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The map label for this gene is dppB [C]

Identifier: 150397640

GI number: 150397640

Start: 2520503

End: 2521447

Strand: Reverse

Name: dppB [C]

Synonym: Smed_2440

Alternate gene names: 150397640

Gene position: 2521447-2520503 (Counterclockwise)

Preceding gene: 150397641

Following gene: 150397639

Centisome position: 66.67

GC content: 61.27

Gene sequence:

>945_bases
ATGCTACGTTTCATCCTGAGCCGTCTGGCGATGGCGATCCCGACGGTCGTCCTCGTCTCCGTGACGGTCTTTGCACTGAT
CCGGTTCATTCCCGGTGATCCCGCCGCGCTGATGCTGGGTGATATGGCTCAGCCCGATCAGATCGCCGCGATGCGGGTGG
AACTCGGCCTCGACAGGTCCATGCCGCAGCAGTTCCTGATCTGGGCCGGTGATGTGCTGCGCGGCGACTTCGGCCGCTCG
ATCGTCAATGACGAGGCGGTGCTGCCGCTGGTCGTTTCCCGCTTTCTGGTAAGCGCGGAAATCGTCGTCGTCGCGGTCTT
ACTGGCAAGCCTGATTGCCGTACCGGCCGGCGTAATCGCCGCCTGGCGTCAAAACAGCCTGACGGATCTGGCTCTGGTCG
GAACGGCAACCGTTCTCCTTTCCATCCCCACCTTCTGGCTCGGCCTGCTCCTGCTCCTGCTTTTCGGGCTCAAACTCGGA
TGGCTGCCGGTTCTCGGCTATGTCTCGATCAGCGACAATCTGGTGGACGGTTTGCTTTATCTCGTTCTGCCTGTCGTGAC
GCTGGTCATCCATGAAGCGGGTGTCCTGATCCGTATGGCGCGTGCCTCCACGCTGGAGGTGCTGCGTCTCGATTACATCA
CCCACGCCCGCGCCAAAGGGCTCTCGGAAGGCGCCGTGCTCTGGCGCCATGCCTTCAAGAACGCCTTCGGTCCGACCTGG
ACGATGATCGGCCTCATCCTCGGCAATCTGCTCGGGGGCATCGCCGTCATCGAAACGGTCTTCACCATACCGGGGCTCGG
GCGTCTGATGGTGGACAGTATTTTCGCGCGTGACTACCCGGTCATCCAGGGATGCCTTCTGTTCGTCGCGCTCTCCTATG
TGCTGGTCAACCTCGTCATCGACCTTCTTTATCCTCTCTTCGATCCGCGTGTTGTCGCCGAATGA

Upstream 100 bases:

>100_bases
AATATGCATAATATTGCGCGCCAATCTCCATTCCCTCATAGTTTGGACCAACGAAACCGGTGAGGCCAATCCCCAGTCGG
CTCTCAATCGTGGGGAAGCA

Downstream 100 bases:

>100_bases
AAAAGCTCACCCTCAACGGACTGATCGGTGGCATCCTGATCGCTGTCCTGCTCGTCACCGCTGCTGTCGGTCTCTTCTGG
ACGCCCTTCGATCCGATGAA

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MLRFILSRLAMAIPTVVLVSVTVFALIRFIPGDPAALMLGDMAQPDQIAAMRVELGLDRSMPQQFLIWAGDVLRGDFGRS
IVNDEAVLPLVVSRFLVSAEIVVVAVLLASLIAVPAGVIAAWRQNSLTDLALVGTATVLLSIPTFWLGLLLLLLFGLKLG
WLPVLGYVSISDNLVDGLLYLVLPVVTLVIHEAGVLIRMARASTLEVLRLDYITHARAKGLSEGAVLWRHAFKNAFGPTW
TMIGLILGNLLGGIAVIETVFTIPGLGRLMVDSIFARDYPVIQGCLLFVALSYVLVNLVIDLLYPLFDPRVVAE

Sequences:

>Translated_314_residues
MLRFILSRLAMAIPTVVLVSVTVFALIRFIPGDPAALMLGDMAQPDQIAAMRVELGLDRSMPQQFLIWAGDVLRGDFGRS
IVNDEAVLPLVVSRFLVSAEIVVVAVLLASLIAVPAGVIAAWRQNSLTDLALVGTATVLLSIPTFWLGLLLLLLFGLKLG
WLPVLGYVSISDNLVDGLLYLVLPVVTLVIHEAGVLIRMARASTLEVLRLDYITHARAKGLSEGAVLWRHAFKNAFGPTW
TMIGLILGNLLGGIAVIETVFTIPGLGRLMVDSIFARDYPVIQGCLLFVALSYVLVNLVIDLLYPLFDPRVVAE
>Mature_314_residues
MLRFILSRLAMAIPTVVLVSVTVFALIRFIPGDPAALMLGDMAQPDQIAAMRVELGLDRSMPQQFLIWAGDVLRGDFGRS
IVNDEAVLPLVVSRFLVSAEIVVVAVLLASLIAVPAGVIAAWRQNSLTDLALVGTATVLLSIPTFWLGLLLLLLFGLKLG
WLPVLGYVSISDNLVDGLLYLVLPVVTLVIHEAGVLIRMARASTLEVLRLDYITHARAKGLSEGAVLWRHAFKNAFGPTW
TMIGLILGNLLGGIAVIETVFTIPGLGRLMVDSIFARDYPVIQGCLLFVALSYVLVNLVIDLLYPLFDPRVVAE

Specific function: Probably part of the binding-protein-dependent transport system y4tOPQRS for a peptide. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=335, Percent_Identity=39.4029850746269, Blast_Score=224, Evalue=7e-60,
Organism=Escherichia coli, GI1787053, Length=311, Percent_Identity=40.8360128617363, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI1789888, Length=314, Percent_Identity=36.3057324840764, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1787497, Length=313, Percent_Identity=33.8658146964856, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1787761, Length=315, Percent_Identity=38.4126984126984, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1787550, Length=278, Percent_Identity=29.8561151079137, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1788504, Length=367, Percent_Identity=28.0653950953678, Blast_Score=125, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34017; Mature: 34017

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRFILSRLAMAIPTVVLVSVTVFALIRFIPGDPAALMLGDMAQPDQIAAMRVELGLDRS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHCCCCC
MPQQFLIWAGDVLRGDFGRSIVNDEAVLPLVVSRFLVSAEIVVVAVLLASLIAVPAGVIA
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWRQNSLTDLALVGTATVLLSIPTFWLGLLLLLLFGLKLGWLPVLGYVSISDNLVDGLLY
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVLPVVTLVIHEAGVLIRMARASTLEVLRLDYITHARAKGLSEGAVLWRHAFKNAFGPTW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHH
TMIGLILGNLLGGIAVIETVFTIPGLGRLMVDSIFARDYPVIQGCLLFVALSYVLVNLVI
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
DLLYPLFDPRVVAE
HHHHHHCCCCCCCC
>Mature Secondary Structure
MLRFILSRLAMAIPTVVLVSVTVFALIRFIPGDPAALMLGDMAQPDQIAAMRVELGLDRS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHCCCCC
MPQQFLIWAGDVLRGDFGRSIVNDEAVLPLVVSRFLVSAEIVVVAVLLASLIAVPAGVIA
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWRQNSLTDLALVGTATVLLSIPTFWLGLLLLLLFGLKLGWLPVLGYVSISDNLVDGLLY
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVLPVVTLVIHEAGVLIRMARASTLEVLRLDYITHARAKGLSEGAVLWRHAFKNAFGPTW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHH
TMIGLILGNLLGGIAVIETVFTIPGLGRLMVDSIFARDYPVIQGCLLFVALSYVLVNLVI
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
DLLYPLFDPRVVAE
HHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9163424; 8796346 [H]