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The map label for this gene is yjiA [H]

Identifier: 150397769

GI number: 150397769

Start: 2667649

End: 2668797

Strand: Reverse

Name: yjiA [H]

Synonym: Smed_2571

Alternate gene names: 150397769

Gene position: 2668797-2667649 (Counterclockwise)

Preceding gene: 150397770

Following gene: 150397763

Centisome position: 70.57

GC content: 64.75

Gene sequence:

>1149_bases
ATGAATGGTCCAATGCCGGTGGTGCCGGTCTCGATCCTCACCGGCTTTCTCGGCGCGGGCAAGACGACCCTTCTGAACCG
GGTTCTCAAGGATCCGGCGCTTGCAGATACGGCCGTGATCATCAACGAGTTCGGCGACGTCTCGATCGACCACCTCCTCG
TCGAGGCATCAAGTGACGGCGTCATCGAGCTTTCCGACGGCTGCCTGTGCTGCACCGTTCGCGGTGAGCTTGTCGATACG
CTCGCCGATCTCATGGACCGGATGCAGACGGGCCGTATCAAGCCGTTGAAGCGCGTCGTCATCGAAACCACCGGGCTTGC
CGATCCGGCGCCGGTGCTGCAGTCCGTCCTCGGCAATCCCGTCATTGCCCAGAACTTCCGTCTGGACGGCGTCGTCACCG
TCGTCGATGCTGTCAACGGCGGGCAGACGATCGCCAATCATCCGGAGGCGCTGAAGCAGGTCGCCGTTGCCGACCGGCTG
GTGATCAGCAAGACCGGGCTCGCGAAAGGCAGAGGGCTCGGAGGGCTTAAGGCGCGACTGAGGGATCTCAACCCGCGCGC
GCCCGTCATCGACGGCGATACGGAGGAGGCGGGCCGGGCCGAACTCTTCGTCTGCGGCCTCTATGACGCCTCGACCAAGG
TCGCCGATGTCGGCCGCTGGCTCCAGGACGAGGCCGACGCCGATCATGGCCATCACCACCACCACGGCGCTGGTCACGAC
CATGGGGGCGGGCACCACCATCACGACCATCACCACGACGTCAATCGCCATGGCTCGGACATCCGCTCCTTCAGTATCGT
GCACGACCGGCCGATCGAGCCGATGGCGCTGGAGATGTTCATCGATCTTCTGCGATCGGCGCATGGCGAAAAGCTTCTCC
GCATGAAGGCGATCGTTTCTGTCGCCGACAATCCCGAGCGGCCGGTGGTACTGCACGGCGTGCAGGCGGTCTTTCACGCT
CCGGAGCGGCTTGCCGCCTGGCCTGACCCGGCCGATCGCCGCACGCGGATGGTGCTGATCACCAAAGGCCTGGAGGAAGC
GTTCGTGCGTGACCTTTTCGACGCCTTCACTGGCAAGCCGCGCATCGATCGGCCGGACGCACAGGCGCTCGCCGACAATC
CGCTGGCCGTACCGGGAATGACGTTCTGA

Upstream 100 bases:

>100_bases
CGCAAAGGCCGGCAAGAATGCCACGGCGCAGGGCGACGCCGTCGAGATCGCTGACGTGCCGATTCCGGTCCCGCGCCCGA
GCTTCTGAACGGAGTCTTTC

Downstream 100 bases:

>100_bases
GCCGCTGTCTTTCCGACCCATTCCCCTCCAGATCAGGGGCCATCGTCTGCGACGAGACGAACTGGAGCGCTAGGTCTTCT
TGCGGATGAGAAAGCGATGC

Product: cobalamin synthesis protein P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MNGPMPVVPVSILTGFLGAGKTTLLNRVLKDPALADTAVIINEFGDVSIDHLLVEASSDGVIELSDGCLCCTVRGELVDT
LADLMDRMQTGRIKPLKRVVIETTGLADPAPVLQSVLGNPVIAQNFRLDGVVTVVDAVNGGQTIANHPEALKQVAVADRL
VISKTGLAKGRGLGGLKARLRDLNPRAPVIDGDTEEAGRAELFVCGLYDASTKVADVGRWLQDEADADHGHHHHHGAGHD
HGGGHHHHDHHHDVNRHGSDIRSFSIVHDRPIEPMALEMFIDLLRSAHGEKLLRMKAIVSVADNPERPVVLHGVQAVFHA
PERLAAWPDPADRRTRMVLITKGLEEAFVRDLFDAFTGKPRIDRPDAQALADNPLAVPGMTF

Sequences:

