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The map label for this gene is crp [C]

Identifier: 150397576

GI number: 150397576

Start: 2456829

End: 2457509

Strand: Direct

Name: crp [C]

Synonym: Smed_2376

Alternate gene names: 150397576

Gene position: 2456829-2457509 (Clockwise)

Preceding gene: 150397575

Following gene: 150397591

Centisome position: 64.96

GC content: 63.44

Gene sequence:

>681_bases
ATGAAGACCTCGCGACTGACTTCGAACGACAGGGCCGTGCTTCTCGGTTCGCGTCTTTTCGCAAACCTGCCGGCACCCGC
CGCCGAAGCTGTTCTTGAAGGCGCCACCATTTCAAGACACGAGGCGCAGGATGTTCTTTTCCATCAGGGCGACGCCATCG
AGCACGTCTTCTTCGTCGTCTCCGGCCTCGTGCGTCTCTACGGCACCGGCAAGGGCGGGCGCGAGGCGGACATCGCCGTG
TTTCCCAGGGGCGCGCTTTTCGGCGAAAAGGCCGTCTTCCTTGATCAGCGCGCAACCGCACACGCGCAAGCCGTGCACCC
GTCCATTATCGCGAAGCTGGACGGCCCGAGGCTTTGCCGGCTTGTCCGCGAAGAGGCCGATGTGGCGTGGGCGCTCCTAG
AACTCCTCTGCCGTCATGGGCAGATGACGGAAAAGCGCCTTGCCGAGGATCGATTGCTGACCGCACCGCAGCGTGTCGCA
AACTACATCCTCGGCCAGTGCCCGGGCGACTCACCGGCCTTCACCTTCCGGCTTCCATTTCAAAAGAATGTGCTGGCAGG
CAAGCTCGGGCTTGCGCCGGAGGCGCTCTCGCGCGCCTTCTCGACCCTGCGGCAGTCGGGCGTCATCGTGAAGGGCCGCC
TGATCGAAATCCGCGATAGAGAGGCACTGGAGCGATTCTGA

Upstream 100 bases:

>100_bases
TCCTGGAGCGCGGGCTTTCTCCATGAGCTTTTGACCAAGGTCAACTCACCACCTGTCCGGAAGTCGTAGCGTCACCTCGA
CTTTATTGGGGATGGCTGGA

Downstream 100 bases:

>100_bases
CCGAGGCGGCTTAGAGACCACCATGCAGTATCAGGAAATCGACGATCCGCTCCACCCCATCGCCCCGTTTCATGTCGGAA
AACACGAAGGGCTTCTCGCC

Product: CRP/FNR family transcriptional regulator

Products: NA

Alternate protein names: Crp/FNR Family Transcriptional Regulator; Transcriptional Activator FtrB; Transcriptional Regulator; Crp/Fnr Family Transcriptional Regulator; Crp Family Transcriptional Regulator; CRP/FNR Family Transcriptional Regulator; Regulator Of Biofilm Formation Fnr Family; Transcription Regulator; CRP/FNR-Like Transcriptional Regulator; Transcriptional Regulator DnrS; CRP Family Transcriptional Regulator; Transcriptional Activator; DnrE Protein; CAMP-Dependent Transcriptional Regulator; DNR Protein; Transcription Regulator Protein; Transcriptional Regulator Dnr-Type; FNR-Like Transcriptional Regulator; CAMP-Bindin Transcriptional Regulator; Transcriptional Regulator CAP/Crp Family; Transcriptional Regulator Dnr; Transcriptional Regulator Dnr/Nnr Type; Transcriptional Regulator Protein Fnr/CRP Family

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MKTSRLTSNDRAVLLGSRLFANLPAPAAEAVLEGATISRHEAQDVLFHQGDAIEHVFFVVSGLVRLYGTGKGGREADIAV
FPRGALFGEKAVFLDQRATAHAQAVHPSIIAKLDGPRLCRLVREEADVAWALLELLCRHGQMTEKRLAEDRLLTAPQRVA
NYILGQCPGDSPAFTFRLPFQKNVLAGKLGLAPEALSRAFSTLRQSGVIVKGRLIEIRDREALERF

Sequences:

>Translated_226_residues
MKTSRLTSNDRAVLLGSRLFANLPAPAAEAVLEGATISRHEAQDVLFHQGDAIEHVFFVVSGLVRLYGTGKGGREADIAV
FPRGALFGEKAVFLDQRATAHAQAVHPSIIAKLDGPRLCRLVREEADVAWALLELLCRHGQMTEKRLAEDRLLTAPQRVA
NYILGQCPGDSPAFTFRLPFQKNVLAGKLGLAPEALSRAFSTLRQSGVIVKGRLIEIRDREALERF
>Mature_226_residues
MKTSRLTSNDRAVLLGSRLFANLPAPAAEAVLEGATISRHEAQDVLFHQGDAIEHVFFVVSGLVRLYGTGKGGREADIAV
FPRGALFGEKAVFLDQRATAHAQAVHPSIIAKLDGPRLCRLVREEADVAWALLELLCRHGQMTEKRLAEDRLLTAPQRVA
NYILGQCPGDSPAFTFRLPFQKNVLAGKLGLAPEALSRAFSTLRQSGVIVKGRLIEIRDREALERF

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 24761; Mature: 24761

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTSRLTSNDRAVLLGSRLFANLPAPAAEAVLEGATISRHEAQDVLFHQGDAIEHVFFVV
CCCCCCCCCCCEEEEEHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHH
SGLVRLYGTGKGGREADIAVFPRGALFGEKAVFLDQRATAHAQAVHPSIIAKLDGPRLCR
HHHHHHHCCCCCCCCCCEEEECCCCCCCCCCEEECCHHHHHHHHHCHHHHEECCCHHHHH
LVREEADVAWALLELLCRHGQMTEKRLAEDRLLTAPQRVANYILGQCPGDSPAFTFRLPF
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEECCC
QKNVLAGKLGLAPEALSRAFSTLRQSGVIVKGRLIEIRDREALERF
CCCHHHCCCCCCHHHHHHHHHHHHHCCEEEEEEEEEECCHHHHHCC
>Mature Secondary Structure
MKTSRLTSNDRAVLLGSRLFANLPAPAAEAVLEGATISRHEAQDVLFHQGDAIEHVFFVV
CCCCCCCCCCCEEEEEHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHH
SGLVRLYGTGKGGREADIAVFPRGALFGEKAVFLDQRATAHAQAVHPSIIAKLDGPRLCR
HHHHHHHCCCCCCCCCCEEEECCCCCCCCCCEEECCHHHHHHHHHCHHHHEECCCHHHHH
LVREEADVAWALLELLCRHGQMTEKRLAEDRLLTAPQRVANYILGQCPGDSPAFTFRLPF
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEECCC
QKNVLAGKLGLAPEALSRAFSTLRQSGVIVKGRLIEIRDREALERF
CCCHHHCCCCCCHHHHHHHHHHHHHCCEEEEEEEEEECCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA