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The map label for this gene is 150397544

Identifier: 150397544

GI number: 150397544

Start: 2420305

End: 2421807

Strand: Reverse

Name: 150397544

Synonym: Smed_2344

Alternate gene names: NA

Gene position: 2421807-2420305 (Counterclockwise)

Preceding gene: 150397545

Following gene: 150397536

Centisome position: 64.04

GC content: 63.07

Gene sequence:

>1503_bases
ATGCATGAAAAGACAGAGGCGATGCTCCCAGCCGTAGCGCAGGTGCTCGATGCGCCGGAACGGCTCGGCGTTCTTCAGGC
CGCGGTGCCGGACATGTCGATCCCAGACGGGGATTTCGACGGGCTTGCGGGGCTTGCGGCCAGCCTTTTCGATGCGCCGG
TCGCCCTCATCACCCTCGTGGACCACGAATGGCAGTGGTTCAAGGCTTCCGTCGGCACGGCGGAAACGCGGCTGCACGTT
CGTGAGTCGTTCTGCGTCCATACGATCGCAGAAGGCGACGGCGCCTTTGTCGTGCTCGATGCCTCTCGCCACCCGGCGTT
CAGACAGCGTCGGGCGGTCGCCGGCCCGCCCTCCGTGCGCTTCTATGCGGGCGCCCCGATCATTCTGGACGGGCAGGCGA
TAGGAACAGTCGCGGTCGTCGACGTCGCTCCCCGTTTCGAGATATCCGTCAAGCAGCAAGGCGAGCTGCAGCGCATCGCA
GGCGTCGCCGCCTCGCTGTTCAAACTGAAGGACGAAACACGCCGGCGTGCGCTCAAGGAGGCCGCGCTTTCCCGCGAAGA
GCAGCGGCTTGCCATGGCGCTCGATGCGGCCAATGTCGGCAGCTGGCTCTGGGACATTCGGGCCGGCACGGTTTCGGGCA
ACGGCGCAATGATGCGCATGTTCGGCCTTCCGCCAGAACGCACCGTTGGCGCCAAGGCCATATTTTCCGCCATCCATCCC
GACGATCGCATGCCGACCTTCTCGAAACTTCGCCAGGCGATGGCTGCCAATGAGGAATATGACGGCATGTTTCGCATCGG
CACCAATGGAAGGTGGCTGCTTGGCCGCGGCCGTGTGCACGACCGCGACAGCAAGGGTGCACCCTTGAGCTTTCTCGGCA
TGACGATCGATGTTTCGGAGCAGCAGGCGTCGGTGAACCGCACGCGGCTGCTGCTGAAGGAACTGAACCACCGGGTCAAG
AACACGCTGGCAATGCTCCAGTCACTCGCCCGCCAGACGCTTCGCCAGACGAGCGACCCGGCCGAATTCATGACCGCCTT
CGCCGGCAGGCTTCAGGCGATCTCCGAGGCGCATGGGCTCCTTTCCGATTACGAATGGGGCACGATCCACCTGTCCGAAC
TGATTTCGAAACAGTTGCTGCCCTATGTCAGCGATTACTCCCAACAGATCGAATTGCACAAGGATGAGATCCTGCTTGGT
CCGGACCAGGCCGTGGGGCTCGGGCTGGTTCTGCACGAACTGGCGACCAATGCCGTAAAATACGGCGCTCTCTCGCTGCC
GACGGGAAAAATCGTGCTGACGGCCCGCCGCTTAATCGAGGACGGAGAATCCGTGTTGCATCTGACCTGGACTGAAGTGG
GCGGCCCCCCGATTCGCGAGCCGCGCCGCCGCGGTTTCGGATCTATCCTGATCGAACGCAGCCTCGACAAGATCATCGGC
AGCTCGGTCAAGGTAGAATATCTGCCGGCGGGAGTCACCGCGTTGATCCGGCTGCCGCTTTGA

Upstream 100 bases:

