| Definition | Sinorhizobium medicae WSM419 chromosome, complete genome. |
|---|---|
| Accession | NC_009636 |
| Length | 3,781,904 |
Click here to switch to the map view.
The map label for this gene is gno [H]
Identifier: 150397672
GI number: 150397672
Start: 2553948
End: 2554706
Strand: Direct
Name: gno [H]
Synonym: Smed_2472
Alternate gene names: 150397672
Gene position: 2553948-2554706 (Clockwise)
Preceding gene: 150397671
Following gene: 150397677
Centisome position: 67.53
GC content: 63.77
Gene sequence:
>759_bases ATGAAAGAGATCATCGATACGTTTCGTCCAGACCTGTTTGCCGGCAGGGATATTCTGATTACCGGCGGTTCGTCCGGCAT CGGCCTTGCCATCGCGCAGGGTTTTGCCCGGCTCGGCGGCACGGTCATCGCGCTGGGCAGCTCTGAATCCAAGCTCAAGG CCGCCGCGGCCGATCCGGAAAACAAGGGCATCCGCTTCGAGCGCGTCGACGTGCGCGATCCGGAAATGATCAACGCATTC GCCAAGACTCTCGGCAAGCTCGACGTTCTCATCAACGGCGCAGGCATCGCCCGGCCCGAGGCGGAATTCGAGGACGCGAC CTACATGGAGGTGATGGACGTCAACCTGAACAGCCAGATGCGCTTCGCCATGGCCGTCCTGCCGCTCCTGAAAGCCTCGC GCGGCGTCATCCTCAACACCGCCTCCATGCTGAGCTATGTCAGCGATCCGCTCGTGCCGGCCTATGGCGCCAGCAAATCG GGCGTGCTCGGCCTCACTCGCCATCTCGCCCACGCCTTCGGCCCGGATGGCATCCGCGTCAACGCCATCTCTCCCGGCTA TCACAAGACGGACATGACCAGGGGTCTGTGGACCGACCCGGTGCCGGCCGAGAAAATCGCCCAGCGTTCAGCGCTCAAGC GCTGGGGTACGGTGGATGACCTTGTTGGAACCGCGCTCTTCCTGGCCTCGCCGGCCGCGGAATTCATTACCGGCGCCGAC CTGCCGGTCGATGGCGGTTTCGTGGTCGGCAGCTTCTGA
Upstream 100 bases:
>100_bases CAGCACGGCGCTCTATGACGACATGGATGCGCTTTCCGCCCGGATTCGCCAAGCCAGCGCCGGGACCTGAACCACGACGA TCATGCCTGAGGAGGAATTC
Downstream 100 bases:
>100_bases GACATCGGCTTTCGCGGAATGCGGGCGGAAACCCTACACGGCTTTCTGCCCGCATTCCGCTTTGACTTAGATTGTTAGGT CGATCCGAACTAACGCATTG
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 5-keto-D-gluconate 5-reductase [H]
Number of amino acids: Translated: 252; Mature: 252
Protein sequence:
>252_residues MKEIIDTFRPDLFAGRDILITGGSSGIGLAIAQGFARLGGTVIALGSSESKLKAAAADPENKGIRFERVDVRDPEMINAF AKTLGKLDVLINGAGIARPEAEFEDATYMEVMDVNLNSQMRFAMAVLPLLKASRGVILNTASMLSYVSDPLVPAYGASKS GVLGLTRHLAHAFGPDGIRVNAISPGYHKTDMTRGLWTDPVPAEKIAQRSALKRWGTVDDLVGTALFLASPAAEFITGAD LPVDGGFVVGSF
Sequences:
>Translated_252_residues MKEIIDTFRPDLFAGRDILITGGSSGIGLAIAQGFARLGGTVIALGSSESKLKAAAADPENKGIRFERVDVRDPEMINAF AKTLGKLDVLINGAGIARPEAEFEDATYMEVMDVNLNSQMRFAMAVLPLLKASRGVILNTASMLSYVSDPLVPAYGASKS GVLGLTRHLAHAFGPDGIRVNAISPGYHKTDMTRGLWTDPVPAEKIAQRSALKRWGTVDDLVGTALFLASPAAEFITGAD LPVDGGFVVGSF >Mature_252_residues MKEIIDTFRPDLFAGRDILITGGSSGIGLAIAQGFARLGGTVIALGSSESKLKAAAADPENKGIRFERVDVRDPEMINAF AKTLGKLDVLINGAGIARPEAEFEDATYMEVMDVNLNSQMRFAMAVLPLLKASRGVILNTASMLSYVSDPLVPAYGASKS GVLGLTRHLAHAFGPDGIRVNAISPGYHKTDMTRGLWTDPVPAEKIAQRSALKRWGTVDDLVGTALFLASPAAEFITGAD LPVDGGFVVGSF
Specific function: Involved in the non-phosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate. Dependent on NADP, almost inactive with NAD [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI7705925, Length=243, Percent_Identity=32.5102880658436, Blast_Score=107, Evalue=8e-24, Organism=Homo sapiens, GI19923817, Length=254, Percent_Identity=31.496062992126, Blast_Score=104, Evalue=9e-23, Organism=Homo sapiens, GI32483357, Length=248, Percent_Identity=29.8387096774194, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI5031737, Length=248, Percent_Identity=29.0322580645161, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI10190704, Length=252, Percent_Identity=34.1269841269841, Blast_Score=101, Evalue=6e-22, Organism=Homo sapiens, GI40254992, Length=235, Percent_Identity=31.4893617021277, Blast_Score=93, Evalue=2e-19, Organism=Homo sapiens, GI66933014, Length=241, Percent_Identity=31.5352697095436, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI126723750, Length=251, Percent_Identity=27.8884462151394, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI33667109, Length=197, Percent_Identity=29.9492385786802, Blast_Score=81, Evalue=7e-16, Organism=Homo sapiens, GI59889578, Length=233, Percent_Identity=28.3261802575107, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI15277342, Length=248, Percent_Identity=27.8225806451613, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI4758504, Length=199, Percent_Identity=33.6683417085427, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI119392083, Length=200, Percent_Identity=31.5, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI4503301, Length=252, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI32455239, Length=163, Percent_Identity=31.2883435582822, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI5031765, Length=163, Percent_Identity=31.2883435582822, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI31542939, Length=214, Percent_Identity=27.5700934579439, Blast_Score=68, Evalue=9e-12, Organism=Homo sapiens, GI150247226, Length=190, Percent_Identity=31.0526315789474, Blast_Score=65, Evalue=4e-11, Organism=Homo sapiens, GI44680136, Length=193, Percent_Identity=27.4611398963731, Blast_Score=65, Evalue=7e-11, Organism=Homo sapiens, GI44680133, Length=193, Percent_Identity=27.4611398963731, Blast_Score=65, Evalue=7e-11, Organism=Homo sapiens, GI17738292, Length=193, Percent_Identity=27.4611398963731, Blast_Score=65, Evalue=7e-11, Organism=Escherichia coli, GI87082160, Length=262, Percent_Identity=30.9160305343511, Blast_Score=132, Evalue=3e-32, Organism=Escherichia coli, GI1790717, Length=250, Percent_Identity=34.4, Blast_Score=132, Evalue=3e-32, Organism=Escherichia coli, GI1789208, Length=242, Percent_Identity=33.4710743801653, Blast_Score=128, Evalue=3e-31, Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=33.6065573770492, Blast_Score=116, Evalue=1e-27, Organism=Escherichia coli, GI87082100, Length=250, Percent_Identity=31.6, Blast_Score=103, Evalue=1e-23, Organism=Escherichia coli, GI1787905, Length=256, Percent_Identity=32.8125, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1786812, Length=254, Percent_Identity=27.9527559055118, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI1789378, Length=253, Percent_Identity=27.6679841897233, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI2367365, Length=247, Percent_Identity=30.3643724696356, Blast_Score=78, Evalue=5e-16, Organism=Escherichia coli, GI1788459, Length=249, Percent_Identity=30.9236947791165, Blast_Score=75, Evalue=6e-15, Organism=Escherichia coli, GI1787526, Length=197, Percent_Identity=30.9644670050761, Blast_Score=72, Evalue=5e-14, Organism=Escherichia coli, GI1787545, Length=260, Percent_Identity=28.0769230769231, Blast_Score=62, Evalue=3e-11, Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=27.7551020408163, Blast_Score=62, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17561402, Length=250, Percent_Identity=32.4, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=32.9268292682927, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI71994604, Length=245, Percent_Identity=33.469387755102, Blast_Score=109, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17555706, Length=248, Percent_Identity=32.258064516129, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI71994600, Length=244, Percent_Identity=34.0163934426229, Blast_Score=107, Evalue=5e-24, Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=30.5220883534137, Blast_Score=98, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17560676, Length=248, Percent_Identity=26.6129032258064, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17560220, Length=261, Percent_Identity=29.8850574712644, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17559104, Length=258, Percent_Identity=29.8449612403101, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI17551412, Length=197, Percent_Identity=31.9796954314721, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17562904, Length=258, Percent_Identity=29.4573643410853, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17544670, Length=271, Percent_Identity=27.6752767527675, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=27.9693486590038, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=28.1368821292776, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI72000259, Length=259, Percent_Identity=26.6409266409266, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17560332, Length=262, Percent_Identity=28.6259541984733, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=26.0536398467433, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17531453, Length=258, Percent_Identity=26.7441860465116, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17538182, Length=198, Percent_Identity=32.8282828282828, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17538480, Length=264, Percent_Identity=27.6515151515151, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17560150, Length=264, Percent_Identity=25.7575757575758, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17562908, Length=190, Percent_Identity=28.9473684210526, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17536025, Length=257, Percent_Identity=27.6264591439689, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17507613, Length=266, Percent_Identity=27.8195488721804, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI32563809, Length=266, Percent_Identity=27.8195488721804, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI17538486, Length=275, Percent_Identity=26.9090909090909, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI193204405, Length=213, Percent_Identity=28.6384976525822, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17565030, Length=253, Percent_Identity=28.0632411067194, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17562906, Length=190, Percent_Identity=26.8421052631579, Blast_Score=66, Evalue=1e-11, Organism=Caenorhabditis elegans, GI193203117, Length=197, Percent_Identity=28.9340101522843, Blast_Score=66, Evalue=1e-11, Organism=Caenorhabditis elegans, GI193203115, Length=196, Percent_Identity=29.0816326530612, Blast_Score=66, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=254, Percent_Identity=32.6771653543307, Blast_Score=111, Evalue=9e-26, Organism=Saccharomyces cerevisiae, GI6322861, Length=189, Percent_Identity=31.7460317460317, Blast_Score=69, Evalue=6e-13, Organism=Saccharomyces cerevisiae, GI6322067, Length=177, Percent_Identity=30.5084745762712, Blast_Score=67, Evalue=2e-12, Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=35.3413654618474, Blast_Score=116, Evalue=1e-26, Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=35.2941176470588, Blast_Score=113, Evalue=1e-25, Organism=Drosophila melanogaster, GI21355319, Length=246, Percent_Identity=29.2682926829268, Blast_Score=105, Evalue=3e-23, Organism=Drosophila melanogaster, GI23397609, Length=243, Percent_Identity=31.2757201646091, Blast_Score=104, Evalue=7e-23, Organism=Drosophila melanogaster, GI21357041, Length=251, Percent_Identity=33.4661354581673, Blast_Score=102, Evalue=3e-22, Organism=Drosophila melanogaster, GI24643142, Length=240, Percent_Identity=30.4166666666667, Blast_Score=102, Evalue=3e-22, Organism=Drosophila melanogaster, GI24644337, Length=251, Percent_Identity=35.0597609561753, Blast_Score=101, Evalue=5e-22, Organism=Drosophila melanogaster, GI24639444, Length=253, Percent_Identity=32.8063241106719, Blast_Score=100, Evalue=9e-22, Organism=Drosophila melanogaster, GI24665247, Length=196, Percent_Identity=29.0816326530612, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI221331216, Length=196, Percent_Identity=29.0816326530612, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI24665243, Length=195, Percent_Identity=29.2307692307692, Blast_Score=78, Evalue=4e-15, Organism=Drosophila melanogaster, GI221331218, Length=195, Percent_Identity=29.2307692307692, Blast_Score=78, Evalue=5e-15, Organism=Drosophila melanogaster, GI17737361, Length=199, Percent_Identity=31.6582914572864, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24640442, Length=220, Percent_Identity=26.3636363636364, Blast_Score=67, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.69 [H]
Molecular weight: Translated: 26636; Mature: 26636
Theoretical pI: Translated: 5.77; Mature: 5.77
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 3.2 %Met (Translated Protein) 3.2 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 3.2 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKEIIDTFRPDLFAGRDILITGGSSGIGLAIAQGFARLGGTVIALGSSESKLKAAAADPE CHHHHHHHCCHHHCCCEEEEECCCCCCHHHHHHHHHHHCCEEEEECCCCCHHEECCCCCC NKGIRFERVDVRDPEMINAFAKTLGKLDVLINGAGIARPEAEFEDATYMEVMDVNLNSQM CCCEEEEEECCCCHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCHH RFAMAVLPLLKASRGVILNTASMLSYVSDPLVPAYGASKSGVLGLTRHLAHAFGPDGIRV HHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEE NAISPGYHKTDMTRGLWTDPVPAEKIAQRSALKRWGTVDDLVGTALFLASPAAEFITGAD EEECCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHCCCC LPVDGGFVVGSF CCCCCCEEEECC >Mature Secondary Structure MKEIIDTFRPDLFAGRDILITGGSSGIGLAIAQGFARLGGTVIALGSSESKLKAAAADPE CHHHHHHHCCHHHCCCEEEEECCCCCCHHHHHHHHHHHCCEEEEECCCCCHHEECCCCCC NKGIRFERVDVRDPEMINAFAKTLGKLDVLINGAGIARPEAEFEDATYMEVMDVNLNSQM CCCEEEEEECCCCHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCHH RFAMAVLPLLKASRGVILNTASMLSYVSDPLVPAYGASKSGVLGLTRHLAHAFGPDGIRV HHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEE NAISPGYHKTDMTRGLWTDPVPAEKIAQRSALKRWGTVDDLVGTALFLASPAAEFITGAD EEECCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHCCCC LPVDGGFVVGSF CCCCCCEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7751271 [H]