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The map label for this gene is xylB [H]

Identifier: 150397670

GI number: 150397670

Start: 2550844

End: 2552391

Strand: Direct

Name: xylB [H]

Synonym: Smed_2470

Alternate gene names: 150397670

Gene position: 2550844-2552391 (Clockwise)

Preceding gene: 150397669

Following gene: 150397671

Centisome position: 67.45

GC content: 65.44

Gene sequence:

>1548_bases
ATGGGCGACACTGTTGCAGCATTCGACCTCGGAACCGGAGGCGTCAAGGCGGCGATCTTCCGTCCGGACGGGGTCTGCCT
TGCGGAAGAGGTCGTCTCCTATCGAACCTTTTATCCTTCATCCTCCTATCACGAGCAGCGCCCCGAAGACTGGTGGGACG
CGGTTTGCGCCAGTCTGCGAACCCTGCTCGGCAACCCAGCGGTGCTGGCCGACGAGATCCGCGCCGTCGCCATTTCCGGT
CACAGCCTCGGCTGCCTTCCACTCGACGAAGACGGCGTATTGCTGCAGGAATCCGTTCCGATCTGGTCCGACGGGCGGGC
CGTCGCAGAATCGGAGGATTTCTTCACGCGGGTCGACCCGGACGGCTGGTACAGGAAAACCGGCAACGGCTTTCCGGCCC
CGCTTTACACGGTGTTCAAGGCGATGTGGCTGCGCCGGAACGCGCCCGACATCTTCGTGCGGACACGGACGATCATCGGC
ACTAAGGATTACATCAATCTGCGGCTGACGGGCCGCATCGCCACCGATCCGTCCTATGCCTCGGGCACCGGCGTATACGA
TCTCCGGGCCGGGAGTTATGCACCCGACCTGATCGAAGCAGCGGGACTGAGCGCGGGCCTGTTTGCGCCGATCGTCGCCT
CCACCGATATCATCGGCGAGATCCTTCCCGAGATCGCTGACAGTCTCGGTCTCCCTCGAAGGGTGAAGGTCGTAGCCGGT
GGCGTGGACAACAGTTGCATGGCGCTCGGCGGCCGCACCTTCCTGGAAGGCGATGCCTATGCCTCGATGGGCTCGTCGAG
CTGGATCACCGTTTCCGCTTCGCAGCCGCTGCTCGACGACCGGGTCCGTCCCTTCGTTTTCGCCCATGTGGCGCCCGGCA
AGTTTATTTCGGCGACGTCAATCTTCTCCTCCGGCACCAGCGTGAACTGGGTTGCCGACACGTTGCTGCCGGACGTCAAG
CAGGCGGCCAGAGCCTCCGGTCTCGACGTTCATGACGCGCTGTTCCAGCTTGCCGGCGAGGCTCCGGCGGGCGCGCGCGG
GCTGATGTTCGTGCCGACGCTCGGCGGCGGCACCAGCTTCGAAGGCGGCCCAGCCGTGCGCGGCGGCTTCGTCGGCCTCG
ATCTGCAGCATGGCCGAGCGGATATATTCCGCGCGACGCTCGAAGGTGTGGCCCTCGGGCTTCGCGTCGCATTGGACGAG
CTGCGCCGCATGACGCCGATCGGCCCGGAAATGATCATCGTCGGTGGCGGCGCGCGCAGCCCATTCTGGCGGCAGGTTTT
CGCCGATGTCTTCGACTGCACGATCGTCAAGACAGGGATCGATCAGCAGGCGGCCGCCCTCGGCGCCGCGGCACTGGCCT
TCGTCGGCATGGGCCTGTGGCAGGATTTCCTGCCGATCCGGGTGCTGCACGTCGCAGAGGGACGCAATGAACCCGCGCCG
GAAGCGCGCGCGGTCTATCGGGCCGCACTTGCTGCCTATCGCATTGCCGCTGAGCAGCAACGCGAGCTGTCCGGCGCACT
CGTTACCTTGAGGGAGGCCGCAACATGA

Upstream 100 bases:

>100_bases
CGCTTCGGCATCAATACGCAGGTCGCCGTCGACCTCGTGCGCCAATGCGCCGCCCTGCCCGGCAGCCGCCTCGATATAGC
CGGCAAGGCGGATTGACGCC

Downstream 100 bases:

>100_bases
CCGGGGAACTCTTTCTCGCAATCGACGTCGGCACCGGCAGCGTCCGGGCGGCGCTCATCGATGTCAGAGGAAAGATCGTC
GAAATCGCAGCGCGCGAGCA

Product: carbohydrate kinase FGGY

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 515; Mature: 514

Protein sequence:

>515_residues
MGDTVAAFDLGTGGVKAAIFRPDGVCLAEEVVSYRTFYPSSSYHEQRPEDWWDAVCASLRTLLGNPAVLADEIRAVAISG
HSLGCLPLDEDGVLLQESVPIWSDGRAVAESEDFFTRVDPDGWYRKTGNGFPAPLYTVFKAMWLRRNAPDIFVRTRTIIG
TKDYINLRLTGRIATDPSYASGTGVYDLRAGSYAPDLIEAAGLSAGLFAPIVASTDIIGEILPEIADSLGLPRRVKVVAG
GVDNSCMALGGRTFLEGDAYASMGSSSWITVSASQPLLDDRVRPFVFAHVAPGKFISATSIFSSGTSVNWVADTLLPDVK
QAARASGLDVHDALFQLAGEAPAGARGLMFVPTLGGGTSFEGGPAVRGGFVGLDLQHGRADIFRATLEGVALGLRVALDE
LRRMTPIGPEMIIVGGGARSPFWRQVFADVFDCTIVKTGIDQQAAALGAAALAFVGMGLWQDFLPIRVLHVAEGRNEPAP
EARAVYRAALAAYRIAAEQQRELSGALVTLREAAT

Sequences:

>Translated_515_residues
MGDTVAAFDLGTGGVKAAIFRPDGVCLAEEVVSYRTFYPSSSYHEQRPEDWWDAVCASLRTLLGNPAVLADEIRAVAISG
HSLGCLPLDEDGVLLQESVPIWSDGRAVAESEDFFTRVDPDGWYRKTGNGFPAPLYTVFKAMWLRRNAPDIFVRTRTIIG
TKDYINLRLTGRIATDPSYASGTGVYDLRAGSYAPDLIEAAGLSAGLFAPIVASTDIIGEILPEIADSLGLPRRVKVVAG
GVDNSCMALGGRTFLEGDAYASMGSSSWITVSASQPLLDDRVRPFVFAHVAPGKFISATSIFSSGTSVNWVADTLLPDVK
QAARASGLDVHDALFQLAGEAPAGARGLMFVPTLGGGTSFEGGPAVRGGFVGLDLQHGRADIFRATLEGVALGLRVALDE
LRRMTPIGPEMIIVGGGARSPFWRQVFADVFDCTIVKTGIDQQAAALGAAALAFVGMGLWQDFLPIRVLHVAEGRNEPAP
EARAVYRAALAAYRIAAEQQRELSGALVTLREAAT
>Mature_514_residues
GDTVAAFDLGTGGVKAAIFRPDGVCLAEEVVSYRTFYPSSSYHEQRPEDWWDAVCASLRTLLGNPAVLADEIRAVAISGH
SLGCLPLDEDGVLLQESVPIWSDGRAVAESEDFFTRVDPDGWYRKTGNGFPAPLYTVFKAMWLRRNAPDIFVRTRTIIGT
KDYINLRLTGRIATDPSYASGTGVYDLRAGSYAPDLIEAAGLSAGLFAPIVASTDIIGEILPEIADSLGLPRRVKVVAGG
VDNSCMALGGRTFLEGDAYASMGSSSWITVSASQPLLDDRVRPFVFAHVAPGKFISATSIFSSGTSVNWVADTLLPDVKQ
AARASGLDVHDALFQLAGEAPAGARGLMFVPTLGGGTSFEGGPAVRGGFVGLDLQHGRADIFRATLEGVALGLRVALDEL
RRMTPIGPEMIIVGGGARSPFWRQVFADVFDCTIVKTGIDQQAAALGAAALAFVGMGLWQDFLPIRVLHVAEGRNEPAPE
ARAVYRAALAAYRIAAEQQRELSGALVTLREAAT

