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The map label for this gene is ddpA [H]

Identifier: 150397526

GI number: 150397526

Start: 2407024

End: 2408664

Strand: Reverse

Name: ddpA [H]

Synonym: Smed_2326

Alternate gene names: 150397526

Gene position: 2408664-2407024 (Counterclockwise)

Preceding gene: 150397527

Following gene: 150397525

Centisome position: 63.69

GC content: 58.99

Gene sequence:

>1641_bases
ATGATGCACAAGCTCAATGGACGTTTTCGAATTCTCGCCGCCTCGGCGGCCCTCGCCATGGCGATGGGCGCGGCTCAGCC
GGCCTTCGCGGAAACGCCGAAGGACACGCTGGTCGAGGGTTTCGCATTCGACGACATCATCACCATGGATCCCGGCGAAG
CCTTCGAGCTTTCGACCGCCGAGATGACGAGCAATACCTACAGCCTGCTCGTGAGGCTCGATCTCAACGATACCTCCAAG
GTCGTAGGCGATCTTGCGGAAAGCTGGACGGTCTCGGATGACGGCCTGACCTATACGTTCAAGCTCAAGCCGGGAATGAA
ATTCGCATCCGGCAATCCGATCACCGCCGAGGACGTCGCCTATTCGTTCGAACGTGCCGTCAAGCTCGACAAGAGCCCGG
CCTTCATCCTCACCCAGTTCGGCCTTACCGGGGACAATGTCACGGAAAAGGCGAAGGCCGCCGACCCGGAGACCTTTGTT
TTCACGGTCGACCAGCCCTACGCGCCGAGTTTCGTCTTGAACTGTCTGACCGCGACGGTTGCTTCCGTAGTCGACAAGAA
GCTCGTGCTCGAACATGTGAAATCCGTGTCGCCGAGCGACGAGTACAAGTATGACAACGACTTCGGCAATGAGTGGCTGA
AGACCGGTTATGCCGGTTCCGGTCCGTTCAAGCTGCGCGAGTGGCGCGCCAATGAAGTCGTGGTGCTGGAACGCAACGAC
AATTATTATGGCGAACCGGCGAAACTCGCCCGCGTCATCTACCGTCACATGAAGGAAAGCTCGGGTCAGCGGCTCGCGCT
TGAAGCCGGCGACATCGATGTCGCGCGCAACCTCGAGCCCGGCGACTACGACGCAGTCGGCAAGAATGCCGATCTGGCGA
CGGCCAGCGCCCCGAAGGGAACGGTCTACTATATCAGCCTCAATCAGAAGAACGAAAAGCTCGCAAAACCCGAGGTACAG
CAGGCGTTCAAGTATCTTGTCGATTACGACGCGATTGGCTCGACCCTGATCAAGGGCATCGGCGAGATTCACCAGAGCTT
CCTGCCGAAGGGTGTGCTGGGTGCCGTCGACGAGAACCCCTACACCTTCGACGTAGCCAAGGCGAAGGAACTGCTGGCGA
AGGCCGGCTATCCGGACGGCTTCACCGTTACGATGGATGTGCGTAATACCCAGCCGGTCACCGGCATTGCCGAATCCTTC
CAGCAGACGCTGGGGCAGGCGGGCGTGAAGCTCGAAATTATTCCAGGAGACGGCAAGCAGACCCTGACCAAGTACCGCGC
CCGCAATCACGACATGTATATCGGCCAGTGGGGCATGGATTATTTCGATCCGCACTCCAATGCCGATACCTTCACCAACA
ATCCGGACAATTCCGACGAAGGCACGAACAAGACGCTCGCCTGGCGCAACGCCTGGGACGTTCCGGAACTCAGCAAGAAG
ACCAAGGACGCGCTCCTCGAACGCGACAGCACAAAGCGCGCCGAGATCTACAAGGAGCTGCAGAAAACGGTGCTCGAGGA
CAGTCCTTTCGTCGTCATCTTCCAGCAGACAGAGGTCGCCGGGTTGCGCGGCATTGTCGAGGGCTTCAAGCTCGGGCCGA
GCTTCGACACCAACTACGTCTGGAACGTCTCCAAGGAATAG

Upstream 100 bases:

>100_bases
GCCGGGAGAACTGGTTGAGAGTTCTGGGACAGGCCTGGCACGAGCCCGCCTGATCATCATGAAGAAGAGCCCGAGAAGGG
TTAAAAGAGGGAAGCGCAAT

Downstream 100 bases:

>100_bases
TCGAAAGGACCGTTCCCTTGAGCATCATCGGAACAGAACCAATGAGCGGGCGCCGGCGCGCCCGTTCCCGGAAGGCGTTT
GTCGCCGCGCTGCAGTTTCT

Product: extracellular solute-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 546; Mature: 546

Protein sequence:

>546_residues
MMHKLNGRFRILAASAALAMAMGAAQPAFAETPKDTLVEGFAFDDIITMDPGEAFELSTAEMTSNTYSLLVRLDLNDTSK
VVGDLAESWTVSDDGLTYTFKLKPGMKFASGNPITAEDVAYSFERAVKLDKSPAFILTQFGLTGDNVTEKAKAADPETFV
FTVDQPYAPSFVLNCLTATVASVVDKKLVLEHVKSVSPSDEYKYDNDFGNEWLKTGYAGSGPFKLREWRANEVVVLERND
NYYGEPAKLARVIYRHMKESSGQRLALEAGDIDVARNLEPGDYDAVGKNADLATASAPKGTVYYISLNQKNEKLAKPEVQ
QAFKYLVDYDAIGSTLIKGIGEIHQSFLPKGVLGAVDENPYTFDVAKAKELLAKAGYPDGFTVTMDVRNTQPVTGIAESF
QQTLGQAGVKLEIIPGDGKQTLTKYRARNHDMYIGQWGMDYFDPHSNADTFTNNPDNSDEGTNKTLAWRNAWDVPELSKK
TKDALLERDSTKRAEIYKELQKTVLEDSPFVVIFQQTEVAGLRGIVEGFKLGPSFDTNYVWNVSKE

Sequences:

>Translated_546_residues
MMHKLNGRFRILAASAALAMAMGAAQPAFAETPKDTLVEGFAFDDIITMDPGEAFELSTAEMTSNTYSLLVRLDLNDTSK
VVGDLAESWTVSDDGLTYTFKLKPGMKFASGNPITAEDVAYSFERAVKLDKSPAFILTQFGLTGDNVTEKAKAADPETFV
FTVDQPYAPSFVLNCLTATVASVVDKKLVLEHVKSVSPSDEYKYDNDFGNEWLKTGYAGSGPFKLREWRANEVVVLERND
NYYGEPAKLARVIYRHMKESSGQRLALEAGDIDVARNLEPGDYDAVGKNADLATASAPKGTVYYISLNQKNEKLAKPEVQ
QAFKYLVDYDAIGSTLIKGIGEIHQSFLPKGVLGAVDENPYTFDVAKAKELLAKAGYPDGFTVTMDVRNTQPVTGIAESF
QQTLGQAGVKLEIIPGDGKQTLTKYRARNHDMYIGQWGMDYFDPHSNADTFTNNPDNSDEGTNKTLAWRNAWDVPELSKK
TKDALLERDSTKRAEIYKELQKTVLEDSPFVVIFQQTEVAGLRGIVEGFKLGPSFDTNYVWNVSKE
>Mature_546_residues
MMHKLNGRFRILAASAALAMAMGAAQPAFAETPKDTLVEGFAFDDIITMDPGEAFELSTAEMTSNTYSLLVRLDLNDTSK
VVGDLAESWTVSDDGLTYTFKLKPGMKFASGNPITAEDVAYSFERAVKLDKSPAFILTQFGLTGDNVTEKAKAADPETFV
FTVDQPYAPSFVLNCLTATVASVVDKKLVLEHVKSVSPSDEYKYDNDFGNEWLKTGYAGSGPFKLREWRANEVVVLERND
NYYGEPAKLARVIYRHMKESSGQRLALEAGDIDVARNLEPGDYDAVGKNADLATASAPKGTVYYISLNQKNEKLAKPEVQ
QAFKYLVDYDAIGSTLIKGIGEIHQSFLPKGVLGAVDENPYTFDVAKAKELLAKAGYPDGFTVTMDVRNTQPVTGIAESF
QQTLGQAGVKLEIIPGDGKQTLTKYRARNHDMYIGQWGMDYFDPHSNADTFTNNPDNSDEGTNKTLAWRNAWDVPELSKK
TKDALLERDSTKRAEIYKELQKTVLEDSPFVVIFQQTEVAGLRGIVEGFKLGPSFDTNYVWNVSKE

Specific function: Part of the ABC transporter complex ddpABCDF, which is probably involved in D,D-dipeptide transport [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787762, Length=533, Percent_Identity=29.4559099437148, Blast_Score=189, Evalue=5e-49,
Organism=Escherichia coli, GI1787052, Length=496, Percent_Identity=25, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1789966, Length=498, Percent_Identity=25.5020080321285, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1789887, Length=513, Percent_Identity=26.1208576998051, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1787551, Length=552, Percent_Identity=24.4565217391304, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI87081878, Length=522, Percent_Identity=23.7547892720307, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789397, Length=513, Percent_Identity=25.1461988304094, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI1787495, Length=563, Percent_Identity=23.8010657193606, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60267; Mature: 60267

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMHKLNGRFRILAASAALAMAMGAAQPAFAETPKDTLVEGFAFDDIITMDPGEAFELSTA
CCCCCCCCEEEEEHHHHHHHHHCCCCCCCCCCCHHHHHCCEECCCEEEECCCCCEEEEHH
EMTSNTYSLLVRLDLNDTSKVVGDLAESWTVSDDGLTYTFKLKPGMKFASGNPITAEDVA
HHCCCEEEEEEEEECCCHHHHHHHHHHHCEECCCCEEEEEEECCCCEECCCCCCCHHHHH
YSFERAVKLDKSPAFILTQFGLTGDNVTEKAKAADPETFVFTVDQPYAPSFVLNCLTATV
HHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHH
ASVVDKKLVLEHVKSVSPSDEYKYDNDFGNEWLKTGYAGSGPFKLREWRANEVVVLERND
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCCCCEEEEECCCEEEEEECCC
NYYGEPAKLARVIYRHMKESSGQRLALEAGDIDVARNLEPGDYDAVGKNADLATASAPKG
CCCCCHHHHHHHHHHHHHHCCCCEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCCC
TVYYISLNQKNEKLAKPEVQQAFKYLVDYDAIGSTLIKGIGEIHQSFLPKGVLGAVDENP
EEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCC
YTFDVAKAKELLAKAGYPDGFTVTMDVRNTQPVTGIAESFQQTLGQAGVKLEIIPGDGKQ
CEEEHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCCHH
TLTKYRARNHDMYIGQWGMDYFDPHSNADTFTNNPDNSDEGTNKTLAWRNAWDVPELSKK
HHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHH
TKDALLERDSTKRAEIYKELQKTVLEDSPFVVIFQQTEVAGLRGIVEGFKLGPSFDTNYV
HHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCEE
WNVSKE
EEECCC
>Mature Secondary Structure
MMHKLNGRFRILAASAALAMAMGAAQPAFAETPKDTLVEGFAFDDIITMDPGEAFELSTA
CCCCCCCCEEEEEHHHHHHHHHCCCCCCCCCCCHHHHHCCEECCCEEEECCCCCEEEEHH
EMTSNTYSLLVRLDLNDTSKVVGDLAESWTVSDDGLTYTFKLKPGMKFASGNPITAEDVA
HHCCCEEEEEEEEECCCHHHHHHHHHHHCEECCCCEEEEEEECCCCEECCCCCCCHHHHH
YSFERAVKLDKSPAFILTQFGLTGDNVTEKAKAADPETFVFTVDQPYAPSFVLNCLTATV
HHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHH
ASVVDKKLVLEHVKSVSPSDEYKYDNDFGNEWLKTGYAGSGPFKLREWRANEVVVLERND
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCCCCEEEEECCCEEEEEECCC
NYYGEPAKLARVIYRHMKESSGQRLALEAGDIDVARNLEPGDYDAVGKNADLATASAPKG
CCCCCHHHHHHHHHHHHHHCCCCEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCCC
TVYYISLNQKNEKLAKPEVQQAFKYLVDYDAIGSTLIKGIGEIHQSFLPKGVLGAVDENP
EEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCC
YTFDVAKAKELLAKAGYPDGFTVTMDVRNTQPVTGIAESFQQTLGQAGVKLEIIPGDGKQ
CEEEHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCCHH
TLTKYRARNHDMYIGQWGMDYFDPHSNADTFTNNPDNSDEGTNKTLAWRNAWDVPELSKK
HHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHH
TKDALLERDSTKRAEIYKELQKTVLEDSPFVVIFQQTEVAGLRGIVEGFKLGPSFDTNYV
HHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCEE
WNVSKE
EEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9751644 [H]