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The map label for this gene is cobM [H]

Identifier: 150398010

GI number: 150398010

Start: 2937405

End: 2938205

Strand: Reverse

Name: cobM [H]

Synonym: Smed_2812

Alternate gene names: 150398010

Gene position: 2938205-2937405 (Counterclockwise)

Preceding gene: 150398011

Following gene: 150397999

Centisome position: 77.69

GC content: 67.17

Gene sequence:

>801_bases
GTGAACCGCTCATCGGGCAACGCATTTTCGAGAGGAAAGATCATGACGGTTCATTTCATCGGGGCGGGCCCGGGCGCGGC
AGACCTCATCACGGTCAGGGGCAGAGACTTGATCGGCCGCTGCCCCGTCTGCCTATACGCCGGCTCGATCGTTTCGACCG
AGCTCCTGCAATTTTGCCCGCCCGGCGCTCGCATCGTCGATACGGCGCCGATGTCGCTGGACGAGATCGAAGCGGAATAT
GTGCGCGCAGCGGCGGCGGGTGAGGATGTCGCCCGGCTGCATTCCGGCGACCTTTCCGTCTGGAGCGCGGTGGCCGAACA
GATCCGCCGGCTGGAGAAGCATGGCATCGCCTACACGATGACGCCCGGCGTACCCGCCTTCGCTGCCGCCGCCGCGACGC
TTGGCCGCGAACTGACGATCCCCGCGGTCGCTCAGAGCCTGGTGTTGACGCGCGTCTCCGGCCGGGCCTCGCCCATGCCG
AACAGCGAGACGCTCGCAGCGTTCGGCGCCACCGGTTCGACACTCGCCATCCATCTCGCAATCCACGCGCTCGGACAGGT
GGTGGAGGAACTGACCCCACTATACGGCGCCGATTGCCCGGTCGCGATCGTGGTCAAGGCCTCCTGGCCGGACGAACGCG
TCGTCCGCGGCAGGCTTAGCGACATCGCAGCCAGGGTCGCGGCCGAACCGATCGAACGCACCGCGCTGATCTTCGTCGGG
CCGGGGCTGGAGGCGTCGGATTTCCGCGAAAGCTCGCTCTACGACCCGGCATATCAACGGCGCTTCCGCGGGCGCGATTG
A

Upstream 100 bases:

>100_bases
GTTCGCTGATCCGCATCGACATCGCCCGAGCCTCGCCCGTCGGCACGATGACGGGCTGGCGGCCCGCCATGCCGGTCATG
CAATGGTCGTGGGTCAGGGC

Downstream 100 bases:

>100_bases
AGCGACAGCACCGCGCAGTTCCTGCGCACATTACTCTTCGATCTTGCTGCCCGAAGGCCGCGACTTCCGTGGAACCCCCG
GCCGGTTCTCGAAGCGGTCG

Product: precorrin-4 C11-methyltransferase

Products: NA

Alternate protein names: Precorrin-3 methylase [H]

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MNRSSGNAFSRGKIMTVHFIGAGPGAADLITVRGRDLIGRCPVCLYAGSIVSTELLQFCPPGARIVDTAPMSLDEIEAEY
VRAAAAGEDVARLHSGDLSVWSAVAEQIRRLEKHGIAYTMTPGVPAFAAAAATLGRELTIPAVAQSLVLTRVSGRASPMP
NSETLAAFGATGSTLAIHLAIHALGQVVEELTPLYGADCPVAIVVKASWPDERVVRGRLSDIAARVAAEPIERTALIFVG
PGLEASDFRESSLYDPAYQRRFRGRD

Sequences:

>Translated_266_residues
MNRSSGNAFSRGKIMTVHFIGAGPGAADLITVRGRDLIGRCPVCLYAGSIVSTELLQFCPPGARIVDTAPMSLDEIEAEY
VRAAAAGEDVARLHSGDLSVWSAVAEQIRRLEKHGIAYTMTPGVPAFAAAAATLGRELTIPAVAQSLVLTRVSGRASPMP
NSETLAAFGATGSTLAIHLAIHALGQVVEELTPLYGADCPVAIVVKASWPDERVVRGRLSDIAARVAAEPIERTALIFVG
PGLEASDFRESSLYDPAYQRRFRGRD
>Mature_266_residues
MNRSSGNAFSRGKIMTVHFIGAGPGAADLITVRGRDLIGRCPVCLYAGSIVSTELLQFCPPGARIVDTAPMSLDEIEAEY
VRAAAAGEDVARLHSGDLSVWSAVAEQIRRLEKHGIAYTMTPGVPAFAAAAATLGRELTIPAVAQSLVLTRVSGRASPMP
NSETLAAFGATGSTLAIHLAIHALGQVVEELTPLYGADCPVAIVVKASWPDERVVRGRLSDIAARVAAEPIERTALIFVG
PGLEASDFRESSLYDPAYQRRFRGRD

Specific function: Catalyzes the methylation of C-11 in precorrin-4 to form precorrin-5 [H]

COG id: COG2875

COG function: function code H; Precorrin-4 methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789768, Length=238, Percent_Identity=26.890756302521, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR006362
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.133 [H]

Molecular weight: Translated: 28153; Mature: 28153

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00839 SUMT_1 ; PS00840 SUMT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRSSGNAFSRGKIMTVHFIGAGPGAADLITVRGRDLIGRCPVCLYAGSIVSTELLQFCP
CCCCCCCCCCCCEEEEEEEEECCCCCCCEEEECCCCCCCCCCHHHHCCHHHHHHHHHHCC
PGARIVDTAPMSLDEIEAEYVRAAAAGEDVARLHSGDLSVWSAVAEQIRRLEKHGIAYTM
CCCEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEE
TPGVPAFAAAAATLGRELTIPAVAQSLVLTRVSGRASPMPNSETLAAFGATGSTLAIHLA
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCHHHHHHH
IHALGQVVEELTPLYGADCPVAIVVKASWPDERVVRGRLSDIAARVAAEPIERTALIFVG
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
PGLEASDFRESSLYDPAYQRRFRGRD
CCCCHHHCCHHCCCCHHHHHHCCCCC
>Mature Secondary Structure
MNRSSGNAFSRGKIMTVHFIGAGPGAADLITVRGRDLIGRCPVCLYAGSIVSTELLQFCP
CCCCCCCCCCCCEEEEEEEEECCCCCCCEEEECCCCCCCCCCHHHHCCHHHHHHHHHHCC
PGARIVDTAPMSLDEIEAEYVRAAAAGEDVARLHSGDLSVWSAVAEQIRRLEKHGIAYTM
CCCEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEE
TPGVPAFAAAAATLGRELTIPAVAQSLVLTRVSGRASPMPNSETLAAFGATGSTLAIHLA
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCHHHHHHH
IHALGQVVEELTPLYGADCPVAIVVKASWPDERVVRGRLSDIAARVAAEPIERTALIFVG
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
PGLEASDFRESSLYDPAYQRRFRGRD
CCCCHHHCCHHCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521; 8226690 [H]