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The map label for this gene is cyaA [H]

Identifier: 150397564

GI number: 150397564

Start: 2441307

End: 2442983

Strand: Direct

Name: cyaA [H]

Synonym: Smed_2364

Alternate gene names: 150397564

Gene position: 2441307-2442983 (Clockwise)

Preceding gene: 150397563

Following gene: 150397566

Centisome position: 64.55

GC content: 63.98

Gene sequence:

>1677_bases
TTGACGATACTCTCCGCCAGCACGCGCAAGAAGATGCACCTGATCTCCGGGGCTGTGCTCGGCATATTCGTGCTCTGTCA
CTTCTCAAATCATGCGCTTGGACTCGTCTCGATCGGCGCGATGGAAGTGGGGCGGCGGATTTTTACCTCAGTCTGGCACA
GCGTACCGGGTACCGTCGTGCTTTACGGAGCGCTGCTCCTGCATTTCCTTATGGCGCTCGACAGCCTCTATAGGCGGCAG
ACATTCAGAATGCCTGCCGGAGAAGCCCTGAAGATCGTCTTTGGCCTGAGCCTGCCGTTTCTGCTCGTCCCTCACGTGGT
CGCCACCCGCGTGGAGCCGCTCCTTACGGGCATTTACCCGGATTATGCTGGAATTCTGCGAACCCTGTGGTCAAGCTCGA
TCAACGCCTCCCGGCAGTCGCTGGCGCTGATCGTCGTCTGGGGCCATGCCTGTCTTGGCGCCTGGTTCTGGATGCGCGGC
CGCGCATGGTTTCCGCGATATGAGACCCTGCTCTATACCGTCGCGCTTCTGGTGCCGATCTTTGCGCTTCTCGGCTTCGT
GAACGGCGCGCGTTCGCTCGAGCGGGACTATGCCGAACATGGAGGTTACGGCGACCGTGCCTATGCCGGCGCGTCGCAGG
AAAGGGCCGATCCCGCTGTGCTCGAAAGCATCCGGCTCGCATTTTACGGCGGCTTCGCAGCCCTCATCGGCGCAACGCTC
GCGCTGCGCGCCATGCCTGCGCGTGGCCGCATCCGCATCCGTTATCCGGACGGGCGGGTCGCTGCCGTCAGCCTCGGCTT
CAGCGTGCTCGAGGCGAGCCGGGCAGCCGGCATTCCGCATGTTTCGGTCTGCGGCGGACGCGGCCGCTGCTCGACCTGCC
GCGTCCGGATCACCCAGGGGCTCGAGAATCAGCCCGCACCTGAAGCAGCGGAGCTCGCGACGCTGACCCGCATCGGCGCG
CCCGAAAACATACGCCTCGCCTGTCAGTTCCGGCCCGTTCACAATGTGAGCGTCGTACCGATCCTCAATACCGATAGTAT
TGGGGTCAAGACGCAGATCGCCCGCCAGAATGCCGGCGGCCGCGAGCGCCGCGTGGCGGTGCTCTTTTGCGACCTGCGCG
ACTTCACCCGAATTGCCGAGCACAGGCTGCCCTACGACACCGTCTTCCTGCTCAACCGCTACTTCGAAGTCGTCGGCGAA
GCCGTCGAAGGTTCGGGCGGCGTAATCGACAAGTTCATCGGCGACGGGGCACTCGCGATCTTTGGTCTGAAGACCCCCTT
GCCGGAAGCCTGCCGGCAGGCACTTTCGGCCGCTGCCCGATTGTCGCAGGGCATCCGCGCGCTGAACCAGACATTCGAAG
GGGAGCTCGACCAGCCACTGAGGCTCGCCATCGGCCTGCATGCGGGCCCGGCGATCATCGGCGAAATGGGATACGGTCAG
GCAACGTCGCTCACCGCCGTCGGCGACACCATCAACACCGCGAGCCGCCTGGAAGGCCTTGCAAAAGAGCACGACGCCGA
GCTTGCGGTTTCCGCCGAACTGGTCCAGCGCGCCGGTCTTGCCTTTGAAGGCCATAGACGCCTAGAAATCAGTCTGCGCG
GCCGCCAGGCGACGCTGGAAACCTGGATAGTGGGTGACGCGTCACAGCTCTCGCTTTCGCTACCGTCACCGAGCTGA

Upstream 100 bases:

>100_bases
AGTTTGTACAAAAAACGTAAGTTGCCGGCACCAGTGATCTGGTTGATAAGGAAGATACCGAAGCGGGCCGCTCCGCGGTC
GCCAGAGCCAGGCAAATTAT

Downstream 100 bases:

>100_bases
CCGGCCTCTCATCCGCCTGCCGGCACCTTCTCGCCGCAAGCGGGGCAAAGGGATATGCCGCGCCGTCCAACTCCCTCTAC
AGAGATGAAGGCCGTCCGCG

Product: putative adenylate/guanylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 1; Adenylyl cyclase 1; AC 1 [H]

Number of amino acids: Translated: 558; Mature: 557

Protein sequence:

>558_residues
MTILSASTRKKMHLISGAVLGIFVLCHFSNHALGLVSIGAMEVGRRIFTSVWHSVPGTVVLYGALLLHFLMALDSLYRRQ
TFRMPAGEALKIVFGLSLPFLLVPHVVATRVEPLLTGIYPDYAGILRTLWSSSINASRQSLALIVVWGHACLGAWFWMRG
RAWFPRYETLLYTVALLVPIFALLGFVNGARSLERDYAEHGGYGDRAYAGASQERADPAVLESIRLAFYGGFAALIGATL
ALRAMPARGRIRIRYPDGRVAAVSLGFSVLEASRAAGIPHVSVCGGRGRCSTCRVRITQGLENQPAPEAAELATLTRIGA
PENIRLACQFRPVHNVSVVPILNTDSIGVKTQIARQNAGGRERRVAVLFCDLRDFTRIAEHRLPYDTVFLLNRYFEVVGE
AVEGSGGVIDKFIGDGALAIFGLKTPLPEACRQALSAAARLSQGIRALNQTFEGELDQPLRLAIGLHAGPAIIGEMGYGQ
ATSLTAVGDTINTASRLEGLAKEHDAELAVSAELVQRAGLAFEGHRRLEISLRGRQATLETWIVGDASQLSLSLPSPS

Sequences:

>Translated_558_residues
MTILSASTRKKMHLISGAVLGIFVLCHFSNHALGLVSIGAMEVGRRIFTSVWHSVPGTVVLYGALLLHFLMALDSLYRRQ
TFRMPAGEALKIVFGLSLPFLLVPHVVATRVEPLLTGIYPDYAGILRTLWSSSINASRQSLALIVVWGHACLGAWFWMRG
RAWFPRYETLLYTVALLVPIFALLGFVNGARSLERDYAEHGGYGDRAYAGASQERADPAVLESIRLAFYGGFAALIGATL
ALRAMPARGRIRIRYPDGRVAAVSLGFSVLEASRAAGIPHVSVCGGRGRCSTCRVRITQGLENQPAPEAAELATLTRIGA
PENIRLACQFRPVHNVSVVPILNTDSIGVKTQIARQNAGGRERRVAVLFCDLRDFTRIAEHRLPYDTVFLLNRYFEVVGE
AVEGSGGVIDKFIGDGALAIFGLKTPLPEACRQALSAAARLSQGIRALNQTFEGELDQPLRLAIGLHAGPAIIGEMGYGQ
ATSLTAVGDTINTASRLEGLAKEHDAELAVSAELVQRAGLAFEGHRRLEISLRGRQATLETWIVGDASQLSLSLPSPS
>Mature_557_residues
TILSASTRKKMHLISGAVLGIFVLCHFSNHALGLVSIGAMEVGRRIFTSVWHSVPGTVVLYGALLLHFLMALDSLYRRQT
FRMPAGEALKIVFGLSLPFLLVPHVVATRVEPLLTGIYPDYAGILRTLWSSSINASRQSLALIVVWGHACLGAWFWMRGR
AWFPRYETLLYTVALLVPIFALLGFVNGARSLERDYAEHGGYGDRAYAGASQERADPAVLESIRLAFYGGFAALIGATLA
LRAMPARGRIRIRYPDGRVAAVSLGFSVLEASRAAGIPHVSVCGGRGRCSTCRVRITQGLENQPAPEAAELATLTRIGAP
ENIRLACQFRPVHNVSVVPILNTDSIGVKTQIARQNAGGRERRVAVLFCDLRDFTRIAEHRLPYDTVFLLNRYFEVVGEA
VEGSGGVIDKFIGDGALAIFGLKTPLPEACRQALSAAARLSQGIRALNQTFEGELDQPLRLAIGLHAGPAIIGEMGYGQA
TSLTAVGDTINTASRLEGLAKEHDAELAVSAELVQRAGLAFEGHRRLEISLRGRQATLETWIVGDASQLSLSLPSPS

Specific function: Unknown

COG id: COG0633

COG function: function code C; Ferredoxin

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 guanylate cyclase domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI17534655, Length=195, Percent_Identity=30.2564102564103, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI161078020, Length=196, Percent_Identity=30.1020408163265, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054 [H]

Pfam domain/function: PF00211 Guanylate_cyc [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 60299; Mature: 60167

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS50125 GUANYLATE_CYCLASES_2 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTILSASTRKKMHLISGAVLGIFVLCHFSNHALGLVSIGAMEVGRRIFTSVWHSVPGTVV
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCHHH
LYGALLLHFLMALDSLYRRQTFRMPAGEALKIVFGLSLPFLLVPHVVATRVEPLLTGIYP
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC
DYAGILRTLWSSSINASRQSLALIVVWGHACLGAWFWMRGRAWFPRYETLLYTVALLVPI
HHHHHHHHHHHCCCCCCCCCEEEEEEECHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
FALLGFVNGARSLERDYAEHGGYGDRAYAGASQERADPAVLESIRLAFYGGFAALIGATL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ALRAMPARGRIRIRYPDGRVAAVSLGFSVLEASRAAGIPHVSVCGGRGRCSTCRVRITQG
HHHCCCCCCEEEEECCCCCEEEEEHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEEECC
LENQPAPEAAELATLTRIGAPENIRLACQFRPVHNVSVVPILNTDSIGVKTQIARQNAGG
CCCCCCCCHHHHHHHHHCCCCCCEEEEEEEECCCCEEEEEEECCCCCCCCHHHHHCCCCC
RERRVAVLFCDLRDFTRIAEHRLPYDTVFLLNRYFEVVGEAVEGSGGVIDKFIGDGALAI
CCCEEEEEEECHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCEEEE
FGLKTPLPEACRQALSAAARLSQGIRALNQTFEGELDQPLRLAIGLHAGPAIIGEMGYGQ
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHEECCCCCC
ATSLTAVGDTINTASRLEGLAKEHDAELAVSAELVQRAGLAFEGHRRLEISLRGRQATLE
CCEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEECCCEEEEEEECCCEEEEE
TWIVGDASQLSLSLPSPS
EEEECCHHHEEEECCCCC
>Mature Secondary Structure 
TILSASTRKKMHLISGAVLGIFVLCHFSNHALGLVSIGAMEVGRRIFTSVWHSVPGTVV
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCHHH
LYGALLLHFLMALDSLYRRQTFRMPAGEALKIVFGLSLPFLLVPHVVATRVEPLLTGIYP
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC
DYAGILRTLWSSSINASRQSLALIVVWGHACLGAWFWMRGRAWFPRYETLLYTVALLVPI
HHHHHHHHHHHCCCCCCCCCEEEEEEECHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
FALLGFVNGARSLERDYAEHGGYGDRAYAGASQERADPAVLESIRLAFYGGFAALIGATL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ALRAMPARGRIRIRYPDGRVAAVSLGFSVLEASRAAGIPHVSVCGGRGRCSTCRVRITQG
HHHCCCCCCEEEEECCCCCEEEEEHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEEECC
LENQPAPEAAELATLTRIGAPENIRLACQFRPVHNVSVVPILNTDSIGVKTQIARQNAGG
CCCCCCCCHHHHHHHHHCCCCCCEEEEEEEECCCCEEEEEEECCCCCCCCHHHHHCCCCC
RERRVAVLFCDLRDFTRIAEHRLPYDTVFLLNRYFEVVGEAVEGSGGVIDKFIGDGALAI
CCCEEEEEEECHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCEEEE
FGLKTPLPEACRQALSAAARLSQGIRALNQTFEGELDQPLRLAIGLHAGPAIIGEMGYGQ
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHEECCCCCC
ATSLTAVGDTINTASRLEGLAKEHDAELAVSAELVQRAGLAFEGHRRLEISLRGRQATLE
CCEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEECCCEEEEEEECCCEEEEE
TWIVGDASQLSLSLPSPS
EEEECCHHHEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9523018; 8418825 [H]