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The map label for this gene is appC [H]

Identifier: 150398051

GI number: 150398051

Start: 2979899

End: 2980780

Strand: Reverse

Name: appC [H]

Synonym: Smed_2853

Alternate gene names: 150398051

Gene position: 2980780-2979899 (Counterclockwise)

Preceding gene: 150398052

Following gene: 150398050

Centisome position: 78.82

GC content: 63.15

Gene sequence:

>882_bases
ATGGCATCCGTCGACATGGCAGAGAGATCGCAGCTAGCAGGATGGCTTCGAGGCTCGATCTCCTCCTTCCGCCGCAAGGC
ACCGCTCTCGGTCGCGTTCGGCATCTTCTGGCTGGCAGCCATGGTCGCCATCGCGCTTTTCGCCGACTACCTGCGGCCCT
ATGACATCACGGCCATGGACCTGACGAGCCGGCTATCGGCGCCGGGAGCGCTCAGGCACTTGCTCGGCACCGACGAGCTT
GGCCGGGACGTGTTGTCGCGCTTGATCCAGTCTGTCCGCGTTTCGCTGATCATAGCGTTCGGCGCGACGGTGCTTTCGGC
AGTCTTCGGCACAGCGCTCGGTTTCGCGGCTGCGCGCTTTCGCGGTATTGTCGAGCATCTGGTGCTCGCGCTTGCGGATT
TTCAGGCAGCTCTTCCGTTTCTCATCATGTCGCTCGCGGTGCTGGCCTTTTTCGGCTCCTCCATGGTCCTGCTCGTCTGC
CTCATGGGCTTCTATGGCTGGGAACGCTATGCGCGCATCGCCCGCGGCCTGGCGATCTCGGCCGGCGCACAGGGCTATGC
CGCGGCGGTGGTGCAACTCGGCGCTACCCCGGCCCGGGTCTATCTGCGCCATATCCTGCCCAATGTAGCATCGACTCTGA
TCGTATCGATGACGCTGACGTTTCCGGAGATCATCCTGATGGAGAGCGGGCTGTCCTTCCTCGGGCTCGGCGTGCAACCC
CCGGAAACGAGCCTTGGCAATATGGTCGGGTTCGGGCGTGAATATCTGACCCGGGCTCCCTGGATCATGCTCGCTCCGGC
TGCCGTGATCATGCTCACCACCCTTTCCATCTCGCTTGTAGGCGACTGGCTCCGCGACAAGCTCGATCCAACCGTGCGTT
GA

Upstream 100 bases:

>100_bases
GAATCGCGGAATTTCTCCAACCCGTTTGTTTTTTTGCAATTCCGGACGGAAAGCCGCTGCGGACTTTCCTGGAATTGCTC
CGGATCCAAGGAGATGCGCT

Downstream 100 bases:

>100_bases
GAGGCCATGACTAAGATCATCGGCCACCGCGGCGCCCGCAATCTCTGGCCTGAGAACTCGCTTACGGGCTTCCGAAACGC
GCTTCGGCTCGGTGTCGACG

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MASVDMAERSQLAGWLRGSISSFRRKAPLSVAFGIFWLAAMVAIALFADYLRPYDITAMDLTSRLSAPGALRHLLGTDEL
GRDVLSRLIQSVRVSLIIAFGATVLSAVFGTALGFAAARFRGIVEHLVLALADFQAALPFLIMSLAVLAFFGSSMVLLVC
LMGFYGWERYARIARGLAISAGAQGYAAAVVQLGATPARVYLRHILPNVASTLIVSMTLTFPEIILMESGLSFLGLGVQP
PETSLGNMVGFGREYLTRAPWIMLAPAAVIMLTTLSISLVGDWLRDKLDPTVR

Sequences:

>Translated_293_residues
MASVDMAERSQLAGWLRGSISSFRRKAPLSVAFGIFWLAAMVAIALFADYLRPYDITAMDLTSRLSAPGALRHLLGTDEL
GRDVLSRLIQSVRVSLIIAFGATVLSAVFGTALGFAAARFRGIVEHLVLALADFQAALPFLIMSLAVLAFFGSSMVLLVC
LMGFYGWERYARIARGLAISAGAQGYAAAVVQLGATPARVYLRHILPNVASTLIVSMTLTFPEIILMESGLSFLGLGVQP
PETSLGNMVGFGREYLTRAPWIMLAPAAVIMLTTLSISLVGDWLRDKLDPTVR
>Mature_292_residues
ASVDMAERSQLAGWLRGSISSFRRKAPLSVAFGIFWLAAMVAIALFADYLRPYDITAMDLTSRLSAPGALRHLLGTDELG
RDVLSRLIQSVRVSLIIAFGATVLSAVFGTALGFAAARFRGIVEHLVLALADFQAALPFLIMSLAVLAFFGSSMVLLVCL
MGFYGWERYARIARGLAISAGAQGYAAAVVQLGATPARVYLRHILPNVASTLIVSMTLTFPEIILMESGLSFLGLGVQPP
ETSLGNMVGFGREYLTRAPWIMLAPAAVIMLTTLSISLVGDWLRDKLDPTVR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=253, Percent_Identity=33.201581027668, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1789889, Length=243, Percent_Identity=34.9794238683128, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1787760, Length=267, Percent_Identity=31.8352059925094, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1789964, Length=255, Percent_Identity=35.6862745098039, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1787498, Length=260, Percent_Identity=33.8461538461538, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1787549, Length=277, Percent_Identity=29.2418772563177, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1788505, Length=231, Percent_Identity=28.1385281385281, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31529; Mature: 31398

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASVDMAERSQLAGWLRGSISSFRRKAPLSVAFGIFWLAAMVAIALFADYLRPYDITAMD
CCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
LTSRLSAPGALRHLLGTDELGRDVLSRLIQSVRVSLIIAFGATVLSAVFGTALGFAAARF
HHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGIVEHLVLALADFQAALPFLIMSLAVLAFFGSSMVLLVCLMGFYGWERYARIARGLAIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHC
AGAQGYAAAVVQLGATPARVYLRHILPNVASTLIVSMTLTFPEIILMESGLSFLGLGVQP
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCC
PETSLGNMVGFGREYLTRAPWIMLAPAAVIMLTTLSISLVGDWLRDKLDPTVR
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ASVDMAERSQLAGWLRGSISSFRRKAPLSVAFGIFWLAAMVAIALFADYLRPYDITAMD
CCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
LTSRLSAPGALRHLLGTDELGRDVLSRLIQSVRVSLIIAFGATVLSAVFGTALGFAAARF
HHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGIVEHLVLALADFQAALPFLIMSLAVLAFFGSSMVLLVCLMGFYGWERYARIARGLAIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHC
AGAQGYAAAVVQLGATPARVYLRHILPNVASTLIVSMTLTFPEIILMESGLSFLGLGVQP
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCC
PETSLGNMVGFGREYLTRAPWIMLAPAAVIMLTTLSISLVGDWLRDKLDPTVR
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]