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The map label for this gene is yngJ [H]

Identifier: 150397376

GI number: 150397376

Start: 2246380

End: 2247540

Strand: Direct

Name: yngJ [H]

Synonym: Smed_2175

Alternate gene names: 150397376

Gene position: 2246380-2247540 (Clockwise)

Preceding gene: 150397375

Following gene: 150397377

Centisome position: 59.4

GC content: 62.19

Gene sequence:

>1161_bases
ATGAATTTCGCACTGACCGAAGAACAGCAGATGATCGTCGACACGGTCCGCAACTTTGTCGAAGCCGAGATTTATCCACA
CGAGAACGAGGTCGAGCGCACCGGCGTCGTGCCGCGCGACCTCGGGCAGGAAATTGCCCGCAAATGCAAGGAGCTTGGCT
TCTTTGGCTGCAATTTTCCGGAGGAGGTCGGCGGCGCAGGCCTTGACCATCTGACCTTCACGCTGGTCGAGCGCGAGCTC
GGCCGCGGATCAATGGGATTGACCGTTTTCTTCGGCCGCCCGTCAGGCATTCTGATGGCCTGCAACGAAGATCAGCGCGA
GCGCTACCTCCTGCCCGCCGTTCGTGGCGACAAGTTCGACGCGCTCGCCATGACCGAGCCGGACGCCGGCTCGGACGTAC
GCGGCATGAAATGCTTCGCCCGCCCGGATGGCGACGACTGGATCGTGAACGGAACGAAGCACTTCATCAGTCACGCCGAC
ATTGCCGATTTCGTCATCGTCTTCATCGCCACCGGCGAGGAGCAGACGCCGCGTGGACCGAAGAAAAAGATCACCTGCTT
CCTCGTCGACCGCGGCACGCCGGGCTTCGAGATCCGCGAGGGCTACAACTCGGTCTCGCATCGTGGATACAAGAACTGCA
TTCTGACTTTCGACGATTGTCGTCTGCCATCCGCCCAAATTCTAGGCGAGGTCCATAGAGGCTTCGATCTTGCCAATGAC
TGGCTTTACGCCACGCGCCTGACTGTTGCCGCCACCTCCGTCGGGCGCGCCCGCCGCGCCTTCGACTACGCGCTCTCCTA
TGCGGCGGAACGCAAACAGTTCGGCAAGCCGATCGGCGCCAACCAGGGTGTCTCCTTCAAGCTCGCGGACATGATAACAG
AGCTCGATGCCGCCGACCTCCTGACACTCTCGGCGGCGTGGCGGCTCGATCAGGGCCTGCCGGCCAATCGAGAGATTGCC
TCCGCAAAGGTTTATGCTACCGAAATGCTTGCCCGCGTCACCGACGAGGCGATCCAGATCTATGGCGGCATGGGGCTCAT
GGACGACCTGCCTCTCGCCCGCTTCTGGCGGGACGCGCGGGTCGAGCGCATCTGGGACGGGACGTCGGAGATCCAGCGAC
ACATCATCAGCCGCGACTTGTTGCGGCCGCTGGGAGCTTGA

Upstream 100 bases:

>100_bases
GCAGAAGCGGTAAGGATCGCATGCGGCAGCCCTCATCCGGCTGCCGCAGCCGCTTGCACCCATTTACCCCGGGGAGAGGG
GCAACTGACGAGGGAGAACC

Downstream 100 bases:

>100_bases
GGATGCGGCAGAGTCTTCGTTTCGGCAAGTTGCCCCGTTGCACAGCGGCTGCAGTCGAGCAGAACGGCGCGGCATATCCT
GCCTTGAGGGAGTGCATGGC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MNFALTEEQQMIVDTVRNFVEAEIYPHENEVERTGVVPRDLGQEIARKCKELGFFGCNFPEEVGGAGLDHLTFTLVEREL
GRGSMGLTVFFGRPSGILMACNEDQRERYLLPAVRGDKFDALAMTEPDAGSDVRGMKCFARPDGDDWIVNGTKHFISHAD
IADFVIVFIATGEEQTPRGPKKKITCFLVDRGTPGFEIREGYNSVSHRGYKNCILTFDDCRLPSAQILGEVHRGFDLAND
WLYATRLTVAATSVGRARRAFDYALSYAAERKQFGKPIGANQGVSFKLADMITELDAADLLTLSAAWRLDQGLPANREIA
SAKVYATEMLARVTDEAIQIYGGMGLMDDLPLARFWRDARVERIWDGTSEIQRHIISRDLLRPLGA

