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The map label for this gene is cobL [H]

Identifier: 150398011

GI number: 150398011

Start: 2938202

End: 2939443

Strand: Reverse

Name: cobL [H]

Synonym: Smed_2813

Alternate gene names: 150398011

Gene position: 2939443-2938202 (Counterclockwise)

Preceding gene: 150398013

Following gene: 150398010

Centisome position: 77.72

GC content: 66.99

Gene sequence:

>1242_bases
GTGGCTGACATGTCGAACAACGGTTCCACCATCGTCGCTCCCTGGCTCATCATAATCGGCATCGGAGAGGACGGTGTAGC
CGGTCTCGGCGAAGAGGCCAAGCGCCTCATCCAGGCGGCACCCGTCGTCTTCGGCGGCGCCCGGCACATGGAGCTTGCGT
CTGCGCTGATCAGGGGCGAGCGCCAGATATGGCAGAGTCCGTTTGAAAAATCGGTAGAGGCCATCGTCGCCCGGCGCGGC
AGCCCCGTCGTGGTGCTCGCCTCGGGCGATCCCTTCCTCTACGGCATCGGCGCTACGCTCACGCGCCGCATCGATGCCGC
GGAAATGCGCACCATCCCCGCTCCGTCCGCTTTCAGCCTTGCCGCGTCCCGGCTAGGCTGGCCCTTGCAGGAGGTCACGA
CCATTTCGCTGCACGGCCGCCCGCTCGATCTCATAAGGCCGCATCTGCAGCCGGGGGCGCGCGTCCTGGCATTGACCTCG
GATGAACACGGGCCGAAGGCGCTTGCCGGCCTGCTCTGTGAAAACGGCTTCGGTCAGTCACGACTTACGGTTCTAGAAGC
GCTTGGCGGCAACAACGAACATGTCTCCAGTCATCGCGCCGAGCGCTTTTCGCTCGAAGACGTCCAAGCGCTGAACGTCT
GCGCGGTGGAGGTAATCGCGGGCACCGACGCTCGCGTGCTTCCGCTTGGCGGAGGGCTGGACGACCTGTTGTTCGAGCAC
GACGGCCAGATCACCAAAAGGGAGGTTCGGGCACTGACGCTCTCGGCGCTGGCGCCGCGCCGGGGTGAACTCCTCTGGGA
TATCGGAGCCGGCTCCGGTTCGATCGCCATCGAATGGATGCTCGCCGACCCGGCGATGCGGGCGATCGCCATAGAGGCTT
CGCCGGAGCGGGTCGCGCGGATCGGCCGCAATGCATTTCGCTTCGGTGTCCCGGGGCTTGTGGTTGTGGAAGGACGTGCG
CCGGAGGCGTTGCTGCAACTCCCGCGCCCGGATGTGATCTTCATCGGCGGCGGCGGAAGCGAGCCCGGCGTGCTGGACGC
GGCCATCGCAGCGCTCGTGCCCGGCGGACGGCTGGTCGCCAATGCCGTGACGACGGAAATGGAAGCGGTGCTGCTCGCCC
AGCATGCGCGGCTCGGCGGTTCGCTGATCCGCATCGACATCGCCCGAGCCTCGCCCGTCGGCACGATGACGGGCTGGCGG
CCCGCCATGCCGGTCATGCAATGGTCGTGGGTCAGGGCGTGA

Upstream 100 bases:

>100_bases
AAGGGAGACCGCAGCGTCGTAGCGCGGATCGGAGGCAAGGTGCTCCGCGAGCTGCCGCGCCTCGGTCGTTCCGCCGAGGA
TCAGAATGCGAGGCTTGCCC

Downstream 100 bases:

>100_bases
ACCGCTCATCGGGCAACGCATTTTCGAGAGGAAAGATCATGACGGTTCATTTCATCGGGGCGGGCCCGGGCGCGGCAGAC
CTCATCACGGTCAGGGGCAG

Product: precorrin-6y C5,15-methyltransferase subunit CbiE

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MADMSNNGSTIVAPWLIIIGIGEDGVAGLGEEAKRLIQAAPVVFGGARHMELASALIRGERQIWQSPFEKSVEAIVARRG
SPVVVLASGDPFLYGIGATLTRRIDAAEMRTIPAPSAFSLAASRLGWPLQEVTTISLHGRPLDLIRPHLQPGARVLALTS
DEHGPKALAGLLCENGFGQSRLTVLEALGGNNEHVSSHRAERFSLEDVQALNVCAVEVIAGTDARVLPLGGGLDDLLFEH
DGQITKREVRALTLSALAPRRGELLWDIGAGSGSIAIEWMLADPAMRAIAIEASPERVARIGRNAFRFGVPGLVVVEGRA
PEALLQLPRPDVIFIGGGGSEPGVLDAAIAALVPGGRLVANAVTTEMEAVLLAQHARLGGSLIRIDIARASPVGTMTGWR
PAMPVMQWSWVRA

Sequences:

>Translated_413_residues
MADMSNNGSTIVAPWLIIIGIGEDGVAGLGEEAKRLIQAAPVVFGGARHMELASALIRGERQIWQSPFEKSVEAIVARRG
SPVVVLASGDPFLYGIGATLTRRIDAAEMRTIPAPSAFSLAASRLGWPLQEVTTISLHGRPLDLIRPHLQPGARVLALTS
DEHGPKALAGLLCENGFGQSRLTVLEALGGNNEHVSSHRAERFSLEDVQALNVCAVEVIAGTDARVLPLGGGLDDLLFEH
DGQITKREVRALTLSALAPRRGELLWDIGAGSGSIAIEWMLADPAMRAIAIEASPERVARIGRNAFRFGVPGLVVVEGRA
PEALLQLPRPDVIFIGGGGSEPGVLDAAIAALVPGGRLVANAVTTEMEAVLLAQHARLGGSLIRIDIARASPVGTMTGWR
PAMPVMQWSWVRA
>Mature_412_residues
ADMSNNGSTIVAPWLIIIGIGEDGVAGLGEEAKRLIQAAPVVFGGARHMELASALIRGERQIWQSPFEKSVEAIVARRGS
PVVVLASGDPFLYGIGATLTRRIDAAEMRTIPAPSAFSLAASRLGWPLQEVTTISLHGRPLDLIRPHLQPGARVLALTSD
EHGPKALAGLLCENGFGQSRLTVLEALGGNNEHVSSHRAERFSLEDVQALNVCAVEVIAGTDARVLPLGGGLDDLLFEHD
GQITKREVRALTLSALAPRRGELLWDIGAGSGSIAIEWMLADPAMRAIAIEASPERVARIGRNAFRFGVPGLVVVEGRAP
EALLQLPRPDVIFIGGGGSEPGVLDAAIAALVPGGRLVANAVTTEMEAVLLAQHARLGGSLIRIDIARASPVGTMTGWRP
AMPVMQWSWVRA

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2241

COG function: function code H; Precorrin-6B methylase 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 43629; Mature: 43498

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADMSNNGSTIVAPWLIIIGIGEDGVAGLGEEAKRLIQAAPVVFGGARHMELASALIRGE
CCCCCCCCCEEEEEEEEEEECCCCCCCCCCHHHHHHHHHCCCEECCCHHHHHHHHHHHHH
RQIWQSPFEKSVEAIVARRGSPVVVLASGDPFLYGIGATLTRRIDAAEMRTIPAPSAFSL
HHHHHCHHHHHHHHHHHCCCCCEEEEECCCCEEEECCHHHHHHCCHHHHCCCCCCCHHHH
AASRLGWPLQEVTTISLHGRPLDLIRPHLQPGARVLALTSDEHGPKALAGLLCENGFGQS
HHHHHCCCHHHEEEEEECCCCHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCH
RLTVLEALGGNNEHVSSHRAERFSLEDVQALNVCAVEVIAGTDARVLPLGGGLDDLLFEH
HHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHEEEEEEEECCCCEEEECCCCHHHHHHHC
DGQITKREVRALTLSALAPRRGELLWDIGAGSGSIAIEWMLADPAMRAIAIEASPERVAR
CCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEEEECCCEEEEEEECCHHHHHH
IGRNAFRFGVPGLVVVEGRAPEALLQLPRPDVIFIGGGGSEPGVLDAAIAALVPGGRLVA
HCCHHEEECCCCEEEEECCCCHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEH
NAVTTEMEAVLLAQHARLGGSLIRIDIARASPVGTMTGWRPAMPVMQWSWVRA
HHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEECCC
>Mature Secondary Structure 
ADMSNNGSTIVAPWLIIIGIGEDGVAGLGEEAKRLIQAAPVVFGGARHMELASALIRGE
CCCCCCCCEEEEEEEEEEECCCCCCCCCCHHHHHHHHHCCCEECCCHHHHHHHHHHHHH
RQIWQSPFEKSVEAIVARRGSPVVVLASGDPFLYGIGATLTRRIDAAEMRTIPAPSAFSL
HHHHHCHHHHHHHHHHHCCCCCEEEEECCCCEEEECCHHHHHHCCHHHHCCCCCCCHHHH
AASRLGWPLQEVTTISLHGRPLDLIRPHLQPGARVLALTSDEHGPKALAGLLCENGFGQS
HHHHHCCCHHHEEEEEECCCCHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCH
RLTVLEALGGNNEHVSSHRAERFSLEDVQALNVCAVEVIAGTDARVLPLGGGLDDLLFEH
HHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHEEEEEEEECCCCEEEECCCCHHHHHHHC
DGQITKREVRALTLSALAPRRGELLWDIGAGSGSIAIEWMLADPAMRAIAIEASPERVAR
CCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEEEECCCEEEEEEECCHHHHHH
IGRNAFRFGVPGLVVVEGRAPEALLQLPRPDVIFIGGGGSEPGVLDAAIAALVPGGRLVA
HCCHHEEECCCCEEEEECCCCHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEH
NAVTTEMEAVLLAQHARLGGSLIRIDIARASPVGTMTGWRPAMPVMQWSWVRA
HHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2211521; 1732195 [H]