>100_bases
CCAATTTGCTGTATGTTTTCATCATTGGACCGGCTCCGATCGACGAAAGCACACGGCGGAGCTCAATTTGGGTGCCTGTG
CGAGTTGGAGTTCAGGCCGG

Downstream 100 bases:

>100_bases
TCGAGTTCGGTTGAATTGCGGTTATCCGGCTGCCGGAACCTTCTCTCCGCAAGCAGGGCAAAGGTGCATGCTGGCAGCTC
CGAACTATCCGTCATCGCCG

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MHEKTEAMLPAVAQVLDAPERLGVLQAAVPDMSIPDGDFDGLAGLAASLFDAPVALITLVDHEWQWFKASVGTAETRLHV
RESFCVHTIAEGDGAFVVLDASRHPAFRQRRAVAGPPSVRFYAGAPIILDGQAIGTVAVVDVAPRFEISVKQQGELQRIA
GVAASLFKLKDETRRRALKEAALSREEQRLAMALDAANVGSWLWDIRAGTVSGNGAMMRMFGLPPERTVGAKAIFSAIHP
DDRMPTFSKLRQAMAANEEYDGMFRIGTNGRWLLGRGRVHDRDSKGAPLSFLGMTIDVSEQQASVNRTRLLLKELNHRVK
NTLAMLQSLARQTLRQTSDPAEFMTAFAGRLQAISEAHGLLSDYEWGTIHLSELISKQLLPYVSDYSQQIELHKDEILLG
PDQAVGLGLVLHELATNAVKYGALSLPTGKIVLTARRLIEDGESVLHLTWTEVGGPPIREPRRRGFGSILIERSLDKIIG
SSVKVEYLPAGVTALIRLPL

Sequences:

>Translated_500_residues
MHEKTEAMLPAVAQVLDAPERLGVLQAAVPDMSIPDGDFDGLAGLAASLFDAPVALITLVDHEWQWFKASVGTAETRLHV
RESFCVHTIAEGDGAFVVLDASRHPAFRQRRAVAGPPSVRFYAGAPIILDGQAIGTVAVVDVAPRFEISVKQQGELQRIA
GVAASLFKLKDETRRRALKEAALSREEQRLAMALDAANVGSWLWDIRAGTVSGNGAMMRMFGLPPERTVGAKAIFSAIHP
DDRMPTFSKLRQAMAANEEYDGMFRIGTNGRWLLGRGRVHDRDSKGAPLSFLGMTIDVSEQQASVNRTRLLLKELNHRVK
NTLAMLQSLARQTLRQTSDPAEFMTAFAGRLQAISEAHGLLSDYEWGTIHLSELISKQLLPYVSDYSQQIELHKDEILLG
PDQAVGLGLVLHELATNAVKYGALSLPTGKIVLTARRLIEDGESVLHLTWTEVGGPPIREPRRRGFGSILIERSLDKIIG
SSVKVEYLPAGVTALIRLPL
>Mature_500_residues
MHEKTEAMLPAVAQVLDAPERLGVLQAAVPDMSIPDGDFDGLAGLAASLFDAPVALITLVDHEWQWFKASVGTAETRLHV
RESFCVHTIAEGDGAFVVLDASRHPAFRQRRAVAGPPSVRFYAGAPIILDGQAIGTVAVVDVAPRFEISVKQQGELQRIA
GVAASLFKLKDETRRRALKEAALSREEQRLAMALDAANVGSWLWDIRAGTVSGNGAMMRMFGLPPERTVGAKAIFSAIHP
DDRMPTFSKLRQAMAANEEYDGMFRIGTNGRWLLGRGRVHDRDSKGAPLSFLGMTIDVSEQQASVNRTRLLLKELNHRVK
NTLAMLQSLARQTLRQTSDPAEFMTAFAGRLQAISEAHGLLSDYEWGTIHLSELISKQLLPYVSDYSQQIELHKDEILLG
PDQAVGLGLVLHELATNAVKYGALSLPTGKIVLTARRLIEDGESVLHLTWTEVGGPPIREPRRRGFGSILIERSLDKIIG
SSVKVEYLPAGVTALIRLPL