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI88196792, Length=527, Percent_Identity=21.2523719165085, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI41393575, Length=461, Percent_Identity=22.7765726681128, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI1789987, Length=493, Percent_Identity=29.2089249492901, Blast_Score=173, Evalue=3e-44,
Organism=Escherichia coli, GI1787789, Length=517, Percent_Identity=26.4990328820116, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1790005, Length=511, Percent_Identity=25.6360078277886, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1789168, Length=397, Percent_Identity=24.4332493702771, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1789138, Length=304, Percent_Identity=27.6315789473684, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI1790361, Length=488, Percent_Identity=20.6967213114754, Blast_Score=80, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17535599, Length=230, Percent_Identity=26.5217391304348, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI17864214, Length=482, Percent_Identity=21.1618257261411, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 54725; Mature: 54594

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00445 FGGY_KINASES_2 ; PS00120 LIPASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDTVAAFDLGTGGVKAAIFRPDGVCLAEEVVSYRTFYPSSSYHEQRPEDWWDAVCASLR
CCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
TLLGNPAVLADEIRAVAISGHSLGCLPLDEDGVLLQESVPIWSDGRAVAESEDFFTRVDP
HHHCCCCEECCCCEEEEECCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCCCCEEEECC
DGWYRKTGNGFPAPLYTVFKAMWLRRNAPDIFVRTRTIIGTKDYINLRLTGRIATDPSYA
CCCEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCEEEEEEEEEEECCCCCC
SGTGVYDLRAGSYAPDLIEAAGLSAGLFAPIVASTDIIGEILPEIADSLGLPRRVKVVAG
CCCCEEEECCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEC
GVDNSCMALGGRTFLEGDAYASMGSSSWITVSASQPLLDDRVRPFVFAHVAPGKFISATS
CCCCCCEEECCCEEECCCCHHCCCCCCEEEEECCCCCHHHCCCCEEEEEECCCCEEEHHH
IFSSGTSVNWVADTLLPDVKQAARASGLDVHDALFQLAGEAPAGARGLMFVPTLGGGTSF
HHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCEEEEEECCCCCCC
EGGPAVRGGFVGLDLQHGRADIFRATLEGVALGLRVALDELRRMTPIGPEMIIVGGGARS
CCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCC
PFWRQVFADVFDCTIVKTGIDQQAAALGAAALAFVGMGLWQDFLPIRVLHVAEGRNEPAP
HHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCH
EARAVYRAALAAYRIAAEQQRELSGALVTLREAAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHCC
>Mature Secondary Structure 
GDTVAAFDLGTGGVKAAIFRPDGVCLAEEVVSYRTFYPSSSYHEQRPEDWWDAVCASLR
CCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
TLLGNPAVLADEIRAVAISGHSLGCLPLDEDGVLLQESVPIWSDGRAVAESEDFFTRVDP
HHHCCCCEECCCCEEEEECCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCCCCEEEECC
DGWYRKTGNGFPAPLYTVFKAMWLRRNAPDIFVRTRTIIGTKDYINLRLTGRIATDPSYA
CCCEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCEEEEEEEEEEECCCCCC
SGTGVYDLRAGSYAPDLIEAAGLSAGLFAPIVASTDIIGEILPEIADSLGLPRRVKVVAG
CCCCEEEECCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEC
GVDNSCMALGGRTFLEGDAYASMGSSSWITVSASQPLLDDRVRPFVFAHVAPGKFISATS
CCCCCCEEECCCEEECCCCHHCCCCCCEEEEECCCCCHHHCCCCEEEEEECCCCEEEHHH
IFSSGTSVNWVADTLLPDVKQAARASGLDVHDALFQLAGEAPAGARGLMFVPTLGGGTSF
HHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCEEEEEECCCCCCC
EGGPAVRGGFVGLDLQHGRADIFRATLEGVALGLRVALDELRRMTPIGPEMIIVGGGARS
CCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCC
PFWRQVFADVFDCTIVKTGIDQQAAALGAAALAFVGMGLWQDFLPIRVLHVAEGRNEPAP
HHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCH
EARAVYRAALAAYRIAAEQQRELSGALVTLREAAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2994009 [H]