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The map label for this gene is lsrR [H]

Identifier: 150397559

GI number: 150397559

Start: 2435199

End: 2436152

Strand: Reverse

Name: lsrR [H]

Synonym: Smed_2359

Alternate gene names: 150397559

Gene position: 2436152-2435199 (Counterclockwise)

Preceding gene: 150397562

Following gene: 150397558

Centisome position: 64.42

GC content: 63.84

Gene sequence:

>954_bases
ATGGCACGCAAGGCGGAAGGCAACAACAGGCTCGACGATGCGGCCCGTGCGGGCTGGCTCTATTACGTCGCCGGCCGGAC
GCAGGACGAGATAGCGTCTGTCATGGGGATTTCGCGACAATCGGCGCAACGGCTCGTCTCGCTTGCCATGGCCGAGCGGC
TGATCAAGGTACGTCTGGACCATCCGATCGCCGCCTGCCTGGAAATGGCTGCGCGTCTTAAGGAGAAATACGACCTCAGA
CATGTCGACGTCGTACCGAGCGACCCCGGTTCCCAATCGTCGACCGTCGGCATCGCCGAGGCGGCAGCGGCGGAAATCGA
GCGCTGGCTGAAATCGACCGACCCGGTGGTGCTGGCGATCGGCACGGGCCGGACGCTGAAGGCGACGATCGATCAACTGC
CTTCGATGGAATGCCCCCAGCACCGCATCGTTTCCCTTACCGGCAACATCCGGCTCGACGGCTCCGCAGCCTATTATAAC
GTCATCTTCAGCATGGCGGACACGATCAAGGCACGGCACTTCCCGATGCCTTTGCCCGTTCTCGTCTCCTCACCGGAAGA
ACGGGAGGTCCTGCACAAGCAGAGCCTGGTGCAAATCGCCCTGGAGCTCGGCGCCGAGGCTGACGCCGCCTTCGTGGGCG
TCGGCGAACTCGGGCTCGACGCGCCGCTTTGCGAAGATGGTTTCCTGGCGCGCGACGAGATGAACAGGTTGATGGCCGCG
GGCGCTGCCGGCGAAATCTGCGGCTGGATGTTCGACCACGAAGGCGTGCTTCTTCAAGACAGCATCAATGAGCGTGTCGC
CTCCGTTCCCCTGCCGCCGCGCGACCGCGCCTCGGTCATCGGCATCGCCAAAGGCAGGCGCAAATACGGGGCCTTGCGCG
CCGCACTCCAAGGCAGGATCATCAACGGTCTCGTCACCGACGAGGCTACGGCCGATTATCTGCTCCGAGTCTGA

Upstream 100 bases:

>100_bases
AAAATCCGACCTTGCCGAAGGTATTTAAGCCCGATTGCACCTCCCGTTTGACAGCGCACCGGAAATGGTGGCAGCAAATC
AAGGGGAAGGGAGGCGGTCG

Downstream 100 bases:

>100_bases
GCCTGCCTTTTCCGGTCTCCCTTAAAAAATGCATAGCTAAAACACCTTCTTAGCCGTTGCCCCGCATCGGGGTGAAAATT
GCGGATTGACATTTAGGGTC

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MARKAEGNNRLDDAARAGWLYYVAGRTQDEIASVMGISRQSAQRLVSLAMAERLIKVRLDHPIAACLEMAARLKEKYDLR
HVDVVPSDPGSQSSTVGIAEAAAAEIERWLKSTDPVVLAIGTGRTLKATIDQLPSMECPQHRIVSLTGNIRLDGSAAYYN
VIFSMADTIKARHFPMPLPVLVSSPEEREVLHKQSLVQIALELGAEADAAFVGVGELGLDAPLCEDGFLARDEMNRLMAA
GAAGEICGWMFDHEGVLLQDSINERVASVPLPPRDRASVIGIAKGRRKYGALRAALQGRIINGLVTDEATADYLLRV

Sequences:

