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The map label for this gene is glpD [H]

Identifier: 150397357

GI number: 150397357

Start: 2224913

End: 2226466

Strand: Reverse

Name: glpD [H]

Synonym: Smed_2156

Alternate gene names: 150397357

Gene position: 2226466-2224913 (Counterclockwise)

Preceding gene: 150397358

Following gene: 150397356

Centisome position: 58.87

GC content: 63.0

Gene sequence:

>1554_bases
ATGACGTCGACAGGAGACAAACACGTGAGTTCCGAAACCGGCACATACGACCTTTTCGTCATTGGCGGCGGCATCAACGG
GGCAGGCATTGCCCGAGACGCGGCGGGGCGCGGGCTTTCCGTCCTGCTTTGCGAAAAGGAAGATCTGGCACAGGGCACGA
GTTCCCGCTCCGGCAAGCTCGTCCACGGCGGCTTACGCTATCTCGAATATTACGAGTTCCGCCTGGTGCGCGAGGCGCTG
ATCGAGCGGGAGGTGCTGCTGGAGTCGGCACCTCATATCATCTGGCCGATGCGTTTCGTGCTGCCGCACAATCCGACCGA
CCGGCCCGCCTGGCTCGTGCGCCTCGGCCTGTTTCTCTATGATCATCTGGGTGGGCGCAAACGCCTTCCCGGTACGCGGA
TGCTCAACCTGCGCACGGCGCCGGAAGGTGCTCCGATCAAGCCGGCCTATCGCAAAGCCTTCGAATATTCGGACTGTTGG
GTAGACGACGCCCGTCTGGTCGTGTTGAACGCGCTCGACGCGAAAAACAAAGGCGCGCGGGTCCTGACCCGTACCGCCTG
CACCAGCGTTCGCCGGCGCGGCGAACTCTGGCATGTCGAGATGACCGATGCGGAGACCGGGGCCAGGACCGAAGCCAAAG
CGCGTTGCGTGGTCAACACTGCCGGGCCCTGGGTCAACGACGTGATCGGCCGGGTCGCAGGACTGAATTCGAGCCGCAGC
GTTCGCCTCGTCAAGGGCAGCCATATCGTCGTGCCGAAGTTCTGGGAGGGGCGTCAGGCCTATCTGGTCCAGAATCCCGA
CAAGCGCGTGATCTTCATCAATCCGTACCAGAACGACCTGGCGCTGATCGGCACCACCGATATTCCCTATGAGGGGCGGC
CGGAGGACGTGTCCGCCGACGATAGCGAGATTGATTATCTCCTGACGTCCGTGAACCGCTATTTCAAGCAGCAAATGACG
CCGCGCGACATCCTTCACAGCTTCTCCGGTGTTCGGCCGCTTTACGACGACAATGCCGAAAATCCGTCGGCAGTGACGCG
CGACTACATTTTCGAGCTCGATGCCCCGCAAAAGGGCGCCGCCGGGAGGGAAGCGCCGCTGCTCTCGGTATTTGGCGGCA
AGATCACGACCTTCCGCAAGCTGTCCGAACACGCCTTGGAGCGACTGAAGCCCTTCTTTCCCGAGATGGGGCCGGCTTGG
ACGGCGCGCTCGCACCTGCCGGGAGGCGATATGGCGGAAGCGGATTTCGACCAGTTCCTCGGCGAGCTGCGCACACGCCA
CCAGTGGTTGCCGGCGGATCTCGCCAAGCATTATGCAAGGCTGTACGGCACGCGCGCCGATGAGCTGATCGGCAGCGCTG
CCTCGCTCGAGGAGCTCGGCACTGCGTTCACCCCCCTCTTCAGGGAACGGGAAGCCCGCTTCCTCATCGAAAATGAATGG
GTGCGCACGGCGGAAGACCTGATCGAACGCCGTACGAAGCACGGCCTGCATATGAGCGAAACGGAGAAGCGGGCGTTCAG
CGGCTGGTTCCAGGGTCAGCAGGCGGCGGCGTGA

Upstream 100 bases:

>100_bases
GGCCCGGTGATCCTGCCGCAGCAGGAAATCGACGGCGTGCTCGAGGGATTTGCCACCTACGGCCACCAGGACAAGCCGAA
GGGCGAGGCCGCCTGACCGC

Downstream 100 bases:

>100_bases
AAAGGAAGAATTGATGTTGCAAAGCCCCGAATTCGAAGCGCTTCTCGATCTCTCCGCCCGCGTCGGCGCGGATACGGACC
TCGTTCAGGGGGCAGGCGGC

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 517; Mature: 516

Protein sequence:

>517_residues
MTSTGDKHVSSETGTYDLFVIGGGINGAGIARDAAGRGLSVLLCEKEDLAQGTSSRSGKLVHGGLRYLEYYEFRLVREAL
IEREVLLESAPHIIWPMRFVLPHNPTDRPAWLVRLGLFLYDHLGGRKRLPGTRMLNLRTAPEGAPIKPAYRKAFEYSDCW
VDDARLVVLNALDAKNKGARVLTRTACTSVRRRGELWHVEMTDAETGARTEAKARCVVNTAGPWVNDVIGRVAGLNSSRS
VRLVKGSHIVVPKFWEGRQAYLVQNPDKRVIFINPYQNDLALIGTTDIPYEGRPEDVSADDSEIDYLLTSVNRYFKQQMT
PRDILHSFSGVRPLYDDNAENPSAVTRDYIFELDAPQKGAAGREAPLLSVFGGKITTFRKLSEHALERLKPFFPEMGPAW
TARSHLPGGDMAEADFDQFLGELRTRHQWLPADLAKHYARLYGTRADELIGSAASLEELGTAFTPLFREREARFLIENEW
VRTAEDLIERRTKHGLHMSETEKRAFSGWFQGQQAAA

Sequences:

>Translated_517_residues
MTSTGDKHVSSETGTYDLFVIGGGINGAGIARDAAGRGLSVLLCEKEDLAQGTSSRSGKLVHGGLRYLEYYEFRLVREAL
IEREVLLESAPHIIWPMRFVLPHNPTDRPAWLVRLGLFLYDHLGGRKRLPGTRMLNLRTAPEGAPIKPAYRKAFEYSDCW
VDDARLVVLNALDAKNKGARVLTRTACTSVRRRGELWHVEMTDAETGARTEAKARCVVNTAGPWVNDVIGRVAGLNSSRS
VRLVKGSHIVVPKFWEGRQAYLVQNPDKRVIFINPYQNDLALIGTTDIPYEGRPEDVSADDSEIDYLLTSVNRYFKQQMT
PRDILHSFSGVRPLYDDNAENPSAVTRDYIFELDAPQKGAAGREAPLLSVFGGKITTFRKLSEHALERLKPFFPEMGPAW
TARSHLPGGDMAEADFDQFLGELRTRHQWLPADLAKHYARLYGTRADELIGSAASLEELGTAFTPLFREREARFLIENEW
VRTAEDLIERRTKHGLHMSETEKRAFSGWFQGQQAAA
>Mature_516_residues
TSTGDKHVSSETGTYDLFVIGGGINGAGIARDAAGRGLSVLLCEKEDLAQGTSSRSGKLVHGGLRYLEYYEFRLVREALI
EREVLLESAPHIIWPMRFVLPHNPTDRPAWLVRLGLFLYDHLGGRKRLPGTRMLNLRTAPEGAPIKPAYRKAFEYSDCWV
DDARLVVLNALDAKNKGARVLTRTACTSVRRRGELWHVEMTDAETGARTEAKARCVVNTAGPWVNDVIGRVAGLNSSRSV
RLVKGSHIVVPKFWEGRQAYLVQNPDKRVIFINPYQNDLALIGTTDIPYEGRPEDVSADDSEIDYLLTSVNRYFKQQMTP
RDILHSFSGVRPLYDDNAENPSAVTRDYIFELDAPQKGAAGREAPLLSVFGGKITTFRKLSEHALERLKPFFPEMGPAWT
ARSHLPGGDMAEADFDQFLGELRTRHQWLPADLAKHYARLYGTRADELIGSAASLEELGTAFTPLFREREARFLIENEWV
RTAEDLIERRTKHGLHMSETEKRAFSGWFQGQQAAA

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=510, Percent_Identity=30.3921568627451, Blast_Score=196, Evalue=4e-50,
Organism=Homo sapiens, GI285002231, Length=510, Percent_Identity=30.3921568627451, Blast_Score=196, Evalue=4e-50,
Organism=Escherichia coli, GI2367226, Length=472, Percent_Identity=50.4237288135593, Blast_Score=482, Evalue=1e-137,
Organism=Escherichia coli, GI1788574, Length=482, Percent_Identity=26.5560165975104, Blast_Score=101, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI115534726, Length=510, Percent_Identity=28.8235294117647, Blast_Score=165, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI17509253, Length=512, Percent_Identity=29.4921875, Blast_Score=158, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6322036, Length=561, Percent_Identity=27.807486631016, Blast_Score=167, Evalue=5e-42,
Organism=Drosophila melanogaster, GI161077125, Length=510, Percent_Identity=31.1764705882353, Blast_Score=183, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24653942, Length=510, Percent_Identity=31.1764705882353, Blast_Score=183, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24653944, Length=510, Percent_Identity=31.1764705882353, Blast_Score=183, Evalue=3e-46,
Organism=Drosophila melanogaster, GI20130025, Length=510, Percent_Identity=31.1764705882353, Blast_Score=183, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24586295, Length=510, Percent_Identity=27.6470588235294, Blast_Score=125, Evalue=7e-29,
Organism=Drosophila melanogaster, GI19921278, Length=504, Percent_Identity=23.015873015873, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 57996; Mature: 57865

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: PS00977 FAD_G3PDH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSTGDKHVSSETGTYDLFVIGGGINGAGIARDAAGRGLSVLLCEKEDLAQGTSSRSGKL
CCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHCCCCCCEEEEECCHHHHCCCCCCCCCE
VHGGLRYLEYYEFRLVREALIEREVLLESAPHIIWPMRFVLPHNPTDRPAWLVRLGLFLY
EEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECEEEEECCCCCCCHHHHHHHHHHHH
DHLGGRKRLPGTRMLNLRTAPEGAPIKPAYRKAFEYSDCWVDDARLVVLNALDAKNKGAR
HHCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCH
VLTRTACTSVRRRGELWHVEMTDAETGARTEAKARCVVNTAGPWVNDVIGRVAGLNSSRS
HHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCC
VRLVKGSHIVVPKFWEGRQAYLVQNPDKRVIFINPYQNDLALIGTTDIPYEGRPEDVSAD
EEEEECCEEEEECCCCCCEEEEEECCCCEEEEECCCCCCEEEEECCCCCCCCCCCCCCCC
DSEIDYLLTSVNRYFKQQMTPRDILHSFSGVRPLYDDNAENPSAVTRDYIFELDAPQKGA
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHEEEECCCCCCC
AGREAPLLSVFGGKITTFRKLSEHALERLKPFFPEMGPAWTARSHLPGGDMAEADFDQFL
CCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHH
GELRTRHQWLPADLAKHYARLYGTRADELIGSAASLEELGTAFTPLFREREARFLIENEW
HHHHHHCCCCCHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEHHHH
VRTAEDLIERRTKHGLHMSETEKRAFSGWFQGQQAAA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TSTGDKHVSSETGTYDLFVIGGGINGAGIARDAAGRGLSVLLCEKEDLAQGTSSRSGKL
CCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHCCCCCCEEEEECCHHHHCCCCCCCCCE
VHGGLRYLEYYEFRLVREALIEREVLLESAPHIIWPMRFVLPHNPTDRPAWLVRLGLFLY
EEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECEEEEECCCCCCCHHHHHHHHHHHH
DHLGGRKRLPGTRMLNLRTAPEGAPIKPAYRKAFEYSDCWVDDARLVVLNALDAKNKGAR
HHCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCH
VLTRTACTSVRRRGELWHVEMTDAETGARTEAKARCVVNTAGPWVNDVIGRVAGLNSSRS
HHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCC
VRLVKGSHIVVPKFWEGRQAYLVQNPDKRVIFINPYQNDLALIGTTDIPYEGRPEDVSAD
EEEEECCEEEEECCCCCCEEEEEECCCCEEEEECCCCCCEEEEECCCCCCCCCCCCCCCC
DSEIDYLLTSVNRYFKQQMTPRDILHSFSGVRPLYDDNAENPSAVTRDYIFELDAPQKGA
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHEEEECCCCCCC
AGREAPLLSVFGGKITTFRKLSEHALERLKPFFPEMGPAWTARSHLPGGDMAEADFDQFL
CCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHH
GELRTRHQWLPADLAKHYARLYGTRADELIGSAASLEELGTAFTPLFREREARFLIENEW
HHHHHHCCCCCHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEHHHH
VRTAEDLIERRTKHGLHMSETEKRAFSGWFQGQQAAA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157588; 10984043 [H]