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The map label for this gene is xylB [H]

Identifier: 150397989

GI number: 150397989

Start: 2910112

End: 2911566

Strand: Reverse

Name: xylB [H]

Synonym: Smed_2791

Alternate gene names: 150397989

Gene position: 2911566-2910112 (Counterclockwise)

Preceding gene: 150397990

Following gene: 150397987

Centisome position: 76.99

GC content: 66.53

Gene sequence:

>1455_bases
ATGTATCTCGGACTGGATCTCGGCACTTCGGGAGTGAAGGCCATGCTGATGGACGAGGAGCAGCGGATCGTCGGCTCCGC
GACCGGAGCGCTCGACGTCGACCGCCCGCATCCCGGCTGGTCGGAACAGAACCCGGCCGACTGGATCCGAGCCGCGGAGG
AGGCGATAGCTCAGCTCAAGGCCGCGCATGCTGAAGCACTTGCCGCCGTCCGCGGGATCGGCCTCTCCGGCCAGATGCAC
GGTGCCACGCTGCTCGACGAAGGGGATGCGGTGCTGCGCCCGTGCATTCTGTGGAACGACACCCGCAGCTTCCGTGAGGC
GGAGGCACTCGATGGCGACCCGCAATTCCGCGCGCTGACGGGCAATATCGTTTTCCCCGGCTTCACCGCTCCGAAACTCG
CCTGGGTGCGCGAAAACGAGCCGGAGATTTTCGCCAGAGTCCGCTGGGTCTTGCTTCCGAAGGACTATCTGCGCCTCTGG
TTGACCGGCGAGCACATGTCCGAAATGTCCGATTCCGCCGGCACCTCCTGGCTCGACACTGGCAAGCGCAAATGGTCGAC
AAGCCTGCTTGCCGCCACGCATCTCGAGGAACGGCAGATGCCGGAACTTGTCGAAGGAACCGATGCGGCCGGTACCGTGC
GGCCCGAACTGGCAAGTCGCTGGGGCATGGGCTCCGGTGTTCTTGTGGCCGGCGGAGCCGGCGACAACGCGGCATCGGCC
TGCGGCATGGGAACCGTCGGGGAGGGGCAGGCCTTTGTCTCACTCGGCACCTCCGGCGTGCTTTTCGCCGCAAATGCAAG
CTATCTTCCCAATCCTGAAAGCGCCGTTCACGCCTTCTGCCATGCGCTGCCGAACACCTGGCATCAGATGGGCGTGATCC
TTTCGGCGACGGACGCCCTGAACTGGCACTCCGGAGTTACGGGCCGGAGTGCGGCCGACCTTACCGGTGAGCTTGGCGAG
AGCCTCAGAGCGCCGGGTTCCGCAACGTTTCTTCCCTATCTTTCCGGCGAGCGGACGCCGCACAACGACGCGGCCATTCG
CGGTGCCTTTGTCGGGCTCGGCCATGAGAGCTCCCGCCCGCTATTGACGCAGGCGGTGCTCGAAGGCGTTTCCTTCGCGA
TCCGCGACAGCCTGGAGGCTCTGCGCGCGGCCGGCACGCAGCTTGAACGGGTCACCGCAATCGGCGGCGGTTCGCGGTCG
CGCTACTGGCTGAAATCCATCGCGACCGCGCTGAACCTGCCGGTCGACTTGCCCGCGGACGGCGATTTCGGCGCCGCCTT
CGGCGCGGCGCGGCTCGGCCTGATCGCTGCCGCCGACGCCGACCCGGTCGCGGTCTGCGCGGCGCCGGAGACGGCGGAAA
CAATCGCGCCCGAGGGACCGCTCGTGCAGGCTTATGAAGATGCCTATCAGCGCTATCGCCGGCTCTACCCGGCGTTAAAG
GGAGCGATGTCGTGA

Upstream 100 bases:

>100_bases
AAAGGCGGACGGGCTGCCCGTGATCGCGGCGCAGGAACGCATCCGCATCGATATTTTCCTGAAGGACAACCTGCCGCTCG
AGCAGGAATAGGAGGACACC

Downstream 100 bases:

>100_bases
GCGGCCGCAGACCATCCGGAGCCGACGCTTTCGCGCTCTCACGTCGGGATCTTGTCCAGAAAGCCGGTCACCCGCTTCAG
CCGGTCGCCCTCGATGGTGG

Product: xylulokinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MYLGLDLGTSGVKAMLMDEEQRIVGSATGALDVDRPHPGWSEQNPADWIRAAEEAIAQLKAAHAEALAAVRGIGLSGQMH
GATLLDEGDAVLRPCILWNDTRSFREAEALDGDPQFRALTGNIVFPGFTAPKLAWVRENEPEIFARVRWVLLPKDYLRLW
LTGEHMSEMSDSAGTSWLDTGKRKWSTSLLAATHLEERQMPELVEGTDAAGTVRPELASRWGMGSGVLVAGGAGDNAASA
CGMGTVGEGQAFVSLGTSGVLFAANASYLPNPESAVHAFCHALPNTWHQMGVILSATDALNWHSGVTGRSAADLTGELGE
SLRAPGSATFLPYLSGERTPHNDAAIRGAFVGLGHESSRPLLTQAVLEGVSFAIRDSLEALRAAGTQLERVTAIGGGSRS
RYWLKSIATALNLPVDLPADGDFGAAFGAARLGLIAAADADPVAVCAAPETAETIAPEGPLVQAYEDAYQRYRRLYPALK
GAMS

Sequences:

>Translated_484_residues
MYLGLDLGTSGVKAMLMDEEQRIVGSATGALDVDRPHPGWSEQNPADWIRAAEEAIAQLKAAHAEALAAVRGIGLSGQMH
GATLLDEGDAVLRPCILWNDTRSFREAEALDGDPQFRALTGNIVFPGFTAPKLAWVRENEPEIFARVRWVLLPKDYLRLW
LTGEHMSEMSDSAGTSWLDTGKRKWSTSLLAATHLEERQMPELVEGTDAAGTVRPELASRWGMGSGVLVAGGAGDNAASA
CGMGTVGEGQAFVSLGTSGVLFAANASYLPNPESAVHAFCHALPNTWHQMGVILSATDALNWHSGVTGRSAADLTGELGE
SLRAPGSATFLPYLSGERTPHNDAAIRGAFVGLGHESSRPLLTQAVLEGVSFAIRDSLEALRAAGTQLERVTAIGGGSRS
RYWLKSIATALNLPVDLPADGDFGAAFGAARLGLIAAADADPVAVCAAPETAETIAPEGPLVQAYEDAYQRYRRLYPALK
GAMS
>Mature_484_residues
MYLGLDLGTSGVKAMLMDEEQRIVGSATGALDVDRPHPGWSEQNPADWIRAAEEAIAQLKAAHAEALAAVRGIGLSGQMH
GATLLDEGDAVLRPCILWNDTRSFREAEALDGDPQFRALTGNIVFPGFTAPKLAWVRENEPEIFARVRWVLLPKDYLRLW
LTGEHMSEMSDSAGTSWLDTGKRKWSTSLLAATHLEERQMPELVEGTDAAGTVRPELASRWGMGSGVLVAGGAGDNAASA
CGMGTVGEGQAFVSLGTSGVLFAANASYLPNPESAVHAFCHALPNTWHQMGVILSATDALNWHSGVTGRSAADLTGELGE
SLRAPGSATFLPYLSGERTPHNDAAIRGAFVGLGHESSRPLLTQAVLEGVSFAIRDSLEALRAAGTQLERVTAIGGGSRS
RYWLKSIATALNLPVDLPADGDFGAAFGAARLGLIAAADADPVAVCAAPETAETIAPEGPLVQAYEDAYQRYRRLYPALK
GAMS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI18860918, Length=526, Percent_Identity=25.4752851711027, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI41393575, Length=439, Percent_Identity=22.3234624145786, Blast_Score=90, Evalue=6e-18,
Organism=Homo sapiens, GI42794763, Length=446, Percent_Identity=21.9730941704036, Blast_Score=87, Evalue=4e-17,
Organism=Escherichia coli, GI1789987, Length=489, Percent_Identity=47.6482617586912, Blast_Score=414, Evalue=1e-117,
Organism=Escherichia coli, GI1790005, Length=502, Percent_Identity=28.0876494023904, Blast_Score=142, Evalue=7e-35,
Organism=Escherichia coli, GI1789168, Length=487, Percent_Identity=23.2032854209446, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1790361, Length=455, Percent_Identity=21.0989010989011, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786249, Length=560, Percent_Identity=24.6428571428571, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787789, Length=507, Percent_Identity=22.0907297830375, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17535599, Length=423, Percent_Identity=25.2955082742317, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17554530, Length=472, Percent_Identity=20.7627118644068, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321633, Length=353, Percent_Identity=26.0623229461756, Blast_Score=95, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24655555, Length=441, Percent_Identity=24.2630385487528, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24655560, Length=441, Percent_Identity=24.2630385487528, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24655570, Length=441, Percent_Identity=24.2630385487528, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24655574, Length=441, Percent_Identity=24.2630385487528, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24655565, Length=441, Percent_Identity=24.2630385487528, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI17864214, Length=405, Percent_Identity=22.962962962963, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24654573, Length=364, Percent_Identity=22.5274725274725, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI19920476, Length=320, Percent_Identity=25.625, Blast_Score=76, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 51125; Mature: 51125

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00933 FGGY_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLGLDLGTSGVKAMLMDEEQRIVGSATGALDVDRPHPGWSEQNPADWIRAAEEAIAQLK
CEEEEECCCCCCEEEEECCHHHHHHCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
AAHAEALAAVRGIGLSGQMHGATLLDEGDAVLRPCILWNDTRSFREAEALDGDPQFRALT
HHHHHHHHHHHCCCCCCCCCCCEEECCCCHHHCCEEEECCCHHHHHHHHCCCCCCEEEEE
GNIVFPGFTAPKLAWVRENEPEIFARVRWVLLPKDYLRLWLTGEHMSEMSDSAGTSWLDT
CCEEECCCCCCCEEEEECCCCCEEEEEEEEEECHHHEEEEECCHHHHHHHHHCCCHHHHC
GKRKWSTSLLAATHLEERQMPELVEGTDAAGTVRPELASRWGMGSGVLVAGGAGDNAASA
CCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHHHHCCCCCCEEEECCCCCCCHHH
CGMGTVGEGQAFVSLGTSGVLFAANASYLPNPESAVHAFCHALPNTWHQMGVILSATDAL
CCCCCCCCCCEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHCEEEEECCCC
NWHSGVTGRSAADLTGELGESLRAPGSATFLPYLSGERTPHNDAAIRGAFVGLGHESSRP
CCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHEEEEEECCCCCCCC
LLTQAVLEGVSFAIRDSLEALRAAGTQLERVTAIGGGSRSRYWLKSIATALNLPVDLPAD
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEEECCCCCCHHHHHHHHHHHCCCEECCCC
GDFGAAFGAARLGLIAAADADPVAVCAAPETAETIAPEGPLVQAYEDAYQRYRRLYPALK
CCCCHHHHHHHHCEEEECCCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
GAMS
HCCC
>Mature Secondary Structure
MYLGLDLGTSGVKAMLMDEEQRIVGSATGALDVDRPHPGWSEQNPADWIRAAEEAIAQLK
CEEEEECCCCCCEEEEECCHHHHHHCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
AAHAEALAAVRGIGLSGQMHGATLLDEGDAVLRPCILWNDTRSFREAEALDGDPQFRALT
HHHHHHHHHHHCCCCCCCCCCCEEECCCCHHHCCEEEECCCHHHHHHHHCCCCCCEEEEE
GNIVFPGFTAPKLAWVRENEPEIFARVRWVLLPKDYLRLWLTGEHMSEMSDSAGTSWLDT
CCEEECCCCCCCEEEEECCCCCEEEEEEEEEECHHHEEEEECCHHHHHHHHHCCCHHHHC
GKRKWSTSLLAATHLEERQMPELVEGTDAAGTVRPELASRWGMGSGVLVAGGAGDNAASA
CCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHHHHCCCCCCEEEECCCCCCCHHH
CGMGTVGEGQAFVSLGTSGVLFAANASYLPNPESAVHAFCHALPNTWHQMGVILSATDAL
CCCCCCCCCCEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHCEEEEECCCC
NWHSGVTGRSAADLTGELGESLRAPGSATFLPYLSGERTPHNDAAIRGAFVGLGHESSRP
CCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHEEEEEECCCCCCCC
LLTQAVLEGVSFAIRDSLEALRAAGTQLERVTAIGGGSRSRYWLKSIATALNLPVDLPAD
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEEECCCCCCHHHHHHHHHHHCCCEECCCC
GDFGAAFGAARLGLIAAADADPVAVCAAPETAETIAPEGPLVQAYEDAYQRYRRLYPALK
CCCCHHHHHHHHCEEEECCCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
GAMS
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6320721; 8041620; 9278503 [H]