Click here to switch to the map view.

The map label for this gene is ubiG [H]

Identifier: 150397704

GI number: 150397704

Start: 2604673

End: 2605419

Strand: Direct

Name: ubiG [H]

Synonym: Smed_2506

Alternate gene names: 150397704

Gene position: 2604673-2605419 (Clockwise)

Preceding gene: 150397703

Following gene: 150397709

Centisome position: 68.87

GC content: 61.85

Gene sequence:

>747_bases
ATGAGCGAAACGGCGCGCACCACGATCGACCAGAGCGAGGTGGACCGCTTTTCGGCCATGGCGGCCGAATGGTGGGATCC
GACGGGTAAATTCCGCCCGCTGCACAAATTCAATCCGGTGCGTCTCGCCTACATTCGCGACAGGGTGGCGGAGCATTTCG
GCCGCGATCCGAAGAGCCGGCAGCCGCTTGAAGGACTGAGGCTCCTCGATATCGGCTGCGGCGGCGGCCTCCTTTGCGAG
CCGATGGCCCGCATGGGCGCGGACGTGCTCGGAGCCGACGCCTCCGAAAAGAACATCGGTATTGCCAGGACACATGCGGC
CGGCAGCGGCGTCCGCGTCGACTACCGTGCCGTGACTGCAGAGGCTCTTGCCGAAGCCGGCGAAAGTTTCGACGTCGTTC
TCAATATGGAAGTGGTCGAGCATGTCGCAGACGTGGATTTTTTCATGACGACCTGTGCGCATATGGTGCGGCCCGGCGGG
ATGATGTTCGTGGCCACCATCAACCGCACGCTGAAGGCGGCGGCACTGGCGATCTTCGCCGCGGAGAACGTGCTGCGCTG
GTTGCCGCGCGGCACCCACCAATATGAAAAGCTGGTACGCCCGGAGGAGATCGAAAACCCACTCGTCGCAAGCGGCCTGG
AAATTGCAGACCGCACCGGCGTCTTCTTCAATCCGCTTTCCAACCAGTGGAACCTGTCCAAGGATATGGACGTCAACTAT
ATGATCGTTGCGAAGCGGCCGATCTGA

Upstream 100 bases:

>100_bases
GCCCTTGACATCCCACTTCGATCGTCCGACTTCACCATGGGAATGAAGACGCAGCGAGCGGACTCCTCATGAATCCGCCC
GGACAAGCAAGGAGGCTCTG

Downstream 100 bases:

>100_bases
ACTCTGCAATCGTCAGTTCGCGTCGTCGGGCAATACCGGCAGCGGCGCGATCTCTATGCCCTCTTCGATAAGAGCGATCG
CCTCTTCTGCGGTGGCCTTG

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase [H]

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MSETARTTIDQSEVDRFSAMAAEWWDPTGKFRPLHKFNPVRLAYIRDRVAEHFGRDPKSRQPLEGLRLLDIGCGGGLLCE
PMARMGADVLGADASEKNIGIARTHAAGSGVRVDYRAVTAEALAEAGESFDVVLNMEVVEHVADVDFFMTTCAHMVRPGG
MMFVATINRTLKAAALAIFAAENVLRWLPRGTHQYEKLVRPEEIENPLVASGLEIADRTGVFFNPLSNQWNLSKDMDVNY
MIVAKRPI

Sequences:

>Translated_248_residues
MSETARTTIDQSEVDRFSAMAAEWWDPTGKFRPLHKFNPVRLAYIRDRVAEHFGRDPKSRQPLEGLRLLDIGCGGGLLCE
PMARMGADVLGADASEKNIGIARTHAAGSGVRVDYRAVTAEALAEAGESFDVVLNMEVVEHVADVDFFMTTCAHMVRPGG
MMFVATINRTLKAAALAIFAAENVLRWLPRGTHQYEKLVRPEEIENPLVASGLEIADRTGVFFNPLSNQWNLSKDMDVNY
MIVAKRPI
>Mature_247_residues
SETARTTIDQSEVDRFSAMAAEWWDPTGKFRPLHKFNPVRLAYIRDRVAEHFGRDPKSRQPLEGLRLLDIGCGGGLLCEP
MARMGADVLGADASEKNIGIARTHAAGSGVRVDYRAVTAEALAEAGESFDVVLNMEVVEHVADVDFFMTTCAHMVRPGGM
MFVATINRTLKAAALAIFAAENVLRWLPRGTHQYEKLVRPEEIENPLVASGLEIADRTGVFFNPLSNQWNLSKDMDVNYM
IVAKRPI

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family [H]

Homologues:

Organism=Homo sapiens, GI118600965, Length=250, Percent_Identity=39.2, Blast_Score=213, Evalue=2e-55,
Organism=Escherichia coli, GI1788564, Length=237, Percent_Identity=40.5063291139241, Blast_Score=195, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI115533050, Length=248, Percent_Identity=35.0806451612903, Blast_Score=157, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6324476, Length=281, Percent_Identity=28.4697508896797, Blast_Score=108, Evalue=7e-25,
Organism=Drosophila melanogaster, GI281365311, Length=244, Percent_Identity=31.9672131147541, Blast_Score=137, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24585589, Length=209, Percent_Identity=34.9282296650718, Blast_Score=132, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR010233 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.64 [H]

Molecular weight: Translated: 27462; Mature: 27331

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETARTTIDQSEVDRFSAMAAEWWDPTGKFRPLHKFNPVRLAYIRDRVAEHFGRDPKSR
CCCCHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
QPLEGLRLLDIGCGGGLLCEPMARMGADVLGADASEKNIGIARTHAAGSGVRVDYRAVTA
CCCCCCEEEEECCCCCHHHHHHHHCCCHHCCCCCCCCCCCEEEECCCCCCCEEEHHHHHH
EALAEAGESFDVVLNMEVVEHVADVDFFMTTCAHMVRPGGMMFVATINRTLKAAALAIFA
HHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHH
AENVLRWLPRGTHQYEKLVRPEEIENPLVASGLEIADRTGVFFNPLSNQWNLSKDMDVNY
HHHHHHHCCCCHHHHHHCCCCHHHCCCHHHCCCCHHCCCCEEECCCCCCCCCCCCCCCCE
MIVAKRPI
EEEECCCC
>Mature Secondary Structure 
SETARTTIDQSEVDRFSAMAAEWWDPTGKFRPLHKFNPVRLAYIRDRVAEHFGRDPKSR
CCCHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
QPLEGLRLLDIGCGGGLLCEPMARMGADVLGADASEKNIGIARTHAAGSGVRVDYRAVTA
CCCCCCEEEEECCCCCHHHHHHHHCCCHHCCCCCCCCCCCEEEECCCCCCCEEEHHHHHH
EALAEAGESFDVVLNMEVVEHVADVDFFMTTCAHMVRPGGMMFVATINRTLKAAALAIFA
HHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHH
AENVLRWLPRGTHQYEKLVRPEEIENPLVASGLEIADRTGVFFNPLSNQWNLSKDMDVNY
HHHHHHHCCCCHHHHHHCCCCHHHCCCHHHCCCCHHCCCCEEECCCCCCCCCCCCCCCCE
MIVAKRPI
EEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]