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The map label for this gene is sdsB [H]

Identifier: 150397270

GI number: 150397270

Start: 2121042

End: 2122022

Strand: Direct

Name: sdsB [H]

Synonym: Smed_2069

Alternate gene names: 150397270

Gene position: 2121042-2122022 (Clockwise)

Preceding gene: 150397268

Following gene: 150397280

Centisome position: 56.08

GC content: 56.88

Gene sequence:

>981_bases
ATGCTAAAATTCCTTTTCTGCGAGAATCGATACGGATTTGTTATGGACCTCTTTAGGCATGTCGGCCTTCTGCGCTCATT
TTTGATGGTCGCGCGGGAGGGGAATGTGACGGCGGCGGCTGAAAAACTCGGCATCAGTCAGCCCGCGCTGACGCGGAGCA
TTCGCCGCCTGGAAGACGAAACGGGCTTTCGCCTTTTTGATCGGCATACGAGAGGGGTCACACCCACGATCTATGGGAAG
GCGCTGCTCCGCCACGCCCAGTTGATCGATACGGAATGCCGCTTCGCATCTTCAGAACTGGAGGCCCTTCGTTCCGGGCA
TAGAGGGCAGATAAAAATCGGAGGCGGCCCTTTCTGGGGTGCCGCCCTGCTGCCGAGGGCTGTCGCGCGATTGCATTCGC
TTCTGCCCAAGCTACAGGTGAACTTGCAGATCGGCGTCAACAACGTGCTTCATCCGAAACTGCTGGATGGAGAACTGGAC
CTGGTGGTATCTGCAGCCCCCCGCGATCTATCGCAATTTCCGGAGCATTTCCGCTTTACTCGGATCACGACCATACGGAG
CCAGATGTTTGTCCGTGAAGGGCACCCCATTCTCGCACAAGAACGGATCCGCTACGAGGATTTGGCAAATTATCCATGGA
TCATGTATCAGCAGGATCCGGAGATAATCGAGCGGGTCGCGACACTCCTCAAAGACCTCGGGGTCAACCCGCCTCGGATC
GCCATCAAGGCAAGCTCACTGATGGCCGTATTGGAGCTTCTCAGATCAGGAGACTTCTTGGCCTGTTTGGCGGCGCCCAT
CCTTGGCGTCGTCCAGGACGTCGGAATCCGCCCCGTCCCCATCGACCGCGAAATTTGGAGCTTCCCCGCTGGCATTACTT
ACCATCGTGCAATCGAGCAATCCACGCCGTTTGAGCTGCTCAGACAGATGTTGACCGACGAGGTCACGAAACTCGGGCTC
GACCGGACCGAACAAAGATAA

Upstream 100 bases:

>100_bases
CGGCAGTGCGGTTCAGTGAATCGAACAATACAAATATGGCTCGCAACCGCGTCAAGCTCCTCTTCAAGTTCCCAATTCAA
ATGTACCGTGCTGGCGCCAT

Downstream 100 bases:

>100_bases
TTCAGACACCAGCTAAATCGAATCGAGGGGAAGACCGCACATAGTGAGTTGCGCTACCCGCCGATCAGCGCCAACCACTC
GTCCTCGTCCATCGTCTGGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MLKFLFCENRYGFVMDLFRHVGLLRSFLMVAREGNVTAAAEKLGISQPALTRSIRRLEDETGFRLFDRHTRGVTPTIYGK
ALLRHAQLIDTECRFASSELEALRSGHRGQIKIGGGPFWGAALLPRAVARLHSLLPKLQVNLQIGVNNVLHPKLLDGELD
LVVSAAPRDLSQFPEHFRFTRITTIRSQMFVREGHPILAQERIRYEDLANYPWIMYQQDPEIIERVATLLKDLGVNPPRI
AIKASSLMAVLELLRSGDFLACLAAPILGVVQDVGIRPVPIDREIWSFPAGITYHRAIEQSTPFELLRQMLTDEVTKLGL
DRTEQR

Sequences:

>Translated_326_residues
MLKFLFCENRYGFVMDLFRHVGLLRSFLMVAREGNVTAAAEKLGISQPALTRSIRRLEDETGFRLFDRHTRGVTPTIYGK
ALLRHAQLIDTECRFASSELEALRSGHRGQIKIGGGPFWGAALLPRAVARLHSLLPKLQVNLQIGVNNVLHPKLLDGELD
LVVSAAPRDLSQFPEHFRFTRITTIRSQMFVREGHPILAQERIRYEDLANYPWIMYQQDPEIIERVATLLKDLGVNPPRI
AIKASSLMAVLELLRSGDFLACLAAPILGVVQDVGIRPVPIDREIWSFPAGITYHRAIEQSTPFELLRQMLTDEVTKLGL
DRTEQR
>Mature_326_residues
MLKFLFCENRYGFVMDLFRHVGLLRSFLMVAREGNVTAAAEKLGISQPALTRSIRRLEDETGFRLFDRHTRGVTPTIYGK
ALLRHAQLIDTECRFASSELEALRSGHRGQIKIGGGPFWGAALLPRAVARLHSLLPKLQVNLQIGVNNVLHPKLLDGELD
LVVSAAPRDLSQFPEHFRFTRITTIRSQMFVREGHPILAQERIRYEDLANYPWIMYQQDPEIIERVATLLKDLGVNPPRI
AIKASSLMAVLELLRSGDFLACLAAPILGVVQDVGIRPVPIDREIWSFPAGITYHRAIEQSTPFELLRQMLTDEVTKLGL
DRTEQR

Specific function: Activates the transcription of the sdsA gene for sodium dodecyl sulfate (SDS) degradation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=243, Percent_Identity=30.4526748971193, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI157672245, Length=265, Percent_Identity=26.4150943396226, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI145693105, Length=192, Percent_Identity=27.6041666666667, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1789506, Length=237, Percent_Identity=23.6286919831224, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI87081904, Length=307, Percent_Identity=23.7785016286645, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788297, Length=141, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790399, Length=264, Percent_Identity=26.8939393939394, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1790262, Length=239, Percent_Identity=25.9414225941423, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI2367136, Length=100, Percent_Identity=37, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788748, Length=147, Percent_Identity=29.2517006802721, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 36895; Mature: 36895

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKFLFCENRYGFVMDLFRHVGLLRSFLMVAREGNVTAAAEKLGISQPALTRSIRRLEDE
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHH
TGFRLFDRHTRGVTPTIYGKALLRHAQLIDTECRFASSELEALRSGHRGQIKIGGGPFWG
CCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHH
AALLPRAVARLHSLLPKLQVNLQIGVNNVLHPKLLDGELDLVVSAAPRDLSQFPEHFRFT
HHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCEECCCEEEEEECCCHHHHHHHHHHHHH
RITTIRSQMFVREGHPILAQERIRYEDLANYPWIMYQQDPEIIERVATLLKDLGVNPPRI
HHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCCEE
AIKASSLMAVLELLRSGDFLACLAAPILGVVQDVGIRPVPIDREIWSFPAGITYHRAIEQ
EEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCHHHHHHHC
STPFELLRQMLTDEVTKLGLDRTEQR
CCHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLKFLFCENRYGFVMDLFRHVGLLRSFLMVAREGNVTAAAEKLGISQPALTRSIRRLEDE
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHH
TGFRLFDRHTRGVTPTIYGKALLRHAQLIDTECRFASSELEALRSGHRGQIKIGGGPFWG
CCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHH
AALLPRAVARLHSLLPKLQVNLQIGVNNVLHPKLLDGELDLVVSAAPRDLSQFPEHFRFT
HHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCEECCCEEEEEECCCHHHHHHHHHHHHH
RITTIRSQMFVREGHPILAQERIRYEDLANYPWIMYQQDPEIIERVATLLKDLGVNPPRI
HHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCCEE
AIKASSLMAVLELLRSGDFLACLAAPILGVVQDVGIRPVPIDREIWSFPAGITYHRAIEQ
EEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCHHHHHHHC
STPFELLRQMLTDEVTKLGLDRTEQR
CCHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1587481 [H]