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The map label for this gene is eda [H]

Identifier: 150397664

GI number: 150397664

Start: 2545667

End: 2546320

Strand: Direct

Name: eda [H]

Synonym: Smed_2464

Alternate gene names: 150397664

Gene position: 2545667-2546320 (Clockwise)

Preceding gene: 150397663

Following gene: 150397665

Centisome position: 67.31

GC content: 66.21

Gene sequence:

>654_bases
ATGAATGCCCCATTCGATCACGCCGCGAAGCTTGGCATCGTTCCCGTGATTGCGATCGAGCGCGCGTCCGACGCCATCGC
TCTGGCTGACGCGCTTCTCGAAGGCGGGTTGCCGCTGGCAGAGATTACCTTCCGCACAGTAGCCGCCGCCGAGGTCATTG
CGATCATGGCCGAGAAGCGGCCGGAACTGCTGGTTGGCGCCGGGACGATTCTGACACCCGAAGCACTGGCAGCAGCGATC
GGTGCGGGCGCGCGCTTCGGGCTCGCGCCCGGCTTCGACGCCGAGATCGTCGCGGCCGCGAAGACCAGGAATTTTCCCTT
TGCCCCCGGCATCATGACGCCGTCGGACCTGACGGCCGTGTCGCGTAAAGGCCTCAAGCTTGCAAAGTTCTTTCCCGCAA
AGGCGGCCGGCGGCCCGGCCATGCTGGAGGCGATAAGTGCGCCTTTCGCCCATCTCGGCACACGCTTCGTACCGACGGGC
GGCGTCAGCATCGACAACATGCATGAATGGCTGAAGCTCGGCGCGGTGGCCGCCGTCGGCGGCACCTGGATCGCGACGAA
GGCCGATATAGGCGAAGGCCGCTGGACCGACATCACGGCAAAGGCGCGCGCAGCAGTCGCACGGGCCAGGGACGTACGCG
AGGCGAACCGATGA

Upstream 100 bases:

>100_bases
GCGAAGGCGGCTGGAAACAGGTGGATAACAGCAGCTGGCGAAAGCGCGATGCGGCAACCATCGCCGCCCTTTACGGCCTG
GAGAAGAAGGAGAAATCCGC

Downstream 100 bases:

>100_bases
GCCGCTACCAGCCCGCAACCCAGCCAAGCTTTTATTTCATCGGCGTGACGACGGCGAAAAGCTCGATCATGCGGGTCTTC
CCCGCCTGGGCGCGCCATCT

Product: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase

Products: NA

Alternate protein names: KDPG-aldolase; Phospho-2-dehydro-3-deoxygluconate aldolase; Phospho-2-keto-3-deoxygluconate aldolase [H]

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MNAPFDHAAKLGIVPVIAIERASDAIALADALLEGGLPLAEITFRTVAAAEVIAIMAEKRPELLVGAGTILTPEALAAAI
GAGARFGLAPGFDAEIVAAAKTRNFPFAPGIMTPSDLTAVSRKGLKLAKFFPAKAAGGPAMLEAISAPFAHLGTRFVPTG
GVSIDNMHEWLKLGAVAAVGGTWIATKADIGEGRWTDITAKARAAVARARDVREANR

Sequences:

>Translated_217_residues
MNAPFDHAAKLGIVPVIAIERASDAIALADALLEGGLPLAEITFRTVAAAEVIAIMAEKRPELLVGAGTILTPEALAAAI
GAGARFGLAPGFDAEIVAAAKTRNFPFAPGIMTPSDLTAVSRKGLKLAKFFPAKAAGGPAMLEAISAPFAHLGTRFVPTG
GVSIDNMHEWLKLGAVAAVGGTWIATKADIGEGRWTDITAKARAAVARARDVREANR
>Mature_217_residues
MNAPFDHAAKLGIVPVIAIERASDAIALADALLEGGLPLAEITFRTVAAAEVIAIMAEKRPELLVGAGTILTPEALAAAI
GAGARFGLAPGFDAEIVAAAKTRNFPFAPGIMTPSDLTAVSRKGLKLAKFFPAKAAGGPAMLEAISAPFAHLGTRFVPTG
GVSIDNMHEWLKLGAVAAVGGTWIATKADIGEGRWTDITAKARAAVARARDVREANR

Specific function: KEY ENZYME IN THE ENTNER-DOUDOROFF PATHWAY. PARTICIPATES IN THE REGULATION OF THE INTRACELLULAR LEVEL OF GLYOXYLATE. [C]

COG id: COG0800

COG function: function code G; 2-keto-3-deoxy-6-phosphogluconate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KHG/KDPG aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1788156, Length=186, Percent_Identity=41.3978494623656, Blast_Score=135, Evalue=1e-33,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000887
- InterPro:   IPR013785 [H]

Pfam domain/function: PF01081 Aldolase [H]

EC number: =4.1.2.14 [H]

Molecular weight: Translated: 22299; Mature: 22299

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS00159 ALDOLASE_KDPG_KHG_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPFDHAAKLGIVPVIAIERASDAIALADALLEGGLPLAEITFRTVAAAEVIAIMAEKR
CCCCCCHHHHCCCEEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
PELLVGAGTILTPEALAAAIGAGARFGLAPGFDAEIVAAAKTRNFPFAPGIMTPSDLTAV
CCEEEECCCEECHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHH
SRKGLKLAKFFPAKAAGGPAMLEAISAPFAHLGTRFVPTGGVSIDNMHEWLKLGAVAAVG
HHCCCCHHHHCCCCCCCCHHHHHHHHCCHHHHCCEECCCCCCCHHHHHHHHHHHHHHHCC
GTWIATKADIGEGRWTDITAKARAAVARARDVREANR
CEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNAPFDHAAKLGIVPVIAIERASDAIALADALLEGGLPLAEITFRTVAAAEVIAIMAEKR
CCCCCCHHHHCCCEEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
PELLVGAGTILTPEALAAAIGAGARFGLAPGFDAEIVAAAKTRNFPFAPGIMTPSDLTAV
CCEEEECCCEECHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHH
SRKGLKLAKFFPAKAAGGPAMLEAISAPFAHLGTRFVPTGGVSIDNMHEWLKLGAVAAVG
HHCCCCHHHHCCCCCCCCHHHHHHHHCCHHHHCCEECCCCCCCHHHHHHHHHHHHHHHCC
GTWIATKADIGEGRWTDITAKARAAVARARDVREANR
CEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]