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The map label for this gene is yhcS [C]

Identifier: 150397563

GI number: 150397563

Start: 2440249

End: 2441148

Strand: Direct

Name: yhcS [C]

Synonym: Smed_2363

Alternate gene names: 150397563

Gene position: 2440249-2441148 (Clockwise)

Preceding gene: 150397561

Following gene: 150397564

Centisome position: 64.52

GC content: 63.56

Gene sequence:

>900_bases
ATGGAACGCTTCACAGGCATTTCGGTCTTCGTCGAGGTCGCCGACGCCGGCGGCTTTTCCGCTGCCGCCGCGCGACTCAA
TCTTACGCGGTCGGCCGTGGGCAAGACGGTTTCCAGGCTCGAACAGAGGCTCGGTGTGCGTCTTTTTAATCGCACCACAC
GGACTCAGAACCTCACTGAAGAAGGGCAGCTTTTCTACGAGAGCTGCCAGAAGGCGCTCGGTGAAATAAAAACGGCCGAG
AGCCTCCTCGAGTCCGGGAGGCGCGAAATACGCGGTCGTCTTCGCATCTCGATGCCGGTCCTCTTCGGACGCCAATGCGT
GGCGCCATTGCTTCGCGACCTGCTGCAGGCGCATCCGCATCTGGAGTTCGATCTCTCCTTCAACGACCGCGTCATCGACC
TCCTCGACGAAGGTTTCGATCTCGCCGTCCGCAACGCCCCGCTCGGCAACGGCGCCGGCCTCATGATGCGCACGGTCGCG
GAACAGCGCATGACGGTCTGCGCCTCGCCGGCCTATCTCGAAGCGCGCGGCATGCCAAAAAAGGTGGCGGAACTCGCCGC
ACATGAGGGGGTCGTCTATTGCCGCGGAGGCGAACCGCGATCCTGGACCTTTCCCGCCGAGGGGAAGGCGGCGGAAGCCG
TATTGCCGCAGGCACGGCTGAGACTCGACGATCTCGCAGCAATCGCCGATGCCGCCGCTGCGGGCTTCGGCCTTGCATGG
CTGCCTTGCTGGCTCGTGCGCGAGCGCGTGCAGAAAGGCGAGCTCGTCCGCGTGCTGACCGACCGGCCCGGATTGATTTT
CAAGGCCCATGCAGTCTGGCCGCAAACGCAACACGTCCTGCCTAAACTGCGGGTGGTGATCGATAAACTGGCCAATGCGC
TGCCGCGCATCATGGAGTAG

Upstream 100 bases:

>100_bases
GTTCCTTTCCATCTGTTTCGGTCGGGCGAGCATAGTGTTGAATTTGCCTCTCCAGTTGCGGTATGATTTCCCATCATTGG
TTCCTCAAAGGACGCAATCC

Downstream 100 bases:

>100_bases
GTCCCTGCATGGGCATGTGCATGTGCAGCGCGTTCCGCACAAGTCACGGAAACGAAACAGTTTGTACAAAAAACGTAAGT
TGCCGGCACCAGTGATCTGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MERFTGISVFVEVADAGGFSAAAARLNLTRSAVGKTVSRLEQRLGVRLFNRTTRTQNLTEEGQLFYESCQKALGEIKTAE
SLLESGRREIRGRLRISMPVLFGRQCVAPLLRDLLQAHPHLEFDLSFNDRVIDLLDEGFDLAVRNAPLGNGAGLMMRTVA
EQRMTVCASPAYLEARGMPKKVAELAAHEGVVYCRGGEPRSWTFPAEGKAAEAVLPQARLRLDDLAAIADAAAAGFGLAW
LPCWLVRERVQKGELVRVLTDRPGLIFKAHAVWPQTQHVLPKLRVVIDKLANALPRIME

Sequences:

>Translated_299_residues
MERFTGISVFVEVADAGGFSAAAARLNLTRSAVGKTVSRLEQRLGVRLFNRTTRTQNLTEEGQLFYESCQKALGEIKTAE
SLLESGRREIRGRLRISMPVLFGRQCVAPLLRDLLQAHPHLEFDLSFNDRVIDLLDEGFDLAVRNAPLGNGAGLMMRTVA
EQRMTVCASPAYLEARGMPKKVAELAAHEGVVYCRGGEPRSWTFPAEGKAAEAVLPQARLRLDDLAAIADAAAAGFGLAW
LPCWLVRERVQKGELVRVLTDRPGLIFKAHAVWPQTQHVLPKLRVVIDKLANALPRIME
>Mature_299_residues
MERFTGISVFVEVADAGGFSAAAARLNLTRSAVGKTVSRLEQRLGVRLFNRTTRTQNLTEEGQLFYESCQKALGEIKTAE
SLLESGRREIRGRLRISMPVLFGRQCVAPLLRDLLQAHPHLEFDLSFNDRVIDLLDEGFDLAVRNAPLGNGAGLMMRTVA
EQRMTVCASPAYLEARGMPKKVAELAAHEGVVYCRGGEPRSWTFPAEGKAAEAVLPQARLRLDDLAAIADAAAAGFGLAW
LPCWLVRERVQKGELVRVLTDRPGLIFKAHAVWPQTQHVLPKLRVVIDKLANALPRIME

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=292, Percent_Identity=30.1369863013699, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI145693193, Length=301, Percent_Identity=28.2392026578073, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1787589, Length=295, Percent_Identity=29.4915254237288, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1787128, Length=289, Percent_Identity=30.1038062283737, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1786401, Length=287, Percent_Identity=28.2229965156794, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI87081978, Length=260, Percent_Identity=32.6923076923077, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1789440, Length=288, Percent_Identity=28.4722222222222, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI157672245, Length=148, Percent_Identity=29.7297297297297, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1786448, Length=288, Percent_Identity=26.3888888888889, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789173, Length=259, Percent_Identity=26.6409266409266, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788706, Length=268, Percent_Identity=25.3731343283582, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788481, Length=287, Percent_Identity=25.7839721254355, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786508, Length=255, Percent_Identity=25.8823529411765, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786713, Length=139, Percent_Identity=32.3741007194245, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787601, Length=131, Percent_Identity=25.9541984732824, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32992; Mature: 32992

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERFTGISVFVEVADAGGFSAAAARLNLTRSAVGKTVSRLEQRLGVRLFNRTTRTQNLTE
CCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
EGQLFYESCQKALGEIKTAESLLESGRREIRGRLRISMPVLFGRQCVAPLLRDLLQAHPH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHHHCCC
LEFDLSFNDRVIDLLDEGFDLAVRNAPLGNGAGLMMRTVAEQRMTVCASPAYLEARGMPK
EEEEECCCCHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCHH
KVAELAAHEGVVYCRGGEPRSWTFPAEGKAAEAVLPQARLRLDDLAAIADAAAAGFGLAW
HHHHHHHHCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LPCWLVRERVQKGELVRVLTDRPGLIFKAHAVWPQTQHVLPKLRVVIDKLANALPRIME
HHHHHHHHHHHCCCEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MERFTGISVFVEVADAGGFSAAAARLNLTRSAVGKTVSRLEQRLGVRLFNRTTRTQNLTE
CCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
EGQLFYESCQKALGEIKTAESLLESGRREIRGRLRISMPVLFGRQCVAPLLRDLLQAHPH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHHHCCC
LEFDLSFNDRVIDLLDEGFDLAVRNAPLGNGAGLMMRTVAEQRMTVCASPAYLEARGMPK
EEEEECCCCHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCHH
KVAELAAHEGVVYCRGGEPRSWTFPAEGKAAEAVLPQARLRLDDLAAIADAAAAGFGLAW
HHHHHHHHCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LPCWLVRERVQKGELVRVLTDRPGLIFKAHAVWPQTQHVLPKLRVVIDKLANALPRIME
HHHHHHHHHHHCCCEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]