Sequences:

>Translated_386_residues
MNFALTEEQQMIVDTVRNFVEAEIYPHENEVERTGVVPRDLGQEIARKCKELGFFGCNFPEEVGGAGLDHLTFTLVEREL
GRGSMGLTVFFGRPSGILMACNEDQRERYLLPAVRGDKFDALAMTEPDAGSDVRGMKCFARPDGDDWIVNGTKHFISHAD
IADFVIVFIATGEEQTPRGPKKKITCFLVDRGTPGFEIREGYNSVSHRGYKNCILTFDDCRLPSAQILGEVHRGFDLAND
WLYATRLTVAATSVGRARRAFDYALSYAAERKQFGKPIGANQGVSFKLADMITELDAADLLTLSAAWRLDQGLPANREIA
SAKVYATEMLARVTDEAIQIYGGMGLMDDLPLARFWRDARVERIWDGTSEIQRHIISRDLLRPLGA
>Mature_386_residues
MNFALTEEQQMIVDTVRNFVEAEIYPHENEVERTGVVPRDLGQEIARKCKELGFFGCNFPEEVGGAGLDHLTFTLVEREL
GRGSMGLTVFFGRPSGILMACNEDQRERYLLPAVRGDKFDALAMTEPDAGSDVRGMKCFARPDGDDWIVNGTKHFISHAD
IADFVIVFIATGEEQTPRGPKKKITCFLVDRGTPGFEIREGYNSVSHRGYKNCILTFDDCRLPSAQILGEVHRGFDLAND
WLYATRLTVAATSVGRARRAFDYALSYAAERKQFGKPIGANQGVSFKLADMITELDAADLLTLSAAWRLDQGLPANREIA
SAKVYATEMLARVTDEAIQIYGGMGLMDDLPLARFWRDARVERIWDGTSEIQRHIISRDLLRPLGA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=383, Percent_Identity=37.0757180156658, Blast_Score=251, Evalue=6e-67,
Organism=Homo sapiens, GI226958412, Length=379, Percent_Identity=33.7730870712401, Blast_Score=224, Evalue=8e-59,
Organism=Homo sapiens, GI226958414, Length=341, Percent_Identity=34.8973607038123, Blast_Score=213, Evalue=4e-55,
Organism=Homo sapiens, GI4557231, Length=383, Percent_Identity=34.4647519582245, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI187960098, Length=383, Percent_Identity=34.4647519582245, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI4501859, Length=381, Percent_Identity=32.5459317585302, Blast_Score=208, Evalue=9e-54,
Organism=Homo sapiens, GI7656849, Length=396, Percent_Identity=32.8282828282828, Blast_Score=202, Evalue=5e-52,
Organism=Homo sapiens, GI4501857, Length=387, Percent_Identity=32.8165374677003, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI21361497, Length=364, Percent_Identity=31.043956043956, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI76496475, Length=390, Percent_Identity=31.7948717948718, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI4557235, Length=390, Percent_Identity=31.7948717948718, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI38505218, Length=404, Percent_Identity=28.960396039604, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI48976061, Length=411, Percent_Identity=26.7639902676399, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI211971008, Length=411, Percent_Identity=26.7639902676399, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI4503943, Length=386, Percent_Identity=26.1658031088083, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI7669494, Length=360, Percent_Identity=26.6666666666667, Blast_Score=106, Evalue=4e-23,
Organism=Escherichia coli, GI87081958, Length=388, Percent_Identity=32.9896907216495, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1786223, Length=388, Percent_Identity=29.8969072164948, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI87082384, Length=298, Percent_Identity=27.5167785234899, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538396, Length=383, Percent_Identity=33.6814621409922, Blast_Score=223, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI17570075, Length=390, Percent_Identity=33.8461538461538, Blast_Score=215, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI17534899, Length=387, Percent_Identity=34.1085271317829, Blast_Score=212, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI17569725, Length=386, Percent_Identity=32.6424870466321, Blast_Score=210, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17508101, Length=379, Percent_Identity=31.3984168865435, Blast_Score=203, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI17506239, Length=379, Percent_Identity=30.6068601583113, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17533517, Length=381, Percent_Identity=32.8083989501312, Blast_Score=192, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI71985184, Length=385, Percent_Identity=29.8701298701299, Blast_Score=164, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI71990804, Length=287, Percent_Identity=34.4947735191638, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17551932, Length=371, Percent_Identity=28.3018867924528, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17505929, Length=383, Percent_Identity=28.1984334203655, Blast_Score=140, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI71982178, Length=276, Percent_Identity=29.7101449275362, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI71985192, Length=320, Percent_Identity=27.8125, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17534353, Length=383, Percent_Identity=24.2819843342037, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17531909, Length=243, Percent_Identity=31.2757201646091, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI32563615, Length=226, Percent_Identity=30.5309734513274, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17562446, Length=360, Percent_Identity=27.7777777777778, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17531913, Length=162, Percent_Identity=29.0123456790123, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI86563381, Length=282, Percent_Identity=28.0141843971631, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI86563383, Length=282, Percent_Identity=28.0141843971631, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21356377, Length=384, Percent_Identity=34.1145833333333, Blast_Score=239, Evalue=2e-63,
Organism=Drosophila melanogaster, GI24646207, Length=386, Percent_Identity=34.9740932642487, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24660351, Length=390, Percent_Identity=35.3846153846154, Blast_Score=229, Evalue=3e-60,
Organism=Drosophila melanogaster, GI24666513, Length=379, Percent_Identity=31.3984168865435, Blast_Score=209, Evalue=3e-54,
Organism=Drosophila melanogaster, GI21355753, Length=383, Percent_Identity=33.6814621409922, Blast_Score=205, Evalue=3e-53,
Organism=Drosophila melanogaster, GI281363737, Length=336, Percent_Identity=32.7380952380952, Blast_Score=168, Evalue=6e-42,
Organism=Drosophila melanogaster, GI19920834, Length=385, Percent_Identity=29.3506493506493, Blast_Score=137, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 43054; Mature: 43054

