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The map label for this gene is glpD [H]

Identifier: 150397897

GI number: 150397897

Start: 2805966

End: 2807501

Strand: Reverse

Name: glpD [H]

Synonym: Smed_2699

Alternate gene names: 150397897

Gene position: 2807501-2805966 (Counterclockwise)

Preceding gene: 150397898

Following gene: 150397896

Centisome position: 74.24

GC content: 64.26

Gene sequence:

>1536_bases
ATGACGGGCGCGCTTTTCGACATTGCCGTTATCGGCGGCGGCATCAATGGAGCAGGGGTGGCCCGCGATGCGGCCGGGCG
CGGCCTGAAGGTGTTGCTTGCCGAACAATCCGATCTTGGCTCAGCCACCTCCTCGGCATCCACCAAACTCATTCACGGCG
GCCTGCGTTATCTCGAACATTACGAGTTTCGGCTGGTACGCCACGCTCTGAAAGAGCGCGAACAGCTCTGGGGAATTGCG
CCCCATATCATCTGGCCCTTGCGGTTCGTGTTGCCGCACCGCAAGGGTCTGCGACCGGCCTGGCTGCTGCGGCTCGGCCT
CTTCCTCTACGATCATCTGGGCGGACGCAAGCTTCTGCCGGGTACAAAGACGCTGCGGCTGAAGAGCCACCCCGCCGGAG
AGCCGTTGCGCGACGTCTCGGCGATCGGCTTTGAATATTCCGATTGCTGGGTGCAGGACAACCGGCTTGTCGTGCTCAAC
GCGCGGGATGCGGCAATGCGGGGTGCGGACATCCGTGTGCGCACCCGTTGCGTCGCGGCGCGCCGCGAGGGCGGTCTCTG
GCAATTGTTGCTTGAAGATACGCAATCCGGCTTGAAGAGCGAAGCTGCGGCCCGCGCTCTGGTCAACGCGGCGGGCCCCT
GGACCGACAAGATCGCGTCCGATGTTGCCGGCATCGGCGCTTCGGGCCGCGTACGCCTCGTACAGGGCAGCCACATCGTG
GTCAAAAAGCTCTACGAGCACGATCGCTGCTATATCTTTCAGAATCCGGACGGTCGCATCTTCTTCGCCATTCCCTATGA
AGAGGACTTCACCCTAATCGGCACGACGGACAGGGACTACAAGGACGCTCCCGAGGCGGTCGCGGCCTCCGCGGAGGAAG
TCGACTATCTGCTTGCGGCAGCATCGTCCTATTTTCGCACCGATCTCACTGAAGCCGACGTCGTTTGGACTTATTCCGGC
GTCCGCGCCCTCTTCCACGACGGCGCCGCCAACGCGCAGGAGACGACCCGCGACTACGTGCTGCAGCTCGATCGGCCGGG
GACGCAGGCGCCGATGCTCTCCGTTTTCGGCGGCAAGATCACCACCTATCGCTGCCTCGCGGAGGACGTGCTGGACAAAC
TCGCCGCGATCTTTCCGGACTGGAACAGGCAGCGAGGCTGGACGGCGACGCAACCGCTGCCGGGCGGCGCCTTTCCGGCC
GGAGCGGCTGATGATCTCGCAAGGGCCATTCACGGCGAGCATCCCTACCTTACCGTGCGGGAGGCGCGCCGGCTTGTACG
CCATTACGGGCTCGAGGCACGAGAGATTCTCGGCAAGGCGCAGGATCGCGCCGATCTCGGCCGTGATTTCGGCGGATCCA
TGACCGAGGCGGAAATCGCCTTTCTGATGGAGCGGGAATTTGCATTGACCGCTGCCGATGCGGTCTGGCGGCGTACGAAA
TCCGGCTTGCGGATGACGAGCGAGGAGATCGGGGCGCTTGACCGATACATGCAGGAGCGGCGCGGAGCCGGCGAGACCAG
GCGCGCCGCCGGATAG

Upstream 100 bases:

>100_bases
TCGATGCGGAGCCGGCCTATGTGGCCGCACGCGAGGGCGGGCACGGCTTCGTCGAAGTGGCGAACCGCATCCTCGACGCG
CGGTCGGGAAAGCACGCGGC

Downstream 100 bases:

>100_bases
ACTTGCCGCTCCCTGAAACGGGGGGCGGGTGGGTGAGGGGAGACGCCGGCGGTATCCGGATCGTCGCCGAATTATTGGAG
GAACCGACCACAGGCGGGAG

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 511; Mature: 510

Protein sequence:

>511_residues
MTGALFDIAVIGGGINGAGVARDAAGRGLKVLLAEQSDLGSATSSASTKLIHGGLRYLEHYEFRLVRHALKEREQLWGIA
PHIIWPLRFVLPHRKGLRPAWLLRLGLFLYDHLGGRKLLPGTKTLRLKSHPAGEPLRDVSAIGFEYSDCWVQDNRLVVLN
ARDAAMRGADIRVRTRCVAARREGGLWQLLLEDTQSGLKSEAAARALVNAAGPWTDKIASDVAGIGASGRVRLVQGSHIV
VKKLYEHDRCYIFQNPDGRIFFAIPYEEDFTLIGTTDRDYKDAPEAVAASAEEVDYLLAAASSYFRTDLTEADVVWTYSG
VRALFHDGAANAQETTRDYVLQLDRPGTQAPMLSVFGGKITTYRCLAEDVLDKLAAIFPDWNRQRGWTATQPLPGGAFPA
GAADDLARAIHGEHPYLTVREARRLVRHYGLEAREILGKAQDRADLGRDFGGSMTEAEIAFLMEREFALTAADAVWRRTK
SGLRMTSEEIGALDRYMQERRGAGETRRAAG

Sequences:

>Translated_511_residues
MTGALFDIAVIGGGINGAGVARDAAGRGLKVLLAEQSDLGSATSSASTKLIHGGLRYLEHYEFRLVRHALKEREQLWGIA
PHIIWPLRFVLPHRKGLRPAWLLRLGLFLYDHLGGRKLLPGTKTLRLKSHPAGEPLRDVSAIGFEYSDCWVQDNRLVVLN
ARDAAMRGADIRVRTRCVAARREGGLWQLLLEDTQSGLKSEAAARALVNAAGPWTDKIASDVAGIGASGRVRLVQGSHIV
VKKLYEHDRCYIFQNPDGRIFFAIPYEEDFTLIGTTDRDYKDAPEAVAASAEEVDYLLAAASSYFRTDLTEADVVWTYSG
VRALFHDGAANAQETTRDYVLQLDRPGTQAPMLSVFGGKITTYRCLAEDVLDKLAAIFPDWNRQRGWTATQPLPGGAFPA
GAADDLARAIHGEHPYLTVREARRLVRHYGLEAREILGKAQDRADLGRDFGGSMTEAEIAFLMEREFALTAADAVWRRTK
SGLRMTSEEIGALDRYMQERRGAGETRRAAG
>Mature_510_residues
TGALFDIAVIGGGINGAGVARDAAGRGLKVLLAEQSDLGSATSSASTKLIHGGLRYLEHYEFRLVRHALKEREQLWGIAP
HIIWPLRFVLPHRKGLRPAWLLRLGLFLYDHLGGRKLLPGTKTLRLKSHPAGEPLRDVSAIGFEYSDCWVQDNRLVVLNA
RDAAMRGADIRVRTRCVAARREGGLWQLLLEDTQSGLKSEAAARALVNAAGPWTDKIASDVAGIGASGRVRLVQGSHIVV
KKLYEHDRCYIFQNPDGRIFFAIPYEEDFTLIGTTDRDYKDAPEAVAASAEEVDYLLAAASSYFRTDLTEADVVWTYSGV
RALFHDGAANAQETTRDYVLQLDRPGTQAPMLSVFGGKITTYRCLAEDVLDKLAAIFPDWNRQRGWTATQPLPGGAFPAG
AADDLARAIHGEHPYLTVREARRLVRHYGLEAREILGKAQDRADLGRDFGGSMTEAEIAFLMEREFALTAADAVWRRTKS
GLRMTSEEIGALDRYMQERRGAGETRRAAG

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=524, Percent_Identity=31.1068702290076, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI285002231, Length=524, Percent_Identity=31.1068702290076, Blast_Score=171, Evalue=2e-42,
Organism=Escherichia coli, GI2367226, Length=471, Percent_Identity=47.3460721868365, Blast_Score=429, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI115534726, Length=512, Percent_Identity=28.90625, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17509253, Length=511, Percent_Identity=30.1369863013699, Blast_Score=140, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6322036, Length=562, Percent_Identity=25.4448398576512, Blast_Score=126, Evalue=9e-30,
Organism=Drosophila melanogaster, GI161077125, Length=528, Percent_Identity=29.1666666666667, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24653942, Length=528, Percent_Identity=29.1666666666667, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24653944, Length=528, Percent_Identity=29.1666666666667, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI20130025, Length=528, Percent_Identity=29.1666666666667, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24586295, Length=386, Percent_Identity=29.5336787564767, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI19921278, Length=510, Percent_Identity=23.1372549019608, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 56340; Mature: 56208

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGALFDIAVIGGGINGAGVARDAAGRGLKVLLAEQSDLGSATSSASTKLIHGGLRYLEH
CCCCEEEEEEEECCCCCCCCCHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
YEFRLVRHALKEREQLWGIAPHIIWPLRFVLPHRKGLRPAWLLRLGLFLYDHLGGRKLLP
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCEECC
GTKTLRLKSHPAGEPLRDVSAIGFEYSDCWVQDNRLVVLNARDAAMRGADIRVRTRCVAA
CCCEEEECCCCCCCCHHHHHHHCCCCCCCEEECCEEEEEECCHHHHCCCCEEEHHHHHHH
RREGGLWQLLLEDTQSGLKSEAAARALVNAAGPWTDKIASDVAGIGASGRVRLVQGSHIV
HCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEECCHHH
VKKLYEHDRCYIFQNPDGRIFFAIPYEEDFTLIGTTDRDYKDAPEAVAASAEEVDYLLAA
HHHHHCCCCEEEEECCCCEEEEEECCCCCEEEEECCCCCCCCCHHHHHCCHHHHHHHHHH
ASSYFRTDLTEADVVWTYSGVRALFHDGAANAQETTRDYVLQLDRPGTQAPMLSVFGGKI
HHHHHHCCCCCCCEEEEHHHHHHHHHCCCCCHHHHHHHHEEEECCCCCCCCHHHHCCCCH
TTYRCLAEDVLDKLAAIFPDWNRQRGWTATQPLPGGAFPAGAADDLARAIHGEHPYLTVR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEHH
EARRLVRHYGLEAREILGKAQDRADLGRDFGGSMTEAEIAFLMEREFALTAADAVWRRTK
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SGLRMTSEEIGALDRYMQERRGAGETRRAAG
HCCEECHHHHHHHHHHHHHHCCCCCHHCCCC
>Mature Secondary Structure 
TGALFDIAVIGGGINGAGVARDAAGRGLKVLLAEQSDLGSATSSASTKLIHGGLRYLEH
CCCEEEEEEEECCCCCCCCCHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
YEFRLVRHALKEREQLWGIAPHIIWPLRFVLPHRKGLRPAWLLRLGLFLYDHLGGRKLLP
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCEECC
GTKTLRLKSHPAGEPLRDVSAIGFEYSDCWVQDNRLVVLNARDAAMRGADIRVRTRCVAA
CCCEEEECCCCCCCCHHHHHHHCCCCCCCEEECCEEEEEECCHHHHCCCCEEEHHHHHHH
RREGGLWQLLLEDTQSGLKSEAAARALVNAAGPWTDKIASDVAGIGASGRVRLVQGSHIV
HCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEECCHHH
VKKLYEHDRCYIFQNPDGRIFFAIPYEEDFTLIGTTDRDYKDAPEAVAASAEEVDYLLAA
HHHHHCCCCEEEEECCCCEEEEEECCCCCEEEEECCCCCCCCCHHHHHCCHHHHHHHHHH
ASSYFRTDLTEADVVWTYSGVRALFHDGAANAQETTRDYVLQLDRPGTQAPMLSVFGGKI
HHHHHHCCCCCCCEEEEHHHHHHHHHCCCCCHHHHHHHHEEEECCCCCCCCHHHHCCCCH
TTYRCLAEDVLDKLAAIFPDWNRQRGWTATQPLPGGAFPAGAADDLARAIHGEHPYLTVR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEHH
EARRLVRHYGLEAREILGKAQDRADLGRDFGGSMTEAEIAFLMEREFALTAADAVWRRTK
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SGLRMTSEEIGALDRYMQERRGAGETRRAAG
HCCEECHHHHHHHHHHHHHHCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157588; 10984043 [H]