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The map label for this gene is lsrR [H]

Identifier: 150397366

GI number: 150397366

Start: 2235539

End: 2236576

Strand: Reverse

Name: lsrR [H]

Synonym: Smed_2165

Alternate gene names: 150397366

Gene position: 2236576-2235539 (Counterclockwise)

Preceding gene: 150397367

Following gene: 150397365

Centisome position: 59.14

GC content: 62.81

Gene sequence:

>1038_bases
ATGAAAATTATTTCATATCGAGATAAAAATATCATGCGCTGCAAAAATTATCATGCGGCGCAGCATCGGGCGGGAGACAT
GGCGATCATCGGGGGAACAAGTGTCCGCGACGACGAGGCGAGCATGGCGACCCGTGCCGCCTGGCTGCACTACGCCGGCG
GGCTGACCCAGGCCGAGGTCGCCAAACGCCTGGGGCTCACATCGCTCAAGGCGCACCGGCTGATCATGAAAGCCAACCAG
GAAGGATTGGTGAAGGTCTATATCGACGGGGACGTCTCAGAATGCGTCGAGCTGGAGCAGAAGCTTTCCAGCCGTTACGG
TCTGGACTATTGCGAGGTGGTTCCCGATTTCGACAGCGAAGACCTGCCGCTGAAGGCGCTCGGCATCTCAGGCGCGCAGT
TTCTAAGGCGGGAGATCGAACGCGGAGAGACGGCGCTGATCGGGGTCGGCCACGGCAGAACGCTCGCAGCCAGCATTGAG
TACATGCCGCGCACGGCGAGCAACAACACGCGCTTCGTCTCCCTGCTCGGCGGCCTCACGCGCAAATTCTCCGCCAATCC
CCATGACGTGATCCACCGCCTGGCTGAGCGCACCGGCGCCGAGGCCTATGTCATGCCGGTGCCGTTCTTCGCCAACACGG
TTGAGGATCGGGACGTCCTCTTCAGCCAGCGGGGCGTGCGCGAAGTCTTCGATCTTGCGAAATCGGCCGACCTCCTGATG
GTCGGCATAGGCACCGCCGAACGCGAGGCCTCGCTGGTGGCGACCGGTATGATCGAGATGAGCGAGATAGAGCAGATCCA
GAAATGCGGCGGCACGGGTGAGCTGCTCGGGCACTTCTTCGACGAGAAGGGCAGGCCGATCGAAACGGCGCTTTCCAACC
GCACCTTCACGCTTGGTCGGGAGGACCTGAAGAACCGCCGCACCGTTGCGGTTGCCGGGGGCAGGATCAAGACCCGTGCC
ATTCGCGCGGTTCTCGGCAGCGGGTTCCTGAGCGGGCTCGTCACGGACGAGCGCACCGCACAGGCGCTCGCCGCGTAG

Upstream 100 bases:

>100_bases
ATCATCCCCGCCTTGCCGGGATCTTCCGCGAACGTATCCGTCGATGCGTCCGCGTTTTTTCGACATGCGGTCGATCGAGG
CTTGACAATTTTTTCAACCC

Downstream 100 bases:

>100_bases
AATTTCATGCGGGCCGCGATGCGACGAAAGTCGGCGTGCGGTCCGGTAGGCAATACCGGTTGGGTAGCCGGCAGCTCAGT
CGAGCAGTTTTACCCGTAGT

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MKIISYRDKNIMRCKNYHAAQHRAGDMAIIGGTSVRDDEASMATRAAWLHYAGGLTQAEVAKRLGLTSLKAHRLIMKANQ
EGLVKVYIDGDVSECVELEQKLSSRYGLDYCEVVPDFDSEDLPLKALGISGAQFLRREIERGETALIGVGHGRTLAASIE
YMPRTASNNTRFVSLLGGLTRKFSANPHDVIHRLAERTGAEAYVMPVPFFANTVEDRDVLFSQRGVREVFDLAKSADLLM
VGIGTAEREASLVATGMIEMSEIEQIQKCGGTGELLGHFFDEKGRPIETALSNRTFTLGREDLKNRRTVAVAGGRIKTRA
IRAVLGSGFLSGLVTDERTAQALAA

Sequences:

>Translated_345_residues
MKIISYRDKNIMRCKNYHAAQHRAGDMAIIGGTSVRDDEASMATRAAWLHYAGGLTQAEVAKRLGLTSLKAHRLIMKANQ
EGLVKVYIDGDVSECVELEQKLSSRYGLDYCEVVPDFDSEDLPLKALGISGAQFLRREIERGETALIGVGHGRTLAASIE
YMPRTASNNTRFVSLLGGLTRKFSANPHDVIHRLAERTGAEAYVMPVPFFANTVEDRDVLFSQRGVREVFDLAKSADLLM
VGIGTAEREASLVATGMIEMSEIEQIQKCGGTGELLGHFFDEKGRPIETALSNRTFTLGREDLKNRRTVAVAGGRIKTRA
IRAVLGSGFLSGLVTDERTAQALAA
>Mature_345_residues
MKIISYRDKNIMRCKNYHAAQHRAGDMAIIGGTSVRDDEASMATRAAWLHYAGGLTQAEVAKRLGLTSLKAHRLIMKANQ
EGLVKVYIDGDVSECVELEQKLSSRYGLDYCEVVPDFDSEDLPLKALGISGAQFLRREIERGETALIGVGHGRTLAASIE
YMPRTASNNTRFVSLLGGLTRKFSANPHDVIHRLAERTGAEAYVMPVPFFANTVEDRDVLFSQRGVREVFDLAKSADLLM
VGIGTAEREASLVATGMIEMSEIEQIQKCGGTGELLGHFFDEKGRPIETALSNRTFTLGREDLKNRRTVAVAGGRIKTRA
IRAVLGSGFLSGLVTDERTAQALAA

Specific function: Regulates transcription of many different genes. In the absence of autoinducer 2 (AI-2), represses transcription of the lsr operon and its own transcription. In the presence of AI-2, lsrR is inactivated by binding phospho-AI-2, leading to the transcriptio

COG id: COG2390

COG function: function code K; Transcriptional regulator, contains sigma factor-related N-terminal domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sorC transcriptional regulatory family [H]

Homologues:

Organism=Escherichia coli, GI1787791, Length=313, Percent_Identity=31.3099041533546, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI87082414, Length=320, Percent_Identity=23.4375, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04198 Sugar-bind [H]

EC number: NA

Molecular weight: Translated: 37721; Mature: 37721

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIISYRDKNIMRCKNYHAAQHRAGDMAIIGGTSVRDDEASMATRAAWLHYAGGLTQAEV
CCEECCCCCCHHHHHCCHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCCHHHH
AKRLGLTSLKAHRLIMKANQEGLVKVYIDGDVSECVELEQKLSSRYGLDYCEVVPDFDSE
HHHHCCHHHHHHHHHEECCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCC
DLPLKALGISGAQFLRREIERGETALIGVGHGRTLAASIEYMPRTASNNTRFVSLLGGLT
CCCEEEECCCHHHHHHHHHHCCCEEEEECCCCCEEEEEHHHCCCCCCCCCEEHHHHHHHH
RKFSANPHDVIHRLAERTGAEAYVMPVPFFANTVEDRDVLFSQRGVREVFDLAKSADLLM
HHCCCCHHHHHHHHHHHCCCCEEEEECCHHHCCCCHHHHHHHHCCHHHHHHHHCCCCEEE
VGIGTAEREASLVATGMIEMSEIEQIQKCGGTGELLGHFFDEKGRPIETALSNRTFTLGR
EECCCCCHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHCCCEEEECH
EDLKNRRTVAVAGGRIKTRAIRAVLGSGFLSGLVTDERTAQALAA
HHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC
>Mature Secondary Structure
MKIISYRDKNIMRCKNYHAAQHRAGDMAIIGGTSVRDDEASMATRAAWLHYAGGLTQAEV
CCEECCCCCCHHHHHCCHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCCHHHH
AKRLGLTSLKAHRLIMKANQEGLVKVYIDGDVSECVELEQKLSSRYGLDYCEVVPDFDSE
HHHHCCHHHHHHHHHEECCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCC
DLPLKALGISGAQFLRREIERGETALIGVGHGRTLAASIEYMPRTASNNTRFVSLLGGLT
CCCEEEECCCHHHHHHHHHHCCCEEEEECCCCCEEEEEHHHCCCCCCCCCEEHHHHHHHH
RKFSANPHDVIHRLAERTGAEAYVMPVPFFANTVEDRDVLFSQRGVREVFDLAKSADLLM
HHCCCCHHHHHHHHHHHCCCCEEEEECCHHHCCCCHHHHHHHHCCHHHHHHHHCCCCEEE
VGIGTAEREASLVATGMIEMSEIEQIQKCGGTGELLGHFFDEKGRPIETALSNRTFTLGR
EECCCCCHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHCCCEEEECH
EDLKNRRTVAVAGGRIKTRAIRAVLGSGFLSGLVTDERTAQALAA
HHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA