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The map label for this gene is ybbO [H]

Identifier: 150397726

GI number: 150397726

Start: 2627206

End: 2628039

Strand: Direct

Name: ybbO [H]

Synonym: Smed_2528

Alternate gene names: 150397726

Gene position: 2627206-2628039 (Clockwise)

Preceding gene: 150397724

Following gene: 150397727

Centisome position: 69.47

GC content: 64.27

Gene sequence:

>834_bases
ATGCCGGATCGCCCCACGATTATCGTCACCGGTTGCTCCTCGGGTATCGGAGCCTATTGCGCGCGTGCGCTGAAGCGGGA
CGGCTGGCGCGTCTTCGCGACGGTGCGGCGGCCCGAGGATCAGCCGCCGCTCGAAGCCGAGGGCATCGAGACCTTCATCA
TGGACTATACCAGGCCGGAGACGATTGCCGCCCTGGTCGAGGCTGTGATGGCGCTGAGCGGCGGACAGATCGATGCATTG
TTCAACAATGGCGCCTATGGTCAGGCCGGCGCGGTCGAGGACCTGCCGACCGAAGCCTTGCGGCTCCAGCTCGAGACCAA
CGTGATCGGCTGGCACGACCTGACGCGGCGCGTCATCCCGGCGATGCGCGCTCGTGGACAGGGCCGCATCGTCCAGTGCT
CGTCCATTCTCGGCATCGTGCCCTACCGATGGCGCGGCGCTTATAACGCCTCGAAGTTCGCGCTCGAAGCGCTGTCGCTC
ACATTGCGAATGGAACTCGCCGGCAGCGGCATCGAGGTGAGCCTGATCGAGCCGGGGCCGATCGCATCGAAATTCACGGC
CAACGCGATCGCCTATATCGAGCGGTTCATAGATCTTGAAAATTCAGTCCATCGCGCGGAATACGCGCGGCAGATGCGGC
GCCTGCGCGGCGAAAGCAAGCCGGCACCCGGAAAACTCGGCCCGGACGCCGTCTACGCGGCGCTGAAACAAGCTTTGACG
GCACGCCGCCCGAGGCCGCATTATATCGTAACAAGGCCAGCCAGACAGGGAGCGCTCCTGAAAAAGCTCCTGCCGGCGGC
GCTATTCTATCGCATCATCGGTCGTCTCGGCTGA

Upstream 100 bases:

>100_bases
GCCTTGACCATCTCCGGTCCGGCCAACCCCCATGCAATTCAATTGTATCGCATCGATGAATATGGGAAATGGGGCTTGCA
TTGCTACAGGAATCGAGTGG

Downstream 100 bases:

>100_bases
CCGTATTACAAGGACTTACGCCATGAACAGCTTCCTGACCGGTCTGACCCTGCTCGTCATGGGCCTGGTTGCGATCGTGC
TCATCCGCGGTCTCCTCAAC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MPDRPTIIVTGCSSGIGAYCARALKRDGWRVFATVRRPEDQPPLEAEGIETFIMDYTRPETIAALVEAVMALSGGQIDAL
FNNGAYGQAGAVEDLPTEALRLQLETNVIGWHDLTRRVIPAMRARGQGRIVQCSSILGIVPYRWRGAYNASKFALEALSL
TLRMELAGSGIEVSLIEPGPIASKFTANAIAYIERFIDLENSVHRAEYARQMRRLRGESKPAPGKLGPDAVYAALKQALT
ARRPRPHYIVTRPARQGALLKKLLPAALFYRIIGRLG

Sequences:

>Translated_277_residues
MPDRPTIIVTGCSSGIGAYCARALKRDGWRVFATVRRPEDQPPLEAEGIETFIMDYTRPETIAALVEAVMALSGGQIDAL
FNNGAYGQAGAVEDLPTEALRLQLETNVIGWHDLTRRVIPAMRARGQGRIVQCSSILGIVPYRWRGAYNASKFALEALSL
TLRMELAGSGIEVSLIEPGPIASKFTANAIAYIERFIDLENSVHRAEYARQMRRLRGESKPAPGKLGPDAVYAALKQALT
ARRPRPHYIVTRPARQGALLKKLLPAALFYRIIGRLG
>Mature_276_residues
PDRPTIIVTGCSSGIGAYCARALKRDGWRVFATVRRPEDQPPLEAEGIETFIMDYTRPETIAALVEAVMALSGGQIDALF
NNGAYGQAGAVEDLPTEALRLQLETNVIGWHDLTRRVIPAMRARGQGRIVQCSSILGIVPYRWRGAYNASKFALEALSLT
LRMELAGSGIEVSLIEPGPIASKFTANAIAYIERFIDLENSVHRAEYARQMRRLRGESKPAPGKLGPDAVYAALKQALTA
RRPRPHYIVTRPARQGALLKKLLPAALFYRIIGRLG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7657478, Length=259, Percent_Identity=30.5019305019305, Blast_Score=107, Evalue=8e-24,
Organism=Homo sapiens, GI223718074, Length=266, Percent_Identity=30.0751879699248, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI40548397, Length=278, Percent_Identity=28.4172661870504, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI214010158, Length=278, Percent_Identity=28.4172661870504, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI214010156, Length=278, Percent_Identity=28.4172661870504, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI22758144, Length=278, Percent_Identity=28.4172661870504, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI19743808, Length=292, Percent_Identity=29.7945205479452, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI150247226, Length=253, Percent_Identity=29.2490118577075, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI7706318, Length=196, Percent_Identity=35.7142857142857, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI119392083, Length=257, Percent_Identity=29.9610894941634, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI20149619, Length=195, Percent_Identity=29.7435897435897, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI50726952, Length=281, Percent_Identity=29.1814946619217, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI32483357, Length=186, Percent_Identity=34.4086021505376, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI22507405, Length=178, Percent_Identity=33.7078651685393, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI44680136, Length=260, Percent_Identity=26.9230769230769, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI44680133, Length=260, Percent_Identity=26.9230769230769, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI17738292, Length=260, Percent_Identity=26.9230769230769, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI5031737, Length=235, Percent_Identity=28.936170212766, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI126723191, Length=177, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786701, Length=270, Percent_Identity=36.6666666666667, Blast_Score=175, Evalue=4e-45,
Organism=Escherichia coli, GI87082100, Length=216, Percent_Identity=30.5555555555556, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787820, Length=190, Percent_Identity=30.5263157894737, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787335, Length=183, Percent_Identity=28.9617486338798, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1786812, Length=176, Percent_Identity=29.5454545454545, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115534660, Length=292, Percent_Identity=26.027397260274, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI193210355, Length=262, Percent_Identity=25.9541984732824, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17570069, Length=206, Percent_Identity=27.1844660194175, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71997402, Length=207, Percent_Identity=27.0531400966184, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=191, Percent_Identity=27.7486910994764, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=195, Percent_Identity=30.2564102564103, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322067, Length=171, Percent_Identity=28.0701754385965, Blast_Score=69, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21358495, Length=198, Percent_Identity=29.7979797979798, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI23397609, Length=189, Percent_Identity=31.2169312169312, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI28571526, Length=187, Percent_Identity=31.5508021390374, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21357041, Length=187, Percent_Identity=32.0855614973262, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24651139, Length=272, Percent_Identity=26.1029411764706, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI28571387, Length=194, Percent_Identity=30.4123711340206, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI21355319, Length=186, Percent_Identity=28.494623655914, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 30410; Mature: 30278

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDRPTIIVTGCSSGIGAYCARALKRDGWRVFATVRRPEDQPPLEAEGIETFIMDYTRPE
CCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHCCCCHH
TIAALVEAVMALSGGQIDALFNNGAYGQAGAVEDLPTEALRLQLETNVIGWHDLTRRVIP
HHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHEEEEECCEECHHHHHHHHHH
AMRARGQGRIVQCSSILGIVPYRWRGAYNASKFALEALSLTLRMELAGSGIEVSLIEPGP
HHHCCCCCCEEEECHHHHCCCCCCCCCCCHHHHHHHHHHHHHEEEECCCCEEEEEECCCC
IASKFTANAIAYIERFIDLENSVHRAEYARQMRRLRGESKPAPGKLGPDAVYAALKQALT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
ARRPRPHYIVTRPARQGALLKKLLPAALFYRIIGRLG
HCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PDRPTIIVTGCSSGIGAYCARALKRDGWRVFATVRRPEDQPPLEAEGIETFIMDYTRPE
CCCCEEEEEECCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHCCCCHH
TIAALVEAVMALSGGQIDALFNNGAYGQAGAVEDLPTEALRLQLETNVIGWHDLTRRVIP
HHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHEEEEECCEECHHHHHHHHHH
AMRARGQGRIVQCSSILGIVPYRWRGAYNASKFALEALSLTLRMELAGSGIEVSLIEPGP
HHHCCCCCCEEEECHHHHCCCCCCCCCCCHHHHHHHHHHHHHEEEECCCCEEEEEECCCC
IASKFTANAIAYIERFIDLENSVHRAEYARQMRRLRGESKPAPGKLGPDAVYAALKQALT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
ARRPRPHYIVTRPARQGALLKKLLPAALFYRIIGRLG
HCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]