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFALTEEQQMIVDTVRNFVEAEIYPHENEVERTGVVPRDLGQEIARKCKELGFFGCNFP
CCCCCCCHHHHHHHHHHHHHHEECCCCCCCHHHCCCCHHHHHHHHHHHHHHCCCCCCCCC
EEVGGAGLDHLTFTLVERELGRGSMGLTVFFGRPSGILMACNEDQRERYLLPAVRGDKFD
HHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEECCCCCCCEEECCCCCCCCCC
ALAMTEPDAGSDVRGMKCFARPDGDDWIVNGTKHFISHADIADFVIVFIATGEEQTPRGP
EEEECCCCCCCCCCCCEEEECCCCCCEEECCHHHHHHHCCHHHEEEEEEECCCCCCCCCC
KKKITCFLVDRGTPGFEIREGYNSVSHRGYKNCILTFDDCRLPSAQILGEVHRGFDLAND
CCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHCCCHHCC
WLYATRLTVAATSVGRARRAFDYALSYAAERKQFGKPIGANQGVSFKLADMITELDAADL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHCCHHHH
LTLSAAWRLDQGLPANREIASAKVYATEMLARVTDEAIQIYGGMGLMDDLPLARFWRDAR
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
VERIWDGTSEIQRHIISRDLLRPLGA
HHHHCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNFALTEEQQMIVDTVRNFVEAEIYPHENEVERTGVVPRDLGQEIARKCKELGFFGCNFP
CCCCCCCHHHHHHHHHHHHHHEECCCCCCCHHHCCCCHHHHHHHHHHHHHHCCCCCCCCC
EEVGGAGLDHLTFTLVERELGRGSMGLTVFFGRPSGILMACNEDQRERYLLPAVRGDKFD
HHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEECCCCCCCEEECCCCCCCCCC
ALAMTEPDAGSDVRGMKCFARPDGDDWIVNGTKHFISHADIADFVIVFIATGEEQTPRGP
EEEECCCCCCCCCCCCEEEECCCCCCEEECCHHHHHHHCCHHHEEEEEEECCCCCCCCCC
KKKITCFLVDRGTPGFEIREGYNSVSHRGYKNCILTFDDCRLPSAQILGEVHRGFDLAND
CCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHCCCHHCC
WLYATRLTVAATSVGRARRAFDYALSYAAERKQFGKPIGANQGVSFKLADMITELDAADL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHCCHHHH
LTLSAAWRLDQGLPANREIASAKVYATEMLARVTDEAIQIYGGMGLMDDLPLARFWRDAR
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
VERIWDGTSEIQRHIISRDLLRPLGA
HHHHCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]