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The map label for this gene is hflX [H]

Identifier: 150396315

GI number: 150396315

Start: 1165756

End: 1167153

Strand: Direct

Name: hflX [H]

Synonym: Smed_1096

Alternate gene names: 150396315

Gene position: 1165756-1167153 (Clockwise)

Preceding gene: 150396314

Following gene: 150396318

Centisome position: 30.82

GC content: 62.59

Gene sequence:

>1398_bases
GTGAGGAACATTACCAAGCGTGATTCAAAATCGTCGTCGATTATCCCGGAGCTTGAGCGGCTCCGTGATGACTCGCGTGC
CGTGGTCGTCGTCCCGGTCCTGAAAAAGGCCGGGAGGGTCTCTGCCGACATAGTGGCGCAGAGCGCCACGCGGTCGGATC
AAAGCCGCCTGGAGGAGGCGACCGGCCTGGCACTCGCCATCGATCTCGAAGTGGTTCACGGCATGGTCGTGCCCGTCGCC
CAGCCGAAGCCCGGCACTCTGCTCGGAACGGGCAAGATCGAGGAGATCGGTCACGTTCTGAGCGACAAGGATGCGGGGCT
CGTGATCGTCGATCACCCGTTGACGCCAGTCCAGCAGCGCAATCTCGAGAAGGAGTGGAACGCCAAGGTCATCGACCGGA
CCGGCCTCATTCTTGAAATCTTCGGTCGCCGCGCCTCCACCAGGGAAGGCACGCTGCAGGTGGATCTCGCCCATCTCAAC
TACCAGAAGGGCCGCCTCGTTCGCAGCTGGACGCACCTTGAGCGGCAGCGCGGCGGTGCGGGATTCATGGGCGGTCCCGG
TGAAACGCAGATCGAGGCCGACCGCCGCCTGCTGCAAGAGAGGATCGTCAAGCTCGAACGCGAGTTGGAGCAGGTGCGGC
GCACGCGTCAGCTTCACCGCTCGAAGCGCAAGAAGGTGCCGCATCCGATCGTCGCGCTCGTCGGCTATACGAATGCTGGA
AAATCCACGCTCTTCAACCGGATGACCGGCGCCGGCGTTCTTGCCGAGGATATGCTCTTCGCAACGCTGGATCCGACGCT
CAGGCGGCTGAAGCTGCCGCATGGGCGCATGGTCATCCTTTCCGATACCGTCGGCTTCATTTCCGACCTGCCGACGCACC
TGGTTGCCGCTTTCCGGGCGACATTGGAAGAGGTGCTCGAGGCCGACCTGATACTGCATGTACGCGACCTGTCCGATCCC
GATAATCAGGCACAGGCGAGCGACGTGCTGCGCATCCTCTCCGATCTCGGCATCGACGAGAAGGAGGGCGCCGAGCGCAT
TGTCGAGGTCTGGAACAAGATCGACAAGGTTGAGCCGGAGGTGCGCGAGGTTCTGGTGAAGAAGGCGGCAAGCGTCGACA
ACACAGTCGCCGTTTCCGCCATGACCGGCGAAGGTGTCGGGGAGCTTCTCACCGAAATCGGTCGACGCCTGTCAGGAGTC
ATGACCGAATGCACCATCGTTCTTGGGCTCGACCAGCTGCAGTTTCTGCCTTGGGTCTACCAGCACGCTATCGTCGATGC
ACGCGAAGATCTCGAGGATGGACGTGTGAGTCTGGACCTGCGCCTGACCGAAGGCGAGGCGGTCGAACTCGAACGCCGGC
TGGGCAACGGCCCGAAGGCTGTCGAAGAGGACTGGTAG

Upstream 100 bases:

>100_bases
CGGCCATTCTCAGCTCGTCTACAAGCACGCCATCTCGACGATCATGCCGGGCCAGCCGCTGCAGATGTTCGAGAATGAGG
AAGCTGCCTCCTGACGGGAC

Downstream 100 bases:

>100_bases
CGGGTAAGAGCGCGCCGCGTTCCTCTTGTTCGACGCAGAAGAGTCTTTCAACCCAAGAACTTGCGCCGCGGTGGGAGCAG
CGGAGAACGCGGCTCGCTTA

Product: HSR1-like GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MRNITKRDSKSSSIIPELERLRDDSRAVVVVPVLKKAGRVSADIVAQSATRSDQSRLEEATGLALAIDLEVVHGMVVPVA
QPKPGTLLGTGKIEEIGHVLSDKDAGLVIVDHPLTPVQQRNLEKEWNAKVIDRTGLILEIFGRRASTREGTLQVDLAHLN
YQKGRLVRSWTHLERQRGGAGFMGGPGETQIEADRRLLQERIVKLERELEQVRRTRQLHRSKRKKVPHPIVALVGYTNAG
KSTLFNRMTGAGVLAEDMLFATLDPTLRRLKLPHGRMVILSDTVGFISDLPTHLVAAFRATLEEVLEADLILHVRDLSDP
DNQAQASDVLRILSDLGIDEKEGAERIVEVWNKIDKVEPEVREVLVKKAASVDNTVAVSAMTGEGVGELLTEIGRRLSGV
MTECTIVLGLDQLQFLPWVYQHAIVDAREDLEDGRVSLDLRLTEGEAVELERRLGNGPKAVEEDW

Sequences:

>Translated_465_residues
MRNITKRDSKSSSIIPELERLRDDSRAVVVVPVLKKAGRVSADIVAQSATRSDQSRLEEATGLALAIDLEVVHGMVVPVA
QPKPGTLLGTGKIEEIGHVLSDKDAGLVIVDHPLTPVQQRNLEKEWNAKVIDRTGLILEIFGRRASTREGTLQVDLAHLN
YQKGRLVRSWTHLERQRGGAGFMGGPGETQIEADRRLLQERIVKLERELEQVRRTRQLHRSKRKKVPHPIVALVGYTNAG
KSTLFNRMTGAGVLAEDMLFATLDPTLRRLKLPHGRMVILSDTVGFISDLPTHLVAAFRATLEEVLEADLILHVRDLSDP
DNQAQASDVLRILSDLGIDEKEGAERIVEVWNKIDKVEPEVREVLVKKAASVDNTVAVSAMTGEGVGELLTEIGRRLSGV
MTECTIVLGLDQLQFLPWVYQHAIVDAREDLEDGRVSLDLRLTEGEAVELERRLGNGPKAVEEDW
>Mature_465_residues
MRNITKRDSKSSSIIPELERLRDDSRAVVVVPVLKKAGRVSADIVAQSATRSDQSRLEEATGLALAIDLEVVHGMVVPVA
QPKPGTLLGTGKIEEIGHVLSDKDAGLVIVDHPLTPVQQRNLEKEWNAKVIDRTGLILEIFGRRASTREGTLQVDLAHLN
YQKGRLVRSWTHLERQRGGAGFMGGPGETQIEADRRLLQERIVKLERELEQVRRTRQLHRSKRKKVPHPIVALVGYTNAG
KSTLFNRMTGAGVLAEDMLFATLDPTLRRLKLPHGRMVILSDTVGFISDLPTHLVAAFRATLEEVLEADLILHVRDLSDP
DNQAQASDVLRILSDLGIDEKEGAERIVEVWNKIDKVEPEVREVLVKKAASVDNTVAVSAMTGEGVGELLTEIGRRLSGV
MTECTIVLGLDQLQFLPWVYQHAIVDAREDLEDGRVSLDLRLTEGEAVELERRLGNGPKAVEEDW

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=240, Percent_Identity=38.75, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI310133116, Length=269, Percent_Identity=37.1747211895911, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI310124269, Length=250, Percent_Identity=37.6, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI310124267, Length=250, Percent_Identity=37.6, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI310124171, Length=250, Percent_Identity=37.6, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI310124169, Length=250, Percent_Identity=37.6, Blast_Score=141, Evalue=1e-33,
Organism=Escherichia coli, GI1790615, Length=390, Percent_Identity=44.6153846153846, Blast_Score=285, Evalue=4e-78,
Organism=Caenorhabditis elegans, GI17561038, Length=444, Percent_Identity=32.2072072072072, Blast_Score=192, Evalue=3e-49,
Organism=Drosophila melanogaster, GI24650079, Length=402, Percent_Identity=33.3333333333333, Blast_Score=150, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 51553; Mature: 51553

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNITKRDSKSSSIIPELERLRDDSRAVVVVPVLKKAGRVSADIVAQSATRSDQSRLEEA
CCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEECHHHCCCCHHHHHHHHHCCCHHHHHHHH
TGLALAIDLEVVHGMVVPVAQPKPGTLLGTGKIEEIGHVLSDKDAGLVIVDHPLTPVQQR
CCEEEEEEHHHHCCEEEECCCCCCCCEEECCCHHHHHHHHCCCCCCEEEECCCCCCHHHH
NLEKEWNAKVIDRTGLILEIFGRRASTREGTLQVDLAHLNYQKGRLVRSWTHLERQRGGA
CCCHHCCCEEECCCCHHHHHHCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCC
GFMGGPGETQIEADRRLLQERIVKLERELEQVRRTRQLHRSKRKKVPHPIVALVGYTNAG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
KSTLFNRMTGAGVLAEDMLFATLDPTLRRLKLPHGRMVILSDTVGFISDLPTHLVAAFRA
HHHHHHHHCCCCHHHHHHHHHHHCHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHH
TLEEVLEADLILHVRDLSDPDNQAQASDVLRILSDLGIDEKEGAERIVEVWNKIDKVEPE
HHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHH
VREVLVKKAASVDNTVAVSAMTGEGVGELLTEIGRRLSGVMTECTIVLGLDQLQFLPWVY
HHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHH
QHAIVDAREDLEDGRVSLDLRLTEGEAVELERRLGNGPKAVEEDW
HHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MRNITKRDSKSSSIIPELERLRDDSRAVVVVPVLKKAGRVSADIVAQSATRSDQSRLEEA
CCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEECHHHCCCCHHHHHHHHHCCCHHHHHHHH
TGLALAIDLEVVHGMVVPVAQPKPGTLLGTGKIEEIGHVLSDKDAGLVIVDHPLTPVQQR
CCEEEEEEHHHHCCEEEECCCCCCCCEEECCCHHHHHHHHCCCCCCEEEECCCCCCHHHH
NLEKEWNAKVIDRTGLILEIFGRRASTREGTLQVDLAHLNYQKGRLVRSWTHLERQRGGA
CCCHHCCCEEECCCCHHHHHHCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCC
GFMGGPGETQIEADRRLLQERIVKLERELEQVRRTRQLHRSKRKKVPHPIVALVGYTNAG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
KSTLFNRMTGAGVLAEDMLFATLDPTLRRLKLPHGRMVILSDTVGFISDLPTHLVAAFRA
HHHHHHHHCCCCHHHHHHHHHHHCHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHH
TLEEVLEADLILHVRDLSDPDNQAQASDVLRILSDLGIDEKEGAERIVEVWNKIDKVEPE
HHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHH
VREVLVKKAASVDNTVAVSAMTGEGVGELLTEIGRRLSGVMTECTIVLGLDQLQFLPWVY
HHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHH
QHAIVDAREDLEDGRVSLDLRLTEGEAVELERRLGNGPKAVEEDW
HHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]