>Translated_382_residues
MNGPMPVVPVSILTGFLGAGKTTLLNRVLKDPALADTAVIINEFGDVSIDHLLVEASSDGVIELSDGCLCCTVRGELVDT
LADLMDRMQTGRIKPLKRVVIETTGLADPAPVLQSVLGNPVIAQNFRLDGVVTVVDAVNGGQTIANHPEALKQVAVADRL
VISKTGLAKGRGLGGLKARLRDLNPRAPVIDGDTEEAGRAELFVCGLYDASTKVADVGRWLQDEADADHGHHHHHGAGHD
HGGGHHHHDHHHDVNRHGSDIRSFSIVHDRPIEPMALEMFIDLLRSAHGEKLLRMKAIVSVADNPERPVVLHGVQAVFHA
PERLAAWPDPADRRTRMVLITKGLEEAFVRDLFDAFTGKPRIDRPDAQALADNPLAVPGMTF
>Mature_382_residues
MNGPMPVVPVSILTGFLGAGKTTLLNRVLKDPALADTAVIINEFGDVSIDHLLVEASSDGVIELSDGCLCCTVRGELVDT
LADLMDRMQTGRIKPLKRVVIETTGLADPAPVLQSVLGNPVIAQNFRLDGVVTVVDAVNGGQTIANHPEALKQVAVADRL
VISKTGLAKGRGLGGLKARLRDLNPRAPVIDGDTEEAGRAELFVCGLYDASTKVADVGRWLQDEADADHGHHHHHGAGHD
HGGGHHHHDHHHDVNRHGSDIRSFSIVHDRPIEPMALEMFIDLLRSAHGEKLLRMKAIVSVADNPERPVVLHGVQAVFHA
PERLAAWPDPADRRTRMVLITKGLEEAFVRDLFDAFTGKPRIDRPDAQALADNPLAVPGMTF

Specific function: Binds GTP. May function as GTP-dependent regulator [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=369, Percent_Identity=27.6422764227642, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI126722884, Length=369, Percent_Identity=27.10027100271, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI148727351, Length=369, Percent_Identity=27.10027100271, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI146231952, Length=369, Percent_Identity=27.6422764227642, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI223941776, Length=359, Percent_Identity=26.1838440111421, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI223941779, Length=195, Percent_Identity=34.3589743589744, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI119120938, Length=138, Percent_Identity=37.6811594202899, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI87082430, Length=349, Percent_Identity=32.6647564469914, Blast_Score=138, Evalue=8e-34,
Organism=Escherichia coli, GI1788499, Length=159, Percent_Identity=34.5911949685535, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324356, Length=239, Percent_Identity=29.7071129707113, Blast_Score=100, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 41202; Mature: 41202

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGPMPVVPVSILTGFLGAGKTTLLNRVLKDPALADTAVIINEFGDVSIDHLLVEASSDG
CCCCCCEEHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEHEEEECCCCC
VIELSDGCLCCTVRGELVDTLADLMDRMQTGRIKPLKRVVIETTGLADPAPVLQSVLGNP
EEEECCCEEEEEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCC
VIAQNFRLDGVVTVVDAVNGGQTIANHPEALKQVAVADRLVISKTGLAKGRGLGGLKARL
EEECCCCCCCEEEEEECCCCCCCHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
RDLNPRAPVIDGDTEEAGRAELFVCGLYDASTKVADVGRWLQDEADADHGHHHHHGAGHD
HCCCCCCCEECCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCC
HGGGHHHHDHHHDVNRHGSDIRSFSIVHDRPIEPMALEMFIDLLRSAHGEKLLRMKAIVS
CCCCCCCCCCCCCHHCCCCCHHEEEEECCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHH
VADNPERPVVLHGVQAVFHAPERLAAWPDPADRRTRMVLITKGLEEAFVRDLFDAFTGKP
HCCCCCCCEEEHHHHHHHHCHHHHCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCC
RIDRPDAQALADNPLAVPGMTF
CCCCCCHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNGPMPVVPVSILTGFLGAGKTTLLNRVLKDPALADTAVIINEFGDVSIDHLLVEASSDG
CCCCCCEEHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEHEEEECCCCC
VIELSDGCLCCTVRGELVDTLADLMDRMQTGRIKPLKRVVIETTGLADPAPVLQSVLGNP
EEEECCCEEEEEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCC
VIAQNFRLDGVVTVVDAVNGGQTIANHPEALKQVAVADRLVISKTGLAKGRGLGGLKARL
EEECCCCCCCEEEEEECCCCCCCHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
RDLNPRAPVIDGDTEEAGRAELFVCGLYDASTKVADVGRWLQDEADADHGHHHHHGAGHD
HCCCCCCCEECCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCC
HGGGHHHHDHHHDVNRHGSDIRSFSIVHDRPIEPMALEMFIDLLRSAHGEKLLRMKAIVS
CCCCCCCCCCCCCHHCCCCCHHEEEEECCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHH
VADNPERPVVLHGVQAVFHAPERLAAWPDPADRRTRMVLITKGLEEAFVRDLFDAFTGKP
HCCCCCCCEEEHHHHHHHHCHHHHCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCC
RIDRPDAQALADNPLAVPGMTF
CCCCCCHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 1650347 [H]