSMRDKASALQLVLERVPATLQLTLPALILKLMIGIPAGVYAA
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHH
LHRQSFADRGVITLAIIGFTVPSFVMGLVLVLIFSVILGVLPSGGQDTWVHGVLPTITMS
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
IGGIGILARFSRSAMIEVLGQPYIRTASAKGLKWRDVIWSHALPNAAVPIVTIVGFMVGS
HCHHHHHHHHHHHHHHHHHCCCHHEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LIAGAVVVESIFSWPGIGRLLIVSVSNRDLAVVQCILLIIAAAMVMSNLVVDLLYGWLDP
HHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
RLRSHAAH
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA