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The map label for this gene is atoC [H]

Identifier: 150397738

GI number: 150397738

Start: 2639706

End: 2640065

Strand: Reverse

Name: atoC [H]

Synonym: Smed_2540

Alternate gene names: 150397738

Gene position: 2640065-2639706 (Counterclockwise)

Preceding gene: 150397739

Following gene: 150397733

Centisome position: 69.81

GC content: 62.5

Gene sequence:

>360_bases
ATGGCGAAAATCCTGATCACCGAGGATGAAGATGCCCTGCGTTCCTTCGTCGCGCGCGCGTTGCGGCTCGACGGCCATGA
AACGGTCGAAGCCGGGGACGGAGCCGATGGGCTCGCCTGCCTTCGCGATCAGCCGTTCGACCTGTTGCTGTCCGATATCC
GGATGCCGGTCATGGACGGCATCGAACTCGCTCACCAGGCCGCCGCTGCATTTCCAGCATTGAAGATCCTGTTGATGACC
GGCTACGCCGAACAGCGCGAGCGTGCCGACGACCTCTCCGCGAAGGTCGTCGACGTCATCGAGAAGCCGTTTTCACTACC
CGATATTCGCAAGGCGGTTGCTCTGGCGCTGGCGGCCTGA

Upstream 100 bases:

>100_bases
TGCGGTCGCATGAGGCGTCCGACGATATGGAGATCAAACGGAGCGTTCATGGCATCCAAGCGCCACGCCGCTCCCCGCAG
CATAAATACGGGAGGCCATG

Downstream 100 bases:

>100_bases
CGCGTTCGTAAACCGTTGATGCGGGGAAAGGCGGCTCCGGAAGACGCCGCCTCCTTCGCCTGAGGCGACAAGATGGCCCG
CAGGCGGATGAGGATGCGCG

Product: response regulator receiver protein

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 119; Mature: 118

Protein sequence:

>119_residues
MAKILITEDEDALRSFVARALRLDGHETVEAGDGADGLACLRDQPFDLLLSDIRMPVMDGIELAHQAAAAFPALKILLMT
GYAEQRERADDLSAKVVDVIEKPFSLPDIRKAVALALAA

Sequences:

>Translated_119_residues
MAKILITEDEDALRSFVARALRLDGHETVEAGDGADGLACLRDQPFDLLLSDIRMPVMDGIELAHQAAAAFPALKILLMT
GYAEQRERADDLSAKVVDVIEKPFSLPDIRKAVALALAA
>Mature_118_residues
AKILITEDEDALRSFVARALRLDGHETVEAGDGADGLACLRDQPFDLLLSDIRMPVMDGIELAHQAAAAFPALKILLMTG
YAEQRERADDLSAKVVDVIEKPFSLPDIRKAVALALAA

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=117, Percent_Identity=35.8974358974359, Blast_Score=67, Evalue=3e-13,
Organism=Escherichia coli, GI1790437, Length=115, Percent_Identity=31.304347826087, Blast_Score=60, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 12858; Mature: 12727

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKILITEDEDALRSFVARALRLDGHETVEAGDGADGLACLRDQPFDLLLSDIRMPVMDG
CCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHCCHHHHH
IELAHQAAAAFPALKILLMTGYAEQRERADDLSAKVVDVIEKPFSLPDIRKAVALALAA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
AKILITEDEDALRSFVARALRLDGHETVEAGDGADGLACLRDQPFDLLLSDIRMPVMDG
CEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHCCHHHHH
IELAHQAAAAFPALKILLMTGYAEQRERADDLSAKVVDVIEKPFSLPDIRKAVALALAA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]