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The map label for this gene is ykoU [H]

Identifier: 150397829

GI number: 150397829

Start: 2731583

End: 2734180

Strand: Direct

Name: ykoU [H]

Synonym: Smed_2631

Alternate gene names: 150397829

Gene position: 2731583-2734180 (Clockwise)

Preceding gene: 150397815

Following gene: 150397831

Centisome position: 72.23

GC content: 62.16

Gene sequence:

>2598_bases
ATGGCCGCTCGCAACGAAACACTTACCGAATATAACAGGCGCCGTGACTTCACGCGGACGAAGGAGCCCAAGGGAACCGT
CGCTCGTCGCAGCGGGAACAGGATGCGGTTCCTGGTCCAGAAGCACGCCGCAACCCGCCTGCATTACGACTTTCGCCTGG
AATGGGAGGGCGTGCTGAAGAGCTGGGCGGTGACGCGCGGCCCAAGCCTCAACCCCGAGGACAAGCGCCTTGCCGTCCGC
ACCGAAGACCACCCGCTTGCTTATGGCGACTTCGAAGGAACCATCCCGAAGGGAGAATATGGCGGCGGCACCGTGATGCT
CTGGGATACGGGCTGGTGGGAGCCGGAGGATGACCCGTCCAAAGCCTTGAGGAAGGGCAAGCTCTCCTTCAAGCTGCATG
GCAGCCGCATGAAGGGAGGCTGGGCTCTGGTACGCATGCGCCCACGCGAAGGCGAGAAGCGCGAGAACTGGCTGCTCGTC
AAGGAAACGGATGAGATCGCCTCCAAGGATGGCGAGAGCCTGATCAACGAAAACATCACCAGCGTCGTCACCGGTCGCAC
CATGGAAGAGATCGCCGAAGGCAGGGGCGAAAAGCGCTCACGCGTCTGGCACTCGAACAAAAGCACGGCGGCCAATCTCA
GGGCCGGCGCGGTCGCTGAAGACGGCAATGCACGCAAGCGCCCCACGCGAAAGCCCTCAGGCAAACTGCCTACCTTCCGG
GCGCCTCAGCTGGCGACGCTGGTGACCCAGGTACCCGTGGGCGACGCGTGGCTGAACGAAGCCAAGTTCGACGGCTACCG
GCTTGTTTGCGCCCTGGGCGGCGGTACTGCCCGCTGCTACACGCGCAACGGACTCGATTGGACCGAAAAGTTCCCGGTCA
TTGCCGCAGCCCTTGCCGAACTCGACTGCCGGTCCGCCCTTATCGACGGCGAAGTCGTAGCACTGTCAGAAGGCGGGTCC
ACTTTCTCCGCCCTGCAGAAAGCGCTTGCAACAGGGGCCAGCACACGGCTTTACGCGTTCGATCTCATCGAGCTCGACGG
CAAGGATTTGAGCAGAAAGCCGCTCGTGGAGCGCAAGGAAAAGCTCGAAGCGCTGCTCCAAACGCTGGGCACGACCTCGA
CCATCCAGTTCAGCGAGCATGTTCGCGGGAATGGCGAGCACGTGCTTGCCGCCATATGCAAGGCTGGTCAGGAGGGTATA
ATCGCCAAGGAGGCGAACGCCCCCTACCGGAGCGGGCGCACCCGAAGCTGGCTCAAGGTGAAATGCACCAAACGCCAGGA
ATTCGTCATCGGCGGCTACAGCCTGTCGGACAAGAAGGGGCGCGCCTTCGCCTCGCTCATCGTCGGGACTTTCGAAGGCG
GGAAGCTGATCTATCGTGGCGGGGTCGGAACCGGTTTCAGCAAAAAGACGATGGAGGACCTCGCCGCAGCCTTCGCCTCA
CGCAAAAGAGAAACGTCGCCCTTCGACAGCATACCGCGAGAGAGAATGCGACATTCAGTTTGGCTGAAGCCGGACCTGGT
GGCCGAGGTAGACTTCGCCGAATTCACGGCTGAAGGCCATATCCGCCACGGTTCGTTCGAGGGATTGCGCGAGGACAAGG
AGGCAAAGGCCGTGAAACTGGAGACATCGAAGCCAGCGGAAGTGGAGTCCGGGACCACCACCAAGGGTAAATCCACCACA
AAGGCGCGCAGGACATCGGCCGCACAAGGTGACGCCGACGTCCTCGGCATCCGTATTTCGCATCCGGACCGCGTCCTGTT
CAAAGGTCAGGGCATCACCAAGATCGATCTTGCCCGCTATTATGCAATCGTCGCCGACAGGATGCTCCCCTTTGCCGCCG
ACCATCCCGTCTCGCTGGTGCGCTGCCCGCAGGGCGGCGAGCGGCAGTGCTTCTTCCAGAAGCACGCAAGCGACGGCTTT
CCCGATGCGATCAGGGAAGTGCCCATCACCGAATCGTCGGGAGACACCGAAGACTACATGTATATCCACGATGCCAAGGG
GCTCGTCGCAGCAGTACAGATGGGGACGCTCGAATTTCACATCTGGGGCGCAAGGACCGATCGGCTGGAGAAACCCGATC
GGCTGGTCTTCGATCTCGACCCCGATCCAAGCGTCGACTTCGCAACCGTCAAAGCAGCGGCCGTAGAGCTTCGCGACGAG
CTCGCCGGGATCGGCCTGAAAACCGTGCCGATGGTGACGGGCGGCAAGGGAGTCCACGTGATCGTGCCGCTCCGCCCCCA
TGCCGAATGGGATGAAGTAAAAGGGTTCGCCAAGGCGCTCGCGCAATCTTTTGCCGAGCGCGATCCGGATCATTTCGTCG
CGACCATGTCCAAGGCCAAGCGCAAGGGGAGGATTTTCATCGACTGGCTGCGCAACGACCGCGGCGCCACGGCGATAGCC
CCCTACTCCACCCGTGCGCGCGCCGGCGGACCGGTCGCCACTCCGGTCGGCTGGGAGGAGCTTGAAAGCCTCGATGCCGC
CAATGGGTTTCATATTCCCGAAATTCTCGCACGCATCGAGGCCGGAACCGATCCCTGGCGGGACATCGGCAAGATCAGTC
AGTCGCTGACGAAGAAGATCCTGAACTCGGTCGCGTGA

Upstream 100 bases:

>100_bases
CTACCCCTGGAAATATGAAGCCTGCACGGCCCGCTATTGCCCTGATCGACGGCGCCTCGACGGCGCGAAAGCTGCTCTCG
GGTGAGGTGCGTTTAGGACC

Downstream 100 bases:

>100_bases
GGCCGCCTCTCGCCTGGTCTGCCTGAGCCCTGGATCACGATGATATCACTCGGGTCGAACGTGATCGATTTGAAAGAATA
GAGCGGGGTGCGGGCGGAAA

Product: DNA ligase D

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 865; Mature: 864

Protein sequence:

>865_residues
MAARNETLTEYNRRRDFTRTKEPKGTVARRSGNRMRFLVQKHAATRLHYDFRLEWEGVLKSWAVTRGPSLNPEDKRLAVR
TEDHPLAYGDFEGTIPKGEYGGGTVMLWDTGWWEPEDDPSKALRKGKLSFKLHGSRMKGGWALVRMRPREGEKRENWLLV
KETDEIASKDGESLINENITSVVTGRTMEEIAEGRGEKRSRVWHSNKSTAANLRAGAVAEDGNARKRPTRKPSGKLPTFR
APQLATLVTQVPVGDAWLNEAKFDGYRLVCALGGGTARCYTRNGLDWTEKFPVIAAALAELDCRSALIDGEVVALSEGGS
TFSALQKALATGASTRLYAFDLIELDGKDLSRKPLVERKEKLEALLQTLGTTSTIQFSEHVRGNGEHVLAAICKAGQEGI
IAKEANAPYRSGRTRSWLKVKCTKRQEFVIGGYSLSDKKGRAFASLIVGTFEGGKLIYRGGVGTGFSKKTMEDLAAAFAS
RKRETSPFDSIPRERMRHSVWLKPDLVAEVDFAEFTAEGHIRHGSFEGLREDKEAKAVKLETSKPAEVESGTTTKGKSTT
KARRTSAAQGDADVLGIRISHPDRVLFKGQGITKIDLARYYAIVADRMLPFAADHPVSLVRCPQGGERQCFFQKHASDGF
PDAIREVPITESSGDTEDYMYIHDAKGLVAAVQMGTLEFHIWGARTDRLEKPDRLVFDLDPDPSVDFATVKAAAVELRDE
LAGIGLKTVPMVTGGKGVHVIVPLRPHAEWDEVKGFAKALAQSFAERDPDHFVATMSKAKRKGRIFIDWLRNDRGATAIA
PYSTRARAGGPVATPVGWEELESLDAANGFHIPEILARIEAGTDPWRDIGKISQSLTKKILNSVA

Sequences:

>Translated_865_residues
MAARNETLTEYNRRRDFTRTKEPKGTVARRSGNRMRFLVQKHAATRLHYDFRLEWEGVLKSWAVTRGPSLNPEDKRLAVR
TEDHPLAYGDFEGTIPKGEYGGGTVMLWDTGWWEPEDDPSKALRKGKLSFKLHGSRMKGGWALVRMRPREGEKRENWLLV
KETDEIASKDGESLINENITSVVTGRTMEEIAEGRGEKRSRVWHSNKSTAANLRAGAVAEDGNARKRPTRKPSGKLPTFR
APQLATLVTQVPVGDAWLNEAKFDGYRLVCALGGGTARCYTRNGLDWTEKFPVIAAALAELDCRSALIDGEVVALSEGGS
TFSALQKALATGASTRLYAFDLIELDGKDLSRKPLVERKEKLEALLQTLGTTSTIQFSEHVRGNGEHVLAAICKAGQEGI
IAKEANAPYRSGRTRSWLKVKCTKRQEFVIGGYSLSDKKGRAFASLIVGTFEGGKLIYRGGVGTGFSKKTMEDLAAAFAS
RKRETSPFDSIPRERMRHSVWLKPDLVAEVDFAEFTAEGHIRHGSFEGLREDKEAKAVKLETSKPAEVESGTTTKGKSTT
KARRTSAAQGDADVLGIRISHPDRVLFKGQGITKIDLARYYAIVADRMLPFAADHPVSLVRCPQGGERQCFFQKHASDGF
PDAIREVPITESSGDTEDYMYIHDAKGLVAAVQMGTLEFHIWGARTDRLEKPDRLVFDLDPDPSVDFATVKAAAVELRDE
LAGIGLKTVPMVTGGKGVHVIVPLRPHAEWDEVKGFAKALAQSFAERDPDHFVATMSKAKRKGRIFIDWLRNDRGATAIA
PYSTRARAGGPVATPVGWEELESLDAANGFHIPEILARIEAGTDPWRDIGKISQSLTKKILNSVA
>Mature_864_residues
AARNETLTEYNRRRDFTRTKEPKGTVARRSGNRMRFLVQKHAATRLHYDFRLEWEGVLKSWAVTRGPSLNPEDKRLAVRT
EDHPLAYGDFEGTIPKGEYGGGTVMLWDTGWWEPEDDPSKALRKGKLSFKLHGSRMKGGWALVRMRPREGEKRENWLLVK
ETDEIASKDGESLINENITSVVTGRTMEEIAEGRGEKRSRVWHSNKSTAANLRAGAVAEDGNARKRPTRKPSGKLPTFRA
PQLATLVTQVPVGDAWLNEAKFDGYRLVCALGGGTARCYTRNGLDWTEKFPVIAAALAELDCRSALIDGEVVALSEGGST
FSALQKALATGASTRLYAFDLIELDGKDLSRKPLVERKEKLEALLQTLGTTSTIQFSEHVRGNGEHVLAAICKAGQEGII
AKEANAPYRSGRTRSWLKVKCTKRQEFVIGGYSLSDKKGRAFASLIVGTFEGGKLIYRGGVGTGFSKKTMEDLAAAFASR
KRETSPFDSIPRERMRHSVWLKPDLVAEVDFAEFTAEGHIRHGSFEGLREDKEAKAVKLETSKPAEVESGTTTKGKSTTK
ARRTSAAQGDADVLGIRISHPDRVLFKGQGITKIDLARYYAIVADRMLPFAADHPVSLVRCPQGGERQCFFQKHASDGFP
DAIREVPITESSGDTEDYMYIHDAKGLVAAVQMGTLEFHIWGARTDRLEKPDRLVFDLDPDPSVDFATVKAAAVELRDEL
AGIGLKTVPMVTGGKGVHVIVPLRPHAEWDEVKGFAKALAQSFAERDPDHFVATMSKAKRKGRIFIDWLRNDRGATAIAP
YSTRARAGGPVATPVGWEELESLDAANGFHIPEILARIEAGTDPWRDIGKISQSLTKKILNSVA

Specific function: Probably involved in the repair of DNA double-strand breaks by non-homologous-end joining (NHEJ) during spore germination [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

Organism=Drosophila melanogaster, GI85815841, Length=386, Percent_Identity=24.3523316062176, Blast_Score=67, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012310
- InterPro:   IPR014146
- InterPro:   IPR014145
- InterPro:   IPR014143 [H]

Pfam domain/function: PF01068 DNA_ligase_A_M [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 95410; Mature: 95279

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAARNETLTEYNRRRDFTRTKEPKGTVARRSGNRMRFLVQKHAATRLHYDFRLEWEGVLK
CCCCCCHHHHHHHHCCCCCCCCCCCCHHHCCCCCEEEEEEHHHHHEEEEEEEEEHHHHHH
SWAVTRGPSLNPEDKRLAVRTEDHPLAYGDFEGTIPKGEYGGGTVMLWDTGWWEPEDDPS
HHHHCCCCCCCCCCCEEEEEECCCCEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCHH
KALRKGKLSFKLHGSRMKGGWALVRMRPREGEKRENWLLVKETDEIASKDGESLINENIT
HHHHCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCEEEEEECHHHHCCCCHHHHHCCHH
SVVTGRTMEEIAEGRGEKRSRVWHSNKSTAANLRAGAVAEDGNARKRPTRKPSGKLPTFR
HHHCCCHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCC
APQLATLVTQVPVGDAWLNEAKFDGYRLVCALGGGTARCYTRNGLDWTEKFPVIAAALAE
CCHHHHHHHHCCCCHHHHCCCCCCCEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHH
LDCRSALIDGEVVALSEGGSTFSALQKALATGASTRLYAFDLIELDGKDLSRKPLVERKE
HHHHHHEECCCEEEEECCCCHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCHHHHHH
KLEALLQTLGTTSTIQFSEHVRGNGEHVLAAICKAGQEGIIAKEANAPYRSGRTRSWLKV
HHHHHHHHHCCCCEEEEHHHHCCCCCHHHHHHHHCCCCCCEEECCCCCCCCCCCCCEEEE
KCTKRQEFVIGGYSLSDKKGRAFASLIVGTFEGGKLIYRGGVGTGFSKKTMEDLAAAFAS
EECCCCEEEEECEEECCCCCCEEEEHEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHH
RKRETSPFDSIPRERMRHSVWLKPDLVAEVDFAEFTAEGHIRHGSFEGLREDKEAKAVKL
CCCCCCCHHCCCHHHHHHCCCCCCCCEEECCHHHHCCCCCEECCCCCCCCCCCCCCEEEE
ETSKPAEVESGTTTKGKSTTKARRTSAAQGDADVLGIRISHPDRVLFKGQGITKIDLARY
ECCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCEEEEEEECCCCEEEEECCCCCCHHHHHH
YAIVADRMLPFAADHPVSLVRCPQGGERQCFFQKHASDGFPDAIREVPITESSGDTEDYM
HHHHHHHHCCCCCCCCCEEEECCCCCCCCCHHHHHCCCCCCHHHHCCCCCCCCCCCCCEE
YIHDAKGLVAAVQMGTLEFHIWGARTDRLEKPDRLVFDLDPDPSVDFATVKAAAVELRDE
EEECCCCEEEEEEECEEEEEEECCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHH
LAGIGLKTVPMVTGGKGVHVIVPLRPHAEWDEVKGFAKALAQSFAERDPDHFVATMSKAK
HHCCCCEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
RKGRIFIDWLRNDRGATAIAPYSTRARAGGPVATPVGWEELESLDAANGFHIPEILARIE
HCCCEEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHH
AGTDPWRDIGKISQSLTKKILNSVA
CCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AARNETLTEYNRRRDFTRTKEPKGTVARRSGNRMRFLVQKHAATRLHYDFRLEWEGVLK
CCCCCHHHHHHHHCCCCCCCCCCCCHHHCCCCCEEEEEEHHHHHEEEEEEEEEHHHHHH
SWAVTRGPSLNPEDKRLAVRTEDHPLAYGDFEGTIPKGEYGGGTVMLWDTGWWEPEDDPS
HHHHCCCCCCCCCCCEEEEEECCCCEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCHH
KALRKGKLSFKLHGSRMKGGWALVRMRPREGEKRENWLLVKETDEIASKDGESLINENIT
HHHHCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCEEEEEECHHHHCCCCHHHHHCCHH
SVVTGRTMEEIAEGRGEKRSRVWHSNKSTAANLRAGAVAEDGNARKRPTRKPSGKLPTFR
HHHCCCHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCC
APQLATLVTQVPVGDAWLNEAKFDGYRLVCALGGGTARCYTRNGLDWTEKFPVIAAALAE
CCHHHHHHHHCCCCHHHHCCCCCCCEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHH
LDCRSALIDGEVVALSEGGSTFSALQKALATGASTRLYAFDLIELDGKDLSRKPLVERKE
HHHHHHEECCCEEEEECCCCHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCHHHHHH
KLEALLQTLGTTSTIQFSEHVRGNGEHVLAAICKAGQEGIIAKEANAPYRSGRTRSWLKV
HHHHHHHHHCCCCEEEEHHHHCCCCCHHHHHHHHCCCCCCEEECCCCCCCCCCCCCEEEE
KCTKRQEFVIGGYSLSDKKGRAFASLIVGTFEGGKLIYRGGVGTGFSKKTMEDLAAAFAS
EECCCCEEEEECEEECCCCCCEEEEHEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHH
RKRETSPFDSIPRERMRHSVWLKPDLVAEVDFAEFTAEGHIRHGSFEGLREDKEAKAVKL
CCCCCCCHHCCCHHHHHHCCCCCCCCEEECCHHHHCCCCCEECCCCCCCCCCCCCCEEEE
ETSKPAEVESGTTTKGKSTTKARRTSAAQGDADVLGIRISHPDRVLFKGQGITKIDLARY
ECCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCEEEEEEECCCCEEEEECCCCCCHHHHHH
YAIVADRMLPFAADHPVSLVRCPQGGERQCFFQKHASDGFPDAIREVPITESSGDTEDYM
HHHHHHHHCCCCCCCCCEEEECCCCCCCCCHHHHHCCCCCCHHHHCCCCCCCCCCCCCEE
YIHDAKGLVAAVQMGTLEFHIWGARTDRLEKPDRLVFDLDPDPSVDFATVKAAAVELRDE
EEECCCCEEEEEEECEEEEEEECCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHH
LAGIGLKTVPMVTGGKGVHVIVPLRPHAEWDEVKGFAKALAQSFAERDPDHFVATMSKAK
HHCCCCEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
RKGRIFIDWLRNDRGATAIAPYSTRARAGGPVATPVGWEELESLDAANGFHIPEILARIE
HCCCEEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHH
AGTDPWRDIGKISQSLTKKILNSVA
CCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]