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The map label for this gene is hdfR [H]

Identifier: 150397400

GI number: 150397400

Start: 2280123

End: 2280968

Strand: Direct

Name: hdfR [H]

Synonym: Smed_2199

Alternate gene names: 150397400

Gene position: 2280123-2280968 (Clockwise)

Preceding gene: 150397396

Following gene: 150397402

Centisome position: 60.29

GC content: 62.17

Gene sequence:

>846_bases
ATGCAGGTTGACCTGATCGAGACCTTTCTTGACCTGATGGAAACGCGCAGTTTCAACCGTACGGCTGAACGGCTGAACAT
CACGCAATCCACGGTTTCGCACCGCGTGAAGGCGCTGGAGGCGCAATTCAACCGGAAACTCTTCACGCGCAACAAGGGCG
GGACCCTCCCGACGGCTGCCGGTCTGCGGTTTCTCGACTACGCCAAAGCTTTGCAAAATCAGTGGCATGAAGCGACGCGC
GCAGTGGCGAGCGCAGGCGCCCTCGAGCGATCGATGCGGCTTGGAATTCAGCACGATCTGGCCGAGACCATTGCAGGCCG
ATGGGTGGCTGCGATCCGCCGCGATCTGCCGACGACCGAGATCTATATGGAAGCGGATTATTCGAACCAGATGAACCGCG
ATCTCGCCGCCGGAGAGCTCGATCTCGCAGTGCTCTACACGCCGCACTTCCTGCCCGATCTTCACTATGAACGGATCGGC
GAACTGCATTACGTGCTCGTCAGCACCGATACGCACGACTTGGCCGGCGTGAGGCCCGAAACCTACATCCGATCAAGCTA
CTCGCCGGCCTTTGATCGTGCGCACCGCCTGGCACTTCCGCACCTTTCGGCGGCTACTCTTTCAGCCGGCCAGAACATGG
CGGTGATGGACCTGTTGCGCACGCTCGGCGGCGCGGCCTATGTGACGCAGGCGACCGCCGACCAGATCTCCGACCGCGTT
GCCGTCGTGGCCGATGCGCCGGTCATCCCGCAGACCGTTTACGCCGCAACGAGCCTGCGCACCCGCCACGCCCACCAGCA
CCGCAAGATCATCGGCGCGATGGAGGGCCTGTTGGTGGAGTTGTAA

Upstream 100 bases:

>100_bases
TTTTTGACGAGGAAGCTGAAGTCCATCAAGCGCCGCGAGGCGGCTTTATTAATCGATGAATTCGATTAGATTGCCGAGGG
GGATGCAAGGAGCGGCACCT

Downstream 100 bases:

>100_bases
ACGCATCCACCGCTACCGCCCATCGGTCCTCGCCCGATCAACGCGCGGAGAATTGCGCTTTCAGCCGCGCCACATCCGCC
GCCGTAATCCCCGGCGGATC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: H-NS-dependent flhDC regulator [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MQVDLIETFLDLMETRSFNRTAERLNITQSTVSHRVKALEAQFNRKLFTRNKGGTLPTAAGLRFLDYAKALQNQWHEATR
AVASAGALERSMRLGIQHDLAETIAGRWVAAIRRDLPTTEIYMEADYSNQMNRDLAAGELDLAVLYTPHFLPDLHYERIG
ELHYVLVSTDTHDLAGVRPETYIRSSYSPAFDRAHRLALPHLSAATLSAGQNMAVMDLLRTLGGAAYVTQATADQISDRV
AVVADAPVIPQTVYAATSLRTRHAHQHRKIIGAMEGLLVEL

Sequences:

>Translated_281_residues
MQVDLIETFLDLMETRSFNRTAERLNITQSTVSHRVKALEAQFNRKLFTRNKGGTLPTAAGLRFLDYAKALQNQWHEATR
AVASAGALERSMRLGIQHDLAETIAGRWVAAIRRDLPTTEIYMEADYSNQMNRDLAAGELDLAVLYTPHFLPDLHYERIG
ELHYVLVSTDTHDLAGVRPETYIRSSYSPAFDRAHRLALPHLSAATLSAGQNMAVMDLLRTLGGAAYVTQATADQISDRV
AVVADAPVIPQTVYAATSLRTRHAHQHRKIIGAMEGLLVEL
>Mature_281_residues
MQVDLIETFLDLMETRSFNRTAERLNITQSTVSHRVKALEAQFNRKLFTRNKGGTLPTAAGLRFLDYAKALQNQWHEATR
AVASAGALERSMRLGIQHDLAETIAGRWVAAIRRDLPTTEIYMEADYSNQMNRDLAAGELDLAVLYTPHFLPDLHYERIG
ELHYVLVSTDTHDLAGVRPETYIRSSYSPAFDRAHRLALPHLSAATLSAGQNMAVMDLLRTLGGAAYVTQATADQISDRV
AVVADAPVIPQTVYAATSLRTRHAHQHRKIIGAMEGLLVEL

Specific function: Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994962, Length=264, Percent_Identity=26.1363636363636, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1788297, Length=143, Percent_Identity=30.7692307692308, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020890
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31246; Mature: 31246

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVDLIETFLDLMETRSFNRTAERLNITQSTVSHRVKALEAQFNRKLFTRNKGGTLPTAA
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
GLRFLDYAKALQNQWHEATRAVASAGALERSMRLGIQHDLAETIAGRWVAAIRRDLPTTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCE
IYMEADYSNQMNRDLAAGELDLAVLYTPHFLPDLHYERIGELHYVLVSTDTHDLAGVRPE
EEEECCCCCHHCCCCCCCCCCEEEEECCCCCCCCCHHHHCCEEEEEEECCCHHHCCCCHH
TYIRSSYSPAFDRAHRLALPHLSAATLSAGQNMAVMDLLRTLGGAAYVTQATADQISDRV
HHHHCCCCHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCE
AVVADAPVIPQTVYAATSLRTRHAHQHRKIIGAMEGLLVEL
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQVDLIETFLDLMETRSFNRTAERLNITQSTVSHRVKALEAQFNRKLFTRNKGGTLPTAA
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
GLRFLDYAKALQNQWHEATRAVASAGALERSMRLGIQHDLAETIAGRWVAAIRRDLPTTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCE
IYMEADYSNQMNRDLAAGELDLAVLYTPHFLPDLHYERIGELHYVLVSTDTHDLAGVRPE
EEEECCCCCHHCCCCCCCCCCEEEEECCCCCCCCCHHHHCCEEEEEEECCCHHHCCCCHH
TYIRSSYSPAFDRAHRLALPHLSAATLSAGQNMAVMDLLRTLGGAAYVTQATADQISDRV
HHHHCCCCHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCE
AVVADAPVIPQTVYAATSLRTRHAHQHRKIIGAMEGLLVEL
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA