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The map label for this gene is xylB [H]

Identifier: 150397671

GI number: 150397671

Start: 2552388

End: 2553917

Strand: Direct

Name: xylB [H]

Synonym: Smed_2471

Alternate gene names: 150397671

Gene position: 2552388-2553917 (Clockwise)

Preceding gene: 150397670

Following gene: 150397672

Centisome position: 67.49

GC content: 66.01

Gene sequence:

>1530_bases
ATGACCGGGGAACTCTTTCTCGCAATCGACGTCGGCACCGGCAGCGTCCGGGCGGCGCTCATCGATGTCAGAGGAAAGAT
CGTCGAAATCGCAGCGCGCGAGCACGACCAGATCGTGCCGCAGTTCGGCTGGGCGGAGCAGCGGCCGCTCGATTGGTGGG
AGGGCGCCTGCCTTGCCATACGCAGCGTGCTCGACAAGACGGAAGGCGCGCGCGAACGCATCTCCATGATCGCCGTTTGC
GGCCAGATGCACGGCCTTGTCCTGCTCGACGACAGCGGGCAGTTGACGCGTGACACGGCGCCGCTCTGGAACGACAAGCG
TACGCTGGACCTCGTGCGCCGTTTCGAGGCCGGAAACGCGCCCGACAGCTATCTCCGCGAAAGCGGCAACACGCCGACGC
CGGCCTGGCCGGGATTCAAACTGCAATGGGTGCGCGATGCCGACCCTGAGGCCTACCGGCGCAGTGCAGTCGCCATGATG
CCGAAGGACTACATCAACTTCCGGCTGACGGGCGAGATCGCGATGGATACGGGCGACGCCTCTTGCAGTTTCCTGATGAA
CCCCGCAAACTTCGCCTGGTCGCCGGCGATGATCGAGCGCCTGGGGCTTGATGCCCGTCTCCTCCCGCCCATCCGCAATC
CGCTGGACATAATCGGCCGCATCACGGAACAGGCGGCCCAGGCGACGGGATTGAGCGCCGGCACGCCGGTCATGGTCGGC
GGGGCCGATTATCCGGTGGCGCTGCTCGGCTCGGGCGCCTGCCGGCCCGGCATGGGTTCGGACAGCACCGGCACAGGTGC
CATCGTTACGATGATTGCCGAAAAGCCCTTGCTGGATCCGGAAATTTCCAACGTCGCGACCATTGAAGGCAACTGGGCAC
CCTTCGTCCTTCTCGAGACGGGAGGCGACGGCATGCGCTGGGCCCGGCGCGCCTTTCATGACGGCGCGCTGAGCTACGGA
GACATCGTCGCGCGCGCGGAAGAAGCGCCGCCCGGCTGCGATGCCCTGCTGTTCATGCCGTTTCTCACCGGTGAGCGGCT
GGGCCGGCACCGCAATTCACGGGCGCAATTTTTCGGTCTCGGCGCGGGGCACGGCATGGAACATCTGCACCGGGCCATCC
TCGAAGGCATCGCCTTCGCCATGGCACGCCATATCCGCATCATGGAGCACAGCTCCGGCAAGCGCCTGGAGCGTATGATC
GCGGCCGGAGGTGGCGCCCGCACGAAGCTTTGGCTGAAGATCAAAGCAAGCGTCTTCAATACACCGGTTCTGGTGCCGCG
CGAGCCCGAATGCGGGCTCATGGGCTGCGCCGCCATGGCGGCGACCGCGACCGGCCGCTTCTCCCGCCCGGAGGAAGCTG
CGGATGCCTATGTCCGCTATGCGGACGAAATCGCCCCGGACTCGGCCTGGGCCGAAATCTACGGCCATGTCCAGCCGGTT
TTCGACCGGCTCTACCATCACAGCACGGCGCTCTATGACGACATGGATGCGCTTTCCGCCCGGATTCGCCAAGCCAGCGC
CGGGACCTGA

Upstream 100 bases:

>100_bases
CGCGCGCGGTCTATCGGGCCGCACTTGCTGCCTATCGCATTGCCGCTGAGCAGCAACGCGAGCTGTCCGGCGCACTCGTT
ACCTTGAGGGAGGCCGCAAC

Downstream 100 bases:

