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The map label for this gene is hss [H]

Identifier: 150397886

GI number: 150397886

Start: 2791932

End: 2793383

Strand: Direct

Name: hss [H]

Synonym: Smed_2688

Alternate gene names: 150397886

Gene position: 2791932-2793383 (Clockwise)

Preceding gene: 150397884

Following gene: 150397887

Centisome position: 73.82

GC content: 61.57

Gene sequence:

>1452_bases
ATGGCAGACACCACCTATCCGGTTTACGGTGAGATCACCGGTCCCATCGTGATGATCGGCTTCGGTTCGATCGGTCATGG
TACCTTGCCGCTGATCGAGCGCCACTTCAGATACGACAAGAGCCGGCTGATCGTGGTGGAGCCCCGTGAGGACGCCAAGG
ACACGGAGATATTCGCGCGTCACGGCGTCCGGCACGTGCGCGCAGCGGTAACCAAGGACAACTACAAAGAGCTGCTGAAG
CCGCTTCTGACCGAAGGCGGCGGCCAGGGCTTCTGCGTCAATCTCTCGGTCGACACCTCTTCGCTCGACCTCATCAAGCT
TTGCCGCAAGCTGGACGTGCTCTACGTGGACACGGTCGTCGAACCCTGGCTGGGTTTCTACTTCGACGCCGAAAAGGACA
ACGCGGCACGCACGAATTATGCGTTGCGCGAAACGGTCCGCCGCGAGAAGGAGAAGAACCCGGGCGGCACGACTGCCGTT
TCGACCTGCGGCGCCAATCCGGGCATGGTTTCCTGGTTCGTCAAAAAGGCCCTGCTCAACCTCGCCGACGATCTCGGCCT
GAAATACGATGAGCCTCACCAGGACGACCGCGATGGCTGGGCGAAGCTGATGAAGAAAGCGGGCGTCAAGGGCGTTCATA
TCGCCGAGCGCGACACCCAGCGCGCCAAGCACCCGAAGCCCCTCAACGTATTCTGGAACACCTGGTCCGTCGAAGGTTTC
ATCTCTGAAGGGCTGCAGCCAGCCGAACTCGGCTGGGGCACCCACGAGAACTGGATGCCGAAAAACGCCAAGAAGCACAA
AAAGGGCTGCAAGGCGGCGATCTACCTGGAGCAGCCGGGTGCCAATACCCGCGTGCGCAGCTGGTGCCCGACGCCCGGTC
CGCAATACGGATTCCTCGTCACGCACAACGAATCGATCTCGATCGCCGACTTCTTCACCGTCCGCGACAAGAACGGCGAT
GTCGTCTACCGCCCGACCTGCCACTACGCCTATCACCCTGCCAACGACGCGGTTCTTTCGCTGCACGAAATGTTCGGCAA
CGGCGGCAAGGCACAGCCTGAACTGCACGTCCTGGACGAGCATGAGCTGATAGACGGCGTCGACGAGCTCGGCGTGCTGC
TCTACGGTCACGCCAAGAACGCATATTGGTTCGGCTCGCGCCTTTCGCTGGAAGAAACCAGGCGCATCGCGCCCTACCAG
AACGCCACCGGGCTGCAGGTCACGAGCGCCGTTCTTGCCGGCATGGTCTGGGCTCTGGAAAACCCGAAGGCGGGCATCGT
CGAGGCCGACGAAATGGACTACAAGCGCTGCCTCGAAGTGCAGCTCCCCTATCTCGGTCCCGTCGAAGGGCATTATACCG
ACTGGACGCCGCTTGACGGCCGCCCCGGCCTGTTTCCGGAAGATATCGACGCGAAGGACCCCTGGCAGTTCAGGAACATT
CTCGTCCGTTGA

Upstream 100 bases:

>100_bases
TTCCGATTTGACGCCATGCAGGCCCGCCAGGAAGTCGAGGCTCGCTTTCGCGCGCATCCAAGGTACCGCACAGGGACGTT
TTCTCAGGAGAAAGACAAAA

Downstream 100 bases:

>100_bases
AGATCCCGCCTCGCGGACTCTGATCAAGGCCCGGAGCACCCTGTCTCCGGGCCTTTTTTTTGCGAGCGTCGAGCGCGCCA
CGCGCATGCCCGCTCTTGCT

Product: homospermidine synthase

Products: NA

Alternate protein names: HSS [H]

Number of amino acids: Translated: 483; Mature: 482

Protein sequence:

>483_residues
MADTTYPVYGEITGPIVMIGFGSIGHGTLPLIERHFRYDKSRLIVVEPREDAKDTEIFARHGVRHVRAAVTKDNYKELLK
PLLTEGGGQGFCVNLSVDTSSLDLIKLCRKLDVLYVDTVVEPWLGFYFDAEKDNAARTNYALRETVRREKEKNPGGTTAV
STCGANPGMVSWFVKKALLNLADDLGLKYDEPHQDDRDGWAKLMKKAGVKGVHIAERDTQRAKHPKPLNVFWNTWSVEGF
ISEGLQPAELGWGTHENWMPKNAKKHKKGCKAAIYLEQPGANTRVRSWCPTPGPQYGFLVTHNESISIADFFTVRDKNGD
VVYRPTCHYAYHPANDAVLSLHEMFGNGGKAQPELHVLDEHELIDGVDELGVLLYGHAKNAYWFGSRLSLEETRRIAPYQ
NATGLQVTSAVLAGMVWALENPKAGIVEADEMDYKRCLEVQLPYLGPVEGHYTDWTPLDGRPGLFPEDIDAKDPWQFRNI
LVR

Sequences:

>Translated_483_residues
MADTTYPVYGEITGPIVMIGFGSIGHGTLPLIERHFRYDKSRLIVVEPREDAKDTEIFARHGVRHVRAAVTKDNYKELLK
PLLTEGGGQGFCVNLSVDTSSLDLIKLCRKLDVLYVDTVVEPWLGFYFDAEKDNAARTNYALRETVRREKEKNPGGTTAV
STCGANPGMVSWFVKKALLNLADDLGLKYDEPHQDDRDGWAKLMKKAGVKGVHIAERDTQRAKHPKPLNVFWNTWSVEGF
ISEGLQPAELGWGTHENWMPKNAKKHKKGCKAAIYLEQPGANTRVRSWCPTPGPQYGFLVTHNESISIADFFTVRDKNGD
VVYRPTCHYAYHPANDAVLSLHEMFGNGGKAQPELHVLDEHELIDGVDELGVLLYGHAKNAYWFGSRLSLEETRRIAPYQ
NATGLQVTSAVLAGMVWALENPKAGIVEADEMDYKRCLEVQLPYLGPVEGHYTDWTPLDGRPGLFPEDIDAKDPWQFRNI
LVR
>Mature_482_residues
ADTTYPVYGEITGPIVMIGFGSIGHGTLPLIERHFRYDKSRLIVVEPREDAKDTEIFARHGVRHVRAAVTKDNYKELLKP
LLTEGGGQGFCVNLSVDTSSLDLIKLCRKLDVLYVDTVVEPWLGFYFDAEKDNAARTNYALRETVRREKEKNPGGTTAVS
TCGANPGMVSWFVKKALLNLADDLGLKYDEPHQDDRDGWAKLMKKAGVKGVHIAERDTQRAKHPKPLNVFWNTWSVEGFI
SEGLQPAELGWGTHENWMPKNAKKHKKGCKAAIYLEQPGANTRVRSWCPTPGPQYGFLVTHNESISIADFFTVRDKNGDV
VYRPTCHYAYHPANDAVLSLHEMFGNGGKAQPELHVLDEHELIDGVDELGVLLYGHAKNAYWFGSRLSLEETRRIAPYQN
ATGLQVTSAVLAGMVWALENPKAGIVEADEMDYKRCLEVQLPYLGPVEGHYTDWTPLDGRPGLFPEDIDAKDPWQFRNIL
VR

Specific function: Involved in the NAD(+)-dependent synthesis of the polyamine homospermidine from putrescine [H]

COG id: COG5310

COG function: function code Q; Homospermidine synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023181
- InterPro:   IPR016040
- InterPro:   IPR005097 [H]

Pfam domain/function: PF03435 Saccharop_dh [H]

EC number: =2.5.1.44 [H]

Molecular weight: Translated: 54203; Mature: 54072

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADTTYPVYGEITGPIVMIGFGSIGHGTLPLIERHFRYDKSRLIVVEPREDAKDTEIFAR
CCCCCCCEEECCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHH
HGVRHVRAAVTKDNYKELLKPLLTEGGGQGFCVNLSVDTSSLDLIKLCRKLDVLYVDTVV
HCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHCCEEEEHHHH
EPWLGFYFDAEKDNAARTNYALRETVRREKEKNPGGTTAVSTCGANPGMVSWFVKKALLN
HHHHHEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHH
LADDLGLKYDEPHQDDRDGWAKLMKKAGVKGVHIAERDTQRAKHPKPLNVFWNTWSVEGF
HHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCHHHCCCCCCCEEEEECEEEHHH
ISEGLQPAELGWGTHENWMPKNAKKHKKGCKAAIYLEQPGANTRVRSWCPTPGPQYGFLV
HHCCCCHHHCCCCCCCCCCCCCHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEE
THNESISIADFFTVRDKNGDVVYRPTCHYAYHPANDAVLSLHEMFGNGGKAQPELHVLDE
EECCCEEEEEEEEEECCCCCEEECCCCCEEECCCCHHHHHHHHHHCCCCCCCCCEEEECC
HELIDGVDELGVLLYGHAKNAYWFGSRLSLEETRRIAPYQNATGLQVTSAVLAGMVWALE
HHHHCCHHHCCEEEEECCCCCEEECCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHEEC
NPKAGIVEADEMDYKRCLEVQLPYLGPVEGHYTDWTPLDGRPGLFPEDIDAKDPWQFRNI
CCCCCCEECCHHCHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
LVR
HCC
>Mature Secondary Structure 
ADTTYPVYGEITGPIVMIGFGSIGHGTLPLIERHFRYDKSRLIVVEPREDAKDTEIFAR
CCCCCCEEECCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHH
HGVRHVRAAVTKDNYKELLKPLLTEGGGQGFCVNLSVDTSSLDLIKLCRKLDVLYVDTVV
HCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHCCEEEEHHHH
EPWLGFYFDAEKDNAARTNYALRETVRREKEKNPGGTTAVSTCGANPGMVSWFVKKALLN
HHHHHEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHH
LADDLGLKYDEPHQDDRDGWAKLMKKAGVKGVHIAERDTQRAKHPKPLNVFWNTWSVEGF
HHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCHHHCCCCCCCEEEEECEEEHHH
ISEGLQPAELGWGTHENWMPKNAKKHKKGCKAAIYLEQPGANTRVRSWCPTPGPQYGFLV
HHCCCCHHHCCCCCCCCCCCCCHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEE
THNESISIADFFTVRDKNGDVVYRPTCHYAYHPANDAVLSLHEMFGNGGKAQPELHVLDE
EECCCEEEEEEEEEECCCCCEEECCCCCEEECCCCHHHHHHHHHHCCCCCCCCCEEEECC
HELIDGVDELGVLLYGHAKNAYWFGSRLSLEETRRIAPYQNATGLQVTSAVLAGMVWALE
HHHHCCHHHCCEEEEECCCCCEEECCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHEEC
NPKAGIVEADEMDYKRCLEVQLPYLGPVEGHYTDWTPLDGRPGLFPEDIDAKDPWQFRNI
CCCCCCEECCHHCHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
LVR
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]