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The map label for this gene is cobS [H]

Identifier: 150397758

GI number: 150397758

Start: 2658056

End: 2659051

Strand: Reverse

Name: cobS [H]

Synonym: Smed_2560

Alternate gene names: 150397758

Gene position: 2659051-2658056 (Counterclockwise)

Preceding gene: 150397759

Following gene: 150397757

Centisome position: 70.31

GC content: 60.54

Gene sequence:

>996_bases
ATGAGCAAGATTGACCTCGACATTTCCAACCTTCCCGACACGACCGTCTCGGTCCGGGAGGTTTTCGGCATCGACACCGA
TTTGCGCGTTCCGGCCTATTCGAAGGGCGATGCGTATGTACCCGATATCGATCAGGACTATCTCTTCGACCGTGATACGA
CGCTCGCCATTCTTGCCGGCTTCGCCCACAACCGGCGCGTGATGGTCTCGGGCTACCATGGCACCGGTAAATCGACCCAT
ATCGAGCAGGTAGCGGCGCGTCTCAACTGGCCATGCGTGCGCGTCAATCTCGACAGTCATGTGAGCCGCATCGATCTCGT
CGGAAAGGACGCCATCGTCGTCAAGGACGGGCTTCAGGTCACCGAGTTCAAGGACGGGATACTGCCCTGGGCCTATCAAC
ACAATGTCGCGCTCGTCTTCGACGAATATGATGCCGGCCGCCCGGACGTGATGTTCGTCATTCAGCGCGTGCTCGAGGCC
TCCGGCCGCCTGACGCTGCTCGACCAGAGCCGCGTCATCCGTCCGCATCCGGCCTTCCGTCTGTTTGCGACCGCCAATAC
CGTCGGCCTCGGCGACACGACCGGTCTCTATCACGGTACCCAGCAGATCAACCAGGCCCAGATGGACCGCTGGTCGATCG
TGACGACGCTCAACTATTTGCCGCACGACAAGGAAGTCGACATCGTTGCCGCCAAGGTCAAGGGTTTCACTGCCGACAAG
GGGCGCGAGACCGTGTCGAAGATGGTTCGTGTGGCCGACCTGACGCGTGCCGCCTTCATCAATGGCGACCTGTCGACGGT
CATGAGCCCTCGTACCGTCATCACCTGGGCCGAAAATGCCTATATCTTCGGCGACATCGCCTTCGCCTTCCGCGTGACGT
TCCTCAACAAGTGCGACGAACTGGAGCGGGCGCTGGTCGCCGAGCATTATCAGCGCGCTTTCGGCGTCGAACTCAAGGAG
AGCGCTGCCAATATCGTGCTGGAAGCGACCGCCTGA

Upstream 100 bases:

>100_bases
GTTAAAACAGGCTGGTTTCTGCTAACAACGCGGATTATGACAGAAGCACAGTTTGCAGGCGAATGCGCGGGTGCCGTCCG
GCGGCCGCTCTGGAGTTATG

Downstream 100 bases:

>100_bases
GCCTTCAAGCGCCGGTTTCCGTGAGAAGCCGGACTGCTTCCCTGGAGCGGGAGGGATTGTTTTTTATGCAGATTCCGCTC
CTATCATTATAGTCGATGTG

Product: cobalt chelatase, pCobS small subunit

Products: NA

Alternate protein names: Hydrogenobyrinic acid a,c-diamide cobaltochelatase subunit CobS [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MSKIDLDISNLPDTTVSVREVFGIDTDLRVPAYSKGDAYVPDIDQDYLFDRDTTLAILAGFAHNRRVMVSGYHGTGKSTH
IEQVAARLNWPCVRVNLDSHVSRIDLVGKDAIVVKDGLQVTEFKDGILPWAYQHNVALVFDEYDAGRPDVMFVIQRVLEA
SGRLTLLDQSRVIRPHPAFRLFATANTVGLGDTTGLYHGTQQINQAQMDRWSIVTTLNYLPHDKEVDIVAAKVKGFTADK
GRETVSKMVRVADLTRAAFINGDLSTVMSPRTVITWAENAYIFGDIAFAFRVTFLNKCDELERALVAEHYQRAFGVELKE
SAANIVLEATA

Sequences:

>Translated_331_residues
MSKIDLDISNLPDTTVSVREVFGIDTDLRVPAYSKGDAYVPDIDQDYLFDRDTTLAILAGFAHNRRVMVSGYHGTGKSTH
IEQVAARLNWPCVRVNLDSHVSRIDLVGKDAIVVKDGLQVTEFKDGILPWAYQHNVALVFDEYDAGRPDVMFVIQRVLEA
SGRLTLLDQSRVIRPHPAFRLFATANTVGLGDTTGLYHGTQQINQAQMDRWSIVTTLNYLPHDKEVDIVAAKVKGFTADK
GRETVSKMVRVADLTRAAFINGDLSTVMSPRTVITWAENAYIFGDIAFAFRVTFLNKCDELERALVAEHYQRAFGVELKE
SAANIVLEATA
>Mature_330_residues
SKIDLDISNLPDTTVSVREVFGIDTDLRVPAYSKGDAYVPDIDQDYLFDRDTTLAILAGFAHNRRVMVSGYHGTGKSTHI
EQVAARLNWPCVRVNLDSHVSRIDLVGKDAIVVKDGLQVTEFKDGILPWAYQHNVALVFDEYDAGRPDVMFVIQRVLEAS
GRLTLLDQSRVIRPHPAFRLFATANTVGLGDTTGLYHGTQQINQAQMDRWSIVTTLNYLPHDKEVDIVAAKVKGFTADKG
RETVSKMVRVADLTRAAFINGDLSTVMSPRTVITWAENAYIFGDIAFAFRVTFLNKCDELERALVAEHYQRAFGVELKES
AANIVLEATA

Specific function: Catalyzes cobalt insertion in the corrin ring [H]

COG id: COG0714

COG function: function code R; MoxR-like ATPases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI24415404, Length=245, Percent_Identity=24.4897959183673, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI161076562, Length=145, Percent_Identity=27.5862068965517, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI161076560, Length=145, Percent_Identity=27.5862068965517, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011704
- InterPro:   IPR006537 [H]

Pfam domain/function: PF07728 AAA_5 [H]

EC number: =6.6.1.2 [H]

Molecular weight: Translated: 36835; Mature: 36704

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIDLDISNLPDTTVSVREVFGIDTDLRVPAYSKGDAYVPDIDQDYLFDRDTTLAILAG
CCEEEEECCCCCCCCEEHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHEECCCCCEEEEEE
FAHNRRVMVSGYHGTGKSTHIEQVAARLNWPCVRVNLDSHVSRIDLVGKDAIVVKDGLQV
CCCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEHHHCCCEEEECCCCEEEEECCCEE
TEFKDGILPWAYQHNVALVFDEYDAGRPDVMFVIQRVLEASGRLTLLDQSRVIRPHPAFR
EECCCCCCCEEEECCEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEE
LFATANTVGLGDTTGLYHGTQQINQAQMDRWSIVTTLNYLPHDKEVDIVAAKVKGFTADK
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHEEEEEEECCCCCCCCEEEEEEEECCCCCCC
GRETVSKMVRVADLTRAAFINGDLSTVMSPRTVITWAENAYIFGDIAFAFRVTFLNKCDE
HHHHHHHHHHHHHHHHHEEECCCHHHHCCCCEEEEEECCEEEEEEHHHHHHHHHHHHHHH
LERALVAEHYQRAFGVELKESAANIVLEATA
HHHHHHHHHHHHHHCCEECCCCCEEEEEECC
>Mature Secondary Structure 
SKIDLDISNLPDTTVSVREVFGIDTDLRVPAYSKGDAYVPDIDQDYLFDRDTTLAILAG
CEEEEECCCCCCCCEEHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHEECCCCCEEEEEE
FAHNRRVMVSGYHGTGKSTHIEQVAARLNWPCVRVNLDSHVSRIDLVGKDAIVVKDGLQV
CCCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEHHHCCCEEEECCCCEEEEECCCEE
TEFKDGILPWAYQHNVALVFDEYDAGRPDVMFVIQRVLEASGRLTLLDQSRVIRPHPAFR
EECCCCCCCEEEECCEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEE
LFATANTVGLGDTTGLYHGTQQINQAQMDRWSIVTTLNYLPHDKEVDIVAAKVKGFTADK
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHEEEEEEECCCCCCCCEEEEEEEECCCCCCC
GRETVSKMVRVADLTRAAFINGDLSTVMSPRTVITWAENAYIFGDIAFAFRVTFLNKCDE
HHHHHHHHHHHHHHHHHEEECCCHHHHCCCCEEEEEECCEEEEEEHHHHHHHHHHHHHHH
LERALVAEHYQRAFGVELKESAANIVLEATA
HHHHHHHHHHHHHHCCEECCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1917840 [H]