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The map label for this gene is gbh [H]

Identifier: 150397610

GI number: 150397610

Start: 2485757

End: 2486815

Strand: Reverse

Name: gbh [H]

Synonym: Smed_2410

Alternate gene names: 150397610

Gene position: 2486815-2485757 (Counterclockwise)

Preceding gene: 150397613

Following gene: 150397609

Centisome position: 65.76

GC content: 61.57

Gene sequence:

>1059_bases
ATGGCTTGGGATGAACAGAAACTCAACGAACTGAAGGCGAAATATGGCGAAAGCCATGGCGGAGAGCTCTTTGATCCGAC
CTTTCGCAAGGTTGCGGACAAGATCTTCACGAAGAGCGGCACGCGGCTGGCACCCTATTCCGGCATACCGACGTTCCTGA
CCGCTCCCCAGATGCCTGTTGAGGCCGAGAATCCGGATTTCGGAAACCTTCAGGTGGCGATGATCGGCGTTCCCATGGAC
CTCGGCGTCACCAATCGTCCGGGTGCGCGCTTCGGGCCGCGGGCGCTTCGCGCGATCGAGCGCATCGGCCCCTATAACCA
CGTGCTCGGCTGTGCTCCCGTGCATGATCTTCGGGTCGCCGATATCGGTGATGTTCCCTTCCGCAGCCGCTACCGGCTTG
AAATCAGCCACGAGGACATCGAAACGCGGATCCACCAGATCGTCGATGCGGGTGTCGTGCCGCTCTCGGTCGGCGGCGAC
CATTCGATCACGCATCCGATCCTCAAGGCCGTCGGCAGGAAGCAGCCGGTCGGCATGATCCATATCGACGCGCATTGCGA
TACCGGCGGCGCTTTCGATCTCACCAAGTTCCACCACGGCGGCCCGTTCCGCAACGCCGTTCTCGACGGTGTGCTCGATC
CGACCCGCGTCGTCCAGATCGGCATCCGTGGTTCTGCCGAATATCTGTGGGAGTTCTCCTACGAGTCCGGCATGACGGTC
ATTCATGCGGAGGAGGTCGGTGGGCGGGGCATTCCCGCGATCATCGAGAAGGCAAAGAAGATCGTCGGCGATGGCCCGAC
CTATCTTTCCTTCGATATCGACAGCCTTGATCCGAGCTTCGCGCCTGGCACCGGTACGCCCGAAGTCGGGGGCCTGACCA
CCCGTGAGGTCCTGGAGTTGATCCGTGGGCTGAAGGGCGTCAATCTCGTCGGTGGCGATGTCGTCGAAGTGGCGCCGCAA
TACGACGCGACCACCAATACCGCTCACGCCGGCGCCCAGGTGCTCTTCGAGATACTGAGCCTGATGGTCTTCAGTCCGTC
CGTTACAGCCAAAGGCTGA

Upstream 100 bases:

>100_bases
GGGGAACCTGATCGCGCCGCTTCGGATCGGCAATGCGCAAGACTTGGCTTGCGGAGCATCATGTGCGAGCCCCCGGCCGA
ACGAAACGGAGGTCCGCCGC

Downstream 100 bases:

>100_bases
TGCATTGAAGAATGATCCGGTGCCGTTGCTCGTGGCGGGCAGGGGCGGATCACGGTAATCTGAAGGACGACGGTTGACAT
TCCGCTGATGCGCGGCGGGG

Product: putative agmatinase

Products: NA

Alternate protein names: GBase; D-arginase [H]

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MAWDEQKLNELKAKYGESHGGELFDPTFRKVADKIFTKSGTRLAPYSGIPTFLTAPQMPVEAENPDFGNLQVAMIGVPMD
LGVTNRPGARFGPRALRAIERIGPYNHVLGCAPVHDLRVADIGDVPFRSRYRLEISHEDIETRIHQIVDAGVVPLSVGGD
HSITHPILKAVGRKQPVGMIHIDAHCDTGGAFDLTKFHHGGPFRNAVLDGVLDPTRVVQIGIRGSAEYLWEFSYESGMTV
IHAEEVGGRGIPAIIEKAKKIVGDGPTYLSFDIDSLDPSFAPGTGTPEVGGLTTREVLELIRGLKGVNLVGGDVVEVAPQ
YDATTNTAHAGAQVLFEILSLMVFSPSVTAKG

Sequences:

>Translated_352_residues
MAWDEQKLNELKAKYGESHGGELFDPTFRKVADKIFTKSGTRLAPYSGIPTFLTAPQMPVEAENPDFGNLQVAMIGVPMD
LGVTNRPGARFGPRALRAIERIGPYNHVLGCAPVHDLRVADIGDVPFRSRYRLEISHEDIETRIHQIVDAGVVPLSVGGD
HSITHPILKAVGRKQPVGMIHIDAHCDTGGAFDLTKFHHGGPFRNAVLDGVLDPTRVVQIGIRGSAEYLWEFSYESGMTV
IHAEEVGGRGIPAIIEKAKKIVGDGPTYLSFDIDSLDPSFAPGTGTPEVGGLTTREVLELIRGLKGVNLVGGDVVEVAPQ
YDATTNTAHAGAQVLFEILSLMVFSPSVTAKG
>Mature_351_residues
AWDEQKLNELKAKYGESHGGELFDPTFRKVADKIFTKSGTRLAPYSGIPTFLTAPQMPVEAENPDFGNLQVAMIGVPMDL
GVTNRPGARFGPRALRAIERIGPYNHVLGCAPVHDLRVADIGDVPFRSRYRLEISHEDIETRIHQIVDAGVVPLSVGGDH
SITHPILKAVGRKQPVGMIHIDAHCDTGGAFDLTKFHHGGPFRNAVLDGVLDPTRVVQIGIRGSAEYLWEFSYESGMTVI
HAEEVGGRGIPAIIEKAKKIVGDGPTYLSFDIDSLDPSFAPGTGTPEVGGLTTREVLELIRGLKGVNLVGGDVVEVAPQY
DATTNTAHAGAQVLFEILSLMVFSPSVTAKG

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=284, Percent_Identity=46.830985915493, Blast_Score=251, Evalue=6e-67,
Organism=Homo sapiens, GI10947139, Length=300, Percent_Identity=29.3333333333333, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4502215, Length=308, Percent_Identity=25, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI1789306, Length=255, Percent_Identity=41.1764705882353, Blast_Score=182, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI71996843, Length=219, Percent_Identity=29.2237442922374, Blast_Score=71, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6325146, Length=222, Percent_Identity=32.4324324324324, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.7; =3.5.3.10 [H]

Molecular weight: Translated: 37875; Mature: 37743

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWDEQKLNELKAKYGESHGGELFDPTFRKVADKIFTKSGTRLAPYSGIPTFLTAPQMPV
CCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEECCCCCCCHHHCCCCCCC
EAENPDFGNLQVAMIGVPMDLGVTNRPGARFGPRALRAIERIGPYNHVLGCAPVHDLRVA
CCCCCCCCCEEEEEEECCEECCCCCCCCCCCCHHHHHHHHHHCCHHHHEECCCCCCEEEE
DIGDVPFRSRYRLEISHEDIETRIHQIVDAGVVPLSVGGDHSITHPILKAVGRKQPVGMI
CCCCCCCCCEEEEEECHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCCCCCEE
HIDAHCDTGGAFDLTKFHHGGPFRNAVLDGVLDPTRVVQIGIRGSAEYLWEFSYESGMTV
EEEEECCCCCCEEEHHCCCCCCHHHHHHHHCCCCCCEEEEECCCCCEEEEEEECCCCCEE
IHAEEVGGRGIPAIIEKAKKIVGDGPTYLSFDIDSLDPSFAPGTGTPEVGGLTTREVLEL
EEECCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHH
IRGLKGVNLVGGDVVEVAPQYDATTNTAHAGAQVLFEILSLMVFSPSVTAKG
HHCCCCCEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
AWDEQKLNELKAKYGESHGGELFDPTFRKVADKIFTKSGTRLAPYSGIPTFLTAPQMPV
CCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEECCCCCCCHHHCCCCCCC
EAENPDFGNLQVAMIGVPMDLGVTNRPGARFGPRALRAIERIGPYNHVLGCAPVHDLRVA
CCCCCCCCCEEEEEEECCEECCCCCCCCCCCCHHHHHHHHHHCCHHHHEECCCCCCEEEE
DIGDVPFRSRYRLEISHEDIETRIHQIVDAGVVPLSVGGDHSITHPILKAVGRKQPVGMI
CCCCCCCCCEEEEEECHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCCCCCEE
HIDAHCDTGGAFDLTKFHHGGPFRNAVLDGVLDPTRVVQIGIRGSAEYLWEFSYESGMTV
EEEEECCCCCCEEEHHCCCCCCHHHHHHHHCCCCCCEEEEECCCCCEEEEEEECCCCCEE
IHAEEVGGRGIPAIIEKAKKIVGDGPTYLSFDIDSLDPSFAPGTGTPEVGGLTTREVLEL
EEECCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHH
IRGLKGVNLVGGDVVEVAPQYDATTNTAHAGAQVLFEILSLMVFSPSVTAKG
HHCCCCCEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA