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The map label for this gene is pgiA

Identifier: 150397663

GI number: 150397663

Start: 2545026

End: 2545670

Strand: Direct

Name: pgiA

Synonym: Smed_2463

Alternate gene names: 150397663

Gene position: 2545026-2545670 (Clockwise)

Preceding gene: 150397662

Following gene: 150397664

Centisome position: 67.29

GC content: 61.4

Gene sequence:

>645_bases
TTGACAAAGCTATTCGAGCCCGCAGCGTGCCAGGTCGACCTTCGGACCGGAGCCATGAGCGCTGCGACCGGCGCTTACCA
GAAACGCTTCCGCGATCTTGCCGGCCTCTATGCGGATGAGGCGGCTTTCTCTGCAATGCGGGAAAACTGGAACGACACGG
TTGTCTACGAGGTTTCGGAGTTCCGCCCCAACGAACGCTCCGGAGACCTCATCTTCGGTACGACGCGTATGCTGCCCGGC
AAGGTGGGCGATGAGTATTTCGTCACCCGCGGCCACATCCATAGACAGTCGGACCGGCCGGAAATCTATTACGGGCAAAA
GGGCAGCGGCCTGATGCTCCTGGAATCGCCGGAGGGCGAAGTGCGTATCGTGGCCATCGACGCCCGGACGGTCTGCTACG
TCCCGCCTTACTGGATCCACCGTTCGGTGAACATCGGAGGCGAGGAGCTGGTGATGCTCTTCTGTTATCCGGCCGATTCC
GGCCAGGACTACGATTGCATCGCCAAGGCCGGCGGCATGCGGGTCCGCATCGTCGATGACGGCGAAGGCGGCTGGAAACA
GGTGGATAACAGCAGCTGGCGAAAGCGCGATGCGGCAACCATCGCCGCCCTTTACGGCCTGGAGAAGAAGGAGAAATCCG
CATGA

Upstream 100 bases:

>100_bases
CGCCAGCGGCGCGGCTGCGATGGTGAACGGCGCGAACCTTAAGATCGACGGCGGTTACACCATCGCCTGATACCAAAAGC
GACACATACGAGGAACCACT

Downstream 100 bases:

>100_bases
ATGCCCCATTCGATCACGCCGCGAAGCTTGGCATCGTTCCCGTGATTGCGATCGAGCGCGCGTCCGACGCCATCGCTCTG
GCTGACGCGCTTCTCGAAGG

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI

Number of amino acids: Translated: 214; Mature: 213

Protein sequence:

>214_residues
MTKLFEPAACQVDLRTGAMSAATGAYQKRFRDLAGLYADEAAFSAMRENWNDTVVYEVSEFRPNERSGDLIFGTTRMLPG
KVGDEYFVTRGHIHRQSDRPEIYYGQKGSGLMLLESPEGEVRIVAIDARTVCYVPPYWIHRSVNIGGEELVMLFCYPADS
GQDYDCIAKAGGMRVRIVDDGEGGWKQVDNSSWRKRDAATIAALYGLEKKEKSA

Sequences:

>Translated_214_residues
MTKLFEPAACQVDLRTGAMSAATGAYQKRFRDLAGLYADEAAFSAMRENWNDTVVYEVSEFRPNERSGDLIFGTTRMLPG
KVGDEYFVTRGHIHRQSDRPEIYYGQKGSGLMLLESPEGEVRIVAIDARTVCYVPPYWIHRSVNIGGEELVMLFCYPADS
GQDYDCIAKAGGMRVRIVDDGEGGWKQVDNSSWRKRDAATIAALYGLEKKEKSA
>Mature_213_residues
TKLFEPAACQVDLRTGAMSAATGAYQKRFRDLAGLYADEAAFSAMRENWNDTVVYEVSEFRPNERSGDLIFGTTRMLPGK
VGDEYFVTRGHIHRQSDRPEIYYGQKGSGLMLLESPEGEVRIVAIDARTVCYVPPYWIHRSVNIGGEELVMLFCYPADSG
QDYDCIAKAGGMRVRIVDDGEGGWKQVDNSSWRKRDAATIAALYGLEKKEKSA

Specific function: Unknown

COG id: COG2140

COG function: function code GR; Thermophilic glucose-6-phosphate isomerase and related metalloenzymes

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal-type GPI family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPI_SINMW (A6UCB5)

Other databases:

- EMBL:   CP000738
- RefSeq:   YP_001328130.1
- ProteinModelPortal:   A6UCB5
- SMR:   A6UCB5
- STRING:   A6UCB5
- GeneID:   5323324
- GenomeReviews:   CP000738_GR
- KEGG:   smd:Smed_2463
- eggNOG:   COG2140
- HOGENOM:   HBG725476
- OMA:   YPADAGH
- ProtClustDB:   PRK04190
- BioCyc:   SMED366394:SMED_2463-MONOMER
- GO:   GO:0005737
- GO:   GO:0006094
- GO:   GO:0006096
- HAMAP:   MF_01410
- InterPro:   IPR011051
- InterPro:   IPR010551
- InterPro:   IPR016758
- InterPro:   IPR014710
- Gene3D:   G3DSA:2.60.120.10
- PIRSF:   PIRSF019325

Pfam domain/function: PF06560 GPI; SSF51182 RmlC_like_cupin

EC number: =5.3.1.9

Molecular weight: Translated: 23911; Mature: 23780

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLFEPAACQVDLRTGAMSAATGAYQKRFRDLAGLYADEAAFSAMRENWNDTVVYEVSE
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHH
FRPNERSGDLIFGTTRMLPGKVGDEYFVTRGHIHRQSDRPEIYYGQKGSGLMLLESPEGE
CCCCCCCCCEEEEEEECCCCCCCCCEEEECCEEECCCCCCCEEECCCCCCEEEEECCCCC
VRIVAIDARTVCYVPPYWIHRSVNIGGEELVMLFCYPADSGQDYDCIAKAGGMRVRIVDD
EEEEEECCCEEEEECCHHHEEEECCCCCEEEEEEEEECCCCCCHHHHCCCCCCEEEEEEC
GEGGWKQVDNSSWRKRDAATIAALYGLEKKEKSA
CCCCCCCCCCCCCHHHHHHHHHHHHCCCHHCCCC
>Mature Secondary Structure 
TKLFEPAACQVDLRTGAMSAATGAYQKRFRDLAGLYADEAAFSAMRENWNDTVVYEVSE
CCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHH
FRPNERSGDLIFGTTRMLPGKVGDEYFVTRGHIHRQSDRPEIYYGQKGSGLMLLESPEGE
CCCCCCCCCEEEEEEECCCCCCCCCEEEECCEEECCCCCCCEEECCCCCCEEEEECCCCC
VRIVAIDARTVCYVPPYWIHRSVNIGGEELVMLFCYPADSGQDYDCIAKAGGMRVRIVDD
EEEEEECCCEEEEECCHHHEEEECCCCCEEEEEEEEECCCCCCHHHHCCCCCCEEEEEEC
GEGGWKQVDNSSWRKRDAATIAALYGLEKKEKSA
CCCCCCCCCCCCCHHHHHHHHHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA