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The map label for this gene is 150397527

Identifier: 150397527

GI number: 150397527

Start: 2408712

End: 2409773

Strand: Reverse

Name: 150397527

Synonym: Smed_2327

Alternate gene names: NA

Gene position: 2409773-2408712 (Counterclockwise)

Preceding gene: 150397528

Following gene: 150397526

Centisome position: 63.72

GC content: 63.47

Gene sequence:

>1062_bases
TTGGGAATGCAGGCGGTTTTCGACGGCCACAACGATGTACTTTTGCGCCTCTGGCAGCATGCGCGCGGCGGTGCCGATCC
GGTCGTGGAGTTTCTGGAGGGCACGGACAAGGGCCACATCGATGCAGGGCGCGCCAAGGCGGGAGGGCTTTCAGGCGGAC
TTTGTGCGATTTACGTTCCATCCGGCGATCTCGTACTCAAGACACCGGATGAGAATGGCCATTACGCGACGCCTATGGCG
GCGCCGCTCGACCACCTGCCATCGCTCGCAACCGCCATGGAACTTGCCGATATTGCAATCAAGCTCGACCGTGCCGGCGC
CTGGCGGCTTTGTCGTTCCGTTGGCGAGATACGTGCGGCGATGGCGGTCGAGGTGTTCGCTGCCGTCCTGCACATGGAGG
GCTGCGAGGCGATCGGACCCGATCTTGCCGCGCTCGAGACGTTCCACGCCGCGGGGCTTCGTTCACTGGGTCCCGTTTGG
AGCCGTCACAACGTGTTCGGTCACGGCGTTCCCTTCGCCTATCCGATGTCGCCTGACACGGGTCCAGGCCTGACAGAAGC
CGGCTTCGAGCTCGTGCGCGCCTGCAATCGGCTCGGCATTCTGATCGATCTGGCTCACATCACGGAGCAAGGCTTCTGGG
ACGTCGCCAAGACGACCGACCAACCGCTGGTCGCCAGCCACTCCAATGCTCATGCGCTGACGCCCGTCGCGCGCAATTTG
ACCGACAGGCAGCTCGATGCGATCAGAGAGAGCCGCGGGCTCGTCGGCCTCAATTACGCGACGACGATGCTGCGCCCGGA
CGGGCAGGAAAACGCGTCGACCCTGCTTTCCGACATGGTGCGCCATGTCGACTATCTCGTCGAGCGCCTTGGCGTCGATT
GCGTGGCACTTGGATCGGACTTCGACGGCGCGACCATCCCGGAGGAAATTGCCGACGCCGCGGGAAATCAGAAGCTCGTT
GCCGCGCTGATGGACGCCGGATATGGTGACGCCGAACTGGCGAAAATATGCCGGGAGAACTGGTTGAGAGTTCTGGGACA
GGCCTGGCACGAGCCCGCCTGA

Upstream 100 bases:

>100_bases
CATTGAAATGCGCGGCGCGCTTCAATAGCATCGCGCTTCCTCTCGTCCGGACGGGACGAGGCGACATCCATTCCGATCCC
CTTGATATACGAAGGAAAAC

Downstream 100 bases:

>100_bases
TCATCATGAAGAAGAGCCCGAGAAGGGTTAAAAGAGGGAAGCGCAATATGATGCACAAGCTCAATGGACGTTTTCGAATT
CTCGCCGCCTCGGCGGCCCT

Product: peptidase M19 renal dipeptidase

Products: NA

Alternate protein names: ORF X [H]

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MGMQAVFDGHNDVLLRLWQHARGGADPVVEFLEGTDKGHIDAGRAKAGGLSGGLCAIYVPSGDLVLKTPDENGHYATPMA
APLDHLPSLATAMELADIAIKLDRAGAWRLCRSVGEIRAAMAVEVFAAVLHMEGCEAIGPDLAALETFHAAGLRSLGPVW
SRHNVFGHGVPFAYPMSPDTGPGLTEAGFELVRACNRLGILIDLAHITEQGFWDVAKTTDQPLVASHSNAHALTPVARNL
TDRQLDAIRESRGLVGLNYATTMLRPDGQENASTLLSDMVRHVDYLVERLGVDCVALGSDFDGATIPEEIADAAGNQKLV
AALMDAGYGDAELAKICRENWLRVLGQAWHEPA

Sequences:

>Translated_353_residues
MGMQAVFDGHNDVLLRLWQHARGGADPVVEFLEGTDKGHIDAGRAKAGGLSGGLCAIYVPSGDLVLKTPDENGHYATPMA
APLDHLPSLATAMELADIAIKLDRAGAWRLCRSVGEIRAAMAVEVFAAVLHMEGCEAIGPDLAALETFHAAGLRSLGPVW
SRHNVFGHGVPFAYPMSPDTGPGLTEAGFELVRACNRLGILIDLAHITEQGFWDVAKTTDQPLVASHSNAHALTPVARNL
TDRQLDAIRESRGLVGLNYATTMLRPDGQENASTLLSDMVRHVDYLVERLGVDCVALGSDFDGATIPEEIADAAGNQKLV
AALMDAGYGDAELAKICRENWLRVLGQAWHEPA
>Mature_352_residues
GMQAVFDGHNDVLLRLWQHARGGADPVVEFLEGTDKGHIDAGRAKAGGLSGGLCAIYVPSGDLVLKTPDENGHYATPMAA
PLDHLPSLATAMELADIAIKLDRAGAWRLCRSVGEIRAAMAVEVFAAVLHMEGCEAIGPDLAALETFHAAGLRSLGPVWS
RHNVFGHGVPFAYPMSPDTGPGLTEAGFELVRACNRLGILIDLAHITEQGFWDVAKTTDQPLVASHSNAHALTPVARNLT
DRQLDAIRESRGLVGLNYATTMLRPDGQENASTLLSDMVRHVDYLVERLGVDCVALGSDFDGATIPEEIADAAGNQKLVA
ALMDAGYGDAELAKICRENWLRVLGQAWHEPA

Specific function: Unknown

COG id: COG2355

COG function: function code E; Zn-dependent dipeptidase, microsomal dipeptidase homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M19 family [H]

Homologues:

Organism=Homo sapiens, GI189458885, Length=352, Percent_Identity=25.8522727272727, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI4758190, Length=352, Percent_Identity=25.8522727272727, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI11641269, Length=349, Percent_Identity=25.214899713467, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI193211608, Length=350, Percent_Identity=23.4285714285714, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI193211610, Length=350, Percent_Identity=23.4285714285714, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI221475880, Length=353, Percent_Identity=26.628895184136, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI281362638, Length=359, Percent_Identity=25.3481894150418, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI281362636, Length=359, Percent_Identity=25.3481894150418, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI161083233, Length=264, Percent_Identity=29.1666666666667, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008257 [H]

Pfam domain/function: PF01244 Peptidase_M19 [H]

EC number: NA

Molecular weight: Translated: 37649; Mature: 37518

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGMQAVFDGHNDVLLRLWQHARGGADPVVEFLEGTDKGHIDAGRAKAGGLSGGLCAIYVP
CCCCCEECCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEC
SGDLVLKTPDENGHYATPMAAPLDHLPSLATAMELADIAIKLDRAGAWRLCRSVGEIRAA
CCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHH
MAVEVFAAVLHMEGCEAIGPDLAALETFHAAGLRSLGPVWSRHNVFGHGVPFAYPMSPDT
HHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCEEECCCCCC
GPGLTEAGFELVRACNRLGILIDLAHITEQGFWDVAKTTDQPLVASHSNAHALTPVARNL
CCCHHHHHHHHHHHHHHHHHHEEHHHHHCCCCHHHHHCCCCCCEECCCCCCCHHHHHHCC
TDRQLDAIRESRGLVGLNYATTMLRPDGQENASTLLSDMVRHVDYLVERLGVDCVALGSD
HHHHHHHHHHHCCCEEECHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCC
FDGATIPEEIADAAGNQKLVAALMDAGYGDAELAKICRENWLRVLGQAWHEPA
CCCCCCCHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GMQAVFDGHNDVLLRLWQHARGGADPVVEFLEGTDKGHIDAGRAKAGGLSGGLCAIYVP
CCCCEECCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEC
SGDLVLKTPDENGHYATPMAAPLDHLPSLATAMELADIAIKLDRAGAWRLCRSVGEIRAA
CCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHH
MAVEVFAAVLHMEGCEAIGPDLAALETFHAAGLRSLGPVWSRHNVFGHGVPFAYPMSPDT
HHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCEEECCCCCC
GPGLTEAGFELVRACNRLGILIDLAHITEQGFWDVAKTTDQPLVASHSNAHALTPVARNL
CCCHHHHHHHHHHHHHHHHHHEEHHHHHCCCCHHHHHCCCCCCEECCCCCCCHHHHHHCC
TDRQLDAIRESRGLVGLNYATTMLRPDGQENASTLLSDMVRHVDYLVERLGVDCVALGSD
HHHHHHHHHHHCCCEEECHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCC
FDGATIPEEIADAAGNQKLVAALMDAGYGDAELAKICRENWLRVLGQAWHEPA
CCCCCCCHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1313537 [H]