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The map label for this gene is glmM

Identifier: 150397820

GI number: 150397820

Start: 2720203

End: 2721558

Strand: Reverse

Name: glmM

Synonym: Smed_2622

Alternate gene names: 150397820

Gene position: 2721558-2720203 (Counterclockwise)

Preceding gene: 150397821

Following gene: 150397819

Centisome position: 71.96

GC content: 62.39

Gene sequence:

>1356_bases
ATGAAGCGCAAATATTTCGGCACCGATGGTATTCGCGGCCAATCCAATATATTTCCGATGACGCCGGACCTCGCGATGCG
GGTCGGTATTGCAGTAGGAACCATTTTCAGAAACGGAGCTCACCGCCACCGCGTGGTGATCGGCAAGGACACGCGTCTTT
CCGGCTACATGCTTGAAAATGCGATGGTCGCCGGATTCACGGCGGCCGGGCTCGACGTGTTTCTCCTCGGTCCGATCCCG
ACGCCCGGCGTCGCCATGCTGACCCGTTCGCTGAGGGCTGATATCGGCGTGATGATCTCGGCCTCTCACAACGCGTTCCG
CGACAACGGCATCAAGCTCTTCGGACCCGATGGCTACAAGCTTTCCGACGACATCGAGGAAAAGATCGAGGAACTGCTGG
ATCAGGACATGACCCGCCAGCTTGCAAAACCGGAGGACATCGGCCGGGCGAAGCGGGTCGACGGCGACATCTATCGCTAT
ATCGAGCAGGCCAAGCGGACGCTGCCGCGCGACGTTACGCTGACAGGGCTCAGAATCGCGATCGATTGCGCCAACGGTGC
CGCCTACAAGGTCGCCCCCTCCGCCCTTTGGGAGCTCGGCGCCGAGGTCGTTCCCATCGGGACCGAACCCAATGGCGTCA
ACATCAATCTCGAATGCGGGTCGACGCATCCGGCCGCGCTGCAGAAGAAGGTGCACGAGGTGAGGGCGGACATCGGCATC
GCGCTCGATGGAGATGCCGACCGTGTATTGATCATCGATGAAGAGGGCCAGGTCATCGATGGAGACCAGCTCATGGCGGT
GATCGCCGACAGTTGGGCAGCCGACGGCATGCTCAAGGGTGGCGGCATTGCCGCGACCGTCATGTCGAATCTCGGTCTCG
AACGCTACCTCCAGGCGCGTCGGCTCAAACTCCACCGCACCAAGGTCGGCGACCGCTACGTCGTCGAGCAGATGCGCCAG
GACGGCCTGAACGTCGGTGGCGAACAGTCCGGCCATATCGTGCTTTCCGACTTCGGAACGACGGGTGACGGGCTTGTCGC
GGCTCTGCAGATCCTTGCAGTCGTCAAACGCCAGGGCAAGACGGTGAGCGAGATATGCCGCCGTTTCGAGCCGGTGCCGC
AGGTCCTGAAAAACGTGCGGATTTCGGCAGGAAAGCCGCTGGAAGATGCCGGGGTCAAGCAGGCGATTGCCGATGCGGAG
GCGCAGCTCGCCAAGAACGGGCGGCTGCTCATCCGTCCCTCCGGCACCGAACCGCTGATCCGCGTCATGGCGGAAGGCGA
CGATCGCGGAAAGGTCGAGCGCATCGTCGACGAACTTGTCAGCGTGATCGGCGCCGTACGCAACGCCGCTGCCTGA

Upstream 100 bases:

>100_bases
CTGCAGGCGGGGTCGCGGGATGATGAAGGCCAATCGGGGAACACGCAGGCAGACGCGGCCGGGGCAAGCGGCGACGCCCA
AAGAGGACAATGGAGTTTCT

Downstream 100 bases:

>100_bases
GCTTGGAAAGAAAGCGCAGCTTCGGGCTCTCATCCGCCGGCGGGGAGGTGCAGGCGGATGAGGGGCAAGCACTGCACGTG
AATACAAGCGAGCTAATACT

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MKRKYFGTDGIRGQSNIFPMTPDLAMRVGIAVGTIFRNGAHRHRVVIGKDTRLSGYMLENAMVAGFTAAGLDVFLLGPIP
TPGVAMLTRSLRADIGVMISASHNAFRDNGIKLFGPDGYKLSDDIEEKIEELLDQDMTRQLAKPEDIGRAKRVDGDIYRY
IEQAKRTLPRDVTLTGLRIAIDCANGAAYKVAPSALWELGAEVVPIGTEPNGVNINLECGSTHPAALQKKVHEVRADIGI
ALDGDADRVLIIDEEGQVIDGDQLMAVIADSWAADGMLKGGGIAATVMSNLGLERYLQARRLKLHRTKVGDRYVVEQMRQ
DGLNVGGEQSGHIVLSDFGTTGDGLVAALQILAVVKRQGKTVSEICRRFEPVPQVLKNVRISAGKPLEDAGVKQAIADAE
AQLAKNGRLLIRPSGTEPLIRVMAEGDDRGKVERIVDELVSVIGAVRNAAA

Sequences:

>Translated_451_residues
MKRKYFGTDGIRGQSNIFPMTPDLAMRVGIAVGTIFRNGAHRHRVVIGKDTRLSGYMLENAMVAGFTAAGLDVFLLGPIP
TPGVAMLTRSLRADIGVMISASHNAFRDNGIKLFGPDGYKLSDDIEEKIEELLDQDMTRQLAKPEDIGRAKRVDGDIYRY
IEQAKRTLPRDVTLTGLRIAIDCANGAAYKVAPSALWELGAEVVPIGTEPNGVNINLECGSTHPAALQKKVHEVRADIGI
ALDGDADRVLIIDEEGQVIDGDQLMAVIADSWAADGMLKGGGIAATVMSNLGLERYLQARRLKLHRTKVGDRYVVEQMRQ
DGLNVGGEQSGHIVLSDFGTTGDGLVAALQILAVVKRQGKTVSEICRRFEPVPQVLKNVRISAGKPLEDAGVKQAIADAE
AQLAKNGRLLIRPSGTEPLIRVMAEGDDRGKVERIVDELVSVIGAVRNAAA
>Mature_451_residues
MKRKYFGTDGIRGQSNIFPMTPDLAMRVGIAVGTIFRNGAHRHRVVIGKDTRLSGYMLENAMVAGFTAAGLDVFLLGPIP
TPGVAMLTRSLRADIGVMISASHNAFRDNGIKLFGPDGYKLSDDIEEKIEELLDQDMTRQLAKPEDIGRAKRVDGDIYRY
IEQAKRTLPRDVTLTGLRIAIDCANGAAYKVAPSALWELGAEVVPIGTEPNGVNINLECGSTHPAALQKKVHEVRADIGI
ALDGDADRVLIIDEEGQVIDGDQLMAVIADSWAADGMLKGGGIAATVMSNLGLERYLQARRLKLHRTKVGDRYVVEQMRQ
DGLNVGGEQSGHIVLSDFGTTGDGLVAALQILAVVKRQGKTVSEICRRFEPVPQVLKNVRISAGKPLEDAGVKQAIADAE
AQLAKNGRLLIRPSGTEPLIRVMAEGDDRGKVERIVDELVSVIGAVRNAAA

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=447, Percent_Identity=48.993288590604, Blast_Score=414, Evalue=1e-117,
Organism=Escherichia coli, GI1788361, Length=441, Percent_Identity=27.2108843537415, Blast_Score=111, Evalue=9e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_SINMW (A6UCS2)

Other databases:

- EMBL:   CP000738
- RefSeq:   YP_001328287.1
- ProteinModelPortal:   A6UCS2
- SMR:   A6UCS2
- STRING:   A6UCS2
- GeneID:   5323491
- GenomeReviews:   CP000738_GR
- KEGG:   smd:Smed_2622
- eggNOG:   COG1109
- HOGENOM:   HBG644964
- OMA:   VHDRYIE
- ProtClustDB:   PRK14315
- BioCyc:   SMED366394:SMED_2622-MONOMER
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 48597; Mature: 48597

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 102-102

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRKYFGTDGIRGQSNIFPMTPDLAMRVGIAVGTIFRNGAHRHRVVIGKDTRLSGYMLEN
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEECC
AMVAGFTAAGLDVFLLGPIPTPGVAMLTRSLRADIGVMISASHNAFRDNGIKLFGPDGYK
HHHCCEEECCCEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEECCCCCC
LSDDIEEKIEELLDQDMTRQLAKPEDIGRAKRVDGDIYRYIEQAKRTLPRDVTLTGLRIA
CCHHHHHHHHHHHHHHHHHHHCCCHHCCHHHCCCHHHHHHHHHHHHHCCCCEEEEEEEEE
IDCANGAAYKVAPSALWELGAEVVPIGTEPNGVNINLECGSTHPAALQKKVHEVRADIGI
EEECCCCEEEECHHHHHHCCCCEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCE
ALDGDADRVLIIDEEGQVIDGDQLMAVIADSWAADGMLKGGGIAATVMSNLGLERYLQAR
EEECCCCEEEEECCCCCEECCCCEEHHHHHHHHCCCEECCCCHHHHHHHHCCHHHHHHHH
RLKLHRTKVGDRYVVEQMRQDGLNVGGEQSGHIVLSDFGTTGDGLVAALQILAVVKRQGK
HHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCC
TVSEICRRFEPVPQVLKNVRISAGKPLEDAGVKQAIADAEAQLAKNGRLLIRPSGTEPLI
CHHHHHHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHH
RVMAEGDDRGKVERIVDELVSVIGAVRNAAA
HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKRKYFGTDGIRGQSNIFPMTPDLAMRVGIAVGTIFRNGAHRHRVVIGKDTRLSGYMLEN
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEECC
AMVAGFTAAGLDVFLLGPIPTPGVAMLTRSLRADIGVMISASHNAFRDNGIKLFGPDGYK
HHHCCEEECCCEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEECCCCCC
LSDDIEEKIEELLDQDMTRQLAKPEDIGRAKRVDGDIYRYIEQAKRTLPRDVTLTGLRIA
CCHHHHHHHHHHHHHHHHHHHCCCHHCCHHHCCCHHHHHHHHHHHHHCCCCEEEEEEEEE
IDCANGAAYKVAPSALWELGAEVVPIGTEPNGVNINLECGSTHPAALQKKVHEVRADIGI
EEECCCCEEEECHHHHHHCCCCEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCE
ALDGDADRVLIIDEEGQVIDGDQLMAVIADSWAADGMLKGGGIAATVMSNLGLERYLQAR
EEECCCCEEEEECCCCCEECCCCEEHHHHHHHHCCCEECCCCHHHHHHHHCCHHHHHHHH
RLKLHRTKVGDRYVVEQMRQDGLNVGGEQSGHIVLSDFGTTGDGLVAALQILAVVKRQGK
HHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCC
TVSEICRRFEPVPQVLKNVRISAGKPLEDAGVKQAIADAEAQLAKNGRLLIRPSGTEPLI
CHHHHHHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHH
RVMAEGDDRGKVERIVDELVSVIGAVRNAAA
HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA