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The map label for this gene is tkt1 [H]

Identifier: 150397679

GI number: 150397679

Start: 2561742

End: 2563736

Strand: Reverse

Name: tkt1 [H]

Synonym: Smed_2479

Alternate gene names: 150397679

Gene position: 2563736-2561742 (Counterclockwise)

Preceding gene: 150397680

Following gene: 150397678

Centisome position: 67.79

GC content: 62.41

Gene sequence:

>1995_bases
ATGTTCCACCGCCGTGAACTGGCGAACGCAATTCGTTTCCTGACTGTCGACGTCGTGCAGAAGGCCAATTCCGGCCATCC
CGGGACCGCAATGGGCATGGCGGATATTGCCGAGGTGCTTTGGAACGATTTTCTCAGGCACAATCCGGTCAATCCGAGAT
GGATCAACCGTGACCGTTTCGTTCAGTCGAACGGGCATGGTTCGATGCTGACCTATTCGCTGCTGCATCTCTCCGGCTAC
GGGGTGACGATTCAGGATTTGAAAGATCATCGAAAGCTGCATTCGAAGACGCCGGGCCATCCGGAATACGGCGTGACGGC
CGGAGTCGAGACGACCACCGGTCCGCTTGGCCAGGGCTTCGCCACGGCGGTCGGAATGGCTCTGGCGGAAAAGAAGCTGG
CGCAGGAGTTCAACCGCGCCGGTTTCCCCATAGTCGATCACTTCACTTACGTTTTCGTTGGGGACGGCTGCCTCATGGAG
GGGGTCGCGCAGGAGGCAGCCTCGCTTGCCGGTACTTTGAAGCTCAACAAGCTGGTCGCTGTCTATGACGACAACAAGAT
CTCCATCGACGGCGAGACGCCCGGCTGGTTCGCCGACGATAGCGCCGCTCGTTTCCGTGCGCTCGGCTGGAACGTCATTG
CGGATGTGGACGGCCATGATGCCGGCGCCATCGCCGCGGCATTTGCCGCTGCCCGCCAGTCGCAGGACAGGCCGACCATG
ATCTGCTGCAAGACGGTGATCGGTTATGGCTCGCCGAACAAGCAGGGCAAGGAAGAGGTGCATGGCGCACCGCTCGGCGT
GGAAGAAGTGGCGCGCACCCGCGAGCACCTCGGCTGGGCTCATGAGGCTTTCATCGTGCCGGACGCCGTGATGCAGGCCT
GGGATGCCCGTCCGCGCGGCGAAAAAGCGGAAGCCGAATGGAGGACCCTTTTCGAGCGTTACAGAACAAAGCATCCGGAT
CTTGCGGCCGAACTGGAACGCCGTAGCGCCGGGCGGCTTCCGGACGGTTTCGACGCGGCCTTTGCGCGCGAGGCCGATCG
CATTCTTGGCGGCGAGCCGATCAGGCAGCCGATCCGCAAGGCTTCGAACCGCGTCCTCGGCAATTTGCTTGAAGGCCTCC
CGGAAGTGATCGGTGGTTCCGCCGATGTTTCCGTGTCGACGCTGGCATGGACCAGTGCAGCCCGCTCCATCACGCCGGAC
GATTTTTCAGGGAATTTCGTGCATTACGGCGTGCGGGAGTTCGGCATGTCCGCCATGATGAACGGTATGGCCGCCCATGG
CGGTCTCATTCCCTACGGTGCCTGTTATCTCGTCTTCAGCGACTATAGCCGCAATGCCGTGCGCCTTTCGGCCCTGATGG
GTCTCAAGGCGATCTTTCTCTACACGCATGATTCGGTCGGTGTCGGCGAGGACGGACCGACGCACCAGCCCTGCGAGCAG
CTCGTGGCGCTCCGCGCTGTTCCCAACATGTCGCTGTGGCGGCCGGGCAGCGAGCTGGAAGCGCTTGTTGCCTGGGAATC
CGCTTTGAAGCGCGAGGGGCCTAGCGTGATCGTCGCCGCGCGCCAGGAAGGTGGGGTGTTTGCGCACGAAAGCAGCGACA
TCGACGGCATCCGCCGCGGCGGGTACGTGCTGAAGGATTCCGGCGCCAAACCGGACATCGTCCTTGCTGCGACCGGATCG
GAGATCGGCCTCATCCTCGAAGCGGCGGCAGTACTGGAGGAGCAAGGCAAAGCGGTGCGGCTGGCTTCCATTCCCAACGG
CAATCTCTTCGCACGGCAGGACCGCGGCTATCAGGAAAGCGTCCTGGCTTTCGGCACGCCGACGGTTTTCGTGGAGGCTG
CATCGCCGCTTTATTGGTACCAGTTCCTCAAGGGACCGGGTACGGTGGTCGGTGTGGATCGTTTCGGCGAATCAGCGCCC
GGACCGGAGATCTATCGCGTCATGAACCTGACGGCCGAGCGGATCGTGTCCGAGGCCAGTCAACTCTTGCGCTGA

Upstream 100 bases:

>100_bases
GAGCGACCGGCATAGACGACTTCTCGTGTCTTCAGAAATCGTTCTTGTCATGTTGTAATGACAACATTATAGGGTGAAGA
GAGAATCTGGAGGCTTGTAC

Downstream 100 bases:

>100_bases
CGCGATGACTGCCAGACGACGGGGGAAGCATGTATCTCGGTATCGACCTTGGCACCGGTTCGGTCAAAGCACTTCTGATC
GACGATGACGGAAGGGCTGT

Product: transketolase

Products: NA

Alternate protein names: TK 1 [H]

Number of amino acids: Translated: 664; Mature: 664

Protein sequence:

>664_residues
MFHRRELANAIRFLTVDVVQKANSGHPGTAMGMADIAEVLWNDFLRHNPVNPRWINRDRFVQSNGHGSMLTYSLLHLSGY
GVTIQDLKDHRKLHSKTPGHPEYGVTAGVETTTGPLGQGFATAVGMALAEKKLAQEFNRAGFPIVDHFTYVFVGDGCLME
GVAQEAASLAGTLKLNKLVAVYDDNKISIDGETPGWFADDSAARFRALGWNVIADVDGHDAGAIAAAFAAARQSQDRPTM
ICCKTVIGYGSPNKQGKEEVHGAPLGVEEVARTREHLGWAHEAFIVPDAVMQAWDARPRGEKAEAEWRTLFERYRTKHPD
LAAELERRSAGRLPDGFDAAFAREADRILGGEPIRQPIRKASNRVLGNLLEGLPEVIGGSADVSVSTLAWTSAARSITPD
DFSGNFVHYGVREFGMSAMMNGMAAHGGLIPYGACYLVFSDYSRNAVRLSALMGLKAIFLYTHDSVGVGEDGPTHQPCEQ
LVALRAVPNMSLWRPGSELEALVAWESALKREGPSVIVAARQEGGVFAHESSDIDGIRRGGYVLKDSGAKPDIVLAATGS
EIGLILEAAAVLEEQGKAVRLASIPNGNLFARQDRGYQESVLAFGTPTVFVEAASPLYWYQFLKGPGTVVGVDRFGESAP
GPEIYRVMNLTAERIVSEASQLLR

Sequences:

>Translated_664_residues
MFHRRELANAIRFLTVDVVQKANSGHPGTAMGMADIAEVLWNDFLRHNPVNPRWINRDRFVQSNGHGSMLTYSLLHLSGY
GVTIQDLKDHRKLHSKTPGHPEYGVTAGVETTTGPLGQGFATAVGMALAEKKLAQEFNRAGFPIVDHFTYVFVGDGCLME
GVAQEAASLAGTLKLNKLVAVYDDNKISIDGETPGWFADDSAARFRALGWNVIADVDGHDAGAIAAAFAAARQSQDRPTM
ICCKTVIGYGSPNKQGKEEVHGAPLGVEEVARTREHLGWAHEAFIVPDAVMQAWDARPRGEKAEAEWRTLFERYRTKHPD
LAAELERRSAGRLPDGFDAAFAREADRILGGEPIRQPIRKASNRVLGNLLEGLPEVIGGSADVSVSTLAWTSAARSITPD
DFSGNFVHYGVREFGMSAMMNGMAAHGGLIPYGACYLVFSDYSRNAVRLSALMGLKAIFLYTHDSVGVGEDGPTHQPCEQ
LVALRAVPNMSLWRPGSELEALVAWESALKREGPSVIVAARQEGGVFAHESSDIDGIRRGGYVLKDSGAKPDIVLAATGS
EIGLILEAAAVLEEQGKAVRLASIPNGNLFARQDRGYQESVLAFGTPTVFVEAASPLYWYQFLKGPGTVVGVDRFGESAP
GPEIYRVMNLTAERIVSEASQLLR
>Mature_664_residues
MFHRRELANAIRFLTVDVVQKANSGHPGTAMGMADIAEVLWNDFLRHNPVNPRWINRDRFVQSNGHGSMLTYSLLHLSGY
GVTIQDLKDHRKLHSKTPGHPEYGVTAGVETTTGPLGQGFATAVGMALAEKKLAQEFNRAGFPIVDHFTYVFVGDGCLME
GVAQEAASLAGTLKLNKLVAVYDDNKISIDGETPGWFADDSAARFRALGWNVIADVDGHDAGAIAAAFAAARQSQDRPTM
ICCKTVIGYGSPNKQGKEEVHGAPLGVEEVARTREHLGWAHEAFIVPDAVMQAWDARPRGEKAEAEWRTLFERYRTKHPD
LAAELERRSAGRLPDGFDAAFAREADRILGGEPIRQPIRKASNRVLGNLLEGLPEVIGGSADVSVSTLAWTSAARSITPD
DFSGNFVHYGVREFGMSAMMNGMAAHGGLIPYGACYLVFSDYSRNAVRLSALMGLKAIFLYTHDSVGVGEDGPTHQPCEQ
LVALRAVPNMSLWRPGSELEALVAWESALKREGPSVIVAARQEGGVFAHESSDIDGIRRGGYVLKDSGAKPDIVLAATGS
EIGLILEAAAVLEEQGKAVRLASIPNGNLFARQDRGYQESVLAFGTPTVFVEAASPLYWYQFLKGPGTVVGVDRFGESAP
GPEIYRVMNLTAERIVSEASQLLR

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=583, Percent_Identity=25.7289879931389, Blast_Score=160, Evalue=4e-39,
Organism=Homo sapiens, GI4507521, Length=583, Percent_Identity=25.7289879931389, Blast_Score=160, Evalue=4e-39,
Organism=Homo sapiens, GI133778974, Length=581, Percent_Identity=25.473321858864, Blast_Score=140, Evalue=5e-33,
Organism=Homo sapiens, GI225637459, Length=524, Percent_Identity=21.7557251908397, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI225637461, Length=420, Percent_Identity=23.3333333333333, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI225637463, Length=420, Percent_Identity=23.3333333333333, Blast_Score=97, Evalue=5e-20,
Organism=Escherichia coli, GI1788808, Length=662, Percent_Identity=53.4743202416918, Blast_Score=733, Evalue=0.0,
Organism=Escherichia coli, GI48994911, Length=665, Percent_Identity=52.3308270676692, Blast_Score=724, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539652, Length=572, Percent_Identity=26.048951048951, Blast_Score=154, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6325331, Length=667, Percent_Identity=44.527736131934, Blast_Score=540, Evalue=1e-154,
Organism=Saccharomyces cerevisiae, GI6319593, Length=670, Percent_Identity=42.5373134328358, Blast_Score=515, Evalue=1e-147,
Organism=Drosophila melanogaster, GI45551847, Length=579, Percent_Identity=26.0794473229706, Blast_Score=162, Evalue=6e-40,
Organism=Drosophila melanogaster, GI45550715, Length=579, Percent_Identity=26.0794473229706, Blast_Score=162, Evalue=6e-40,
Organism=Drosophila melanogaster, GI24645119, Length=545, Percent_Identity=25.8715596330275, Blast_Score=139, Evalue=6e-33,
Organism=Drosophila melanogaster, GI24666278, Length=262, Percent_Identity=32.824427480916, Blast_Score=129, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 71837; Mature: 71837

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS00801 TRANSKETOLASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFHRRELANAIRFLTVDVVQKANSGHPGTAMGMADIAEVLWNDFLRHNPVNPRWINRDRF
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEECCCCE
VQSNGHGSMLTYSLLHLSGYGVTIQDLKDHRKLHSKTPGHPEYGVTAGVETTTGPLGQGF
EECCCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHH
ATAVGMALAEKKLAQEFNRAGFPIVDHFTYVFVGDGCLMEGVAQEAASLAGTLKLNKLVA
HHHHHHHHHHHHHHHHHHHCCCCHHHCEEEEEECCCHHHHHHHHHHHHHHHHEEEEEEEE
VYDDNKISIDGETPGWFADDSAARFRALGWNVIADVDGHDAGAIAAAFAAARQSQDRPTM
EEECCEEEECCCCCCCCCCCCHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCHH
ICCKTVIGYGSPNKQGKEEVHGAPLGVEEVARTREHLGWAHEAFIVPDAVMQAWDARPRG
HHHHHHHCCCCCCCCCHHHHCCCCCCHHHHHHHHHHCCCHHHEEECCHHHHHHHCCCCCC
EKAEAEWRTLFERYRTKHPDLAAELERRSAGRLPDGFDAAFAREADRILGGEPIRQPIRK
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHH
ASNRVLGNLLEGLPEVIGGSADVSVSTLAWTSAARSITPDDFSGNFVHYGVREFGMSAMM
HHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHCCCCCCCCCCCEEEECHHHHHHHHHH
NGMAAHGGLIPYGACYLVFSDYSRNAVRLSALMGLKAIFLYTHDSVGVGEDGPTHQPCEQ
HHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHCCEEEEEEECCCCCCCCCCCCHHHHHH
LVALRAVPNMSLWRPGSELEALVAWESALKREGPSVIVAARQEGGVFAHESSDIDGIRRG
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEECCCCCCHHHHC
GYVLKDSGAKPDIVLAATGSEIGLILEAAAVLEEQGKAVRLASIPNGNLFARQDRGYQES
CEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCEEEEEECCCCCEEEECCCCCHHH
VLAFGTPTVFVEAASPLYWYQFLKGPGTVVGVDRFGESAPGPEIYRVMNLTAERIVSEAS
HHCCCCCEEEEECCCCHHHHHHHCCCCCEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
QLLR
HHCC
>Mature Secondary Structure
MFHRRELANAIRFLTVDVVQKANSGHPGTAMGMADIAEVLWNDFLRHNPVNPRWINRDRF
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEECCCCE
VQSNGHGSMLTYSLLHLSGYGVTIQDLKDHRKLHSKTPGHPEYGVTAGVETTTGPLGQGF
EECCCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHH
ATAVGMALAEKKLAQEFNRAGFPIVDHFTYVFVGDGCLMEGVAQEAASLAGTLKLNKLVA
HHHHHHHHHHHHHHHHHHHCCCCHHHCEEEEEECCCHHHHHHHHHHHHHHHHEEEEEEEE
VYDDNKISIDGETPGWFADDSAARFRALGWNVIADVDGHDAGAIAAAFAAARQSQDRPTM
EEECCEEEECCCCCCCCCCCCHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCHH
ICCKTVIGYGSPNKQGKEEVHGAPLGVEEVARTREHLGWAHEAFIVPDAVMQAWDARPRG
HHHHHHHCCCCCCCCCHHHHCCCCCCHHHHHHHHHHCCCHHHEEECCHHHHHHHCCCCCC
EKAEAEWRTLFERYRTKHPDLAAELERRSAGRLPDGFDAAFAREADRILGGEPIRQPIRK
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHH
ASNRVLGNLLEGLPEVIGGSADVSVSTLAWTSAARSITPDDFSGNFVHYGVREFGMSAMM
HHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHCCCCCCCCCCCEEEECHHHHHHHHHH
NGMAAHGGLIPYGACYLVFSDYSRNAVRLSALMGLKAIFLYTHDSVGVGEDGPTHQPCEQ
HHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHCCEEEEEEECCCCCCCCCCCCHHHHHH
LVALRAVPNMSLWRPGSELEALVAWESALKREGPSVIVAARQEGGVFAHESSDIDGIRRG
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEECCCCCCHHHHC
GYVLKDSGAKPDIVLAATGSEIGLILEAAAVLEEQGKAVRLASIPNGNLFARQDRGYQES
CEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCEEEEEECCCCCEEEECCCCCHHH
VLAFGTPTVFVEAASPLYWYQFLKGPGTVVGVDRFGESAPGPEIYRVMNLTAERIVSEAS
HHCCCCCEEEEECCCCHHHHHHHCCCCCEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
QLLR
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA