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The map label for this gene is yusZ [H]

Identifier: 150396427

GI number: 150396427

Start: 1292493

End: 1293305

Strand: Direct

Name: yusZ [H]

Synonym: Smed_1209

Alternate gene names: 150396427

Gene position: 1292493-1293305 (Clockwise)

Preceding gene: 150396426

Following gene: 150396428

Centisome position: 34.18

GC content: 58.67

Gene sequence:

>813_bases
ATGAGCAAGACTATCCTCATTACTGGCGCAGGATCTGGCTTCGGCAAGGCGGGCGCCATCGGCATGGCCAGGAACGGTCA
CAACATCATCGCGACCTGCCAGGTTTCGCCGCTGGTGACCTATCTTCGCGAAGAGGTCGAGAGGCTCGATCTTGGGAAGC
GAATCCGTGTGGAGAGGCTCGATCTGACGGACCCGTACGACATCAAGCAGGCCCAGAGCTGGGACTTCGACGTTCTCTGG
AACAATGCGGGGCAGGGCGAGCCGGGTCCCGTCTGGGAAATCCCCGTCGACATCGTTCGCCGCAACTTCGAGACGAACGT
CTTCCTGCCGCTGACGCTCACTCAGGGCGTCATCCAGCGCTGGATCCGCGAGGGCAAGCACCATGGAAAGAAGGTTGTCT
TCACCTCGTCGATGGGCGGCCTGTTCACCCCGGCAAACTGGGGCACCTATGTCTCGACGAAGCATGCGCTGGAGTCCATT
GCTGAAGCCCTGCAGCAGGAACTCGCCGCCTACGGCATCAAGATCCAGACCATCAATCCCGGTGCCTATTATACTGGGTA
TAACGAGACGATGGCCGACAATCCGTTCCGCTGGATGGACGACAGCAAGAACTTCACGAAGCGTGCCGATCTCCGGAAGG
GCTTCGATGACTTCTTCGCAACCCCGGAAGGGAAGATGGATCCCACCGAGATGATCGATCGCATGATTGAGATCGTTCCG
GCCGATACCGGCAAGTTCCGCAATGTCTGCCCGAAGGTCATCGAGGACATGTTGAAGGATCATCAGCTCAAGGCCTGGGA
AGCCCAGATTTGA

Upstream 100 bases:

>100_bases
CCATCGAACAGGATACCAAGATCGCCAAGGCCGGGCTCGCGGCCTTCGAGGCGACGCTACGCTAATCATCAACCCCACGA
GCATCTGAAGGGAGAATGAC

Downstream 100 bases:

>100_bases
AATCTGGCGGCGTTGCCCCGCCGCTCTCCTCCGCCGTCGGGACGGCCCGGCGGCACTCAACGCGATTCAAGGAGTTCAGA
GATGAGCAACAGCAAACTAT

Product: short chain dehydrogenase

Products: NA

Alternate protein names: ORFA [H]

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MSKTILITGAGSGFGKAGAIGMARNGHNIIATCQVSPLVTYLREEVERLDLGKRIRVERLDLTDPYDIKQAQSWDFDVLW
NNAGQGEPGPVWEIPVDIVRRNFETNVFLPLTLTQGVIQRWIREGKHHGKKVVFTSSMGGLFTPANWGTYVSTKHALESI
AEALQQELAAYGIKIQTINPGAYYTGYNETMADNPFRWMDDSKNFTKRADLRKGFDDFFATPEGKMDPTEMIDRMIEIVP
ADTGKFRNVCPKVIEDMLKDHQLKAWEAQI

Sequences:

>Translated_270_residues
MSKTILITGAGSGFGKAGAIGMARNGHNIIATCQVSPLVTYLREEVERLDLGKRIRVERLDLTDPYDIKQAQSWDFDVLW
NNAGQGEPGPVWEIPVDIVRRNFETNVFLPLTLTQGVIQRWIREGKHHGKKVVFTSSMGGLFTPANWGTYVSTKHALESI
AEALQQELAAYGIKIQTINPGAYYTGYNETMADNPFRWMDDSKNFTKRADLRKGFDDFFATPEGKMDPTEMIDRMIEIVP
ADTGKFRNVCPKVIEDMLKDHQLKAWEAQI
>Mature_269_residues
SKTILITGAGSGFGKAGAIGMARNGHNIIATCQVSPLVTYLREEVERLDLGKRIRVERLDLTDPYDIKQAQSWDFDVLWN
NAGQGEPGPVWEIPVDIVRRNFETNVFLPLTLTQGVIQRWIREGKHHGKKVVFTSSMGGLFTPANWGTYVSTKHALESIA
EALQQELAAYGIKIQTINPGAYYTGYNETMADNPFRWMDDSKNFTKRADLRKGFDDFFATPEGKMDPTEMIDRMIEIVPA
DTGKFRNVCPKVIEDMLKDHQLKAWEAQI

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40548397, Length=192, Percent_Identity=29.6875, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI214010158, Length=192, Percent_Identity=29.6875, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI214010156, Length=192, Percent_Identity=29.6875, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI22758144, Length=192, Percent_Identity=29.6875, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI20149619, Length=275, Percent_Identity=25.0909090909091, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI50726952, Length=190, Percent_Identity=29.4736842105263, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI7657478, Length=199, Percent_Identity=28.643216080402, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1786701, Length=217, Percent_Identity=29.9539170506912, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI87082100, Length=201, Percent_Identity=29.8507462686567, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787905, Length=189, Percent_Identity=28.5714285714286, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17570069, Length=194, Percent_Identity=28.3505154639175, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71997402, Length=194, Percent_Identity=27.8350515463918, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323882, Length=233, Percent_Identity=27.8969957081545, Blast_Score=66, Evalue=7e-12,
Organism=Drosophila melanogaster, GI116007236, Length=190, Percent_Identity=28.4210526315789, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21358495, Length=187, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI116007238, Length=183, Percent_Identity=27.8688524590164, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24580925, Length=239, Percent_Identity=26.3598326359833, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24641232, Length=235, Percent_Identity=26.8085106382979, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 30457; Mature: 30326

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTILITGAGSGFGKAGAIGMARNGHNIIATCQVSPLVTYLREEVERLDLGKRIRVERL
CCCEEEEEECCCCCCCCCCEEEECCCCEEEEEEEHHHHHHHHHHHHHHHCCCCCEEEEEE
DLTDPYDIKQAQSWDFDVLWNNAGQGEPGPVWEIPVDIVRRNFETNVFLPLTLTQGVIQR
CCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEECCHHHHHCCCCCCEEEEEHHHHHHHHH
WIREGKHHGKKVVFTSSMGGLFTPANWGTYVSTKHALESIAEALQQELAAYGIKIQTINP
HHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECC
GAYYTGYNETMADNPFRWMDDSKNFTKRADLRKGFDDFFATPEGKMDPTEMIDRMIEIVP
CCEECCCCCCCCCCCCEECCCCCCHHHHHHHHHCHHHHHCCCCCCCCHHHHHHHHHHHHC
ADTGKFRNVCPKVIEDMLKDHQLKAWEAQI
CCCCHHHHHHHHHHHHHHHHCCCCHHCCCC
>Mature Secondary Structure 
SKTILITGAGSGFGKAGAIGMARNGHNIIATCQVSPLVTYLREEVERLDLGKRIRVERL
CCEEEEEECCCCCCCCCCEEEECCCCEEEEEEEHHHHHHHHHHHHHHHCCCCCEEEEEE
DLTDPYDIKQAQSWDFDVLWNNAGQGEPGPVWEIPVDIVRRNFETNVFLPLTLTQGVIQR
CCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEECCHHHHHCCCCCCEEEEEHHHHHHHHH
WIREGKHHGKKVVFTSSMGGLFTPANWGTYVSTKHALESIAEALQQELAAYGIKIQTINP
HHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECC
GAYYTGYNETMADNPFRWMDDSKNFTKRADLRKGFDDFFATPEGKMDPTEMIDRMIEIVP
CCEECCCCCCCCCCCCEECCCCCCHHHHHHHHHCHHHHHCCCCCCCCHHHHHHHHHHHHC
ADTGKFRNVCPKVIEDMLKDHQLKAWEAQI
CCCCHHHHHHHHHHHHHHHHCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9384377; 8396117 [H]