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The map label for this gene is fucA [H]

Identifier: 150397358

GI number: 150397358

Start: 2226471

End: 2227139

Strand: Reverse

Name: fucA [H]

Synonym: Smed_2157

Alternate gene names: 150397358

Gene position: 2227139-2226471 (Counterclockwise)

Preceding gene: 150397359

Following gene: 150397357

Centisome position: 58.89

GC content: 62.48

Gene sequence:

>669_bases
ATGAACGAACTTCAACTGCGCCAGTCGATCATCGATCATTGCCGCCACATGAATGCGATCGGTCTGAACCAGGGCACGTC
GGGTAATATCAGCCTTCGGCATGGTGACACGATGCTGATCACGCCCTCCGCAGTCCCCTATGCCGAGATGACGCCGGAGA
TGATCGTCGCGATGCCGGTCGAGGGCGAGTATGGCGTCTGGTCAGGGCCGAAAAGGCCGTCTGTCGAATGGCCCTTCCAT
CTGGATATTCTGCGCGCCCGGCCGGATGTCGGCGCGGTGGTCCACACCCATGCGACCTTCTCGACGATCCTTTCGATCGC
TCGCAAGCCCATTCCGGCCTGCCACTACATGATCGCCGCCTTTGGCGGCTCGGATGTGCGCGTCGCCGACTATGCGCGCT
ACGGCACGAAGGCGCTTTCCGAAAAGGTGCTGAAGGCGATGGAGGGACGTTCCGCCTGCCTCATGGCCAATCACGGCATG
ATCGCGACGGGGTCGAGCCTGGAAAAGGCGATGTGGGCGGCGGTCGAACTCGAGACGATCGCCAAGCAATATTACCACGC
GCTCCTGATCGGCGGCCCGGTGATCCTGCCGCAGCAGGAAATCGACGGCGTGCTCGAGGGATTTGCCACCTACGGCCACC
AGGACAAGCCGAAGGGCGAGGCCGCCTGA

Upstream 100 bases:

>100_bases
GTCGGTGCGTACCGTGACCTATGCGGCTGAAATGGCCGCAGAGGAAGTGCGCCGCTATATCGCCGGTCTGCCGCCGGTCA
ATCCGTGCTGAGGTGGGACG

Downstream 100 bases:

>100_bases
CCGCATGACGTCGACAGGAGACAAACACGTGAGTTCCGAAACCGGCACATACGACCTTTTCGTCATTGGCGGCGGCATCA
ACGGGGCAGGCATTGCCCGA

Product: class II aldolase/adducin family protein

Products: NA

Alternate protein names: L-fuculose-1-phosphate aldolase [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MNELQLRQSIIDHCRHMNAIGLNQGTSGNISLRHGDTMLITPSAVPYAEMTPEMIVAMPVEGEYGVWSGPKRPSVEWPFH
LDILRARPDVGAVVHTHATFSTILSIARKPIPACHYMIAAFGGSDVRVADYARYGTKALSEKVLKAMEGRSACLMANHGM
IATGSSLEKAMWAAVELETIAKQYYHALLIGGPVILPQQEIDGVLEGFATYGHQDKPKGEAA

Sequences:

>Translated_222_residues
MNELQLRQSIIDHCRHMNAIGLNQGTSGNISLRHGDTMLITPSAVPYAEMTPEMIVAMPVEGEYGVWSGPKRPSVEWPFH
LDILRARPDVGAVVHTHATFSTILSIARKPIPACHYMIAAFGGSDVRVADYARYGTKALSEKVLKAMEGRSACLMANHGM
IATGSSLEKAMWAAVELETIAKQYYHALLIGGPVILPQQEIDGVLEGFATYGHQDKPKGEAA
>Mature_222_residues
MNELQLRQSIIDHCRHMNAIGLNQGTSGNISLRHGDTMLITPSAVPYAEMTPEMIVAMPVEGEYGVWSGPKRPSVEWPFH
LDILRARPDVGAVVHTHATFSTILSIARKPIPACHYMIAAFGGSDVRVADYARYGTKALSEKVLKAMEGRSACLMANHGM
IATGSSLEKAMWAAVELETIAKQYYHALLIGGPVILPQQEIDGVLEGFATYGHQDKPKGEAA

Specific function: Fucose metabolism; third step. [C]

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. AraD/FucA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789164, Length=213, Percent_Identity=46.9483568075117, Blast_Score=190, Evalue=8e-50,
Organism=Escherichia coli, GI1789094, Length=190, Percent_Identity=30.5263157894737, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303
- InterPro:   IPR004782 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: =4.1.2.17 [H]

Molecular weight: Translated: 24124; Mature: 24124

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNELQLRQSIIDHCRHMNAIGLNQGTSGNISLRHGDTMLITPSAVPYAEMTPEMIVAMPV
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCEEEECCCCCCHHHCCCCEEEEEEC
EGEYGVWSGPKRPSVEWPFHLDILRARPDVGAVVHTHATFSTILSIARKPIPACHYMIAA
CCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEECHHHHHHHHHHHHCCCCHHHHHHHH
FGGSDVRVADYARYGTKALSEKVLKAMEGRSACLMANHGMIATGSSLEKAMWAAVELETI
CCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEECCHHHHHHHHHHHHHHH
AKQYYHALLIGGPVILPQQEIDGVLEGFATYGHQDKPKGEAA
HHHHHHHHHCCCCEECCHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNELQLRQSIIDHCRHMNAIGLNQGTSGNISLRHGDTMLITPSAVPYAEMTPEMIVAMPV
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCEEEECCCCCCHHHCCCCEEEEEEC
EGEYGVWSGPKRPSVEWPFHLDILRARPDVGAVVHTHATFSTILSIARKPIPACHYMIAA
CCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEECHHHHHHHHHHHHCCCCHHHHHHHH
FGGSDVRVADYARYGTKALSEKVLKAMEGRSACLMANHGMIATGSSLEKAMWAAVELETI
CCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEECCHHHHHHHHHHHHHHH
AKQYYHALLIGGPVILPQQEIDGVLEGFATYGHQDKPKGEAA
HHHHHHHHHCCCCEECCHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]