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The map label for this gene is aroK [H]

Identifier: 150397763

GI number: 150397763

Start: 2662646

End: 2663224

Strand: Reverse

Name: aroK [H]

Synonym: Smed_2565

Alternate gene names: 150397763

Gene position: 2663224-2662646 (Counterclockwise)

Preceding gene: 150397769

Following gene: 150397762

Centisome position: 70.42

GC content: 62.18

Gene sequence:

>579_bases
ATGAACGATGTGACCGAACCGGTTTCCGCGACGCTGGTCGAAAGGGCCAAGCGCGCCCTCGGTAAGCGCAATCTCGTTTT
CATAGGCCTCATGGGGGCAGGTAAATCGGCAATCGGGCGTCTGACCGCGCAGGCGCTTGGCGTCCCCTTCGTCGATTCCG
ACCACGAGATAGAGCGCGTCTCGCGCATGACGATCAGCGATCTCTTCGCGACCTACGGCGAGGAAGAATTCCGGGCGCTC
GAGGCTCGCGTGCTGAAGCGCCTGCTCAGGTCGGGTCCTCGGGTGGTGTCGACCGGCGGCGGCGCCTATATCAACGAACG
CTCGCGGCGGCATATCAAAAGGGGCGGCCTGACGGTCTGGCTCAATGCCGAGCTCGACGTTCTCTGGGAGCGGGTGAACA
AACGCGACACCCGGCCGCTTCTGAAGACCGAGAACCCGAAGCAGACGCTCGAAAACCTGATGCGCGCGCGCTATCCGATC
TATGCCGAGGCGGATCTGACGGTCCTTTCGCGCGATGTGAAAAAAGAAGCGATGGTCGAGGAGGTTCTCGCCGCCATCGC
CGATCACCAGAAAGCATGA

Upstream 100 bases:

>100_bases
CCATGTCCCATTGATCGTCCGAGGTGGCCCCCAACGCCTGCGACTTGACGCTCCACCCCGATTTGTCGATACCGGGGGGG
AATGGGGAAATTGAAGTGCA

Downstream 100 bases:

>100_bases
AACCCATGACCAGCGATGTGATGCCAGCCGCCGAGCGTAAGGTCCGCGTCGATCTTGCGGAGCGTTCCTACGATATCCTC
ATCGGCCCCGGCCTGATCGC

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MNDVTEPVSATLVERAKRALGKRNLVFIGLMGAGKSAIGRLTAQALGVPFVDSDHEIERVSRMTISDLFATYGEEEFRAL
EARVLKRLLRSGPRVVSTGGGAYINERSRRHIKRGGLTVWLNAELDVLWERVNKRDTRPLLKTENPKQTLENLMRARYPI
YAEADLTVLSRDVKKEAMVEEVLAAIADHQKA

Sequences:

>Translated_192_residues
MNDVTEPVSATLVERAKRALGKRNLVFIGLMGAGKSAIGRLTAQALGVPFVDSDHEIERVSRMTISDLFATYGEEEFRAL
EARVLKRLLRSGPRVVSTGGGAYINERSRRHIKRGGLTVWLNAELDVLWERVNKRDTRPLLKTENPKQTLENLMRARYPI
YAEADLTVLSRDVKKEAMVEEVLAAIADHQKA
>Mature_192_residues
MNDVTEPVSATLVERAKRALGKRNLVFIGLMGAGKSAIGRLTAQALGVPFVDSDHEIERVSRMTISDLFATYGEEEFRAL
EARVLKRLLRSGPRVVSTGGGAYINERSRRHIKRGGLTVWLNAELDVLWERVNKRDTRPLLKTENPKQTLENLMRARYPI
YAEADLTVLSRDVKKEAMVEEVLAAIADHQKA

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Homo sapiens, GI153792148, Length=174, Percent_Identity=28.1609195402299, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI87082255, Length=164, Percent_Identity=35.9756097560976, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1786587, Length=167, Percent_Identity=26.9461077844311, Blast_Score=66, Evalue=1e-12,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 21525; Mature: 21525

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: PS00267 TACHYKININ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDVTEPVSATLVERAKRALGKRNLVFIGLMGAGKSAIGRLTAQALGVPFVDSDHEIERV
CCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCHHHHHH
SRMTISDLFATYGEEEFRALEARVLKRLLRSGPRVVSTGGGAYINERSRRHIKRGGLTVW
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCEEEE
LNAELDVLWERVNKRDTRPLLKTENPKQTLENLMRARYPIYAEADLTVLSRDVKKEAMVE
ECCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
EVLAAIADHQKA
HHHHHHHHCCCC
>Mature Secondary Structure
MNDVTEPVSATLVERAKRALGKRNLVFIGLMGAGKSAIGRLTAQALGVPFVDSDHEIERV
CCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCHHHHHH
SRMTISDLFATYGEEEFRALEARVLKRLLRSGPRVVSTGGGAYINERSRRHIKRGGLTVW
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCEEEE
LNAELDVLWERVNKRDTRPLLKTENPKQTLENLMRARYPIYAEADLTVLSRDVKKEAMVE
ECCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
EVLAAIADHQKA
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]