>Translated_317_residues
MARKAEGNNRLDDAARAGWLYYVAGRTQDEIASVMGISRQSAQRLVSLAMAERLIKVRLDHPIAACLEMAARLKEKYDLR
HVDVVPSDPGSQSSTVGIAEAAAAEIERWLKSTDPVVLAIGTGRTLKATIDQLPSMECPQHRIVSLTGNIRLDGSAAYYN
VIFSMADTIKARHFPMPLPVLVSSPEEREVLHKQSLVQIALELGAEADAAFVGVGELGLDAPLCEDGFLARDEMNRLMAA
GAAGEICGWMFDHEGVLLQDSINERVASVPLPPRDRASVIGIAKGRRKYGALRAALQGRIINGLVTDEATADYLLRV
>Mature_316_residues
ARKAEGNNRLDDAARAGWLYYVAGRTQDEIASVMGISRQSAQRLVSLAMAERLIKVRLDHPIAACLEMAARLKEKYDLRH
VDVVPSDPGSQSSTVGIAEAAAAEIERWLKSTDPVVLAIGTGRTLKATIDQLPSMECPQHRIVSLTGNIRLDGSAAYYNV
IFSMADTIKARHFPMPLPVLVSSPEEREVLHKQSLVQIALELGAEADAAFVGVGELGLDAPLCEDGFLARDEMNRLMAAG
AAGEICGWMFDHEGVLLQDSINERVASVPLPPRDRASVIGIAKGRRKYGALRAALQGRIINGLVTDEATADYLLRV

Specific function: Regulates transcription of many different genes. In the absence of autoinducer 2 (AI-2), represses transcription of the lsr operon and its own transcription. In the presence of AI-2, lsrR is inactivated by binding phospho-AI-2, leading to the transcriptio

COG id: COG2390

COG function: function code K; Transcriptional regulator, contains sigma factor-related N-terminal domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sorC transcriptional regulatory family [H]

Homologues:

Organism=Escherichia coli, GI1787791, Length=312, Percent_Identity=30.4487179487179, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI87082414, Length=311, Percent_Identity=25.7234726688103, Blast_Score=116, Evalue=2e-27,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04198 Sugar-bind [H]

EC number: NA

Molecular weight: Translated: 34337; Mature: 34206

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARKAEGNNRLDDAARAGWLYYVAGRTQDEIASVMGISRQSAQRLVSLAMAERLIKVRLD
CCCCCCCCCCHHHHHHCCEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC
HPIAACLEMAARLKEKYDLRHVDVVPSDPGSQSSTVGIAEAAAAEIERWLKSTDPVVLAI
CHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEE
GTGRTLKATIDQLPSMECPQHRIVSLTGNIRLDGSAAYYNVIFSMADTIKARHFPMPLPV
CCCCCHHHHHHHCCCCCCCCCEEEEEECCEEECCCHHHHHHHHHHHHHHHHCCCCCCCCC
LVSSPEEREVLHKQSLVQIALELGAEADAAFVGVGELGLDAPLCEDGFLARDEMNRLMAA
EECCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHC
GAAGEICGWMFDHEGVLLQDSINERVASVPLPPRDRASVIGIAKGRRKYGALRAALQGRI
CCCHHHHHHEECCCCEEEECCHHHHHHCCCCCCCCCCCEEEEHHCHHHHHHHHHHHHCHH
INGLVTDEATADYLLRV
HCCEECCCCCHHHHCCC
>Mature Secondary Structure 
ARKAEGNNRLDDAARAGWLYYVAGRTQDEIASVMGISRQSAQRLVSLAMAERLIKVRLD
CCCCCCCCCHHHHHHCCEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC
HPIAACLEMAARLKEKYDLRHVDVVPSDPGSQSSTVGIAEAAAAEIERWLKSTDPVVLAI
CHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEE
GTGRTLKATIDQLPSMECPQHRIVSLTGNIRLDGSAAYYNVIFSMADTIKARHFPMPLPV
CCCCCHHHHHHHCCCCCCCCCEEEEEECCEEECCCHHHHHHHHHHHHHHHHCCCCCCCCC
LVSSPEEREVLHKQSLVQIALELGAEADAAFVGVGELGLDAPLCEDGFLARDEMNRLMAA
EECCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHC
GAAGEICGWMFDHEGVLLQDSINERVASVPLPPRDRASVIGIAKGRRKYGALRAALQGRI
CCCHHHHHHEECCCCEEEECCHHHHHHCCCCCCCCCCCEEEEHHCHHHHHHHHHHHHCHH
INGLVTDEATADYLLRV
HCCEECCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA