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The map label for this gene is csd [H]

Identifier: 150396431

GI number: 150396431

Start: 1296732

End: 1297913

Strand: Direct

Name: csd [H]

Synonym: Smed_1213

Alternate gene names: 150396431

Gene position: 1296732-1297913 (Clockwise)

Preceding gene: 150396430

Following gene: 150396432

Centisome position: 34.29

GC content: 58.8

Gene sequence:

>1182_bases
ATGCCTATAGACCTCGAAAAGGTTAGATCAGAGACACCGGGTATCCGGAACCGAATCCACCTGAACAACGCTGGGGCAGC
TCTGATGCCGAATCCGGTGCTCGAAGCCATGGTTGGCTATCTCAACCGGGAAGCGGAGGTTGGTGGGTACGAGGCGGCCG
GTGAAGCTGCTAGTGAGCTTGATGGCGTCTACGATAGCGTGGCGCGCCTGCTTGGTTGCGGTCGGGATGAGATCGCCCTG
ACCGAAAATGCGACCGTCGCCTGGCAGCTCGCCTTCTATGCCCTCACGTTTCGGCCCGGAGACCGCATACTCACGGCGCG
GGCCGAATATGCAGCAAACTACGTCGCCTTTCTGCAGATCGCGAAGCGCACCGGGGCGTCGATAGAAGTCATTCCGAGCG
ATGACGGCGGCGTCCTTGACCCGGCATGCCTTGAACAGATGCTCGACGAACGCGTGAAGCTCATCGCCATTACCTGGGTG
CCAACGAACGGAGGGCTGCGCAATCCCGCGGCTGCCGTGGGTGCGATTGCACGTCGCCACGGTATAACTTATCTGCTCGA
CGCGTGCCAAGCTGTCGGACAGATGCCGACACGCGTCGAAGAGCTTGGCTGCGATATATTGACGGGAACAGGTCGCAAAT
TTCTTCGCGGCCCACGCGGAACCGGATTTCTCTATATCCGCAGAGAGCTCTTACTGACCCTGGAACCACCAATGATCGAT
CACTTCGCGGCCCCGTGGGTCGCTCCAGATCGCTATGAGCTACGGCGTGACGCGCGGCGGTTCGAGACGTGGGAGAACAA
CTACGCCGCTCGTCTGGGTCTCGGCCGCGCTTTGGATTACGCGCTGGATCTGGGACTGCACGAAATTGAGAATCGATGCG
GCAACTTATCGGAGAGATTGCGCAATGGACTTCGGAACATCGAGGGGGTCGCCGTCCATGATCTCGGGCCGAAGCCAGCG
TCAATTGTGACGTTTTCCGCTCGCGATTATACCGCAGCGAATTTCAAGGCGTTGGCGTCGCGGTACGGCTTCAATGTAAG
CGCCTCCGCCCCTTCGAGTACATTGCTCGACGCAGCAGCAAGAGGTCTGCCCACTGTGGTTCGAGCCTCACCGCACTACT
ACAATACGGAAGATGAAATCGATAGTTTCACCCGTTTCGTACGGGATAGTCGACGCAAATAG

Upstream 100 bases:

>100_bases
AGTGGAAGGACTCACGCATCGAAAATCACGGCGGAGATTGATGCTTCCGAGAAAATGCGGGACTTCAGGTCGACCCCGTA
GAGCGAGTTGAGAATGTTCA

Downstream 100 bases:

>100_bases
GCTGTTTCCCAGAGACTTGAGGAGCTGCGAGAGGCACGCTTCCAAGCGCCGTACTGGGCAATATCCGGTCCGGTCTGCAA
CCGACATGAAGGCACAATGC

Product: classV aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MPIDLEKVRSETPGIRNRIHLNNAGAALMPNPVLEAMVGYLNREAEVGGYEAAGEAASELDGVYDSVARLLGCGRDEIAL
TENATVAWQLAFYALTFRPGDRILTARAEYAANYVAFLQIAKRTGASIEVIPSDDGGVLDPACLEQMLDERVKLIAITWV
PTNGGLRNPAAAVGAIARRHGITYLLDACQAVGQMPTRVEELGCDILTGTGRKFLRGPRGTGFLYIRRELLLTLEPPMID
HFAAPWVAPDRYELRRDARRFETWENNYAARLGLGRALDYALDLGLHEIENRCGNLSERLRNGLRNIEGVAVHDLGPKPA
SIVTFSARDYTAANFKALASRYGFNVSASAPSSTLLDAAARGLPTVVRASPHYYNTEDEIDSFTRFVRDSRRK

Sequences:

>Translated_393_residues
MPIDLEKVRSETPGIRNRIHLNNAGAALMPNPVLEAMVGYLNREAEVGGYEAAGEAASELDGVYDSVARLLGCGRDEIAL
TENATVAWQLAFYALTFRPGDRILTARAEYAANYVAFLQIAKRTGASIEVIPSDDGGVLDPACLEQMLDERVKLIAITWV
PTNGGLRNPAAAVGAIARRHGITYLLDACQAVGQMPTRVEELGCDILTGTGRKFLRGPRGTGFLYIRRELLLTLEPPMID
HFAAPWVAPDRYELRRDARRFETWENNYAARLGLGRALDYALDLGLHEIENRCGNLSERLRNGLRNIEGVAVHDLGPKPA
SIVTFSARDYTAANFKALASRYGFNVSASAPSSTLLDAAARGLPTVVRASPHYYNTEDEIDSFTRFVRDSRRK
>Mature_392_residues
PIDLEKVRSETPGIRNRIHLNNAGAALMPNPVLEAMVGYLNREAEVGGYEAAGEAASELDGVYDSVARLLGCGRDEIALT
ENATVAWQLAFYALTFRPGDRILTARAEYAANYVAFLQIAKRTGASIEVIPSDDGGVLDPACLEQMLDERVKLIAITWVP
TNGGLRNPAAAVGAIARRHGITYLLDACQAVGQMPTRVEELGCDILTGTGRKFLRGPRGTGFLYIRRELLLTLEPPMIDH
FAAPWVAPDRYELRRDARRFETWENNYAARLGLGRALDYALDLGLHEIENRCGNLSERLRNGLRNIEGVAVHDLGPKPAS
IVTFSARDYTAANFKALASRYGFNVSASAPSSTLLDAAARGLPTVVRASPHYYNTEDEIDSFTRFVRDSRRK

Specific function: Cysteine Desulfurases Mobilize The Sulfur From L- Cysteine To Yield L-Alanine, An Essential Step In Sulfur Metabolism For Biosynthesis Of A Variety Of Sulfur-Containing Biomolecules. Component Of The Suf Operon, Which Is Activated And Required Under Speci

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=204, Percent_Identity=27.4509803921569, Blast_Score=75, Evalue=8e-14,
Organism=Escherichia coli, GI1787970, Length=409, Percent_Identity=26.8948655256724, Blast_Score=131, Evalue=9e-32,
Organism=Escherichia coli, GI1789175, Length=390, Percent_Identity=24.3589743589744, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI48994898, Length=390, Percent_Identity=26.6666666666667, Blast_Score=95, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI25143064, Length=235, Percent_Identity=27.2340425531915, Blast_Score=82, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6319831, Length=176, Percent_Identity=29.5454545454545, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI20129463, Length=229, Percent_Identity=27.5109170305677, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 43137; Mature: 43006

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIDLEKVRSETPGIRNRIHLNNAGAALMPNPVLEAMVGYLNREAEVGGYEAAGEAASEL
CCCCHHHHHCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
DGVYDSVARLLGCGRDEIALTENATVAWQLAFYALTFRPGDRILTARAEYAANYVAFLQI
HHHHHHHHHHHCCCCCCEEEECCCEEEEEEEEEEEEECCCCCEEEEHHHHHHHHHHHHHH
AKRTGASIEVIPSDDGGVLDPACLEQMLDERVKLIAITWVPTNGGLRNPAAAVGAIARRH
HHHCCCEEEEEECCCCCCCCHHHHHHHHHCCEEEEEEEEEECCCCCCCHHHHHHHHHHHC
GITYLLDACQAVGQMPTRVEELGCDILTGTGRKFLRGPRGTGFLYIRRELLLTLEPPMID
CHHHHHHHHHHHCCCCHHHHHHCCCEEECCCHHHHCCCCCCCEEEEEEEHHEEECCCHHH
HFAAPWVAPDRYELRRDARRFETWENNYAARLGLGRALDYALDLGLHEIENRCGNLSERL
HHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
RNGLRNIEGVAVHDLGPKPASIVTFSARDYTAANFKALASRYGFNVSASAPSSTLLDAAA
HHHHHCCCCEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEECCCCCHHHHHHHH
RGLPTVVRASPHYYNTEDEIDSFTRFVRDSRRK
CCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PIDLEKVRSETPGIRNRIHLNNAGAALMPNPVLEAMVGYLNREAEVGGYEAAGEAASEL
CCCHHHHHCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
DGVYDSVARLLGCGRDEIALTENATVAWQLAFYALTFRPGDRILTARAEYAANYVAFLQI
HHHHHHHHHHHCCCCCCEEEECCCEEEEEEEEEEEEECCCCCEEEEHHHHHHHHHHHHHH
AKRTGASIEVIPSDDGGVLDPACLEQMLDERVKLIAITWVPTNGGLRNPAAAVGAIARRH
HHHCCCEEEEEECCCCCCCCHHHHHHHHHCCEEEEEEEEEECCCCCCCHHHHHHHHHHHC
GITYLLDACQAVGQMPTRVEELGCDILTGTGRKFLRGPRGTGFLYIRRELLLTLEPPMID
CHHHHHHHHHHHCCCCHHHHHHCCCEEECCCHHHHCCCCCCCEEEEEEEHHEEECCCHHH
HFAAPWVAPDRYELRRDARRFETWENNYAARLGLGRALDYALDLGLHEIENRCGNLSERL
HHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
RNGLRNIEGVAVHDLGPKPASIVTFSARDYTAANFKALASRYGFNVSASAPSSTLLDAAA
HHHHHCCCCEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEECCCCCHHHHHHHH
RGLPTVVRASPHYYNTEDEIDSFTRFVRDSRRK
CCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]