Specific function: Photosensitive kinase that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR013655
- InterPro:   IPR011102 [H]

Pfam domain/function: PF07536 HWE_HK; PF00989 PAS; PF08447 PAS_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 54633; Mature: 54633

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS50112 PAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEKTEAMLPAVAQVLDAPERLGVLQAAVPDMSIPDGDFDGLAGLAASLFDAPVALITLV
CCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEEE
DHEWQWFKASVGTAETRLHVRESFCVHTIAEGDGAFVVLDASRHPAFRQRRAVAGPPSVR
CCCCEEEEECCCCHHHHHHHHHHHHEEEEECCCCEEEEEECCCCCHHHHHCCCCCCCCEE
FYAGAPIILDGQAIGTVAVVDVAPRFEISVKQQGELQRIAGVAASLFKLKDETRRRALKE
EEECCCEEECCCCCCEEEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AALSREEQRLAMALDAANVGSWLWDIRAGTVSGNGAMMRMFGLPPERTVGAKAIFSAIHP
HHHCHHHHHHHHHHHHHHHCCCEEEEEECEECCCCCEEEEECCCCCCCHHHHHHHHHCCC
DDRMPTFSKLRQAMAANEEYDGMFRIGTNGRWLLGRGRVHDRDSKGAPLSFLGMTIDVSE
CCCCCHHHHHHHHHHCCCCCCCEEEECCCCEEEEECCCCCCCCCCCCCEEEEEEEEECCH
QQASVNRTRLLLKELNHRVKNTLAMLQSLARQTLRQTSDPAEFMTAFAGRLQAISEAHGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
LSDYEWGTIHLSELISKQLLPYVSDYSQQIELHKDEILLGPDQAVGLGLVLHELATNAVK
HCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHH
YGALSLPTGKIVLTARRLIEDGESVLHLTWTEVGGPPIREPRRRGFGSILIERSLDKIIG
CCEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHCCCHHHHHHHHHHHHHC
SSVKVEYLPAGVTALIRLPL
CCEEEEEECCCEEEEEECCC
>Mature Secondary Structure
MHEKTEAMLPAVAQVLDAPERLGVLQAAVPDMSIPDGDFDGLAGLAASLFDAPVALITLV
CCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEEE
DHEWQWFKASVGTAETRLHVRESFCVHTIAEGDGAFVVLDASRHPAFRQRRAVAGPPSVR
CCCCEEEEECCCCHHHHHHHHHHHHEEEEECCCCEEEEEECCCCCHHHHHCCCCCCCCEE
FYAGAPIILDGQAIGTVAVVDVAPRFEISVKQQGELQRIAGVAASLFKLKDETRRRALKE
EEECCCEEECCCCCCEEEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AALSREEQRLAMALDAANVGSWLWDIRAGTVSGNGAMMRMFGLPPERTVGAKAIFSAIHP
HHHCHHHHHHHHHHHHHHHCCCEEEEEECEECCCCCEEEEECCCCCCCHHHHHHHHHCCC
DDRMPTFSKLRQAMAANEEYDGMFRIGTNGRWLLGRGRVHDRDSKGAPLSFLGMTIDVSE
CCCCCHHHHHHHHHHCCCCCCCEEEECCCCEEEEECCCCCCCCCCCCCEEEEEEEEECCH
QQASVNRTRLLLKELNHRVKNTLAMLQSLARQTLRQTSDPAEFMTAFAGRLQAISEAHGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
LSDYEWGTIHLSELISKQLLPYVSDYSQQIELHKDEILLGPDQAVGLGLVLHELATNAVK
HCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHH
YGALSLPTGKIVLTARRLIEDGESVLHLTWTEVGGPPIREPRRRGFGSILIERSLDKIIG
CCEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHCCCHHHHHHHHHHHHHC
SSVKVEYLPAGVTALIRLPL
CCEEEEEECCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA