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The map label for this gene is ygfA [C]

Identifier: 150397844

GI number: 150397844

Start: 2749871

End: 2750452

Strand: Reverse

Name: ygfA [C]

Synonym: Smed_2646

Alternate gene names: 150397844

Gene position: 2750452-2749871 (Counterclockwise)

Preceding gene: 150397846

Following gene: 150397843

Centisome position: 72.73

GC content: 61.86

Gene sequence:

>582_bases
ATGTCACCCAAGGATTTGAAGGCAGCATTGAGAAAGGAGCGTCTGGCGCTCCGCGATGCGATGCCGGCGGAAGCGCGGAT
CGAGGCGAGCCTTGCAATGGCCGACCACGCAAGCGACGTTATCGCGCTCGATCCCGGCCACGTGGTTTCCGGGTTCTGGC
CGATCCGAACGGAGGCCGATATCCGGCCGCTGATGGTGCGGCTGAGGGATCGTGGTGCACGCCTCTGCCTGCCGGTGATC
CTGGACAAGAAGGCGATCATCTTCCGGGAACTGCTCGACGGTATCGCGGTGGTCGAAACCGGCTTCGGCACCACCGGTCC
GGGTCCGGATGCGCCGGAAGTCGATCCGGATATCATGCTCGTTCCTCTTTCCGCCTTCGATGCCATGGGCCATCGGATCG
GCTATGGTGCCGGTTATTATGACCGCGCAATCGATCGCCTGCGTCGCAAAGGCCACATGCCGCGGTTGATCGGGATTGCA
TTCGACTGCCAGGAAGTGGCATCAGTGCCGGCCGAACCGCACGACGTCGCGCTGGATGCGGTATTGACGGAGAGCGGCTT
TCGACATTTCAAGGTGAAATGA

Upstream 100 bases:

>100_bases
TGGCGAAAAAAGGAGGCTGCATGGTTTCAGTCGAGCGCCATTTTGCATTATGGCATCCGGATCATTAAAAGCAGTTCGGT
CTGCCCGGAAGGATGGTTGG

Downstream 100 bases:

>100_bases
GGAAATTCGCGCGGACTCCGTCGCGTCCTCGAATTGAATCATTGGAACCGACCACGTGCGTGATTTGGCGTCATCCAGAT
TGTCGTGGTCCAAACGGGAT

Product: 5-formyltetrahydrofolate cyclo-ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 192

Protein sequence:

>193_residues
MSPKDLKAALRKERLALRDAMPAEARIEASLAMADHASDVIALDPGHVVSGFWPIRTEADIRPLMVRLRDRGARLCLPVI
LDKKAIIFRELLDGIAVVETGFGTTGPGPDAPEVDPDIMLVPLSAFDAMGHRIGYGAGYYDRAIDRLRRKGHMPRLIGIA
FDCQEVASVPAEPHDVALDAVLTESGFRHFKVK

Sequences:

>Translated_193_residues
MSPKDLKAALRKERLALRDAMPAEARIEASLAMADHASDVIALDPGHVVSGFWPIRTEADIRPLMVRLRDRGARLCLPVI
LDKKAIIFRELLDGIAVVETGFGTTGPGPDAPEVDPDIMLVPLSAFDAMGHRIGYGAGYYDRAIDRLRRKGHMPRLIGIA
FDCQEVASVPAEPHDVALDAVLTESGFRHFKVK
>Mature_192_residues
SPKDLKAALRKERLALRDAMPAEARIEASLAMADHASDVIALDPGHVVSGFWPIRTEADIRPLMVRLRDRGARLCLPVIL
DKKAIIFRELLDGIAVVETGFGTTGPGPDAPEVDPDIMLVPLSAFDAMGHRIGYGAGYYDRAIDRLRRKGHMPRLIGIAF
DCQEVASVPAEPHDVALDAVLTESGFRHFKVK

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Escherichia coli, GI1789278, Length=182, Percent_Identity=31.3186813186813, Blast_Score=80, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: NA

Molecular weight: Translated: 21116; Mature: 20985

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPKDLKAALRKERLALRDAMPAEARIEASLAMADHASDVIALDPGHVVSGFWPIRTEAD
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEECCCCEEECEECCCCCCC
IRPLMVRLRDRGARLCLPVILDKKAIIFRELLDGIAVVETGFGTTGPGPDAPEVDPDIML
HHHHHHHHHHCCCEEEEHHHHCCHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCEEE
VPLSAFDAMGHRIGYGAGYYDRAIDRLRRKGHMPRLIGIAFDCQEVASVPAEPHDVALDA
EEHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEEECHHHHHHCCCCCHHHHHHH
VLTESGFRHFKVK
HHHHCCCEEEECC
>Mature Secondary Structure 
SPKDLKAALRKERLALRDAMPAEARIEASLAMADHASDVIALDPGHVVSGFWPIRTEAD
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEECCCCEEECEECCCCCCC
IRPLMVRLRDRGARLCLPVILDKKAIIFRELLDGIAVVETGFGTTGPGPDAPEVDPDIML
HHHHHHHHHHCCCEEEEHHHHCCHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCEEE
VPLSAFDAMGHRIGYGAGYYDRAIDRLRRKGHMPRLIGIAFDCQEVASVPAEPHDVALDA
EEHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEEECHHHHHHCCCCCHHHHHHH
VLTESGFRHFKVK
HHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]