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The map label for this gene is ureD

Identifier: 150397589

GI number: 150397589

Start: 2464905

End: 2465738

Strand: Reverse

Name: ureD

Synonym: Smed_2389

Alternate gene names: 150397589

Gene position: 2465738-2464905 (Counterclockwise)

Preceding gene: 150397590

Following gene: 150397588

Centisome position: 65.2

GC content: 64.15

Gene sequence:

>834_bases
ATGGAAGCGGCAGCGGCGATTGCCCCTCAGCGGGCATGGGGAAAAGGACGGCTCGTCGCCAAGACCGGAGGGGCGCGCAC
GCGCATCGCCGGTCTCTATCAGGAAGGTTGCGCCAAGATCCGCTTGCCAAGGACCTTCGACGCATCGATGGAGGCCGTGC
TCATCAATTCGTCGGGCGGCGTGACCGGTGGCGACCGGCTCGCTTGGGAGTTCGAGGCGGGCGAGGGCACCAACCTCACG
CTGACGACACAGGCCTGCGAGAAGGTTTACAAGGCGAGTGTGGACACGGCCGTGGTTGCGACGCGCATTTCGGTCGCTGC
CCGCGGCCACGTCGACTGGCTGCCGCAGGAGTCAATCCTGTTTGATCGGTCGGCCCTGTCACGCTCTTTGGAGGTCGATC
TCGCTCCTGATGCGTCCTTTCTTGCGCTGGAGGCGGTTCTGATCGGCCGGAAGGCCATGGGAGAGACGGTGCGGTCCGGC
CTCTTCCGCGATCATTGGCGCATTCGCAGCGGTGGAGCGCTGGTCCACGCGGAAAATCTTGCATTAGCCGGCGATATCGC
GGCGCTAGGGTCGCGGCGAGCCGTGCTCGACGGCGCGGTCGCCTTTGCAACCCTCGTCTATGTCGCCCCTGATTGCGAGG
CCCTGCTCCCGAGATTGCGGACATCGCTTGCGGAACATGCCCTCTCGGGCGTCAGCCATTTTGCCGTTAACGGGCGCGAC
AAGATCGTCGCCCGCGTGGTTGCGGCCGACGGGTTCGCGCTCAGAAAAATTCTGATCCCACTGATTTCGCACTTGCGTAA
AGGCGCATCTGTGCCGAGAGTCTGGACTCTCTGA

Upstream 100 bases:

>100_bases
TTCGGGTGCGTTGGCCGACCTCATGAAAGCTACGATTTGACTTTGCCCTTGTGGTTTCGGACGATAGTCGTATCGGCAGG
AACACTTCGGCGAAGATCTG

Downstream 100 bases:

>100_bases
ATCCGCGAACAATTGGATGGCGACGCATGAATCTCACCCCGCGCGAAAAGGATAAGCTGCTGATTTCAATGGCGGCGATG
GTCGCGCGCCGGCGGCTCGA

Product: urease accessory protein UreD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MEAAAAIAPQRAWGKGRLVAKTGGARTRIAGLYQEGCAKIRLPRTFDASMEAVLINSSGGVTGGDRLAWEFEAGEGTNLT
LTTQACEKVYKASVDTAVVATRISVAARGHVDWLPQESILFDRSALSRSLEVDLAPDASFLALEAVLIGRKAMGETVRSG
LFRDHWRIRSGGALVHAENLALAGDIAALGSRRAVLDGAVAFATLVYVAPDCEALLPRLRTSLAEHALSGVSHFAVNGRD
KIVARVVAADGFALRKILIPLISHLRKGASVPRVWTL

Sequences:

>Translated_277_residues
MEAAAAIAPQRAWGKGRLVAKTGGARTRIAGLYQEGCAKIRLPRTFDASMEAVLINSSGGVTGGDRLAWEFEAGEGTNLT
LTTQACEKVYKASVDTAVVATRISVAARGHVDWLPQESILFDRSALSRSLEVDLAPDASFLALEAVLIGRKAMGETVRSG
LFRDHWRIRSGGALVHAENLALAGDIAALGSRRAVLDGAVAFATLVYVAPDCEALLPRLRTSLAEHALSGVSHFAVNGRD
KIVARVVAADGFALRKILIPLISHLRKGASVPRVWTL
>Mature_277_residues
MEAAAAIAPQRAWGKGRLVAKTGGARTRIAGLYQEGCAKIRLPRTFDASMEAVLINSSGGVTGGDRLAWEFEAGEGTNLT
LTTQACEKVYKASVDTAVVATRISVAARGHVDWLPQESILFDRSALSRSLEVDLAPDASFLALEAVLIGRKAMGETVRSG
LFRDHWRIRSGGALVHAENLALAGDIAALGSRRAVLDGAVAFATLVYVAPDCEALLPRLRTSLAEHALSGVSHFAVNGRD
KIVARVVAADGFALRKILIPLISHLRKGASVPRVWTL

Specific function: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter

COG id: COG0829

COG function: function code O; Urease accessory protein UreH

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ureD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): URED_SINMW (A6UC41)

Other databases:

- EMBL:   CP000738
- RefSeq:   YP_001328056.1
- STRING:   A6UC41
- GeneID:   5323250
- GenomeReviews:   CP000738_GR
- KEGG:   smd:Smed_2389
- eggNOG:   COG0829
- HOGENOM:   HBG711156
- OMA:   QETILFD
- ProtClustDB:   CLSK2484748
- BioCyc:   SMED366394:SMED_2389-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01384
- InterPro:   IPR002669

Pfam domain/function: PF01774 UreD

EC number: NA

Molecular weight: Translated: 29400; Mature: 29400

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAAAAIAPQRAWGKGRLVAKTGGARTRIAGLYQEGCAKIRLPRTFDASMEAVLINSSGG
CCCCHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCEEECCCCCCCCCEEEEEECCCC
VTGGDRLAWEFEAGEGTNLTLTTQACEKVYKASVDTAVVATRISVAARGHVDWLPQESIL
CCCCCCEEEEEECCCCCEEEEEHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHH
FDRSALSRSLEVDLAPDASFLALEAVLIGRKAMGETVRSGLFRDHWRIRSGGALVHAENL
HHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCEEEEECCE
ALAGDIAALGSRRAVLDGAVAFATLVYVAPDCEALLPRLRTSLAEHALSGVSHFAVNGRD
EEECHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCH
KIVARVVAADGFALRKILIPLISHLRKGASVPRVWTL
HEEHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEECC
>Mature Secondary Structure
MEAAAAIAPQRAWGKGRLVAKTGGARTRIAGLYQEGCAKIRLPRTFDASMEAVLINSSGG
CCCCHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCEEECCCCCCCCCEEEEEECCCC
VTGGDRLAWEFEAGEGTNLTLTTQACEKVYKASVDTAVVATRISVAARGHVDWLPQESIL
CCCCCCEEEEEECCCCCEEEEEHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHH
FDRSALSRSLEVDLAPDASFLALEAVLIGRKAMGETVRSGLFRDHWRIRSGGALVHAENL
HHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCEEEEECCE
ALAGDIAALGSRRAVLDGAVAFATLVYVAPDCEALLPRLRTSLAEHALSGVSHFAVNGRD
EEECHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCH
KIVARVVAADGFALRKILIPLISHLRKGASVPRVWTL
HEEHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA