The gene/protein map for NC_009636 is currently unavailable.
Definition Sinorhizobium medicae WSM419 chromosome, complete genome.
Accession NC_009636
Length 3,781,904

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The map label for this gene is kduD [H]

Identifier: 150397648

GI number: 150397648

Start: 2530702

End: 2531493

Strand: Reverse

Name: kduD [H]

Synonym: Smed_2448

Alternate gene names: 150397648

Gene position: 2531493-2530702 (Counterclockwise)

Preceding gene: 150397649

Following gene: 150397647

Centisome position: 66.94

GC content: 67.55

Gene sequence:

>792_bases
ATGTCGACCAGTTCATCCGCTGACGGGCGGACCCGCGCGACCGGCAGTCCCGCCGCCTTCCTGCGCCCCGGCCTTTTCGA
AGGGCGGCAGGTGCTGGTGAGCGGCGGGACCTCAGGTATCGGCGCTGCGATCTGCGAGGCCTTCGCCGCGCTCGGGGCCG
ATGTCCTCGCAACGGGCATCACCGAGGCGGAGATTGCCGCCGCCGGAAGCCGGCCCGGACTTCAGGACGTGCAGTTCGCC
ACGCTCGACGTGCGCGACAGGTCTGCCGTGGATGCTCTGGTCGCCGGCCTGCCGCGGCTGGACCACGTGGTGAACTGCGC
CGGCGTGATCCGCCGCAATGACGAACTCGAGCCGGATGTGTTCGCCGACGTCGTCGATATCAATCTCAACGGCTCCATGC
GCGTCTGCGCGGCAGCCCGTCCACGGCTTGCGGAAACCGGCGGCACGATCGTCAATACCGCCTCCATGCTGTCGTTCTTC
GGCGGTGGCCTGGTGCCCGGCTATTCCGCATCGAAGGGCGGCATCGCCCAGCTCACCAAATCGCTGGCGATCGCCTATGC
GGCCGATGCAATCCGGGTGAATGCCATCGCGCCGGGTTGGATCGCGACACCCCTGACGAAGGCGCTACGGGAGAGCCCGG
AGCGCAACGCGGCCATTCTCGGCCGCACGCCGCTCAATCGCTGGGGAGAGCCGGCGGAAGTCGCCGGTGGCGTTCTTTAT
CTGTCCTCGCCGCTTGCAAGCTTCGTTACCGGCAGCGTGCTGGTCATCGATGGCGGCTATCTGATCATGTGA

Upstream 100 bases:

>100_bases
TATGTCGACGCCTTCGGCGAGCCGCTCGGCTTCGAGGACGTCTTCACCAAGATCGATATGTGTCGCGCGCATTACGAAGC
GGTCGGACTGGGGGCGGATT

Downstream 100 bases:

>100_bases
GGCACGATATGAAAGCCATTGTTCTCCCCGGACCGCAGGCGCAAATTGACAACGTGACACTGACCGACCTGCCGACCCCG
GAGCCCGGGCCGGGCGAACT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 2-keto-3-deoxygluconate 5-dehydrogenase; 2-keto-3-deoxygluconate oxidoreductase; KDG oxidoreductase [H]

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MSTSSSADGRTRATGSPAAFLRPGLFEGRQVLVSGGTSGIGAAICEAFAALGADVLATGITEAEIAAAGSRPGLQDVQFA
TLDVRDRSAVDALVAGLPRLDHVVNCAGVIRRNDELEPDVFADVVDINLNGSMRVCAAARPRLAETGGTIVNTASMLSFF
GGGLVPGYSASKGGIAQLTKSLAIAYAADAIRVNAIAPGWIATPLTKALRESPERNAAILGRTPLNRWGEPAEVAGGVLY
LSSPLASFVTGSVLVIDGGYLIM

Sequences:

>Translated_263_residues
MSTSSSADGRTRATGSPAAFLRPGLFEGRQVLVSGGTSGIGAAICEAFAALGADVLATGITEAEIAAAGSRPGLQDVQFA
TLDVRDRSAVDALVAGLPRLDHVVNCAGVIRRNDELEPDVFADVVDINLNGSMRVCAAARPRLAETGGTIVNTASMLSFF
GGGLVPGYSASKGGIAQLTKSLAIAYAADAIRVNAIAPGWIATPLTKALRESPERNAAILGRTPLNRWGEPAEVAGGVLY
LSSPLASFVTGSVLVIDGGYLIM
>Mature_262_residues
STSSSADGRTRATGSPAAFLRPGLFEGRQVLVSGGTSGIGAAICEAFAALGADVLATGITEAEIAAAGSRPGLQDVQFAT
LDVRDRSAVDALVAGLPRLDHVVNCAGVIRRNDELEPDVFADVVDINLNGSMRVCAAARPRLAETGGTIVNTASMLSFFG
GGLVPGYSASKGGIAQLTKSLAIAYAADAIRVNAIAPGWIATPLTKALRESPERNAAILGRTPLNRWGEPAEVAGGVLYL
SSPLASFVTGSVLVIDGGYLIM

Specific function: Catalyzes the reduction of 2,5-diketo-3-deoxygluconate (DKII or 4,6-dihydroxy-2,5-dioxohexanoate) into 2-keto-3- deoxygluconate (KDG or 2-dehydro-3-deoxygluconate) with a concomitant oxidation of NADH [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=242, Percent_Identity=37.603305785124, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI10190704, Length=254, Percent_Identity=33.4645669291339, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI66933014, Length=246, Percent_Identity=31.7073170731707, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI7705925, Length=241, Percent_Identity=29.8755186721992, Blast_Score=94, Evalue=9e-20,
Organism=Homo sapiens, GI19923817, Length=264, Percent_Identity=29.1666666666667, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI59889578, Length=192, Percent_Identity=34.375, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI15277342, Length=252, Percent_Identity=30.5555555555556, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI4758504, Length=254, Percent_Identity=32.2834645669291, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI32483357, Length=240, Percent_Identity=31.25, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI4503301, Length=258, Percent_Identity=27.5193798449612, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=26.0162601626016, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI83715985, Length=255, Percent_Identity=30.1960784313725, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1789208, Length=251, Percent_Identity=37.4501992031873, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI87082160, Length=247, Percent_Identity=32.3886639676113, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1790717, Length=245, Percent_Identity=33.8775510204082, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=33.8775510204082, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=33.4615384615385, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=31.8548387096774, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=29.8804780876494, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1789378, Length=257, Percent_Identity=31.1284046692607, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788459, Length=246, Percent_Identity=28.8617886178862, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI2367365, Length=250, Percent_Identity=32.4, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787905, Length=250, Percent_Identity=28.4, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787820, Length=180, Percent_Identity=30, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=258, Percent_Identity=34.1085271317829, Blast_Score=117, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=33.3333333333333, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=32.2709163346614, Blast_Score=107, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI71994604, Length=249, Percent_Identity=32.5301204819277, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=29.3172690763052, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17538182, Length=250, Percent_Identity=30, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17544670, Length=260, Percent_Identity=27.3076923076923, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17536025, Length=266, Percent_Identity=28.9473684210526, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17536651, Length=255, Percent_Identity=29.4117647058824, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17560676, Length=241, Percent_Identity=29.4605809128631, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=27.3764258555133, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=244, Percent_Identity=27.4590163934426, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=265, Percent_Identity=28.6792452830189, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=258, Percent_Identity=25.1937984496124, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=26.5384615384615, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17561272, Length=263, Percent_Identity=30.4182509505703, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562910, Length=266, Percent_Identity=27.0676691729323, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=258, Percent_Identity=26.3565891472868, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=256, Percent_Identity=27.34375, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=262, Percent_Identity=25.5725190839695, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=260, Percent_Identity=24.6153846153846, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=28.030303030303, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=258, Percent_Identity=25.968992248062, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=27.4809160305344, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=260, Percent_Identity=28.0769230769231, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=266, Percent_Identity=28.1954887218045, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=269, Percent_Identity=25.6505576208178, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=265, Percent_Identity=26.7924528301887, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=263, Percent_Identity=23.9543726235741, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=273, Percent_Identity=32.2344322344322, Blast_Score=111, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6322861, Length=192, Percent_Identity=29.1666666666667, Blast_Score=73, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24643142, Length=235, Percent_Identity=33.6170212765957, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI23397609, Length=244, Percent_Identity=32.7868852459016, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=31.5789473684211, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21357041, Length=260, Percent_Identity=32.6923076923077, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=31.6205533596838, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21355319, Length=251, Percent_Identity=29.8804780876494, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24644339, Length=261, Percent_Identity=31.0344827586207, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24644337, Length=171, Percent_Identity=35.0877192982456, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17737361, Length=254, Percent_Identity=32.2834645669291, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011286
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.127 [H]

Molecular weight: Translated: 26825; Mature: 26694

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MSTSSSADGRTRATGSPAAFLRPGLFEGRQVLVSGGTSGIGAAICEAFAALGADVLATGI
CCCCCCCCCCCCCCCCCHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCHHHHHHCC
TEAEIAAAGSRPGLQDVQFATLDVRDRSAVDALVAGLPRLDHVVNCAGVIRRNDELEPDV
CHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCC
FADVVDINLNGSMRVCAAARPRLAETGGTIVNTASMLSFFGGGLVPGYSASKGGIAQLTK
EEEEEEEECCCCEEEEECCCCCHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
SLAIAYAADAIRVNAIAPGWIATPLTKALRESPERNAAILGRTPLNRWGEPAEVAGGVLY
HHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCCCCCEEEECCCHHHCCCHHHHHCCEEE
LSSPLASFVTGSVLVIDGGYLIM
EHHHHHHHHCCCEEEEECCEEEC
>Mature Secondary Structure 
STSSSADGRTRATGSPAAFLRPGLFEGRQVLVSGGTSGIGAAICEAFAALGADVLATGI
CCCCCCCCCCCCCCCCHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCHHHHHHCC
TEAEIAAAGSRPGLQDVQFATLDVRDRSAVDALVAGLPRLDHVVNCAGVIRRNDELEPDV
CHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCC
FADVVDINLNGSMRVCAAARPRLAETGGTIVNTASMLSFFGGGLVPGYSASKGGIAQLTK
EEEEEEEECCCCEEEEECCCCCHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
SLAIAYAADAIRVNAIAPGWIATPLTKALRESPERNAAILGRTPLNRWGEPAEVAGGVLY
HHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCCCCCEEEECCCHHHCCCHHHHHCCEEE
LSSPLASFVTGSVLVIDGGYLIM
EHHHHHHHHCCCEEEEECCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]