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The map label for this gene is yciA [H]

Identifier: 150396823

GI number: 150396823

Start: 1709504

End: 1709893

Strand: Direct

Name: yciA [H]

Synonym: Smed_1614

Alternate gene names: 150396823

Gene position: 1709504-1709893 (Clockwise)

Preceding gene: 150396815

Following gene: 150396824

Centisome position: 45.2

GC content: 63.85

Gene sequence:

>390_bases
ATGACCGCAGCGAACAAGCCGAACGGCGAACTGACCTTGCGCACGCTCGCAATGCCCGGGGACGCCAATGCCGCCGGCGA
CATCTTCGGCGGCTGGGTCATGGCGCAGATGGACCTTTCCTGCGGCATACGGGCCGCCGAACGCGCCAGGGGGCGCGTGG
TGACTGCGGCCGTGAAGGAAATGGCCTTTGCGTTGCCGGTGAAGATCGGCGACACGCTCTGCATCTATACCGATATCATC
AAGGTCGGCCGGACGTCGATGACGCTGAAGGTCGAGGCTTGGGCACAGCGTTACCTCTCGCAGGTCATGGACAAGGTCAC
GGATGCGATCTTCGTGATGGTCGCGCTCGACTCGTCCGGCAAGCCGACGCCGGTTCCTGCCGAGGAATAG

Upstream 100 bases:

>100_bases
GCCCTGCCTTCACGTTTCAGCGTGGAATTGTTCCGAGTGCCCTTTGCTCGCGCCGGAGCGGTGCGCTAAAGCTTTTGTCG
CAACAGGGAGACAGGGCCGA

Downstream 100 bases:

>100_bases
GGGCCGAGTGCATGGAGCACGTACAGCCCGATCCAGCGATCTTTTCTCATATTCGCGTCGTCATGGGCATGGTGATCAGC
CTGTCGCTCGCGCGGCTCCT

Product: thioesterase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 129; Mature: 128

Protein sequence:

>129_residues
MTAANKPNGELTLRTLAMPGDANAAGDIFGGWVMAQMDLSCGIRAAERARGRVVTAAVKEMAFALPVKIGDTLCIYTDII
KVGRTSMTLKVEAWAQRYLSQVMDKVTDAIFVMVALDSSGKPTPVPAEE

Sequences:

>Translated_129_residues
MTAANKPNGELTLRTLAMPGDANAAGDIFGGWVMAQMDLSCGIRAAERARGRVVTAAVKEMAFALPVKIGDTLCIYTDII
KVGRTSMTLKVEAWAQRYLSQVMDKVTDAIFVMVALDSSGKPTPVPAEE
>Mature_128_residues
TAANKPNGELTLRTLAMPGDANAAGDIFGGWVMAQMDLSCGIRAAERARGRVVTAAVKEMAFALPVKIGDTLCIYTDIIK
VGRTSMTLKVEAWAQRYLSQVMDKVTDAIFVMVALDSSGKPTPVPAEE

Specific function: Catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA [H]

COG id: COG1607

COG function: function code I; Acyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl coenzyme A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1787506, Length=130, Percent_Identity=47.6923076923077, Blast_Score=127, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006683 [H]

Pfam domain/function: PF03061 4HBT [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 13777; Mature: 13646

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAANKPNGELTLRTLAMPGDANAAGDIFGGWVMAQMDLSCGIRAAERARGRVVTAAVKE
CCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHEEEECCCCCCCHHHHHCCCCHHHHHHH
MAFALPVKIGDTLCIYTDIIKVGRTSMTLKVEAWAQRYLSQVMDKVTDAIFVMVALDSSG
HHHHCCCCCCCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHEEEEEEECCCC
KPTPVPAEE
CCCCCCCCC
>Mature Secondary Structure 
TAANKPNGELTLRTLAMPGDANAAGDIFGGWVMAQMDLSCGIRAAERARGRVVTAAVKE
CCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHEEEECCCCCCCHHHHHCCCCHHHHHHH
MAFALPVKIGDTLCIYTDIIKVGRTSMTLKVEAWAQRYLSQVMDKVTDAIFVMVALDSSG
HHHHCCCCCCCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHEEEEEEECCCC
KPTPVPAEE
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]