>100_bases
ACCACGACGATCATGCCTGAGGAGGAATTCATGAAAGAGATCATCGATACGTTTCGTCCAGACCTGTTTGCCGGCAGGGA
TATTCTGATTACCGGCGGTT

Product: carbohydrate kinase FGGY

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 509; Mature: 508

Protein sequence:

>509_residues
MTGELFLAIDVGTGSVRAALIDVRGKIVEIAAREHDQIVPQFGWAEQRPLDWWEGACLAIRSVLDKTEGARERISMIAVC
GQMHGLVLLDDSGQLTRDTAPLWNDKRTLDLVRRFEAGNAPDSYLRESGNTPTPAWPGFKLQWVRDADPEAYRRSAVAMM
PKDYINFRLTGEIAMDTGDASCSFLMNPANFAWSPAMIERLGLDARLLPPIRNPLDIIGRITEQAAQATGLSAGTPVMVG
GADYPVALLGSGACRPGMGSDSTGTGAIVTMIAEKPLLDPEISNVATIEGNWAPFVLLETGGDGMRWARRAFHDGALSYG
DIVARAEEAPPGCDALLFMPFLTGERLGRHRNSRAQFFGLGAGHGMEHLHRAILEGIAFAMARHIRIMEHSSGKRLERMI
AAGGGARTKLWLKIKASVFNTPVLVPREPECGLMGCAAMAATATGRFSRPEEAADAYVRYADEIAPDSAWAEIYGHVQPV
FDRLYHHSTALYDDMDALSARIRQASAGT

Sequences:

>Translated_509_residues
MTGELFLAIDVGTGSVRAALIDVRGKIVEIAAREHDQIVPQFGWAEQRPLDWWEGACLAIRSVLDKTEGARERISMIAVC
GQMHGLVLLDDSGQLTRDTAPLWNDKRTLDLVRRFEAGNAPDSYLRESGNTPTPAWPGFKLQWVRDADPEAYRRSAVAMM
PKDYINFRLTGEIAMDTGDASCSFLMNPANFAWSPAMIERLGLDARLLPPIRNPLDIIGRITEQAAQATGLSAGTPVMVG
GADYPVALLGSGACRPGMGSDSTGTGAIVTMIAEKPLLDPEISNVATIEGNWAPFVLLETGGDGMRWARRAFHDGALSYG
DIVARAEEAPPGCDALLFMPFLTGERLGRHRNSRAQFFGLGAGHGMEHLHRAILEGIAFAMARHIRIMEHSSGKRLERMI
AAGGGARTKLWLKIKASVFNTPVLVPREPECGLMGCAAMAATATGRFSRPEEAADAYVRYADEIAPDSAWAEIYGHVQPV
FDRLYHHSTALYDDMDALSARIRQASAGT
>Mature_508_residues
TGELFLAIDVGTGSVRAALIDVRGKIVEIAAREHDQIVPQFGWAEQRPLDWWEGACLAIRSVLDKTEGARERISMIAVCG
QMHGLVLLDDSGQLTRDTAPLWNDKRTLDLVRRFEAGNAPDSYLRESGNTPTPAWPGFKLQWVRDADPEAYRRSAVAMMP
KDYINFRLTGEIAMDTGDASCSFLMNPANFAWSPAMIERLGLDARLLPPIRNPLDIIGRITEQAAQATGLSAGTPVMVGG
ADYPVALLGSGACRPGMGSDSTGTGAIVTMIAEKPLLDPEISNVATIEGNWAPFVLLETGGDGMRWARRAFHDGALSYGD
IVARAEEAPPGCDALLFMPFLTGERLGRHRNSRAQFFGLGAGHGMEHLHRAILEGIAFAMARHIRIMEHSSGKRLERMIA
AGGGARTKLWLKIKASVFNTPVLVPREPECGLMGCAAMAATATGRFSRPEEAADAYVRYADEIAPDSAWAEIYGHVQPVF
DRLYHHSTALYDDMDALSARIRQASAGT

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=456, Percent_Identity=22.5877192982456, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI4504007, Length=456, Percent_Identity=22.5877192982456, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI189409120, Length=456, Percent_Identity=22.5877192982456, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI41393575, Length=457, Percent_Identity=23.8512035010941, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1787789, Length=514, Percent_Identity=27.6264591439689, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI1789987, Length=419, Percent_Identity=29.5942720763723, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1790005, Length=509, Percent_Identity=27.1119842829077, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI1790361, Length=473, Percent_Identity=24.5243128964059, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI1789168, Length=471, Percent_Identity=25.0530785562633, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1789138, Length=513, Percent_Identity=23.9766081871345, Blast_Score=105, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17535599, Length=455, Percent_Identity=24.1758241758242, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24655555, Length=507, Percent_Identity=25.8382642998028, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24655560, Length=507, Percent_Identity=25.8382642998028, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24655570, Length=507, Percent_Identity=25.8382642998028, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24655574, Length=507, Percent_Identity=25.8382642998028, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24655565, Length=507, Percent_Identity=25.8382642998028, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI17864214, Length=474, Percent_Identity=26.3713080168776, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24657106, Length=534, Percent_Identity=23.0337078651685, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24657102, Length=534, Percent_Identity=23.0337078651685, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24654573, Length=412, Percent_Identity=26.2135922330097, Blast_Score=84, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 55286; Mature: 55155

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGELFLAIDVGTGSVRAALIDVRGKIVEIAAREHDQIVPQFGWAEQRPLDWWEGACLAI
CCCCEEEEEECCCCCEEEEEEECCCCEEEEEHHHCCCCCCCCCCCCCCCCCHHHHHHHHH
RSVLDKTEGARERISMIAVCGQMHGLVLLDDSGQLTRDTAPLWNDKRTLDLVRRFEAGNA
HHHHHHCCCHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
PDSYLRESGNTPTPAWPGFKLQWVRDADPEAYRRSAVAMMPKDYINFRLTGEIAMDTGDA
CHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCC
SCSFLMNPANFAWSPAMIERLGLDARLLPPIRNPLDIIGRITEQAAQATGLSAGTPVMVG
CEEEEECCCCCCCCHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEC
GADYPVALLGSGACRPGMGSDSTGTGAIVTMIAEKPLLDPEISNVATIEGNWAPFVLLET
CCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCEEEEEE
GGDGMRWARRAFHDGALSYGDIVARAEEAPPGCDALLFMPFLTGERLGRHRNSRAQFFGL
CCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEC
GAGHGMEHLHRAILEGIAFAMARHIRIMEHSSGKRLERMIAAGGGARTKLWLKIKASVFN
CCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHCCCCCCEEEEEEEEEECCC
TPVLVPREPECGLMGCAAMAATATGRFSRPEEAADAYVRYADEIAPDSAWAEIYGHVQPV
CCEEECCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
FDRLYHHSTALYDDMDALSARIRQASAGT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TGELFLAIDVGTGSVRAALIDVRGKIVEIAAREHDQIVPQFGWAEQRPLDWWEGACLAI
CCCEEEEEECCCCCEEEEEEECCCCEEEEEHHHCCCCCCCCCCCCCCCCCHHHHHHHHH
RSVLDKTEGARERISMIAVCGQMHGLVLLDDSGQLTRDTAPLWNDKRTLDLVRRFEAGNA
HHHHHHCCCHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
PDSYLRESGNTPTPAWPGFKLQWVRDADPEAYRRSAVAMMPKDYINFRLTGEIAMDTGDA
CHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCC
SCSFLMNPANFAWSPAMIERLGLDARLLPPIRNPLDIIGRITEQAAQATGLSAGTPVMVG
CEEEEECCCCCCCCHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEC
GADYPVALLGSGACRPGMGSDSTGTGAIVTMIAEKPLLDPEISNVATIEGNWAPFVLLET
CCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCEEEEEE
GGDGMRWARRAFHDGALSYGDIVARAEEAPPGCDALLFMPFLTGERLGRHRNSRAQFFGL
CCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEC
GAGHGMEHLHRAILEGIAFAMARHIRIMEHSSGKRLERMIAAGGGARTKLWLKIKASVFN
CCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHCCCCCCEEEEEEEEEECCC
TPVLVPREPECGLMGCAAMAATATGRFSRPEEAADAYVRYADEIAPDSAWAEIYGHVQPV
CCEEECCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
FDRLYHHSTALYDDMDALSARIRQASAGT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1660563 [H]